LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 7 of total 7

Search options

  1. Article ; Online: Design and Optimisation of Sustainable Sample Treatments Based on Ultrasound-Assisted Extraction and Strong Cation-Exchange Purification with Functionalised SBA-15 for Opium Alkaloids in Ground Poppy Seeds.

    Casado-Hidalgo, Gema / Morante-Zarcero, Sonia / Pérez-Quintanilla, Damián / Sierra, Isabel

    Toxins

    2023  Volume 15, Issue 12

    Abstract: An analysis methodology was optimised and validated for the quantification of opium alkaloids (OAs) in ground poppy seeds. This involved ultrasound-assisted extraction (UAE) and solid-phase extraction (SPE) purification before analysis using a high- ... ...

    Abstract An analysis methodology was optimised and validated for the quantification of opium alkaloids (OAs) in ground poppy seeds. This involved ultrasound-assisted extraction (UAE) and solid-phase extraction (SPE) purification before analysis using a high-performance liquid chromatography mass spectrometry detector (HPLC-MS/MS). UAE was optimised through the design of experiments with three factors and a three-level full factorial design. For SPE optimisation, a commercial material was compared with a previously synthesised material of SBA-15 silica functionalised with sulfonic groups (SBA-15-SO
    MeSH term(s) Papaver/chemistry ; Opium ; Tandem Mass Spectrometry/methods ; Morphine ; Silicon Dioxide/chemistry ; Solid Phase Extraction/methods ; Chromatography, High Pressure Liquid/methods
    Chemical Substances Opium (8008-60-4) ; SBA-15 ; Morphine (76I7G6D29C) ; Silicon Dioxide (7631-86-9)
    Language English
    Publishing date 2023-11-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins15120672
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: New Validated Method for the Determination of Six Opium Alkaloids in Poppy Seed-Containing Bakery Products by High-Performance Liquid Chromatography-Tandem Mass Spectrometry after Magnetic Solid-Phase Extraction.

    Casado-Hidalgo, Gema / Martínez-García, Gonzalo / Morante-Zarcero, Sonia / Pérez-Quintanilla, Damián / Sierra, Isabel

    Journal of agricultural and food chemistry

    2022  Volume 70, Issue 24, Page(s) 7594–7606

    Abstract: Bakery products containing poppy seeds are increasingly being commercialized. These seeds may be contaminated with latex from ... ...

    Abstract Bakery products containing poppy seeds are increasingly being commercialized. These seeds may be contaminated with latex from the
    MeSH term(s) Chromatography, High Pressure Liquid/methods ; Ferric Compounds ; Magnetic Phenomena ; Opiate Alkaloids ; Opium/analysis ; Papaver/chemistry ; Seeds/chemistry ; Solid Phase Extraction ; Tandem Mass Spectrometry/methods
    Chemical Substances Ferric Compounds ; Opiate Alkaloids ; Opium (8008-60-4)
    Language English
    Publishing date 2022-06-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.2c01664
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Mesostructured Silica-Coated Magnetic Nanoparticles to Extract Six Opium Alkaloids in Poppy Seeds Prior to Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Analysis

    Casado-Hidalgo, Gema / Pérez-Quintanilla, Damián / Morante-Zarcero, Sonia / Sierra, Isabel

    Foods. 2021 July 08, v. 10, no. 7

    2021  

    Abstract: In recent years, health authorities have become increasingly concerned about preventing consumer exposure to opium alkaloids present in Papaver somniferum L. poppy seeds. In this study, a simple, rapid and efficient method has been optimised to determine ...

    Abstract In recent years, health authorities have become increasingly concerned about preventing consumer exposure to opium alkaloids present in Papaver somniferum L. poppy seeds. In this study, a simple, rapid and efficient method has been optimised to determine all main opioids in poppy seeds (morphine, codeine, thebaine, papaverine, noscapine and oripavine) by UHPLC-QqQ-MS/MS. For this purpose, solid-liquid extraction (SLE) of samples was optimised and six magnetic adsorbent materials with a core of Fe₃O₄ coated with amorphous and mesostructured silica, both functionalised with octadecyl-silane or octyl-silane were characterised and evaluated for magnetic solid-phase extraction (MSPE). The material with the best results was non-functionalised mesostructured silica and, with it, the MSPE procedure was optimised. This method was validated and used to quantify six opioids in 14 edible seed samples (eleven poppy seeds and three seed mixes). Considerable amounts were found (1.5–249.0 mg/kg morphine, <0.2 µg/kg–45.8 mg/kg codeine, <2.4 µg/kg–136.2 mg/kg thebaine, <0.2 µg/kg–27.1 mg/kg papaverine, <0.2 µg/kg–108.7 mg/kg noscapine and <240 µg/kg–33.4 mg/kg oripavine), exceeding maximum limits established in some EU countries and the reference level of morphine in the EU. Furthermore, in some commercial samples for human consumption, inadequate labelling was found because significant amounts of alkaloids were detected even though Papaver rhoeas L. seeds were declared on the product label.
    Keywords Papaver rhoeas ; Papaver somniferum ; adsorbents ; codeine ; humans ; liquid chromatography ; magnetism ; morphine ; narcotics ; papaverine ; silica ; solid phase extraction ; tandem mass spectrometry ; thebaine
    Language English
    Dates of publication 2021-0708
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods10071587
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: The hydrolysis of saponin-rich extracts from fenugreek and quinoa improves their pancreatic lipase inhibitory activity and hypocholesterolemic effect

    Navarro Del Hierro, Joaquín / Casado-Hidalgo, Gema / Reglero, Guillermo / Martin, Diana

    Food chemistry. 2021 Feb. 15, v. 338

    2021  

    Abstract: Saponins are promising compounds for ameliorating hyperlipidemia but scarce information exists about sapogenins, the hydrolyzed forms of saponins. Saponin-rich extracts and their hydrolysates from fenugreek (FE, HFE) and quinoa (QE, HQE), and saponin and ...

    Abstract Saponins are promising compounds for ameliorating hyperlipidemia but scarce information exists about sapogenins, the hydrolyzed forms of saponins. Saponin-rich extracts and their hydrolysates from fenugreek (FE, HFE) and quinoa (QE, HQE), and saponin and sapogenin standards, were assessed on the inhibition of pancreatic lipase and interference on the bioaccessibility of cholesterol by in vitro digestion models.All extracts inhibited pancreatic lipase (IC₅₀ between 1.15 and 0.59 mg/mL), although the hydrolysis enhanced the bioactivity of HQE (p = 0.014). The IC₅₀ value significantly correlated to the saponin content (r = −0.82; p = 0.001). Only the hydrolyzed extracts showed a reduction of bioaccessible cholesterol (p < 0.001) higher than that of phytosterols (35% reduction). Sapogenin standards exhibited no bioactivities, protodioscin and hederacoside C slightly inhibited the lipase (around 10%) and protodioscin reduced the bioaccessible cholesterol (23% reduction, p = 0.035).The hydrolysis process of saponin-rich extracts enhances the bioactivity and allows developing multibioactive products against pancreatic lipase and cholesterol absorption simultaneously.
    Keywords absorption ; bioavailability ; cholesteremic effect ; cholesterol ; digestion ; fenugreek ; food chemistry ; hydrolysis ; hyperlipidemia ; information ; phytosterols ; sapogenins ; saponins ; triacylglycerol lipase
    Language English
    Dates of publication 2021-0215
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-light
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2020.128113
    Database NAL-Catalogue (AGRICOLA)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: New Validated Method for the Determination of Six Opium Alkaloids in Poppy Seed-Containing Bakery Products by High-Performance Liquid Chromatography-Tandem Mass Spectrometry after Magnetic Solid-Phase Extraction

    Casado-Hidalgo, Gema / Martínez-García, Gonzalo / Morante-Zarcero, Sonia / Pérez-Quintanilla, Damián / Sierra, Isabel

    Journal of agricultural and food chemistry. 2022 June 08, v. 70, no. 24

    2022  

    Abstract: Bakery products containing poppy seeds are increasingly being commercialized. These seeds may be contaminated with latex from the Papaver somniferum L. plant rich in opium alkaloids (OAs). Therefore, health authorities demand the development of ... ...

    Abstract Bakery products containing poppy seeds are increasingly being commercialized. These seeds may be contaminated with latex from the Papaver somniferum L. plant rich in opium alkaloids (OAs). Therefore, health authorities demand the development of analytical methods to control them. In this study, an efficient and simple method was developed and validated for the first time to analyze six OAs in bakery products by high-performance liquid chromatography-tandem mass spectrometry. For this purpose, a solid–liquid extraction was optimized, and then a magnetic material [magnetite surface-modified with Fe(III) terephthalate, denoted as Fe₃O₄@TPA–Fe] was used for a fast magnetic solid-phase extraction. The method has been validated with adequate recoveries (70–110%) and relative standard deviations (<20%) and without matrix effects. Nine bakery samples (five breadsticks and four sliced bread) were analyzed; breadsticks showed low amounts of OAs, but two sliced bread showed higher amounts of OAs than the new amount (1.5 mg/kg) set by the Commission Regulation (EU) 2021/2142.
    Keywords Papaver somniferum ; breads ; food chemistry ; latex ; magnetic materials ; magnetism ; magnetite ; solid phase extraction ; tandem mass spectrometry
    Language English
    Dates of publication 2022-0608
    Size p. 7594-7606.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.2c01664
    Database NAL-Catalogue (AGRICOLA)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 1185: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Mesostructured Silica-Coated Magnetic Nanoparticles to Extract Six Opium Alkaloids in Poppy Seeds Prior to Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Analysis.

    Casado-Hidalgo, Gema / Pérez-Quintanilla, Damián / Morante-Zarcero, Sonia / Sierra, Isabel

    Foods (Basel, Switzerland)

    2021  Volume 10, Issue 7

    Abstract: In recent years, health authorities have become increasingly concerned about preventing consumer exposure to opium alkaloids present ... ...

    Abstract In recent years, health authorities have become increasingly concerned about preventing consumer exposure to opium alkaloids present in
    Language English
    Publishing date 2021-07-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods10071587
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: The hydrolysis of saponin-rich extracts from fenugreek and quinoa improves their pancreatic lipase inhibitory activity and hypocholesterolemic effect.

    Navarro Del Hierro, Joaquín / Casado-Hidalgo, Gema / Reglero, Guillermo / Martin, Diana

    Food chemistry

    2020  Volume 338, Page(s) 128113

    Abstract: Saponins are promising compounds for ameliorating hyperlipidemia but scarce information exists about sapogenins, the hydrolyzed forms of saponins. Saponin-rich extracts and their hydrolysates from fenugreek (FE, HFE) and quinoa (QE, HQE), and saponin and ...

    Abstract Saponins are promising compounds for ameliorating hyperlipidemia but scarce information exists about sapogenins, the hydrolyzed forms of saponins. Saponin-rich extracts and their hydrolysates from fenugreek (FE, HFE) and quinoa (QE, HQE), and saponin and sapogenin standards, were assessed on the inhibition of pancreatic lipase and interference on the bioaccessibility of cholesterol by in vitro digestion models. All extracts inhibited pancreatic lipase (IC
    MeSH term(s) Anticholesteremic Agents/chemistry ; Anticholesteremic Agents/pharmacology ; Chenopodium quinoa/chemistry ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Hydrolysis ; Lipase/antagonists & inhibitors ; Pancreas/enzymology ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Saponins/chemistry ; Trigonella/chemistry
    Chemical Substances Anticholesteremic Agents ; Enzyme Inhibitors ; Plant Extracts ; Saponins ; Lipase (EC 3.1.1.3)
    Language English
    Publishing date 2020-09-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2020.128113
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top