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  1. AU="Carsten Schmidt-Weber"
  2. AU="Song, Hui rong"
  3. AU="Ihuegbu, Nnamdi"
  4. AU="Berger, Jacob"
  5. AU="Shea, Martin J"
  6. AU="Vecchié, Alessandra"

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  1. Article: Errors in determining the flow rate of Hirst-type pollen traps

    Oteros, Jose / Jeroen Buters / Gottfried Laven / Stefani Röseler / Reinhard Wachter / Carsten Schmidt-Weber / Frieder Hofmann

    Aerobiologia. 2017 June, v. 33, no. 2

    2017  

    Abstract: Standardisation of methods of pollen monitoring networks is vital for data quality. In pollen monitoring networks in Europe, the Hirst-type trap is standard. Hirst traps are calibrated with handheld rotameters. We detected a systematic error in the flow ... ...

    Abstract Standardisation of methods of pollen monitoring networks is vital for data quality. In pollen monitoring networks in Europe, the Hirst-type trap is standard. Hirst traps are calibrated with handheld rotameters. We detected a systematic error in the flow rate calibrated by these standard handheld rotameters. We measured the flow rate of 19 Hirst traps from three commercial brands during calibration but also during monitoring. We used three different rotameters supplied by the manufacturers of the traps, respectively. The actual air flow rate was measured using an electronic heat anemometer with negligible air flow resistance. After calibration to 10 l/min, the rotameter was removed, which led to a significant increase in the flow rate in the range of 10.5–17.2 l/min, a systematic error between 5 and 72%. No significant difference was found between the different commercial trap brands. The analysis revealed that the error depended on the type of the rotameter and the individual trap. The error may be explained by the additional air flow resistance of each rotameter. The total resistance of the system—trap plus rotameter—is higher during calibration when the rotameter is held on the inlet compared to the routine monitoring without the rotameter. Depending on the characteristic curve of the suction pump in the trap (fan), the air flow rate increases to values considerably higher than 10 l/min. Thus, monitoring is done under a higher flow rate than that was calibrated. In order to obtain comparable data within a monitoring network, a solution for correction of this systematic error seems advisable, preferably in cooperation with the manufacturers.
    Keywords air flow ; flow resistance ; heat ; monitoring ; pollen ; spore traps ; traps ; Europe
    Language English
    Dates of publication 2017-06
    Size p. 201-210.
    Publishing place Springer Netherlands
    Document type Article
    ZDB-ID 1499126-3
    ISSN 1573-3025 ; 0393-5965
    ISSN (online) 1573-3025
    ISSN 0393-5965
    DOI 10.1007/s10453-016-9467-x
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Seasonal variation of birch and grass pollen loads and allergen release at two sites in the German Alps

    Jochner, Susanne / Annette Menzel / Carsten Schmidt-Weber / Claudia Traidl-Hoffmann / Gudrun Pusch / Ingrid Weichenmeier / Jeroen T.M. Buters / Julia Laube / Marvin Lüpke

    Atmospheric environment. 2015 Dec., v. 122

    2015  

    Abstract: Less vegetated mountainous areas may provide better conditions for allergy sufferers. However, atmospheric transport can result in medically relevant pollen loads in such regions. The majority of investigations has focused on the pollen load, expressed ... ...

    Abstract Less vegetated mountainous areas may provide better conditions for allergy sufferers. However, atmospheric transport can result in medically relevant pollen loads in such regions. The majority of investigations has focused on the pollen load, expressed as daily averages of pollen per cubic meter of air (pollen grains/m³); however, the severity of allergic symptoms is also determined by the actual allergen content of this pollen, its pollen potency, which may differ between high and low altitudes. We analysed airborne birch and grass pollen concentrations along with allergen content (birch: Bet v 1, grass: Phl p 5) at two different altitudes (734 and 2650 m a.s.l.) in the Zugspitze region (2009–2010). Back-trajectories were calculated for the high altitude site and for specific days with abrupt increases in pollen potency. We observed several days with medically relevant pollen concentrations at the highest site. In addition, a few days with pollen were not associated with allergens and vice versa. The calculated seasonal mean allergen release per pollen grain was 1.8–3.3 pg Bet v 1 and 5.7 pg Phl p 5 in the valley and 1.1–3.7 pg Bet v 1 and 0.7–1.5 pg Phl p 5 at the high altitude site. Back-trajectories revealed that high pollen potency at the higher site was generally associated with south-westerly to south-easterly (birch), or northerly (grass) wind directions. By investigating days with sudden increases in pollen potency, however, it was difficult to draw definitive conclusions on long- or short-range transport. Our findings suggest that people allergic to pollen might suffer less at higher altitudes and further indicate that a risk assessment relying on the actual concentration of airborne pollen does not necessarily reflect the actual allergy exposure of individuals.
    Keywords air ; allergens ; altitude ; atmospheric chemistry ; Betula ; grasses ; hypersensitivity ; people ; pollen ; risk assessment ; seasonal variation ; wind direction ; Alps region
    Language English
    Dates of publication 2015-12
    Size p. 83-93.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 216368-8
    ISSN 0004-6981 ; 1352-2310
    ISSN 0004-6981 ; 1352-2310
    DOI 10.1016/j.atmosenv.2015.08.031
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice

    Kan Xie / Helmut Fuchs / Enzo Scifo / Dan Liu / Ahmad Aziz / Juan Antonio Aguilar-Pimentel / Oana Veronica Amarie / Lore Becker / Patricia da Silva-Buttkus / Julia Calzada-Wack / Yi-Li Cho / Yushuang Deng / A. Cole Edwards / Lillian Garrett / Christina Georgopoulou / Raffaele Gerlini / Sabine M. Hölter / Tanja Klein-Rodewald / Michael Kramer /
    Stefanie Leuchtenberger / Dimitra Lountzi / Phillip Mayer-Kuckuk / Lena L. Nover / Manuela A. Oestereicher / Clemens Overkott / Brandon L. Pearson / Birgit Rathkolb / Jan Rozman / Jenny Russ / Kristina Schaaf / Nadine Spielmann / Adrián Sanz-Moreno / Claudia Stoeger / Irina Treise / Daniele Bano / Dirk H. Busch / Jochen Graw / Martin Klingenspor / Thomas Klopstock / Beverly A. Mock / Paolo Salomoni / Carsten Schmidt-Weber / Marco Weiergräber / Eckhard Wolf / Wolfgang Wurst / Valérie Gailus-Durner / Monique M. B. Breteler / Martin Hrabě de Angelis / Dan Ehninger

    Nature Communications, Vol 13, Iss 1, Pp 1-

    2022  Volume 29

    Abstract: Lifespan can be affected by both physiological ageing and specific sets of pathologies associated with old age. Here the authors report a resource of large-scale cross-sectional phenotyping of aging male mice at different time points to analyse a large ... ...

    Abstract Lifespan can be affected by both physiological ageing and specific sets of pathologies associated with old age. Here the authors report a resource of large-scale cross-sectional phenotyping of aging male mice at different time points to analyse a large set of phenotypes and molecular markers, including during genetic and diet interventions affecting lifespan.
    Keywords Science ; Q
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: High environmental ozone levels lead to enhanced allergenicity of birch pollen.

    Isabelle Beck / Susanne Jochner / Stefanie Gilles / Mareike McIntyre / Jeroen T M Buters / Carsten Schmidt-Weber / Heidrun Behrendt / Johannes Ring / Annette Menzel / Claudia Traidl-Hoffmann

    PLoS ONE, Vol 8, Iss 11, p e

    2013  Volume 80147

    Abstract: Background Evidence is compelling for a positive correlation between climate change, urbanisation and prevalence of allergic sensitisation and diseases. The reason for this association is not clear to date. Some data point to a pro-allergenic effect of ... ...

    Abstract Background Evidence is compelling for a positive correlation between climate change, urbanisation and prevalence of allergic sensitisation and diseases. The reason for this association is not clear to date. Some data point to a pro-allergenic effect of anthropogenic factors on susceptible individuals. Objectives To evaluate the impact of urbanisation and climate change on pollen allergenicity. Methods Catkins were sampled from birch trees from different sites across the greater area of Munich, pollen were isolated and an urbanisation index, NO2 and ozone exposure were determined. To estimate pollen allergenicity, allergen content and pollen-associated lipid mediators were measured in aqueous pollen extracts. Immune stimulatory and modulatory capacity of pollen was assessed by neutrophil migration assays and the potential of pollen to inhibit dendritic cell interleukin-12 response. In vivo allergenicity was assessed by skin prick tests. Results The study revealed ozone as a prominent environmental factor influencing the allergenicity of birch pollen. Enhanced allergenicity, as assessed in skin prick tests, was mirrored by enhanced allergen content. Beyond that, ozone induced changes in lipid composition and chemotactic and immune modulatory potential of the pollen. Higher ozone-exposed pollen was characterised by less immune modulatory but higher immune stimulatory potential. Conclusion It is likely that future climate change along with increasing urbanisation will lead to rising ozone concentrations in the next decades. Our study indicates that ozone is a crucial factor leading to clinically relevant enhanced allergenicity of birch pollen. Thus, with increasing temperatures and increasing ozone levels, also symptoms of pollen allergic patients may increase further.
    Keywords Medicine ; R ; Science ; Q
    Subject code 333 ; 580
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain

    Polyxeni Nikolakopoulou / Antonios Chatzigeorgiou / Ioannis Kourtzelis / Louiza Toutouna / Jimmy Masjkur / Carina Arps-Forker / Steven W. Poser / Jan Rozman / Birgit Rathkolb / Juan Antonio Aguilar-Pimentel / German Mouse Clinic Consortium / Eckhard Wolf / Martin Klingenspor / Markus Ollert / Carsten Schmidt-Weber / Helmut Fuchs / Valerie Gailus-Durner / Martin Hrabe de Angelis / Vasiliki Tsata /
    Laura Sebastian Monasor / Maria Troullinaki / Anke Witt / Vivian Anastasiou / George Chrousos / Chun-Xia Yi / Cristina García-Cáceres / Matthias H. Tschöp / Stefan R. Bornstein / Andreas Androutsellis-Theotokis

    Scientific Reports, Vol 8, Iss 1, Pp 1-

    2018  Volume 15

    Abstract: Abstract Diabetes mellitus is a group of disorders characterized by prolonged high levels of circulating blood glucose. Type 1 diabetes is caused by decreased insulin production in the pancreas whereas type 2 diabetes may develop due to obesity and lack ... ...

    Abstract Abstract Diabetes mellitus is a group of disorders characterized by prolonged high levels of circulating blood glucose. Type 1 diabetes is caused by decreased insulin production in the pancreas whereas type 2 diabetes may develop due to obesity and lack of exercise; it begins with insulin resistance whereby cells fail to respond properly to insulin and it may also progress to decreased insulin levels. The brain is an important target for insulin, and there is great interest in understanding how diabetes affects the brain. In addition to the direct effects of insulin on the brain, diabetes may also impact the brain through modulation of the inflammatory system. Here we investigate how perturbation of circulating insulin levels affects the expression of Hes3, a transcription factor expressed in neural stem and progenitor cells that is involved in tissue regeneration. Our data show that streptozotocin-induced β-cell damage, high fat diet, as well as metformin, a common type 2 diabetes medication, regulate Hes3 levels in the brain. This work suggests that Hes3 is a valuable biomarker helping to monitor the state of endogenous neural stem and progenitor cells in the context of diabetes mellitus.
    Keywords Medicine ; R ; Science ; Q
    Subject code 571
    Language English
    Publishing date 2018-07-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.

    Viola André / Christine Gau / Angelika Scheideler / Juan A Aguilar-Pimentel / Oana V Amarie / Lore Becker / Lillian Garrett / Wolfgang Hans / Sabine M Hölter / Dirk Janik / Kristin Moreth / Frauke Neff / Manuela Östereicher / Ildiko Racz / Birgit Rathkolb / Jan Rozman / Raffi Bekeredjian / Jochen Graw / Martin Klingenspor /
    Thomas Klopstock / Markus Ollert / Carsten Schmidt-Weber / Eckhard Wolf / Wolfgang Wurst / Valérie Gailus-Durner / Markus Brielmeier / Helmut Fuchs / Martin Hrabé de Angelis

    PLoS Biology, Vol 16, Iss 4, p e

    2018  Volume 2005019

    Abstract: Animal welfare requires the adequate housing of animals to ensure health and well-being. The application of environmental enrichment is a way to improve the well-being of laboratory animals. However, it is important to know whether these enrichment items ...

    Abstract Animal welfare requires the adequate housing of animals to ensure health and well-being. The application of environmental enrichment is a way to improve the well-being of laboratory animals. However, it is important to know whether these enrichment items can be incorporated in experimental mouse husbandry without creating a divide between past and future experimental results. Previous small-scale studies have been inconsistent throughout the literature, and it is not yet completely understood whether and how enrichment might endanger comparability of results of scientific experiments. Here, we measured the effect on means and variability of 164 physiological parameters in 3 conditions: with nesting material with or without a shelter, comparing these 2 conditions to a "barren" regime without any enrichments. We studied a total of 360 mice from each of 2 mouse strains (C57BL/6NTac and DBA/2NCrl) and both sexes for each of the 3 conditions. Our study indicates that enrichment affects the mean values of some of the 164 parameters with no consistent effects on variability. However, the influence of enrichment appears negligible compared to the effects of other influencing factors. Therefore, nesting material and shelters may be used to improve animal welfare without impairment of experimental outcome or loss of comparability to previous data collected under barren housing conditions.
    Keywords Biology (General) ; QH301-705.5
    Subject code 630
    Language English
    Publishing date 2018-04-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice

    Kan Xie / Frauke Neff / Astrid Markert / Jan Rozman / Juan Antonio Aguilar-Pimentel / Oana Veronica Amarie / Lore Becker / Robert Brommage / Lillian Garrett / Kristin S. Henzel / Sabine M. Hölter / Dirk Janik / Isabelle Lehmann / Kristin Moreth / Brandon L. Pearson / Ildiko Racz / Birgit Rathkolb / Devon P. Ryan / Susanne Schröder /
    Irina Treise / Raffi Bekeredjian / Dirk H. Busch / Jochen Graw / Gerhard Ehninger / Martin Klingenspor / Thomas Klopstock / Markus Ollert / Michael Sandholzer / Carsten Schmidt-Weber / Marco Weiergräber / Eckhard Wolf / Wolfgang Wurst / Andreas Zimmer / Valerie Gailus-Durner / Helmut Fuchs / Martin Hrabě de Angelis / Dan Ehninger

    Nature Communications, Vol 8, Iss 1, Pp 1-

    2017  Volume 19

    Abstract: Dietary restriction can extend the life of various model organisms. Here, Xie et al. show that intermittent periods of fasting achieved through every-other-day feeding protect mice against neoplastic disease but do not broadly delay organismal aging in ... ...

    Abstract Dietary restriction can extend the life of various model organisms. Here, Xie et al. show that intermittent periods of fasting achieved through every-other-day feeding protect mice against neoplastic disease but do not broadly delay organismal aging in animals.
    Keywords Science ; Q
    Language English
    Publishing date 2017-07-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions.

    Sebastian Oeder / Tamara Kanashova / Olli Sippula / Sean C Sapcariu / Thorsten Streibel / Jose Manuel Arteaga-Salas / Johannes Passig / Marco Dilger / Hanns-Rudolf Paur / Christoph Schlager / Sonja Mülhopt / Silvia Diabaté / Carsten Weiss / Benjamin Stengel / Rom Rabe / Horst Harndorf / Tiina Torvela / Jorma K Jokiniemi / Maija-Riitta Hirvonen /
    Carsten Schmidt-Weber / Claudia Traidl-Hoffmann / Kelly A BéruBé / Anna J Wlodarczyk / Zoë Prytherch / Bernhard Michalke / Tobias Krebs / André S H Prévôt / Michael Kelbg / Josef Tiggesbäumker / Erwin Karg / Gert Jakobi / Sorana Scholtes / Jürgen Schnelle-Kreis / Jutta Lintelmann / Georg Matuschek / Martin Sklorz / Sophie Klingbeil / Jürgen Orasche / Patrick Richthammer / Laarnie Müller / Michael Elsasser / Ahmed Reda / Thomas Gröger / Benedikt Weggler / Theo Schwemer / Hendryk Czech / Christopher P Rüger / Gülcin Abbaszade / Christian Radischat / Karsten Hiller

    PLoS ONE, Vol 10, Iss 6, p e

    2015  Volume 0126536

    Abstract: BACKGROUND:Ship engine emissions are important with regard to lung and cardiovascular diseases especially in coastal regions worldwide. Known cellular responses to combustion particles include oxidative stress and inflammatory signalling. OBJECTIVES:To ... ...

    Abstract BACKGROUND:Ship engine emissions are important with regard to lung and cardiovascular diseases especially in coastal regions worldwide. Known cellular responses to combustion particles include oxidative stress and inflammatory signalling. OBJECTIVES:To provide a molecular link between the chemical and physical characteristics of ship emission particles and the cellular responses they elicit and to identify potentially harmful fractions in shipping emission aerosols. METHODS:Through an air-liquid interface exposure system, we exposed human lung cells under realistic in vitro conditions to exhaust fumes from a ship engine running on either common heavy fuel oil (HFO) or cleaner-burning diesel fuel (DF). Advanced chemical analyses of the exhaust aerosols were combined with transcriptional, proteomic and metabolomic profiling including isotope labelling methods to characterise the lung cell responses. RESULTS:The HFO emissions contained high concentrations of toxic compounds such as metals and polycyclic aromatic hydrocarbon, and were higher in particle mass. These compounds were lower in DF emissions, which in turn had higher concentrations of elemental carbon ("soot"). Common cellular reactions included cellular stress responses and endocytosis. Reactions to HFO emissions were dominated by oxidative stress and inflammatory responses, whereas DF emissions induced generally a broader biological response than HFO emissions and affected essential cellular pathways such as energy metabolism, protein synthesis, and chromatin modification. CONCLUSIONS:Despite a lower content of known toxic compounds, combustion particles from the clean shipping fuel DF influenced several essential pathways of lung cell metabolism more strongly than particles from the unrefined fuel HFO. This might be attributable to a higher soot content in DF. Thus the role of diesel soot, which is a known carcinogen in acute air pollution-induced health effects should be further investigated. For the use of HFO and DF we recommend a reduction of ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 571
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: 6th International Symposium on Molecular Allergology (ISMA)

    Christiane Hilger / Kyra Swiontek / Jörg Fischer / François Hentges / Christiane Lehners / Martine Morisset / Bernadette Eberlein / Tilo Biedermann / Markus Ollert / Sabrina Wildner / Teresa Stemeseder / Regina Freier / Peter Briza / Roland Lang / Eva Batanero / Mayte Villalba / Jonas Lidholm / Thomas Hawranek / Fatima Ferreira /
    Hans Brandstetter / Gabriele Gadermaier / Philippe Moingeon / Rachel Groeme / Julien Bouley / Véronique Bordas / Maxime Le Mignon / Laetitia Bussières / Aurélie Lautrette / Laurent Mascarell / Vincent Lombardi / Véronique Baron-Bodo / Henri Chabre / Thierry Batard / Emmanuel Nony / Karine Marafigo De Amicis / Alexandra Sayuri Watanabe / Daniele Danella Figo / José Roberto Aparecido Dos Santos-Pinto / Mario Sergio Palma / Fabio Fernandes Morato Castro / Jorge Kalil / Therese Wohlschlager / Fatima Ferreira-Briza / Keity Souza Santos / Margaretha Faber / Athina Van Gasse / Vito Sabato / Margo M. Hagendorens / Chris H. Bridts / Luc S. De Clerck / Araceli Diaz Perales / Didier Ebo / Petra Zavadakova / Aurélie Buchwalder / Fabien Rebeaud / Iwan Märki / Barbara Gepp / Nina Lengger / Christian Möbs / Wolfgang Pfützner / Christian Radauer / Barbara Bohle / Clovis Eduardo Galvao / Jose Roberto Aparecido Santos-Pinto / Christian Schwager / Skadi Kull / Frauke Schocker / Jochen Behrends / Wolf-Meinhard Becker / Uta Jappe / Carla Mastrorilli / Salvatore Tripodi / Carlo Caffarelli / Riccardo Asero / Arianna Dondi / Giampaolo Ricci / Carlotta Povesi Dascola / Elisabetta Calamelli / Andrea Di Rienzo Businco / Annamaria Bianchi / Tullio Frediani / Carmen Verga / Iride Dello Iacono / Diego Peroni / Giuseppe Pingitore / Roberto Bernardini / Paolo Maria Matricardi / Heidi Hofer / Claudia Asam / Michael Hauser / Martin Himly / Christof Ebner / Pierrick Lemoine / Karine Jain / Kathy Abiteboul / Monica Arvidsson / Sabina Rak / Inês Mota / Filipe Benito Garcia / Angela Gaspar / Cristina Arêde / Susana Piedade / Graça Sampaio / Graça Pires / Luís Miguel Borrego / Cristina Santa-Marta / Mário Morais-Almeida / Florin-Dan Popescu / Mariana Vieru / Florin-Adrian Secureanu / Rosa Anita Rodrigues Fernandes / Isabel Carrapatoso / Raquel Gomes / Celso Pereira / Ana Todo-Bom / María Cecilia Martín Fernández De Basoa / Javier Barrios Regio / Juan De Castro Cordova / Antón Fernández Ferreiro / Olympia Tsilochristou / Serena Perna / Alina Schwarz / Alexander Rohrbach / Antonio Cappella / Laura Hatzler / Carl-Peter Bauer / Ute Hoffmann / Johannes Forster / Fred Zepp / Antje Schuster / Raffael D’amelio / Ulrich Wahn / Thomas Keil / Susanne Lau / Pol André Apoil / Claire Mailhol / Anne Broué-Chabbert / Agnès Juchet / Alain Didier / Elodie Carrer / Thomas Lanot / Antoine Blancher / Almedina Kurtaj / Christoph Hillebrand / Gerda Fichtinger / Martin Danzer / Christian Gabriel / Theresa Thalhamer / Sandra Scheiblhofer / Josef Thalhamer / Richard Weiss / Martin Wolf / Ulrike Pichler / Teresa Twaroch / Hidenori Yokoi / Toshiro Takai / Alain Didierlaurent / Adriano Mari / Heidrun Behrendt / Angela Neubauer / Frank Stolz / Fátima Ferreira / Michael Wallner / Sara Carvalho / Tatiana Lourenço / Joana Cosme / Fátima Cabral Duarte / Amélia Spínola Santos / Ana Célia Costa / Manuel Pereira Barbosa / Eva Klinglmayr / Bettina Schweidler / Lisa Lueftenegger / Stephanie Moser / Patrick Doppler / Gertie J. Oostingh / Arne Bathke / Joerg Zumbach / Petr Panzner / Martina Vachova / Tomas Vlas / Marek Maly / Daniela Posa / Stephanie Hofmaier / Philippe Stock / Linus Grabenhenrich / Kuan-Wei Chen / Yvonne Resch / Susanne Vrtala / Rudolf Valenta / Tamar Abramidze / Nino Lomidze / Maia Gotua / Austeja Dapkeviciute / Ruta Einikyte / Jolita Norkuniene / Laima Skrickiene / Asta Miskiniene / Violeta Kvedariene / Maximilian Schiener / Carmen Moreno-Aguilar / Gunilla Pietsch / Mareike Mc Intyre / Lea Schwarze / Dennis Rußkamp / Edzard Spillner / Ulf Darsow / Carsten Schmidt-Weber / Simon Blank / Cyril Longé / Andrea Brazdova / Jean-Louis Brunet / Claire Schwartz / Bruno Girodet / François Lavaud / Joelle Birnbaum / Nhân Pham Thi / Magalie Duchateau / Julia Chamot-Rooke / Laurence Guilloux / Marie-Ange Selva / Rémy Couderc / Hélène Sénéchal / Jean-Pierre Sutra / Pascal Poncet / Steffen Augustin / Linda Pump / Martin Wald / Thomas Eichhorn / Frank Fischer / Christoph Willers / Michaela Miehe / Melanie Plum / Sara Wolf / Frederic Jabs / Tim Raiber / Frank Bantleon / Henning Seismann / Thilo Jakob / Danijela Apostolovic / Anh Thu Tran / Sara Sanchez-Vidaurre / Tanja Cirkovic Velickovic / Maria Starkhammar / Carl Hamsten / Marianne Van Hage / Pawel Dubiela / Piotr Humeniuk / Sabine Pfeifer / Merima Bublin / Tomasz Borowski / Karin Hoffmann-Sommergruber / Martie C. M. Verschuren / Shanna Bastiaan-Net / Defien Depoortere / Kay Foetisch / Stephan Scheurer / Harry J Wichers / Theo Noij / Nikki M.E. Van Uden / Karel Vandenberghe / Harry J. Wichers / Theo H. M. Noij / Anargyros Roulias / Maria Alejandra Parigiani / Linda Ahammer / Sarina Grutsch / Martin Tollinger / Raquel Moya / Mª Angeles López-Matas / Raquel Reyes / Jerónimo Carnés / Colette Larré / Hélène Rogniaux / Roberta Lupi / Sandra Denery-Papini / Isabel Maria Pablos / Stephanie Eichhorn / Yoan Machado / Jung-Won Park / Naveen Arora / Stefan Vieths / Charlene Tanaka / Florence Pineau / Martine Drouet / Etienne Beaudouin / Susan Altenbach / Hamza Mameri / Chantal Brossard / Jean Charles Gaudin / Denise Anne Moneret-Vautrin / Evelyne Paty / Olivier Tranquet / Stefania Masci / Denise-Anne Moneret-Vautrin / Arnd Petersen / Marisa Böttger / Sandra Rennert / Susanne Krause / Martin Ernst / Thomas Gutsmann / Johann Bauer / Buko Lindner / Stef Koppelman / Shyamali Jayasena / Dion Luykx / Erik Schepens / Govardus De Jong / Tom Isleib / Julie Nordlee / Joe Baumert / Steve Taylor / Soheila Maleki / Chiara Palladino / Sofía Sirvent / Alba Angelina / Thomas Eiwegger / Oscar Palomares / Heimo Breiteneder / Mathilde Claude / Grégory Bouchaud / Marie Bodinier / Robin Korte / Julia Bräcker / Jens Brockmeyer / Rie Satoh / Reiko Teshima / Angelika Tscheppe / Dieter Palmberger / Reingard Grabherr / Marianne Raith / Linda Sonnleitner / Doris Zach / Konrad Woroszylo / Margit Focke-Tejkl / Herbert Wank / Thorsten Graf / Annette Kuehn / Ines Swoboda / Sara Huber / Fabienne Gay-Crosier / Dominika Polak / Birgit Nagl / Claudia Kitzmüller / Nazanin Samadi / Rene Geyeregger / Beatrice Jahn-Schmid / Ariel Gomez / Jaana Haka / Liisa Hattara / Marika Heikkinen / Merja H Niemi / Juha Rouvinen / Petri Saviranta / Pekka Mattila / Kristiina Takkinen / Marja-Leena Laukkanen / Isabel Pablos / Bianca Kastner / Mira Silar / Julij Selb / Rok Kogovsek / Mitja Kosnik / Peter Korosec / Leticia Pestana / Alcinda Campos Melo / Ana Mendes / Maria Elisa Pedro / Maria Conceição Pereira Santos / Françoise Bienvenu / Claire Goursaud / Lorna Garnier / Sandrine Jacquenet / Michaël Degaud / Sébastien Viel / Annick Barre / Pierre Rougé / Jacques Bienvenu / Joana Vitte / Amel Bensalah / Isabelle Cleach / Laurent Mousseau / Chantal Agabriel / Valérie Liabeuf / Joëlle Birnbaum / Jean-Louis Mège / James Gardner / Minal Gandhi / Harsha Kariyawasam / Giuseppina Rotiroti / Frederico Regateiro / Emília Faria / Johannes Martin Schmid / Ronald Dahl / Hans Juergen Hoffmann / Letícia Pestana / Diana Silva / Teresa Vieira / Ana Maria Pereira / André Moreira / Luís Delgado / Sara Prates / Cátia Alves / Elena Finelli / Paula Leiria Pinto / Bárbara Kong Cardoso / Cíntia Cruz / Filipa Semedo / Elza Tomaz / Filipe Inácio / Santanu Maity / Ivona Baricevic-Jones / Justin T. Marsh / Phil E. Johnson / Anuradha Balasundaram / Anya-May Hope / Aafke Taekema / Angela Simpson / Aida Semic-Jusufagic / E. N. Clare Mills / Gourdon Dubois Nelly / Sellam Laetitia / Pereira Bruno / Michaud Elodie / Messaoudi Khaled / Evrard Bertrand / Fauquert Jean-Luc / Richard E. Goodman / Elena Rodríguez Plata / Luis Amaral / Borja Bartolomé / Alice Coimbra / Jose L Placido / Carmen Saviana Ganea / Carol Ann Costello / Martin Sorensen / Clare Mills / Adrian Rogers / Aage Otherhals / Tanja Kalic / Isabella Ellinger / Eva Waltl / Verena Niederberger-Leppin / Dawid Szczepankiewicz / Ewa Pruszynska-Oszmalek / Marek Skrzypski / Krzysztof W. Nowak / Aleksandra Szczepankiewicz / Gwang-Cheon Jang / Iva Markovic / Andreas Borowski / Tina Vetter / Andreas Wohlmann / Michael Kuepper / Karlheinz Friedrich / Ibon Eguiluz Gracia / Anthony Bosco / Ralph Dollner / Guro Reinholt Melum / Anya C Jones / Maria Lexberg / Patrick G Holt / Espen Sønderaal Bækkevold / Frode Lars Jahnsen / Paulina Sobkowiak / Marta Rachel / Beata Narozna / Dorota Jenerowicz / Witold Swiatowy / Anna Breborowicz / Reinhard Nestelbacher / Hiroyuki Fukui

    Clinical and Translational Allergy, Vol 6, Iss S2, Pp 1-

    2016  Volume 34

    Abstract: Table of contents ORAL ABSTRACTS Symposium 1: Biochemistry, structure and environment of the allergen: what makes a protein an allergen? O1 Two cell-membrane peptidases carrying galactose-alpha-1,3-galactose are implicated in delayed anaphylactic ... ...

    Abstract Table of contents ORAL ABSTRACTS Symposium 1: Biochemistry, structure and environment of the allergen: what makes a protein an allergen? O1 Two cell-membrane peptidases carrying galactose-alpha-1,3-galactose are implicated in delayed anaphylactic reactions upon pork kidney ingestion in patients with IgE-antibodies to alpha-Gal Christiane Hilger, Kyra Swiontek, Jörg Fischer, François Hentges, Christiane Lehners, Martine Morisset, Bernadette Eberlein, Tilo Biedermann, Markus Ollert O2 Structure solution of Pla l 1 suggests similar folding of Ole e 1-like family members but distinct immunological properties Sabrina Wildner, Teresa Stemeseder, Regina Freier, Peter Briza, Roland Lang, Eva Batanero, Mayte Villalba, Jonas Lidholm, Thomas Hawranek, Fatima Ferreira, Hans Brandstetter, Gabriele Gadermaier Symposium 2: New allergen molecules in the spotlight O3 Identification of the cysteine protease Amb a 11 as a novel major allergen from short ragweed (Ambrosia artemisiifolia) Philippe Moingeon, Rachel Groeme, Julien Bouley, Véronique Bordas, Maxime Le Mignon, Laetitia Bussières, Aurélie Lautrette, Laurent Mascarell, Vincent Lombardi, Véronique Baron-Bodo, Henri Chabre, Thierry Batard, Emmanuel Nony O4 Production and characterization of polybia paulista recombinant antigen 5: a valuable diagnostic tool Karine Marafigo De Amicis, Alexandra Sayuri Watanabe, Daniele Danella Figo, José Roberto Aparecido Dos Santos-Pinto, Mario Sergio Palma, Fabio Fernandes Morato Castro, Jorge Kalil, Therese Wohlschlager, Peter Briza, Sabrina Wildner, Fatima Ferreira-Briza, Gabriele Gadermaier, Keity Souza Santos Symposium 3: Progress in molecular and cellular diagnosis O5 Basophil activation test with recombinant Pru p 3; identifying genuine peach allergic patients Margaretha Faber, Athina Van Gasse, Vito Sabato, Margo M. Hagendorens, Chris H. Bridts, Luc S. De Clerck, Araceli Diaz Perales, Didier Ebo O6 Nanofluidic technology enables rapid, near-patient quantification of allergen-specific IgE Petra Zavadakova, Aurélie Buchwalder, Fabien Rebeaud, Iwan Märki Symposium 4: Relevance of molecular diagnostics for intervention and treatment O7 Longitudinal analysis of Bet v 1-specific epitope repertoires during birch pollen immunotherapy Barbara Gepp, Nina Lengger, Christian Möbs, Wolfgang Pfützner, Christian Radauer, Barbara Bohle O8 A natural CCD-free tool: is polistes sp. venom suitable for polybia paulista diagnosis and therapy? Karine Marafigo De Amicis, Alexandra Sayuri Watanabe, Clovis Eduardo Galvao, Daniele Danella Figo, Jose Roberto Aparecido Santos-Pinto, Mario Sergio Palma, Fabio Fernandes Morato Castro, Jorge Kalil, Fatima Ferreira, Gabriele Gadermaier, Keity Souza Santos Symposium 5: The advent of molecular allergology in epidemiology O9 Peanut oleosins: from identification to diagnostic testing Christian Schwager, Skadi Kull, Frauke Schocker, Jochen Behrends, Wolf-Meinhard Becker, Uta Jappe O10 Endotypes of oral allergy syndrome in childhood: a molecular diagnostic approach Carla Mastrorilli, Salvatore Tripodi, Carlo Caffarelli, Riccardo Asero, Arianna Dondi, Giampaolo Ricci, Carlotta Povesi Dascola, Elisabetta Calamelli, Andrea Di Rienzo Businco, Annamaria Bianchi, Tullio Frediani, Carmen Verga, Iride Dello Iacono, Diego Peroni, Giuseppe Pingitore, Roberto Bernardini, Paolo Maria Matricardi Symposium 6: Molecular AIT: which approaches will make it to market? O11 Mbc4: an innovative molecule to tackle birch pollen and concomitant food allergies Heidi Hofer, Claudia Asam, Michael Hauser, Peter Briza, Martin Himly, Christof Ebner, Fatima Ferreira O12 Challenges and solutions associated with the production of recombinant Bet v 1 allergen as a therapeutic protein Emmanuel Nony, Maxime Le Mignon, Pierrick Lemoine, Karine Jain, Kathy Abiteboul, Monica Arvidsson, Sabina Rak, Philippe Moingeon Clinical Cases: Breakthroughs and headaches from CRD: interactive session CC1 Anaphylaxis caused by lipid transfer proteins: a complex clinical pattern syndrome Inês Mota, Filipe Benito Garcia, Angela Gaspar, Cristina Arêde, Susana Piedade, Graça Sampaio, Graça Pires, Luís Miguel Borrego, Cristina Santa-Marta, Mário Morais-Almeida CC2 IgE sensitization profile in a patient with asteraceae pollen-exotic fruits association Florin-Dan Popescu, Mariana Vieru, Florin-Adrian Secureanu CC3 Food-dependent: exercise induced anaphylaxis. Which component to blame? Rosa Anita Rodrigues Fernandes, Isabel Carrapatoso, Raquel Gomes, Celso Pereira, Ana Todo-Bom CC4 Anaphylaxis to intravenous iron preparations in a patient that tolerates oral administration María Cecilia Martín Fernández De Basoa, Javier Barrios Regio, Juan De Castro Cordova, Antón Fernández Ferreiro CC5 IgE sensitization pattern in an adult patient with oral allergy syndrome to peanuts and pollinosis from southern Romania Florin-Dan Popescu, Mariana Vieru, Florin-Adrian Secureanu CC6 Evidence of specific IgE to plant-derived cross-reactive carbohydrate determinant in a patient with delayed anaphylaxis to red meat Mariana Vieru, Florin-Dan Popescu, Florin-Adrian Secureanu POSTER PRESENTATIONS Poster Session 1: Molecular allergology and epidemiology P1 Atopic children produce stronger and more frequent IgG responses than non-atopic children: longitudinal data from the German MAS birth cohort Olympia Tsilochristou, Serena Perna, Alina Schwarz, Alexander Rohrbach, Antonio Cappella, Laura Hatzler, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Antje Schuster, Raffael D’amelio, Ulrich Wahn, Thomas Keil, Susanne Lau, Paolo Maria Matricardi P2 The IgG sensitization profiles against 112 allergenic components support the absence of a protective role of IgG in allergic individuals, outside of the context of SIT Pol André Apoil, Claire Mailhol, Anne Broué-Chabbert, Agnès Juchet, Alain Didier, Elodie Carrer, Thomas Lanot, Antoine Blancher P3 The immune response against the timothy grass pollen allergen Phl p 5 in non-allergic humans Almedina Kurtaj, Christoph Hillebrand, Gerda Fichtinger, Martin Danzer, Christian Gabriel, Theresa Thalhamer, Sandra Scheiblhofer, Josef Thalhamer, Richard Weiss P4 Analyzing the cross-reactivity profile of the major ragweed allergen Amb a 1 Martin Wolf, Michael Hauser, Ulrike Pichler, Teresa Twaroch, Gabriele Gadermaier, Christof Ebner, Hidenori Yokoi, Toshiro Takai, Alain Didierlaurent, Adriano Mari, Peter Briza, Heidrun Behrendt, Angela Neubauer, Frank Stolz, Fátima Ferreira, Michael Wallner P5 LTP (Pru p 3) sensitisation in skin prick test: which means in clinical practice? Sara Carvalho, Tatiana Lourenço, Joana Cosme, Fátima Cabral Duarte, Amélia Spínola Santos, Ana Célia Costa, Manuel Pereira Barbosa P6 IgE profiles, allergen exposure and lifestyle of 501 Austrian pupils: investigation of influences on the development of allergic sensitizations Teresa Stemeseder, Eva Klinglmayr, Bettina Schweidler, Lisa Lueftenegger, Stephanie Moser, Patrick Doppler, Roland Lang, Martin Himly, Gertie J. Oostingh, Arne Bathke, Joerg Zumbach, Thomas Hawranek, Gabriele Gadermaier P7 Molecular profiles of sensitization to perennial inhalant allergens in a middle European region Petr Panzner, Martina Vachova, Tomas Vlas, Marek Maly P8 Evolution of the IgE response to house dust mite allergen molecules in childhood Daniela Posa, Serena Perna, Stephanie Hofmaier, Laura Hatzler, Alexander Rohrbach, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Antje Schuster, Philippe Stock, Ulrich Wahn, Linus Grabenhenrich, Thomas Keil, Susanne Lau, Kuan-Wei Chen, Yvonne Resch, Susanne Vrtala, Rudolf Valenta, Paolo Maria Matricardi P9 Tropomyosin (Pen a1): to include or not to include in skin prick testing? Joana Cosme, Sara Carvalho, Tatiana Lourenço, Amélia Spínola Santos, Manuel Pereira Barbosa Immunoallergy Department - Hospital de Santa Maria – Centro Hospitalar Lisboa Norte, Lisbon, Portugal, Lisbon, Portugal; Immunoallergy Department - Hospital de Santa Maria – Centro Hospitalar Lisboa Norte, Lisbon, Portugal; Faculdade de Medicina de Lisboa, Lisbon, Portugal P10 Component-resolved IgE profiles in Georgian patients Tamar Abramidze, Nino Lomidze, Maia Gotua P11 Cross reactivity between food and pollen allergens in Lithuania according to spIgE evaluation Austeja Dapkeviciute, Ruta Einikyte, Jolita Norkuniene, Laima Skrickiene, Asta Miskiniene, Violeta Kvedariene P12 Distribution of inhalant allergy in the population of Lithuania Ruta Einikyte, Austeja Dapkeviciute, Jolita Norkuniene, Laima Skrickiene, Asta Miskiniene, Violeta Kvedariene Poster Session 2: Allergen molecules: identification, characterization, structure and function P13 Interference of antigen 5-based cross-reactivity in the diagnosis of hymenoptera venom allergy Maximilian Schiener, Bernadette Eberlein, Carmen Moreno-Aguilar, Gunilla Pietsch, Mareike Mc Intyre, Lea Schwarze, Dennis Rußkamp, Tilo Biedermann, Edzard Spillner, Ulf Darsow, Carsten Schmidt-Weber, Markus Ollert, Simon Blank P14 IgE cross-reactivity between European Hymenoptera and Asian hornet (Vespa velutina) venom allergens Cyril Longé, Andrea Brazdova, Jean-Louis Brunet, Claire Schwartz, Bruno Girodet, François Lavaud, Joelle Birnbaum, Nhân Pham Thi, Magalie Duchateau, Julia Chamot-Rooke, Laurence Guilloux, Marie-Ange Selva, Rémy Couderc, Hélène Sénéchal, Jean-Pierre Sutra, Pascal Poncet P15 Carbohydrate composition of house dust mite extracts and major group 1 and group 2 allergens Steffen Augustin, Linda Pump, Martin Wald, Thomas Eichhorn, Frank Fischer, Christoph Willers P16 Specificity of monoclonal antibodies against cross-reactive carbohydrate determinants Michaela Miehe, Melanie Plum, Sara Wolf, Frederic Jabs, Tim Raiber, Frank Bantleon, Henning Seismann, Thilo Jakob, Edzard Spillner P17 Red meat allergic patients have a selective IgE response to the a-Gal glycan Danijela Apostolovic, Anh Thu Tran, Sara Sanchez-Vidaurre, Tanja Cirkovic Velickovic, Maria Starkhammar, Carl Hamsten, Marianne Van Hage P18 Specificity of non-specific lipid transfer proteins and influence of the ligands on their three-dimensional structure Pawel Dubiela, Piotr Humeniuk, Sabine Pfeifer, Merima Bublin, Tomasz Borowski, Karin Hoffmann-Sommergruber P19 Real-time PCR analysis of Pru av 1 and Pru av 3 allergens Martie C.M. Verschuren, Shanna Bastiaan-Net, Defien Depoortere, Kay Foetisch, Stephan Scheurer, Harry J Wichers, Theo Noij P20 Specificity of anti-Pru av 1 antibodies for the detection of Pru av 1 isoallergens Martie C.M. Verschuren, Shanna Bastiaan-Net, Nikki M.E. Van Uden, Karel Vandenberghe, Kay Foetisch, Stephan Scheurer, Harry J. Wichers H.J., Theo H.M. Noij P21 Enhancing recombinant production yield of Bet v 1 through codon usage harmonization Anargyros Roulias, Maria Alejandra Parigiani, Heidi Hofer, Claudia Asam, Christof Ebner, Fátima Ferreira P22 Structural and dynamic insights into the world of PR-10 allergens Linda Ahammer, Sarina Grutsch, Martin Tollinger Poster Session 3: Allergen molecules: identification, characterization, structure and function P23 Purification of polcalcin from different pollen allergenic sources by antibody-affinity chromatography Raquel Moya, Mª Angeles López-Matas, Raquel Reyes, Jerónimo Carnés P24 Variations of wheat allergens in cultivars measured through a targeted quantitative mass spectrometry approach Colette Larré, Hélène Rogniaux, Roberta Lupi, Sandra Denery-Papini P25 Art v 1, Amb a 4 and Par h 1 defensin-like proteins share similar structural features but distinct immunological and allergenic properties Isabel Maria Pablos, Stephanie Eichhorn, Yoan Machado, Peter Briza, Christof Ebner, Jung-Won Park, Alain Didierlaurent, Naveen Arora, Stefan Vieths, Gabriele Gadermaier, Fatima Ferreira P26 Homogeneity or diversity of IgE-binding proteins in wheat dependant exercise induced anaphylaxis? Sandra Denery-Papini, Charlene Tanaka, Florence Pineau, Roberta Lupi, Martine Drouet, Etienne Beaudouin, Martine Morisset, Susan Altenbach P27 Deciphering the role of disulfide bonds and of repetitive epitopes in immunoglobulin E binding to wheat gliadins Sandra Denery-Papini, Hamza Mameri, Chantal Brossard, Roberta Lupi, Florence Pineau, Jean Charles Gaudin, Denise Anne Moneret-Vautrin, Etienne Beaudouin, Evelyne Paty, Martine Drouet, Olivier Tranquet, Colette Larré P28 Assessment of the allergenicity of soluble fractions from bread and durum wheats genotypes Roberta Lupi, Stefania Masci, Olivier Tranquet, Denise-Anne Moneret-Vautrin, Sandra Denery-Papini, Colette Larré P29 Isolation and characterization of Ara h 12 and Ara h 13: defensins, a novel class of peanut allergens Skadi Kull, Arnd Petersen, Marisa Böttger, Sandra Rennert, Wolf-Meinhard Becker, Susanne Krause, Martin Ernst, Thomas Gutsmann, Johann Bauer, Buko Lindner, Uta Jappe P30 Allergenicity attributes of different peanut market types Stef Koppelman, Shyamali Jayasena, Dion Luykx, Erik Schepens, Danijela Apostolovic, Govardus De Jong, Tom Isleib, Julie Nordlee, Joe Baumert, Steve Taylor, Soheila Maleki P31 The impact of peanut lipids on Ara h 1-induced immune responses in monocytes-derived dendritic cells Chiara Palladino, Barbara Gepp, Sofía Sirvent, Alba Angelina, Merima Bublin, Christian Radauer, Nina Lengger, Thomas Eiwegger, Oscar Palomares, Heimo Breiteneder P32 Compared allergenicity of native and thermally aggregated ovalbumin as large agglomerated particles Mathilde Claude, Roberta Lupi, Grégory Bouchaud, Marie Bodinier, Chantal Brossard, Sandra Denery-Papini P33 Simulation of the gastrointestinal digestion of the hazelnut allergens Cor a 9 and Cor a 11 by an in-vitro model and characterisation of peptidic products including epitopes by HPLC-MS/MS Robin Korte, Julia Bräcker, Jens Brockmeyer P34 Analysis of distribution of rice allergens in brown rice grain and allergenicity of the products containing rice bran Rie Satoh, Reiko Teshima Poster Session 4: Molecular approaches in AIT P35 Production of a recombinant hypoallergenic variant of the major peanut allergen Ara h 2 for allergen-specific immunotherapy Angelika Tscheppe, Dieter Palmberger, Merima Bublin, Christian Radauer, Chiara Palladino, Barbara Gepp, Nina Lengger, Reingard Grabherr, Heimo Breiteneder P36 Mutagenesis of amino acids critical for calcium-binding leads to the generation of a hypoallergenic Phl p 7 variant Marianne Raith, Linda Sonnleitner, Doris Zach, Konrad Woroszylo, Margit Focke-Tejkl, Herbert Wank, Thorsten Graf, Annette Kuehn, Ines Swoboda P37 Are birch pollen allergen immunotherapy induced blocking antibodies protective for cross-reactive allergens? Claudia Asam, Sara Huber, Heidi Hofer, Roland Lang, Thomas Hawranek, Fátima Ferreira, Michael Wallner P38 High success of 58 subcutaneous immunotherapy for pets allergy in a polyallergic cohort of patients: a component resolved individually adapted treatment (CRIAT) Fabienne Gay-Crosier P39 Neutrophils are potential antigen presenting cells in IgE- mediated allergy Dominika Polak, Birgit Nagl, Claudia Kitzmüller, Barbara Bohle P40 Characterization of allergen-specific CD8+ T cells in type I allergy Nazanin Samadi, Claudia Kitzmüller, Rene Geyeregger, Barbara Bohle, Beatrice Jahn-Schmid Poster Session 5: Molecular and cellular diagnostic tests P41 Nanofluidic-based biosensors allow quantification of total circulating IgE from a drop of blood in 5 minutes Aurélie Buchwalder, Ariel Gomez, Fabien Rebeaud, Iwan Märki P42 Allergen microarray for the analysis of serum IgE binding profile and allergenic activity Jaana Haka, Liisa Hattara, Marika Heikkinen, Merja H Niemi, Juha Rouvinen, Petri Saviranta, Pekka Mattila, Kristiina Takkinen, Marja-Leena Laukkanen P43 Generation of a well-characterized panel of periplaneta americana allergens for component resolved diagnosis Stephanie Eichhorn, Isabel Pablos, Bianca Kastner, Bettina Schweidler, Sabrina Wildner, Peter Briza, Jung-Won Park, Naveen Arora, Stefan Vieths, Gabriele Gadermaier, Fatima Ferreira P44 Improved diagnostic sensitivity of recombinant Api m 1 and Ves v 5 in diagnosis of Hymenoptera venom allergy Mira Silar, Julij Selb, Rok Kogovsek, Mitja Kosnik, Peter Korosec P45 Added value of biomarkers of primary sensitization and cross-reactivity in patients with hymenoptera venom allergy Leticia Pestana, Alcinda Campos Melo, Ana Mendes, Maria Elisa Pedro, Manuel Pereira Barbosa, Maria Conceição Pereira Santos P46 Cosensitization to Alt a 1 and Act d 2: more than a fortuitous association? Françoise Bienvenu, Claire Goursaud, Lorna Garnier, Sandrine Jacquenet, Michaël Degaud, Sébastien Viel, Annick Barre, Pierre Rougé, Jacques Bienvenu, Joana Vitte P47 Molecular diagnosis for peanut allergy: ALFA method performs as well as established methods for Ara h 1, Ara h 2, Ara h 6, Ara h 9 and CCD Amel Bensalah, Isabelle Cleach, Laurent Mousseau, Chantal Agabriel, Valérie Liabeuf, Joëlle Birnbaum, Jean-Louis Mège, Joana Vitte P48 Evaluation of a food challenge service in relation to specific IgE to molecular components in children with suspected peanut allergy James Gardner, Minal Gandhi, Harsha Kariyawasam, Giuseppina Rotiroti P49 Component resolved diagnosis in cereal allergy Isabel Carrapatoso, Celso Pereira, Frederico Regateiro, Emília Faria, Ana Todo-Bom Poster Session 6: Molecular diagnosis in prevention and therapy P50 Pretreatment molecular sensitizations determine the sIgG4 induction during the updosing of SCIT and may be useful to identify clinically relevant additional sensitizations Johannes Martin Schmid, Ronald Dahl, Hans Juergen Hoffmann P51 Usefulness of recombinant latex allergens in immunotherapy’s decision and follow-up Inês Mota, Filipe Benito Garcia, Angela Gaspar, Mário Morais-Almeida P52 Omega-5-gliadin in the diagnosis of wheat-dependent anaphylaxis induced by ibuprofen but not by exercise Joana Cosme, Letícia Pestana, Amélia Spínola Santos, Manuel Pereira Barbosa P53 Food dependent exercise-induced anaphylaxis: a component-resolved and in vitro depletion approach to access IgE cross-reactivity Diana Silva, Teresa Vieira, Ana Maria Pereira, André Moreira, Luís Delgado P54 Olive pollen allergens: what are we missing? Sara Prates, Cátia Alves, Elena Finelli, Paula Leiria Pinto P55 Purified Alt a 1 extract in Alternaria alternata allergy diagnosis Bárbara Kong Cardoso, Cíntia Cruz, Filipa Semedo, Elza Tomaz, Filipe Inácio P56 Use of specific IgE Bos d8 (casein) to aid early introduction of dietary baked milk in children with cows’ milk allergy James Gardner, Santanu Maity, Giuseppina Rotiroti, Minal Gandhi P57 Molecular characterisation and immunoreactivity of a peanut ingredient for use in oral food challenges Ivona Baricevic-Jones, Justin T. Marsh, Phil E. Johnson, Anuradha Balasundaram, Anya-May Hope, Aafke Taekema, Angela Simpson, Aida Semic-Jusufagic, E.N. Clare Mills P58 Specific IgE to recombinant allergens of hazelnut and oral food challenge in children Gourdon Dubois Nelly, Sellam Laetitia, Pereira Bruno, Michaud Elodie, Messaoudi Khaled, Evrard Bertrand, Fauquert Jean-Luc Poster session 7/8: miscellaneous P59 What defines a protein as an allergen? A discussion of sources and sufficiency Richard E. Goodman P60 Cat allergy: relationship between clinical and molecular diagnostic María Cecilia Martín Fernández De Basoa, Antón Fernández Ferreiro, Elena Rodríguez Plata P61 Anaphylaxis to rabbit: the cat came in last Luis Amaral, Borja Bartolomé, Alice Coimbra, Jose L Placido P62 Dog allergy: relationship between clinical and molecular diagnostic María Cecilia Martín Fernández De Basoa, Antón Fernández Ferreiro, Elena Rodríguez Plata P63 Correlation of serum timothy grass-pollen specific IgE levels determined by two immunoblot test systems Mariana Vieru, Florin-Dan Popescu, Florin-Adrian Secureanu, Carmen Saviana Ganea P64 Development of oral food challenge formulations for diagnosis of fish allergy using powdered fish ingredients Carol Ann Costello, Ivona Baricevic-Jones, Martin Sorensen, Clare Mills, Adrian Rogers, Aage Otherhals P65 Fish and peanut allergens interact with plasma membranes of intestinal and bronchial epithelial cells and induce differential gene expression of cytokines and chemokines Tanja Kalic, Isabella Ellinger, Chiara Palladino, Barbara Gepp, Eva Waltl, Verena Niederberger-Leppin, Heimo Breiteneder P66 Interleukin 4 affects fat tissue metabolism and expression of pro-inflammatory factors in isolated rat adipocytes Dawid Szczepankiewicz, Ewa Pruszynska-Oszmalek, Marek Skrzypski, Krzysztof W. Nowak, Aleksandra Szczepankiewicz P67 Ozone induced airway hyperreactivity in PD-L2−/− mice model Gwang-Cheon Jang P68 Thymic stromal lymphopoietin (TSLP) and its receptor as targets for the development of anti-inflammatory inhibitory agents Iva Markovic, Andreas Borowski, Tina Vetter, Andreas Wohlmann, Michael Kuepper, Karlheinz Friedrich P69 The mononuclear phagocyte system in experimentally-induced allergic rhinitis Ibon Eguiluz Gracia, Anthony Bosco, Ralph Dollner, Guro Reinholt Melum, Anya C Jones, Maria Lexberg, Patrick G Holt, Espen Sønderaal Bækkevold, Frode Lars Jahnsen P70 Expression of histamine metabolizing enzymes is increased in allergic children Aleksandra Szczepankiewicz, Paulina Sobkowiak, Marta Rachel, Beata Narozna, Dorota Jenerowicz, Witold Swiatowy, Anna Breborowicz P71 Modifying the glycosylation of human IgE towards oligomannosidic structures does not affect its biological activity Melanie Plum, Sara Wolf, Frank Bantleon, Henning Seismann, Frederic Jabs, Michaela Miehe, Thilo Jakob, Edzard Spillner P72 Flying Labs: an educational initiative to transfer allergy research into high-school settings Michael Wallner, Heidi Hofer, Fatima Ferreira, Reinhard Nestelbacher P73 Clinical significance of antihistamines and Kujin, an anti-allergic Kampo medicine Hiroyuki Fukui
    Keywords Immunologic diseases. Allergy ; RC581-607 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2016-10-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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