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  1. Article ; Online: Pyridoxine-Dependent Epilepsy as a Cause of Neonatal Seizures.

    Tsao, Hoi See / Case, Sarah D

    Rhode Island medical journal (2013)

    2022  Volume 105, Issue 2, Page(s) 17–21

    Abstract: Pediatric seizures are a common reason for emergency department visits. The highest risk of seizures in children is during the neonatal period. A low index of suspicion is important to facilitate the early assessment, workup, and treatment of inborn ... ...

    Abstract Pediatric seizures are a common reason for emergency department visits. The highest risk of seizures in children is during the neonatal period. A low index of suspicion is important to facilitate the early assessment, workup, and treatment of inborn errors of metabolism to optimize developmental outcomes. We present the rare case of a 9-day-old with seizures refractory to multiple anticonvulsant medications who was diagnosed with pyridoxine-dependent epilepsy. We review differences in the management of neonatal seizures from older patients, the utility of a trial of pyridoxine in refractory neonatal seizures, and the importance of preparing for emergent airway management given pyridoxine's ability to cause apnea and central nervous system depression.
    MeSH term(s) Epilepsy/complications ; Epilepsy/diagnosis ; Epilepsy/drug therapy ; Humans ; Infant, Newborn ; Pyridoxine/metabolism ; Pyridoxine/therapeutic use ; Seizures/etiology
    Chemical Substances Pyridoxine (KV2JZ1BI6Z)
    Language English
    Publishing date 2022-03-01
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 419430-5
    ISSN 2327-2228 ; 0363-7913
    ISSN (online) 2327-2228
    ISSN 0363-7913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 222: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Length of stay of pediatric mental health emergency department visits in the United States.

    Case, Sarah D / Case, Brady G / Olfson, Mark / Linakis, James G / Laska, Eugene M

    Journal of the American Academy of Child and Adolescent Psychiatry

    2011  Volume 50, Issue 11, Page(s) 1110–1119

    Abstract: Objective: To compare pediatric mental health emergency department visits to other pediatric emergency department visits, focusing on length of stay.: Method: We analyzed data from the National Hospital Ambulatory Medical Care Survey, a nationally ... ...

    Abstract Objective: To compare pediatric mental health emergency department visits to other pediatric emergency department visits, focusing on length of stay.
    Method: We analyzed data from the National Hospital Ambulatory Medical Care Survey, a nationally representative sample of US emergency department visits from 2001 to 2008, for patients aged ≤18 years (n = 73,015). Visits with a principal diagnosis of a mental disorder (n = 1,476) were compared to visits (n = 71,539) with regard to patient and hospital characteristics, treatment, and length of stay. Predictors of prolonged mental health visits were identified.
    Results: Mental health visits were more likely than other visits to arrive by ambulance (21.8% versus 6.3%, p < .001), to be triaged to rapid evaluation (27.9% versus 14.9%, p < .001), and to be admitted (16.4% versus 7.6%, p < .001) or transferred (15.7% versus 1.5%, p < .001). The median length of stay for mental health visits (169 minutes) significantly exceeded that of other visits (108 minutes). The odds of extended stay beyond 4 hours for mental health visits was almost twice that for other visits (adjusted odds ratio 1.9, 95% CI = 1.5-2.4) and was not explained by observed differences in evaluation, treatment, or disposition. Among mental health visits, advancing calendar year of study, intentional self-injury, age 6-13 years, Northeastern, Southern, and metropolitan hospital location, use of laboratory studies, and patient transfer all predicted extended stays.
    Conclusions: Compared with other pediatric emergency visits, mental health visits are longer, are more frequently triaged to urgent evaluation, and more likely to result in patient admission or transfer, thereby placing distinctive burdens on US emergency departments.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Emergency Services, Psychiatric/statistics & numerical data ; Female ; Health Surveys ; Humans ; Infant ; Length of Stay/statistics & numerical data ; Male ; Mental Disorders/diagnosis ; Mental Disorders/epidemiology ; Mental Disorders/therapy ; United States/epidemiology
    Language English
    Publishing date 2011-10-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 392535-3
    ISSN 1527-5418 ; 0890-8567
    ISSN (online) 1527-5418
    ISSN 0890-8567
    DOI 10.1016/j.jaac.2011.08.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Um IV Zs.163: Show issues Location:
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