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  1. Book ; Online ; E-Book: Ultraviolet astronomy and the quest for the origin of life

    Gómez de Castro, Ana I.

    2021  

    Author's details editor, Ana I. Gómez de Casto
    Keywords Life/Origin ; Ultraviolet astronomy
    Subject code 577
    Language English
    Size 1 online resource (xii, 163 pages) :, illustrations
    Publisher Elsevier
    Publishing place Amsterdam
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-12-819171-6 ; 0-12-819170-8 ; 978-0-12-819171-2 ; 978-0-12-819170-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Cultura contemporânea, identidades e sociabilidades: olhares sobre corpo, mídia e novas tecnologias

    Castro, Ana Lúcia de

    2010  

    Abstract: Este livro reúne a reflexão acerca das identidades na cultura contemporânea,realizada por pesquisadores que participaram do Seminário: Cultura contemporânea, corpo e novas tecnologias: diálogos em torno das identidades. O objetivo geral das reflexões ... ...

    Abstract Este livro reúne a reflexão acerca das identidades na cultura contemporânea,realizada por pesquisadores que participaram do Seminário: Cultura contemporânea, corpo e novas tecnologias: diálogos em torno das identidades. O objetivo geral das reflexões aqui apresentadas é tomar as inovações tecnológicas e seus impactos na vida cotidiana - particularmente na renovação e reinvenção de formas de sociabilidade e de construção de identidades - como uma chave privilegiada para o adentramento em meandros da cultura contemporânea. O corpo, suporte da cultura e território de construção de identidades, ao incorporar os recursos tecnológicos disponibilizados pelo mercado estético, como próteses, implantes, intervenções e tratamentos à base de laser, tem seu estatuto modificado e as fronteiras entre natureza e cultura passam a ser revistas em novos parâmetros, impondo novos desafios à reflexão sócio-antropológica. Este livro busca contribuir para este debate, somar um pequena centelha ao enorme esforço que se faz necessário no sentido de repensarmos as clássicas dicotomias conceituais que vem marcando a reflexão das ciências humanas e se demonstrando cada vez mais abaladas em seu alcance explicativo, frente às aceleradas transformações vivenciadas na vida social nesta modernidade do início do século XXI.
    Keywords Social sciences (General)
    Size 1 electronic resource (213 p.)
    Publisher SciELO Books - Editora UNESP
    Document type Book ; Online
    Note Portuguese ; Open Access
    HBZ-ID HT020089167
    ISBN 9788579830952 ; 8579830958
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Stenotrophomonas maltophilia

    Lopes Castro, Ana Gabriela / Araujo, Catarina

    Journal of cutaneous medicine and surgery

    2024  , Page(s) 12034754241229083

    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1361720-5
    ISSN 1615-7109 ; 1203-4754
    ISSN (online) 1615-7109
    ISSN 1203-4754
    DOI 10.1177/12034754241229083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4987: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Erythema Dyschromicum Perstans.

    Lopes Castro, Ana Gabriela / Araujo, Catarina

    Journal of cutaneous medicine and surgery

    2024  Volume 28, Issue 2, Page(s) 207

    MeSH term(s) Humans ; Erythema/etiology ; Skin Diseases, Genetic
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1361720-5
    ISSN 1615-7109 ; 1203-4754
    ISSN (online) 1615-7109
    ISSN 1203-4754
    DOI 10.1177/12034754241229084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4987: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Lupus-Like Syndrome in a Patient Treated With Adalimumab for Psoriasis.

    Lopes Castro, Ana Gabriela / Araujo, Catarina

    Journal of cutaneous medicine and surgery

    2024  Volume 28, Issue 2, Page(s) 211

    MeSH term(s) Humans ; Adalimumab/adverse effects ; Psoriasis/drug therapy ; Antibodies, Monoclonal ; Severity of Illness Index ; Treatment Outcome
    Chemical Substances Adalimumab (FYS6T7F842) ; Antibodies, Monoclonal
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1361720-5
    ISSN 1615-7109 ; 1203-4754
    ISSN (online) 1615-7109
    ISSN 1203-4754
    DOI 10.1177/12034754241227631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4987: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Strategies to reprogram anti-inflammatory macrophages towards pro-inflammatory macrophages to support cancer immunotherapies.

    Vizcaino Castro, Ana / Daemen, Toos / Oyarce, Cesar

    Immunology letters

    2024  Volume 267, Page(s) 106864

    Abstract: Tumor-associated myeloid cells, including macrophages and myeloid-derived suppressor cells, can be highly prevalent in solid tumors and play a significant role in the development of the tumor. Therefore, myeloid cells are being considered potential ... ...

    Abstract Tumor-associated myeloid cells, including macrophages and myeloid-derived suppressor cells, can be highly prevalent in solid tumors and play a significant role in the development of the tumor. Therefore, myeloid cells are being considered potential targets for cancer immunotherapies. In this review, we focused on strategies aimed at targeting tumor-associated macrophages (TAMs). Most strategies were studied preclinically but we also included a limited number of clinical studies based on these strategies. We describe possible underlying mechanisms and discuss future challenges and prospects.
    Language English
    Publishing date 2024-05-03
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 445150-8
    ISSN 1879-0542 ; 0165-2478
    ISSN (online) 1879-0542
    ISSN 0165-2478
    DOI 10.1016/j.imlet.2024.106864
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1512: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Auditory Dysfunction in Animal Models of Autism Spectrum Disorder.

    Castro, Ana Carolina / Monteiro, Patricia

    Frontiers in molecular neuroscience

    2022  Volume 15, Page(s) 845155

    Abstract: Autism spectrum disorder (ASD) is a neurodevelopmental disorder mainly characterized by social-communication impairments, repetitive behaviors and altered sensory perception. Auditory hypersensitivity is the most common sensory-perceptual abnormality in ... ...

    Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disorder mainly characterized by social-communication impairments, repetitive behaviors and altered sensory perception. Auditory hypersensitivity is the most common sensory-perceptual abnormality in ASD, however, its underlying neurobiological mechanisms remain elusive. Consistently with reports in ASD patients, animal models for ASD present sensory-perception alterations, including auditory processing impairments. Here we review the current knowledge regarding auditory dysfunction in rodent models of ASD, exploring both shared and distinct features among them, mechanistic and molecular underpinnings, and potential therapeutic approaches. Overall, auditory dysfunction in ASD models seems to arise from impaired central processing. Depending on the model, impairments may arise at different steps along the auditory pathway, from auditory brainstem up to the auditory cortex. Common defects found across models encompass atypical tonotopicity in different regions of the auditory pathway, temporal and spectral processing impairments and histological differences. Imbalance between excitation and inhibition (E/I imbalance) is one of the most well-supported mechanisms explaining the auditory phenotype in the ASD models studied so far and seems to be linked to alterations in GABAergic signaling. Such E/I imbalance may have a large impact on the development of the auditory pathway, influencing the establishment of connections responsible for normal sound processing.
    Language English
    Publishing date 2022-04-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2452967-9
    ISSN 1662-5099
    ISSN 1662-5099
    DOI 10.3389/fnmol.2022.845155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Eltrombopag Use in Children with Persistent and Chronic Primary Immune Thrombocytopenia in a Portuguese Pediatric Center.

    Lopes, Caroline / Castro, Ana / Maia, Raquel / Batalha, Sara / Kjöllerström, Paula

    Acta medica portuguesa

    2024  Volume 37, Issue 4, Page(s) 294–295

    MeSH term(s) Child ; Humans ; Purpura, Thrombocytopenic, Idiopathic ; Portugal ; Benzoates ; Hydrazines ; Chronic Disease ; Pyrazoles
    Chemical Substances eltrombopag (S56D65XJ9G) ; Benzoates ; Hydrazines ; Pyrazoles
    Language English
    Publishing date 2024-04-01
    Publishing country Portugal
    Document type Letter
    ZDB-ID 603078-6
    ISSN 1646-0758 ; 0870-399X
    ISSN (online) 1646-0758
    ISSN 0870-399X
    DOI 10.20344/amp.20532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2343: Show issues Location:
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  9. Article: Rituximab treatment in myasthenia gravis.

    Vesperinas-Castro, Ana / Cortés-Vicente, Elena

    Frontiers in neurology

    2023  Volume 14, Page(s) 1275533

    Abstract: Myasthenia gravis (MG) is a chronic autoimmune disease mediated by antibodies against post-synaptic proteins of the neuromuscular junction. Up to 10%-30% of patients are refractory to conventional treatments. For these patients, rituximab has been used ... ...

    Abstract Myasthenia gravis (MG) is a chronic autoimmune disease mediated by antibodies against post-synaptic proteins of the neuromuscular junction. Up to 10%-30% of patients are refractory to conventional treatments. For these patients, rituximab has been used off-label in the recent decades. Rituximab is a monoclonal antibody against the CD20 protein that leads to B cell depletion and to the synthesis of new antibody-secreting plasma cells. Although rituximab was created to treat B-cell lymphoma, its use has widely increased to treat autoimmune diseases. In MG, the benefit of rituximab treatment in MuSK-positive patients seems clear, but a high variability in the results of observational studies and even clinical trials has been reported for AChR-positive patients. Moreover, few evidence has been reported in seronegative MG and juvenile MG and some questions about regimen of administration or monitoring strategies, remains open. In this review, we intend to revise the available literature on this topic and resume the current evidence of effectiveness of Rituximab in MG, with special attention to results on every MG subtype, as well as the administration protocols, monitoring strategies and safety profile of the drug.
    Language English
    Publishing date 2023-10-02
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2023.1275533
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The Survival Rate of Posterior Immediate Implants in the Maxilla and Mandible: An Observational Retrospective Study of 158 Dental Implants.

    Mahesh, Lanka / Boquete Castro, Ana / Bhasin, Meenu T

    Cureus

    2023  Volume 15, Issue 9, Page(s) e45579

    Abstract: Background: Immediate implants are popular for the anterior sextants of the mouth and have shown a high success rate for the same. However, their installation in a fresh extraction socket in the posterior segments can also be beneficial to the patients ... ...

    Abstract Background: Immediate implants are popular for the anterior sextants of the mouth and have shown a high success rate for the same. However, their installation in a fresh extraction socket in the posterior segments can also be beneficial to the patients and limit the time for the patient to start the masticatory function. However, there have been contradicting results in different studies.
    Objectives: The primary objective of this retrospective study was to establish correlations between factors such as implant dimensions, implant categories, implant location, and various demographic parameters in relation to the longevity of implants. This investigation was conducted through a comprehensive clinical evaluation of immediate implants situated within the molar sections of both the upper (maxillary) and lower (mandibular) jaws.
    Methods: Between October 2015 and August 2022, a total of 158 implants were implanted, with 87 males and 71 females undergoing implant placement following tooth extraction. All implants were reinstated between 12 and 18 weeks after they were placed. Inferential statistics were performed using SPSS Statistics version 23 (IBM Corp. Released 2015. IBM SPSS Statistics for Windows, Version 23.0. Armonk, NY: IBM Corp.). The Chi-square test was employed to determine statistical significance (p=0.05) between survived and failed implants in relation to various study factors. Lastly, in order to measure the survival rate under different time periods after implant placement, the life table method and Kaplan-Meier survival rate analysis were used.
    Results: Success of implants was observed at 149 sites, whereas implant failure was seen at nine sites in total. From placement to loading, the implant failed at five sites, and the cumulative survival rate was found to be 96.83%, from loading to one year, implant failure was seen at three sites, and the cumulative survival rate was found to be 94.9%, from one to two years after loading implant failure was seen at only one site with cumulative survival rate to be 94.93%. From two to three years after loading, implant failure was not seen at any site.
    Conclusions: Regardless of implant size or insertion location, rapid implant implantation in fresh extraction sockets can result in predictable clinical outcomes.
    Language English
    Publishing date 2023-09-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.45579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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