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Article ; Online: Family Structure is Associated with Mental Health and Attention Deficit (Hyperactivity) Disorders in Adolescents with Type 1 Diabetes.

Baechle, Christina / Stahl-Pehe, Anna / Castillo, Katty / Holl, Reinhard W / Rosenbauer, Joachim

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association

2022 Volume 130, Issue 9, Page(s) 604–613

Abstract: Objective: To analyze the cross-sectional associations of family structure with mental health and attention deficit (hyperactivity) disorders (AD(H)D) in 11- to 17-year-old adolescents with early-onset type 1 diabetes participating in one of three ... ...

Abstract	Objective: To analyze the cross-sectional associations of family structure with mental health and attention deficit (hyperactivity) disorders (AD(H)D) in 11- to 17-year-old adolescents with early-onset type 1 diabetes participating in one of three baseline surveys as part of an ongoing cohort study. Methods: Parents (n=1,631) completed the Strengths and Difficulties Questionnaire to screen for their child's mental health and answered questions about their child's diagnosis of AD(H)D. Associations between mental health or AD(H)D and family structure were analyzed using multivariable logistic regression analyses adjusted for various personal and diabetes-related variables. Results: Compared to adolescents living with both parents, adolescents living with one parent and his/her partner had 2.35 (95% confidence interval 1.32; 4.21) higher odds of abnormal screening result and 2.08 (1.09; 3.95) higher odds of a borderline screening result while adolescents living with a single parent had 1.84 (1.07; 3.17)/1.08 (0.53; 2.21) higher odds of abnormal/borderline screening results. The odds ratios for diagnosed attention deficit (hyperactivity) disorder were 2.17 (0.98; 4.84) for adolescents living with one parent and his/her partner and 1.27 (0.54; 3.01) for those living with a single parent vs. both parents. Conclusions: Our results indicate higher odds of mental health problems and AD(H)D in adolescents with type 1 diabetes who do not live with both parents; this finding was most pronounced in individuals living with one parent and his/her partner vs. both parents. Longitudinal studies are needed to verify our results and elucidate the underlying mechanisms.
MeSH term(s)	Adolescent ; Attention Deficit Disorder with Hyperactivity/complications ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Attention Deficit Disorder with Hyperactivity/psychology ; Child ; Cohort Studies ; Cross-Sectional Studies ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/epidemiology ; Female ; Humans ; Male ; Mental Disorders/complications ; Mental Disorders/epidemiology ; Mental Health ; Odds Ratio ; Surveys and Questionnaires
Language	English
Publishing date	2022-03-31
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1225416-2
ISSN	1439-3646 ; 0947-7349
ISSN (online)	1439-3646
ISSN	0947-7349
DOI	10.1055/a-1729-7972
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Article ; Online: Course of screening-based depression in young adults with a long type 1 diabetes duration: Prevalence and transition probabilities - A cohort study.

Baechle, Christina / Stahl-Pehe, Anna / Castillo, Katty / Lange, Karin / Holl, Reinhard W / Rosenbauer, Joachim

Diabetes research and clinical practice

2022 Volume 185, Page(s) 109220

Abstract: Aims: To extend the current knowledge of the prevalence and course of screening-based depression (SBD) and its predictors in emerging adults with a long type 1 diabetes duration.: Methods: A total of 487 young adults (64.7% women, mean age 24.0 years) ...

Abstract	Aims: To extend the current knowledge of the prevalence and course of screening-based depression (SBD) and its predictors in emerging adults with a long type 1 diabetes duration. Methods: A total of 487 young adults (64.7% women, mean age 24.0 years) who participated in a nationwide cohort study provided data on SBD (Patient Health Questionnaire (PHQ-9) score ≥ 10). We estimated the overall and age- and sex-specific prevalence of SBD, identified the associated covariates, and determined the transition probabilities between SBD states using adjusted first-order Markov transition models. Results: The prevalence of SBD was 17.7% in women and 7.0% in men. A total of 70.4% (95%-CI 57.4%; 80.8%) of the participants with SBD at the first screening still had SBD at the three-year follow-up. Of the subjects without SBD at baseline, 6.9% (4.9%; 9.8%) had SBD at follow-up. The main predictor of current SBD was previous SBD (OR 39.0 (15.4; 98.6)), followed by living in one's own or in a shared apartment vs. living with both parents (OR: 2.75 (1.03; 7.36)). Conclusions: Using an innovative analytical approach, emerging adults with a long diabetes duration demonstrated a moderate rate of incident SBD but a high rate of persistent SBD.
MeSH term(s)	Adult ; Cohort Studies ; Depression/diagnosis ; Depression/epidemiology ; Diabetes Mellitus, Type 1/diagnosis ; Diabetes Mellitus, Type 1/epidemiology ; Female ; Humans ; Male ; Prevalence ; Probability ; Young Adult
Language	English
Publishing date	2022-01-31
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	632523-3
ISSN	1872-8227 ; 0168-8227
ISSN (online)	1872-8227
ISSN	0168-8227
DOI	10.1016/j.diabres.2022.109220
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Article ; Online: Role of Rotavirus Vaccination in Decline in Incidence of Type 1 Diabetes.

Rosenbauer, Joachim / Castillo, Katty / Bächle, Christina

JAMA pediatrics

2019 Volume 173, Issue 9, Page(s) 893–894

Language	English
Publishing date	2019-07-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2701223-2
ISSN	2168-6211 ; 2168-6203
ISSN (online)	2168-6211
ISSN	2168-6203
DOI	10.1001/jamapediatrics.2019.2466
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Article: Overestimation and underestimation of youths' health-related quality of life are associated with youth and caregiver positive screens for depression: results of a population-based study among youths with longstanding type 1 diabetes.

Stahl-Pehe, Anna / Selinski, Silvia / Bächle, Christina / Castillo, Katty / Lange, Karin / Holl, Reinhard W / Rosenbauer, Joachim

Diabetology & metabolic syndrome

2022 Volume 14, Issue 1, Page(s) 40

Abstract: Background: This study aimed to analyze the extent and direction of disagreement between self- and proxy-reported quality of life (QoL) and the factors associated with QoL overestimation and underestimation by caregivers compared with self-reports.: ... ...

Abstract	Background: This study aimed to analyze the extent and direction of disagreement between self- and proxy-reported quality of life (QoL) and the factors associated with QoL overestimation and underestimation by caregivers compared with self-reports. Methods: This study used data from population-based questionnaire surveys conducted in 2012-2013 and 2015-2016 with 11- to 17-year-olds with a duration of type 1 diabetes of 10 years or longer and their caregivers (n = 1058). QoL in youth was assessed via 10-item KIDSCREEN (KIDSCREEN-10) self- and proxy-reported questionnaires. The scores ranged from 0 to 100, with higher scores indicating better QoL. Depression screening was performed via the Center for Epidemiological Studies Depression Scale for Children for youths (CES-DC screen positive: score > 15) and WHO-5 Well-being Index for parents/caregivers (WHO-5 screen positive: score ≤ 50). Results: The mean self- and proxy-reported normalized KIDSCREEN-10 scores were 64.2 (standard deviation [SD] 11.4) and 66.1 (11.5), respectively. More caregivers overestimated (self-reported minus proxy-reported score < - 0.5SD self-reported score) than underestimated (self-reported minus proxy-reported score > 0.5SD self-reported score) youths' QoL (37% versus 23%, p < 0.001). Youths who screened positive for depression (18%) were at higher risk of their QoL being overestimated and lower risk of their QoL being underestimated by caregivers than youths who screened negative for depression (RR Conclusions: Caregivers often over- or underestimated their children's QoL. Positive screens for depression among both youths and caregivers contributed to the observed differences between self- and caregiver-reported QoL.
Language	English
Publishing date	2022-03-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2518786-7
ISSN	1758-5996
ISSN	1758-5996
DOI	10.1186/s13098-022-00809-w
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Article ; Online: Screening for generalized anxiety disorder (GAD) and associated factors in adolescents and young adults with type 1 diabetes: Cross-sectional results of a Germany-wide population-based study.

Stahl-Pehe, Anna / Selinski, Silvia / Bächle, Christina / Castillo, Katty / Lange, Karin / Holl, Reinhard W / Rosenbauer, Joachim

Diabetes research and clinical practice

2022 Volume 184, Page(s) 109197

Abstract: Aims: The aims of this study were to screen 14- to 30-year-olds with early-onset type 1 diabetes for generalized anxiety disorder (GAD) and to compare the characteristics of the study participants who had a positive result for GAD with those who had a ... ...

Abstract	Aims: The aims of this study were to screen 14- to 30-year-olds with early-onset type 1 diabetes for generalized anxiety disorder (GAD) and to compare the characteristics of the study participants who had a positive result for GAD with those who had a negative result. Methods: This study used data from a questionnaire survey conducted from 2018 to 2019. The GAD-7 questionnaire was used to screen for GAD (positive: GAD-7 score ≥ 10). All regression analyses were adjusted for age, sex, depression diagnosis and considered multiple testing. Results: The 713 participants had a mean GAD-7 score of 4.32 (SD 4.18). A total of 12% of the study population (10% of adolescents, 13% of adults) was screened positive for GAD. Positive screening results were associated with impairments in various domains, such as self-assessed physical performance (RR Conclusions: Diabetologists should be aware that adolescents and young adults with GAD symptoms might experience extensive impairments in their daily lives.
MeSH term(s)	Adolescent ; Anxiety/epidemiology ; Anxiety Disorders/diagnosis ; Anxiety Disorders/epidemiology ; Cross-Sectional Studies ; Diabetes Mellitus, Type 1/diagnosis ; Diabetes Mellitus, Type 1/epidemiology ; Germany/epidemiology ; Humans ; Young Adult
Language	English
Publishing date	2022-01-19
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	632523-3
ISSN	1872-8227 ; 0168-8227
ISSN (online)	1872-8227
ISSN	0168-8227
DOI	10.1016/j.diabres.2022.109197
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Article: [No title information]

Baechle, Christina / Stahl-Pehe, Anna / Castillo, Katty / Holl, Reinhard W. / Rosenbauer, Joachim

Experimental and Clinical Endocrinology & Diabetes

2022 Volume 130, Issue 09, Page(s) 604–613

Abstract	Objective: To analyze the cross-sectional associations of family structure with mental health and attention deficit (hyperactivity) disorders (AD(H)D) in 11- to 17-year-old adolescents with early-onset type 1 diabetes participating in one of three baseline surveys as part of an ongoing cohort study. Methods: Parents (n=1,631) completed the Strengths and Difficulties Questionnaire to screen for their child’s mental health and answered questions about their child’s diagnosis of AD(H)D. Associations between mental health or AD(H)D and family structure were analyzed using multivariable logistic regression analyses adjusted for various personal and diabetes-related variables. Results: Compared to adolescents living with both parents, adolescents living with one parent and his/her partner had 2.35 (95% confidence interval 1.32; 4.21) higher odds of abnormal screening result and 2.08 (1.09; 3.95) higher odds of a borderline screening result while adolescents living with a single parent had 1.84 (1.07; 3.17)/1.08 (0.53; 2.21) higher odds of abnormal/borderline screening results. The odds ratios for diagnosed attention deficit (hyperactivity) disorder were 2.17 (0.98; 4.84) for adolescents living with one parent and his/her partner and 1.27 (0.54; 3.01) for those living with a single parent vs. both parents. Conclusions: Our results indicate higher odds of mental health problems and AD(H)D in adolescents with type 1 diabetes who do not live with both parents; this finding was most pronounced in individuals living with one parent and his/her partner vs. both parents. Longitudinal studies are needed to verify our results and elucidate the underlying mechanisms.
Keywords	attention deficit hyperactivity disorder ; ADHD ; adolescence ; psychology ; T1D ; childhood diabetes
Language	English
Publishing date	2022-03-31
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	1225416-2
ISSN	1439-3646 ; 0947-7349
ISSN (online)	1439-3646
ISSN	0947-7349
DOI	10.1055/a-1729-7972
Database	Thieme publisher's database

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Article ; Online: Association of family structure with type 1 diabetes management and outcomes in adolescents: A population-based cross-sectional survey.

Baechle, Christina / Stahl-Pehe, Anna / Castillo, Katty / Selinski, Silvia / Holl, Reinhard W / Rosenbauer, Joachim

Pediatric diabetes

2020 Volume 22, Issue 3, Page(s) 482–494

Abstract: Background: Diabetes therapies have enormously changed during past decades, but only few studies have analyzed the association between family structure and diabetes management and outcomes.: Objective: To analyze cross-sectionally the associations of ...

Abstract	Background: Diabetes therapies have enormously changed during past decades, but only few studies have analyzed the association between family structure and diabetes management and outcomes. Objective: To analyze cross-sectionally the associations of family structure with type 1 diabetes (T1D) management and various diabetes outcomes. Methods: A total of 1635 11- to 17-year-old participants and their parents completed one of three baseline surveys as part of a nationwide, population-based cohort study on early-onset, long-standing T1D. Associations between family structure and outcome variables were analyzed by multivariable linear/logistic regression. Results: Compared to adolescents living with both parents (reference), HbA Conclusions: Living with only one parent with or without a new partner was associated with less SMBG and pump use and poor diabetes outcomes. Future studies to explore the underlying mechanisms are required.
MeSH term(s)	Adolescent ; Blood Glucose Self-Monitoring ; Child ; Cohort Studies ; Cross-Sectional Studies ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/drug therapy ; Family Characteristics ; Female ; Glycated Hemoglobin A/metabolism ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Insulin Infusion Systems ; Male
Chemical Substances	Glycated Hemoglobin A ; Hypoglycemic Agents ; Insulin
Language	English
Publishing date	2020-12-29
Publishing country	Denmark
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1502504-4
ISSN	1399-5448 ; 1745-1426 ; 1399-543X
ISSN (online)	1399-5448
ISSN	1745-1426 ; 1399-543X
DOI	10.1111/pedi.13166
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Article ; Online: Pulmonary Findings in Hospitalized COVID-19 Patients Assessed by Lung Ultrasonography (LUS) - A Prospective Registry Study.

Barner, Anna / Burian, Egon / Simon, Alexander / Castillo, Katty / Waschulzik, Birgit / Braren, Rickmer / Heemann, Uwe / Osterwalder, Joseph / Spiel, Alexander / Heim, Markus / Stock, Konrad Friedrich

Ultraschall in der Medizin (Stuttgart, Germany : 1980)

2023 Volume 44, Issue 5, Page(s) e248–e256

Abstract: Purpose: This prospective two-centre study investigated localisation-dependent lesion patterns in COVID-19 with standard lung ultrasonography (LUS) and their relationship with thoracic computed tomography (CT) and clinical parameters.: Materials and ... ...

Title translation	Lungenbefunde bei hospitalisierten COVID-19-Patienten erfasst mittels Lungensonografie (LUS) – Eine prospektive Registerstudie.
Abstract	Purpose: This prospective two-centre study investigated localisation-dependent lesion patterns in COVID-19 with standard lung ultrasonography (LUS) and their relationship with thoracic computed tomography (CT) and clinical parameters. Materials and methods: Between April 2020 and April 2021, 52 SARS-CoV-2-positive patients in two hospitals were examined by means of LUS for "B-lines", fragmented pleura, consolidation and air bronchogram in 12 lung regions and for pleural effusions. A newly developed LUS score based on the number of features present was correlated with clinical parameters (respiration, laboratory parameters) and the CT and analysed with respect to the 30- and 60-day outcome. All patients were offered an outpatient LUS follow-up. Results: The LUS and CT showed a bilateral, partially posteriorly accentuated lesion distribution pattern. 294/323 (91%) of CT-detected lesions were pleural. The LUS score showed an association with respiratory status and C-reactive protein; the correlation with the CT score was weak (Spearman's rho = 0.339, p < 0.001). High LUS scores on admission were also observed in patients who were discharged within 30 days. LUS during follow-up showed predominantly declining LUS scores. Conclusion: The LUS score reflected the clinical condition of the patients. No conclusion could be made on the prognostic value of the LUS, because of the low event rate. The LUS and CT score showed no sufficient correlation. This is probably due to different physical principles, which is why LUS could be of complementary value.
Language	English
Publishing date	2023-01-16
Publishing country	Germany
Document type	Journal Article
ZDB-ID	801064-x
ISSN	1438-8782 ; 1439-0914 ; 1431-4894 ; 0172-4614
ISSN (online)	1438-8782
ISSN	1439-0914 ; 1431-4894 ; 0172-4614
DOI	10.1055/a-2013-8045
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Book ; Online ; Thesis: Zeit-Raumanalyse des Einflusses von Umwelt und sozialen Faktoren auf den Ausbruch von Denguefieber im Zeitraum 2005-2009 in Guayaquil-Ecuador.

Castillo, Katty [Verfasser]

2012

Author's details	Katty Castillo
Keywords	Geowissenschaften ; Earth Sciences
Subject code	sg550
Language	German
Publisher	Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
Publishing place	Düsseldorf
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

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Article: Starkes Ost-West-Gefälle beim Typ-2-Diabetes - Regionale Prävalenz und Inzidenz des Diabetes mellitus in Deutschland

Jacobs, Esther / Castillo, Katty / Rathmann, Wolfgang

Kompendium Diabetes

2018 Volume 13, Issue -, Page(s) 6

Language	German
Document type	Article
ZDB-ID	2234717-3
ISSN	1861-8413
Database	Current Contents Medicine

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