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  1. Book ; Online: Chapter Traveling towards fame: Albert Einstein and the Eddington eclipse expedition to Príncipe and Sobral in 1919

    Casetti, Lapo

    (Studi e saggi)

    2021  

    Series title Studi e saggi
    Keywords Einstein ; Eddington ; general relativity ; solar eclipse ; São Tomé and Príncipe
    Language 0|e
    Size 1 electronic resource (20 pages)
    Publisher Firenze University Press
    Publishing place Florence
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021614200
    ISBN 9788855184670 ; 8855184679
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Temperature inversion in a gravitationally bound plasma

    Barbieri, Luca / Casetti, Lapo / Verdini, Andrea / Landi, Simone

    the case of the solar corona

    2023  

    Abstract: The temperature of the solar atmosphere increases from thousands to millions of degrees moving from the lower layer, the chromosphere, to the outermost one, the corona, while density drops by several orders of magnitude. Such a phenomenon is called ... ...

    Abstract The temperature of the solar atmosphere increases from thousands to millions of degrees moving from the lower layer, the chromosphere, to the outermost one, the corona, while density drops by several orders of magnitude. Such a phenomenon is called temperature inversion and how it happens is still largely unknown. We argue that temperature fluctuations in the chromosphere play a key role, as suggested by the study of a kinetic model of a plasma confined in a semicircular tube subjected to the gravity of the Sun and in contact with a thermostat at its feet, mimicking a coronal loop anchored in the chromosphere. Collisions are neglected in the corona, with a sharp transition to a fully collisional chromosphere. Numerical simulations and analytical calculations show that suitable fluctuations of the thermostat temperature drive the plasma towards a non-thermal stationary state with temperature and density profiles strikingly similar to those observed in the atmosphere of the Sun, suggesting this mechanism may significantly contribute to coronal heating.

    Comment: 7 pages, 3 figures, REVTeX 4.1. Submitted to Physical Review Letters on March 21, 2023, revised August 10, 2023
    Keywords Astrophysics - Solar and Stellar Astrophysics ; Condensed Matter - Statistical Mechanics
    Subject code 612
    Publishing date 2023-09-27
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Modeling hydration water and its role in polymer folding.

    Bruscolini, P / Casetti, L

    Journal of biological physics

    2013  Volume 27, Issue 2-3, Page(s) 243–256

    Abstract: The hydrophobic effect is the dominant force which drives a proteintowards its native state, but its physics has not been thoroughlyunderstood yet. We introduce an exactly solvable model of the solvation ofnon-polar molecules in water, which shows that ... ...

    Abstract The hydrophobic effect is the dominant force which drives a proteintowards its native state, but its physics has not been thoroughlyunderstood yet. We introduce an exactly solvable model of the solvation ofnon-polar molecules in water, which shows that the reduced number ofallowed configurations of water molecules when the solute is present isenough to give rise to hydrophobic behaviour. We apply our model to anon-polar homopolymer in aqueous solution, obtaining a clear evidence ofboth `cold' and `warm' collapse transitions that recall those of proteins.Finally we show how the model can be adapted to describe the solvation ofaromatic and polar molecules.
    Language English
    Publishing date 2013-01-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2016734-9
    ISSN 1573-0689 ; 0092-0606
    ISSN (online) 1573-0689
    ISSN 0092-0606
    DOI 10.1023/A:1013194012354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Violent relaxation in the Hamiltonian Mean Field model

    Giachetti, Guido / Casetti, Lapo

    I. Cold collapse and effective dissipation

    2019  

    Abstract: In $N$-body systems with long-range interactions mean-field effects dominate over binary interactions (collisions), so that relaxation to thermal equilibrium occurs on time scales that grow with $N$, diverging in the $N\to\infty$ limit. However, a faster ...

    Abstract In $N$-body systems with long-range interactions mean-field effects dominate over binary interactions (collisions), so that relaxation to thermal equilibrium occurs on time scales that grow with $N$, diverging in the $N\to\infty$ limit. However, a faster and non-collisional relaxation process, referred to as violent relaxation, sets in when starting from generic initial conditions: collective oscillations (referred to as virial oscillations) develop and damp out on timescales not depending on the system's size. After the damping of such oscillations the system is found in a quasi-stationary state that survives virtually forever when the system is very large. During violent relaxation the distribution function obeys the collisionless Boltzmann (or Vlasov) equation, that, being invariant under time reversal, does not "naturally" describe a relaxation process. Indeed, the dynamics is moved to smaller and smaller scales in phase space as time goes on, so that observables that do not depend on small-scale details appear as relaxed after a short time. We propose an approximation scheme to describe collisionless relaxation, based on the introduction of moments of the distribution function, and apply it to the Hamiltonian Mean Field (HMF) model. To the leading order, virial oscillations are equivalent to the motion of a particle in a one-dimensional potential. Inserting higher-order contributions in an effective way, inspired by the Caldeira-Leggett model of quantum dissipation, we derive a dissipative equation describing the damping of the oscillations, including a renormalization of the effective potential and yielding predictions for collective properties of the system after the damping in very good agreement with numerical simulations. Here we restrict ourselves to "cold" initial conditions; generic initial conditions will be considered in a forthcoming paper.

    Comment: 22 pages, 10 figures
    Keywords Condensed Matter - Statistical Mechanics ; Astrophysics - Astrophysics of Galaxies
    Subject code 612
    Publishing date 2019-02-06
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Robotic spleen-preserving distal pancreatectomy: the Verona experience.

    Esposito, A / Casetti, L / De Pastena, M / Ramera, M / Montagnini, G / Landoni, L / Bassi, C / Salvia, R

    Updates in surgery

    2020  Volume 73, Issue 3, Page(s) 923–928

    Abstract: Background: The minimally invasive approach in spleen-preserving distal pancreatectomy has currently been emphasized in benign and pre-malignant pancreatic diseases. The study aims to demonstrate the safety and feasibility of our technique of robotic ... ...

    Abstract Background: The minimally invasive approach in spleen-preserving distal pancreatectomy has currently been emphasized in benign and pre-malignant pancreatic diseases. The study aims to demonstrate the safety and feasibility of our technique of robotic spleen-preserving distal pancreatectomy (RSPDP) by a stepwise approach.
    Methods: The data of consecutive patients presented for RSPDP from 2014 to 2019 at Verona University were retrieved from a prospectively maintained database. The patients were divided into two groups based on the surgical procedure performed, such as Kimura's (KG) or Warshaw's (WG) technique, and then compared.
    Results: In the study period, 32 patients underwent RSPDP. Twenty-three patients presented for the Kimura procedure (72%), while nine patients underwent the Warshaw procedure (28%). A higher body mass index was found in the KG (26 ± 4 vs. 22 ± 3, p = 0.037). Regarding the pathological data, the WG group differed in the tumor dimension, and the lymph nodes harvested (30 ± 2 vs. 17 ± 10, 9 ± 5 vs. 3 ± 4, p = 0.0028, and p = 0.005, respectively). Notably, no conversions and mortality were recorded. The overall morbidity was 25% ( eight patients) with no difference between the groups (p = 0.820). The mean length of stay was 8 days, and was similar between the groups (p = 0.350).
    Conclusions: The present study suggests that RSPDP is a valid option for the treatment of benign or pre-malignant pancreatic diseases of the distal pancreas, with comparable morbidity with the standard treatment and no mortality. Further research is needed to standardize the technique and to assess the immunological, surgical, and financial benefits of the procedure.
    MeSH term(s) Humans ; Laparoscopy ; Pancreatectomy ; Pancreatic Neoplasms/surgery ; Robotic Surgical Procedures ; Spleen/surgery
    Keywords covid19
    Language English
    Publishing date 2020-03-11
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-020-00731-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Monte Carlo simulations in the unconstrained ensemble.

    Latella, Ivan / Campa, Alessandro / Casetti, Lapo / Di Cintio, Pierfrancesco / Rubi, J Miguel / Ruffo, Stefano

    Physical review. E

    2021  Volume 103, Issue 6, Page(s) L061303

    Abstract: The unconstrained ensemble describes completely open systems whose control parameters are the chemical potential, pressure, and temperature. For macroscopic systems with short-range interactions, thermodynamics prevents the simultaneous use of these ... ...

    Abstract The unconstrained ensemble describes completely open systems whose control parameters are the chemical potential, pressure, and temperature. For macroscopic systems with short-range interactions, thermodynamics prevents the simultaneous use of these intensive variables as control parameters, because they are not independent and cannot account for the system size. When the range of the interactions is comparable with the size of the system, however, these variables are not truly intensive and may become independent, so equilibrium states defined by the values of these parameters may exist. Here, we derive a Monte Carlo algorithm for the unconstrained ensemble and show that simulations can be performed using the chemical potential, pressure, and temperature as control parameters. We illustrate the algorithm by applying it to physical systems where either the system has long-range interactions or is confined by external conditions. The method opens up an avenue for the simulation of completely open systems exchanging heat, work, and matter with the environment.
    Language English
    Publishing date 2021-07-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.103.L061303
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intraoperative Blood Loss Estimation in Hepato-pancreato-biliary Surgery- Relevant, Not Reported, Not Standardized: Results From a Systematic Review and a Worldwide Snapshot Survey.

    Perri, Giampaolo / Marchegiani, Giovanni / Reich, Federico / Casetti, Luca / Fontana, Martina / Esposito, Alessandro / Ruzzenente, Andrea / Salvia, Roberto / Bassi, Claudio

    Annals of surgery

    2022  Volume 277, Issue 4, Page(s) e849–e855

    Abstract: Objective: To provide an overview of the current practice of intraoperative blood loss (BL) estimation in hepato-pancreato-biliary (HPB) surgery.: Background: Intraoperative BL is a major quality marker in HPB surgery and a predictor of perioperative ...

    Abstract Objective: To provide an overview of the current practice of intraoperative blood loss (BL) estimation in hepato-pancreato-biliary (HPB) surgery.
    Background: Intraoperative BL is a major quality marker in HPB surgery and a predictor of perioperative outcomes. However, the method for BL estimation is not standardized.
    Methods: A systematic review was performed of original studies published between 2006 and 2021 reporting the intraoperative BL of patients undergoing pancreatic or hepatic resections. A web-based snapshot survey was distributed globally to all members of the International Hepato-Pancreato-Biliary Association (IHPBA).
    Results: A total of 806 studies were included; 480 (60%) had BL as their primary outcome, and 105 (13%) had BL as their secondary outcome. However, 669 (83%) did not specify how BL estimation was performed, and 9 different methods were found among the remaining 136 (17%) studies.The survey was completed by 252 surgeons. Most of the responders (94%) declared that they systematically performed BL estimation and considered BL predictive of postoperative complications after pancreatic (73%) and liver (74%) resection. All methods previously identified in the literature were used by responders with different frequencies. A calculation based on suction fluid amounts, operative gauze weight, and irrigation was the most used method in the literature (7%) and among responders (51%). Most responders (83%) felt that BL estimation in HPB surgery needs improved standardization.
    Conclusions: Standardization of intraoperative BL estimation is urgently needed in HPB surgery to ensure the consistency of reporting and reproducibility.
    MeSH term(s) Humans ; Blood Loss, Surgical ; Reproducibility of Results ; Biliary Tract Surgical Procedures ; Liver/surgery ; Pancreas/surgery
    Language English
    Publishing date 2022-07-15
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000005536
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Robotic Dual-Console Distal Pancreatectomy: Could it be Considered a Safe Approach and Surgical Teaching even in Pancreatic Surgery? A Retrospective Observational Study Cohort.

    De Pastena, M / Salvia, R / Paiella, S / Deiro, G / Bannone, E / Balduzzi, A / Giuliani, T / Casetti, L / Ramera, M / Filippini, C / Montagnini, G / Landoni, L / Esposito, A

    World journal of surgery

    2021  Volume 45, Issue 10, Page(s) 3191–3197

    Abstract: Background: The study aims to assess the safety and feasibility of the robotic dual-console during a robotic distal pancreatectomy METHODS: The data of the consecutive patients submitted to RDP from 2012 to 2019 at the Verona University were retrieved ... ...

    Abstract Background: The study aims to assess the safety and feasibility of the robotic dual-console during a robotic distal pancreatectomy METHODS: The data of the consecutive patients submitted to RDP from 2012 to 2019 at the Verona University were retrieved from a prospectively maintained database. The patients submitted to RDP were divided into the dual-console platform group (DG) and compared to the standard robotic procedure group (SG).
    Results: In the study period, 102 robotic distal pancreatectomies were performed, of whom 42 patients (41%) belonged to the DG and 60 patients (59%) to the SG. Higher operation time was recorded in the DG compared to the SG (410 vs. 265 min, p < 0.001). The overall conversion rate of the series was 7% (n 7 patients). All the conversions were observed in the SG (p = 0.021). No differences in morbidity or pancreatic fistula rate were recorded (p > 0.05). No mortality events in the 90th postoperative days were reported in this series.
    Conclusions: The robotic dual-console approach for distal pancreatectomy is safe, feasible, and reproducible. The postoperative surgical outcomes are comparable to the standard RDP with the single-console da Vinci Surgical System®. This surgical technique can widely and safely improve the robotic surgical training program.
    MeSH term(s) Humans ; Laparoscopy ; Operative Time ; Pancreatectomy ; Pancreatic Fistula/epidemiology ; Pancreatic Fistula/etiology ; Pancreatic Neoplasms/surgery ; Retrospective Studies ; Robotic Surgical Procedures/adverse effects ; Robotics
    Language English
    Publishing date 2021-07-24
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-021-06216-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Modified Thirring model beyond the excluded-volume approximation

    Campa, Alessandro / Casetti, Lapo / Di Cintio, Pierfrancesco / Latella, Ivan / Rubi, J. Miguel / Ruffo, Stefano

    2022  

    Abstract: Long-range interacting systems may exhibit ensemble inequivalence and can possibly attain equilibrium states under completely open conditions, for which energy, volume and number of particles simultaneously fluctuate. Here we consider a modified version ... ...

    Abstract Long-range interacting systems may exhibit ensemble inequivalence and can possibly attain equilibrium states under completely open conditions, for which energy, volume and number of particles simultaneously fluctuate. Here we consider a modified version of the Thirring model for self-gravitating systems with attractive and repulsive long-range interactions in which particles are treated as hard spheres in dimension d=1,2,3. Equilibrium states of the model are studied under completely open conditions, in the unconstrained ensemble, by means of both Monte Carlo simulations and analytical methods and are compared with the corresponding states at fixed number of particles, in the isothermal-isobaric ensemble. Our theoretical description is performed for an arbitrary local equation of state, which allows us to examine the system beyond the excluded-volume approximation. The simulations confirm the theoretical prediction of the possible occurrence of first-order phase transitions in the unconstrained ensemble. This work contributes to the understanding of long-range interacting systems exchanging heat, work and matter with the environment.

    Comment: 26 pages, 8 figures
    Keywords Condensed Matter - Statistical Mechanics
    Subject code 612
    Publishing date 2022-06-09
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Thirty-day prevalence and clinical impact of fluid collections at the resection margin after distal pancreatectomy: Follow-up of a multicentric randomized controlled trial.

    De Pastena, Matteo / Bannone, Elisa / Fontana, Martina / Paiella, Salvatore / Esposito, Alessandro / Casetti, Luca / Landoni, Luca / Tuveri, Massimiliano / Pea, Antonio / Casciani, Fabio / Zamboni, Giulia / Frigerio, Isabella / Marchegiani, Giovanni / Butturini, Giovanni / Malleo, Giuseppe / Salvia, Roberto

    Surgery

    2024  

    Abstract: Background: Postoperative fluid collections at the resection margin of the pancreatic stump are frequent after distal pancreatectomy, yet their clinical impact is unclear. The aim of this study was to assess the 30-day prevalence of postoperative fluid ... ...

    Abstract Background: Postoperative fluid collections at the resection margin of the pancreatic stump are frequent after distal pancreatectomy, yet their clinical impact is unclear. The aim of this study was to assess the 30-day prevalence of postoperative fluid collections after distal pancreatectomy and the factors associated with a clinically relevant condition.
    Methods: Patients enrolled in a randomized controlled trial of parenchymal transection with either reinforced, triple-row staple, or ultrasonic dissector underwent routine magnetic resonance 30 days postoperatively. Postoperative fluid collection was defined as a cyst-like lesion of at least 1 cm at the pancreatic resection margin. Postoperative fluid collections requiring any therapy were defined as clinically relevant.
    Results: A total of 133 patients were analyzed; 69 were in the triple-row staple transection arm, and 64 were in the ultrasonic dissector transection arm. The overall 30-day prevalence of postoperative fluid collections was 68% (n = 90), without any significant difference between the two trial arms. Postoperative serum hyperamylasemia was more frequent in patients with postoperative fluid collections than those without (31% vs 7%, P = .001). Among the postoperative fluid collection population, an early postoperative pancreatic fistula (odds ratio 14.9, P = .002), post pancreatectomy acute pancreatitis (odds ratio 12.7, P = .036), and postoperative fluid collection size larger than 50 mm (odds ratio 6.6, P = .046) were independently associated with a clinically relevant postoperative fluid collection.
    Conclusion: Postoperative fluid collections at the resection margin are common after distal pancreatectomy and can be predicted by early assessment of postoperative serum hyperamylasemia. A preceding pancreatectomy acute pancreatitis and/or postoperative pancreatic fistula and large collections (>50 mm) were associated with a clinically relevant postoperative fluid collection, representing targets for closer follow-up or earlier therapeutic interventions.
    Language English
    Publishing date 2024-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202467-6
    ISSN 1532-7361 ; 0039-6060
    ISSN (online) 1532-7361
    ISSN 0039-6060
    DOI 10.1016/j.surg.2024.03.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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