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  1. AU="Casadei-Gardini, Andrea"
  2. AU="Wagnon, Jacy"
  3. AU="Eduardo Vicuña"
  4. AU="Li, Chun-Xia"
  5. AU="Pablos-Buitrón, Eva"
  6. AU="Tatum, Megan"
  7. AU="Eric S. Rothstein"
  8. AU="Zheng, Ru-Nan"
  9. AU="Lucia Araujo-Chaveron"
  10. AU=Wong D H T AU=Wong D H T
  11. AU="Yassin, Heba A"
  12. AU="Blight, Colin R"
  13. AU="Tang, Jack"
  14. AU="Michael E. Dorcas"
  15. AU="Oliveira, Fernando Rocha de"
  16. AU="Rossmanith, R."
  17. AU="Xi He"
  18. AU="Somenath Mitra"
  19. AU=Zhao Limei AU=Zhao Limei
  20. AU="Feng, Sheau-Line"
  21. AU="Goldman, Nick"
  22. AU="Oumezzine, Ma"
  23. AU="Elena D. Nosyreva"
  24. AU="Birara, Sunita"
  25. AU=Banegas Matthew P. AU=Banegas Matthew P.
  26. AU="Mendelow, Alexander David"
  27. AU="Pereira, Taci"
  28. AU="Natalie Taylor"
  29. AU="Moradi, Tayebeh"
  30. AU="Ramesh C. Santra"
  31. AU="Selvarajah, Aravinda"
  32. AU="Vaisman, Adva"
  33. AU="Rádiková, Žofia"
  34. AU=Poulin Stphane P.

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  1. Artikel ; Online: Liver resection for HCC in patients with metabolic syndrome: questions answered, questions raised.

    Cucchetti, Alessandro / Casadei-Gardini, Andrea

    Hepatology (Baltimore, Md.)

    2023  Band 77, Heft 5, Seite(n) 1463–1464

    Mesh-Begriff(e) Humans ; Carcinoma, Hepatocellular/surgery ; Liver Neoplasms/surgery ; Metabolic Syndrome/complications ; Metabolic Syndrome/surgery ; Hepatectomy ; Retrospective Studies
    Sprache Englisch
    Erscheinungsdatum 2023-01-03
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1097/HEP.0000000000000034
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: More than shots in the dark: improving patient stratification to move closer to personalised therapies in intrahepatic cholangiocarcinoma.

    Arechederra, Maria / Casadei Gardini, Andrea / Raggi, Chiara

    Gut

    2024  Band 73, Heft 3, Seite(n) 389–390

    Mesh-Begriff(e) Humans ; Cholangiocarcinoma/therapy ; Cholangiocarcinoma/pathology ; Bile Ducts, Intrahepatic/pathology ; Bile Duct Neoplasms/therapy ; Bile Duct Neoplasms/pathology
    Sprache Englisch
    Erscheinungsdatum 2024-02-23
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2023-331119
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Response to letter entitled Re: Sequential therapies after atezolizumab plus bevacizumab or lenvatinib first-line treatments in hepatocellular carcinoma patients.

    Persano, Mara / Rimini, Margherita / Casadei Gardini, Andrea

    European journal of cancer (Oxford, England : 1990)

    2023  Band 192, Seite(n) 113264

    Mesh-Begriff(e) Humans ; Bevacizumab/adverse effects ; Carcinoma, Hepatocellular/drug therapy ; Liver Neoplasms/drug therapy
    Chemische Substanzen atezolizumab (52CMI0WC3Y) ; Bevacizumab (2S9ZZM9Q9V) ; lenvatinib (EE083865G2)
    Sprache Englisch
    Erscheinungsdatum 2023-08-22
    Erscheinungsland England
    Dokumenttyp Letter ; Comment
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/j.ejca.2023.113264
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Angiogenesis in biliary tract cancer: targeting and therapeutic potential.

    Rimini, Margherita / Casadei-Gardini, Andrea

    Expert opinion on investigational drugs

    2021  Band 30, Heft 4, Seite(n) 411–418

    Abstract: ... ...

    Abstract Introduction
    Mesh-Begriff(e) Angiogenesis Inhibitors/administration & dosage ; Angiogenesis Inhibitors/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Biliary Tract Neoplasms/blood supply ; Biliary Tract Neoplasms/drug therapy ; Humans ; Immune Checkpoint Inhibitors/administration & dosage ; Molecular Targeted Therapy ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/pathology ; Patient Selection ; Prognosis ; Tumor Microenvironment
    Chemische Substanzen Angiogenesis Inhibitors ; Immune Checkpoint Inhibitors
    Sprache Englisch
    Erscheinungsdatum 2021-03-28
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1182884-5
    ISSN 1744-7658 ; 0967-8298 ; 1354-3784
    ISSN (online) 1744-7658
    ISSN 0967-8298 ; 1354-3784
    DOI 10.1080/13543784.2021.1881479
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Understanding surrogate measures of overall survival after trans-arterial chemoembolization of hepatocellular carcinoma.

    Cucchetti, Alessandro / Casadei Gardini, Andrea

    Liver international : official journal of the International Association for the Study of the Liver

    2021  Band 41, Heft 5, Seite(n) 891–893

    Mesh-Begriff(e) Carcinoma, Hepatocellular/surgery ; Chemoembolization, Therapeutic ; Hepatectomy ; Humans ; Liver Neoplasms/surgery
    Sprache Englisch
    Erscheinungsdatum 2021-04-13
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.14873
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Understanding the causes of recurrent HCC after liver resection and radiofrequency ablation.

    Bosi, Carlo / Rimini, Margherita / Casadei-Gardini, Andrea / Giorgio Ercolani

    Expert review of anticancer therapy

    2023  Band 23, Heft 5, Seite(n) 503–515

    Abstract: Introduction: Surgical resection and radiofrequency ablation are preferred options for early-stage disease. With the increasing availability of therapeutic options understanding the causes of recurrence and identifying its predictors should be ... ...

    Abstract Introduction: Surgical resection and radiofrequency ablation are preferred options for early-stage disease. With the increasing availability of therapeutic options understanding the causes of recurrence and identifying its predictors should be priorities in the hepatocellular carcinoma (HCC) research agenda.
    Areas covered: Current knowledge of HCC predictors of recurrence is reviewed, and recent insights about their underlying mechanisms are presented. In addition, results from recent clinical trials investigating treatment combinations are critically appraised.
    Expert opinion: HCC recurrence is either due to the progressive growth of microscopic residual disease or to de novo cancer development in the context of a diseased liver, each occurring in an early (<2 years) vs. late (≥2 years) fashion. Collectively, morphological, proteomic, and transcriptomic data suggest vascular invasion and angiogenesis as key drivers of HCC recurrence. Agents aimed at blocking either of these two hallmarks should be prioritized at the moment of early-stage HCC clinical trial design. Emerging results from clinical trials testing ICI in early-stage HCC underscore the importance of defining the best treatment sequence and the most appropriate combination strategies.Finally,as different responses to systemic therapies are increasingly defined according to the HCC etiology, patient enrollment into clinical trials should take into account the biological characteristics of their inherent disease.
    Mesh-Begriff(e) Humans ; Carcinoma, Hepatocellular/therapy ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/therapy ; Liver Neoplasms/pathology ; Proteomics ; Radiofrequency Ablation ; Chemoembolization, Therapeutic ; Catheter Ablation/adverse effects ; Treatment Outcome ; Retrospective Studies ; Neoplasm Recurrence, Local/therapy
    Sprache Englisch
    Erscheinungsdatum 2023-04-20
    Erscheinungsland England
    Dokumenttyp Review ; Journal Article
    ZDB-ID 2112544-2
    ISSN 1744-8328 ; 1473-7140
    ISSN (online) 1744-8328
    ISSN 1473-7140
    DOI 10.1080/14737140.2023.2203387
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Why does survival of hepatocellular carcinoma patients remain so low? Key stumbling blocks and questions in preclinical and clinical development.

    Rimini, Margherita / Liscia, Nicole / Burgio, Valentina / Casadei-Gardini, Andrea

    Expert opinion on investigational drugs

    2022  Band 31, Heft 5, Seite(n) 483–494

    Abstract: Introduction: Hepatocellular carcinoma (HCC) is a complex disease, which involves diverse molecular pathways and etiologies. In recent years, several new systemic treatments have improved survival in advanced stage disease, but numerous significant ... ...

    Abstract Introduction: Hepatocellular carcinoma (HCC) is a complex disease, which involves diverse molecular pathways and etiologies. In recent years, several new systemic treatments have improved survival in advanced stage disease, but numerous significant challenges remain. No significant improvements have been achieved in the intermediate stage disease; this may be attributed to the difficulties in stratification of patients and the broad spectrum of clinical situations in terms of tumor burden and liver function.
    Areas covered: This article considers the recent progress in first- and second-line therapy for advanced HCC. Investigational strategies conducted in intermediate stage HCC, which involve mainly combination therapy with locoregional approaches, and systemic drugs, antiangiogenics, immunotherapies (or both) are then examined. Later, the paper offers insights on the questions and challenges that lie ahead for treating HCC.
    Expert opinion: Clinical and biomolecular markers for the stratification of patients are needed for therapeutic progress. Further molecular profiling data could enhance our knowledge of the molecular pathways underlying this tumor and facilitate the identification of targetable aberrations. This could offer opportunities for precision medicine approaches and improved survival.
    Mesh-Begriff(e) Angiogenesis Inhibitors/therapeutic use ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/therapy ; Combined Modality Therapy ; Humans ; Immunotherapy ; Liver Neoplasms/pathology
    Chemische Substanzen Angiogenesis Inhibitors
    Sprache Englisch
    Erscheinungsdatum 2022-03-16
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1182884-5
    ISSN 1744-7658 ; 0967-8298 ; 1354-3784
    ISSN (online) 1744-7658
    ISSN 0967-8298 ; 1354-3784
    DOI 10.1080/13543784.2022.2053108
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Incorporating alpha-fetoprotein within dimensional criteria for hepatocellular carcinoma transplantation.

    Cucchetti, Alessandro / Casadei Gardini, Andrea

    Hepatobiliary surgery and nutrition

    2019  Band 8, Heft 1, Seite(n) 65–66

    Sprache Englisch
    Erscheinungsdatum 2019-03-01
    Erscheinungsland China (Republic : 1949- )
    Dokumenttyp Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn.2018.11.02
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Recent Research on Gastrointestinal Carcinoma.

    Rovesti, Giulia / Marisi, Giorgia / Casadei-Gardini, Andrea

    Cancers

    2021  Band 13, Heft 2

    Abstract: This series of 10 articles (eight original articles and two reviews) is presented by international leaders in gastrointestinal cancer research [ ... ]. ...

    Abstract This series of 10 articles (eight original articles and two reviews) is presented by international leaders in gastrointestinal cancer research [...].
    Sprache Englisch
    Erscheinungsdatum 2021-01-18
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13020333
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Sorafenib and metformin: to be, or not to be, that is the question.

    Orsi, Giulia / Casadei-Gardini, Andrea

    Hepatobiliary surgery and nutrition

    2019  Band 8, Heft 4, Seite(n) 411–413

    Sprache Englisch
    Erscheinungsdatum 2019-08-22
    Erscheinungsland China (Republic : 1949- )
    Dokumenttyp Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn.2019.04.01
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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