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  1. Article ; Online: Subchronic inhalation exposure to ultrafine particulate matter alters the intestinal microbiome in various mouse models.

    Chang, Candace / Gupta, Rajat / Sedighian, Farzaneh / Louie, Allen / Gonzalez, David M / Le, Collin / Cho, Jae Min / Park, Seul-Ki / Castellanos, Jocelyn / Ting, To-Wei / Dong, Tien S / Arias-Jayo, Nerea / Lagishetty, Venu / Navab, Mohamad / Reddy, Srinivasa / Sioutas, Constantinos / Hsiai, Tzung / Jacobs, Jonathan P / Araujo, Jesus A

    Environmental research

    2024  Volume 248, Page(s) 118242

    Abstract: Exposure to ultrafine particles (UFPs) has been associated with multiple adverse health effects. Inhaled UFPs could reach the gastrointestinal tract and influence the composition of the gut microbiome. We have previously shown that oral ingestion of UFPs ...

    Abstract Exposure to ultrafine particles (UFPs) has been associated with multiple adverse health effects. Inhaled UFPs could reach the gastrointestinal tract and influence the composition of the gut microbiome. We have previously shown that oral ingestion of UFPs alters the gut microbiome and promotes intestinal inflammation in hyperlipidemic Ldlr
    MeSH term(s) Mice ; Animals ; Particulate Matter/analysis ; Gastrointestinal Microbiome ; Air Pollutants/toxicity ; Inhalation Exposure/analysis ; RNA, Ribosomal, 16S ; Cross-Sectional Studies ; Mice, Inbred C57BL ; Disease Models, Animal ; Inflammation/chemically induced
    Chemical Substances Particulate Matter ; Air Pollutants ; RNA, Ribosomal, 16S
    Language English
    Publishing date 2024-01-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2024.118242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A novel probiotic, Lactobacillus johnsonii 456, resists acid and can persist in the human gut beyond the initial ingestion period.

    Davoren, Michael J / Liu, Jared / Castellanos, Jocelyn / Rodríguez-Malavé, Norma I / Schiestl, Robert H

    Gut microbes

    2018  Volume 10, Issue 4, Page(s) 458–480

    Abstract: Probiotics are considered to have multiple beneficial effects on the human gastrointestinal tract, including immunomodulation, pathogen inhibition, and improved host nutrient metabolism. However, extensive characterization of these properties is needed ... ...

    Abstract Probiotics are considered to have multiple beneficial effects on the human gastrointestinal tract, including immunomodulation, pathogen inhibition, and improved host nutrient metabolism. However, extensive characterization of these properties is needed to define suitable clinical applications for probiotic candidates.
    MeSH term(s) Antibiosis ; Bacterial Adhesion ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Bile Acids and Salts/metabolism ; Caco-2 Cells ; Cell Line, Tumor ; Gastric Acid/metabolism ; Gastrointestinal Tract/microbiology ; Genetic Variation ; Genome, Bacterial/genetics ; Humans ; Lactobacillus johnsonii/physiology ; Phylogeny ; Probiotics ; Yogurt/microbiology
    Chemical Substances Bacterial Proteins ; Bile Acids and Salts
    Language English
    Publishing date 2018-12-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2575755-6
    ISSN 1949-0984 ; 1949-0984
    ISSN (online) 1949-0984
    ISSN 1949-0984
    DOI 10.1080/19490976.2018.1547612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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