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Article: Genotype-by-environment interactions drive the maintenance of genetic variation in a

Folio, Dorinda Marie / Gil, Jordi / Caudron, Arnaud / Labonne, Jacques

2021 Volume 14, Issue 11, Page(s) 2698–2711

Abstract: Allopatric gene pools can evolve in different directions through adaptive and nonadaptive processes and are therefore a source of intraspecific diversity. The connection of these previously isolated gene pools through human intervention can lead to ... ...

Abstract	Allopatric gene pools can evolve in different directions through adaptive and nonadaptive processes and are therefore a source of intraspecific diversity. The connection of these previously isolated gene pools through human intervention can lead to intraspecific diversity loss, through extirpation of native populations or hybridization. However, the mechanisms leading to these situations are not always explicitly documented and are thus rarely used to manage intraspecific diversity. In particular, genotype-by-environment (GxE) interactions can drive postzygotic reproductive isolation mechanisms that may result in a mosaic of diversity patterns, depending on the local environment. We test this hypothesis using a salmonid species (
Language	English
Publishing date	2021-10-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2405496-3
ISSN	1752-4563 ; 1752-4571
ISSN (online)	1752-4563
ISSN	1752-4571
DOI	10.1111/eva.13307
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Intérêt de l'élastographie pour la détection des métastases ganglionnaires de mélanome.

Caudron, A / Le Gloan, S / Lok, C

Annales de dermatologie et de venereologie

2014 Volume 141, Issue 11, Page(s) 694–696

Title translation	The value of elastography in detection of nodal melanoma metastasis.
MeSH term(s)	Biopsy, Needle/methods ; Elasticity Imaging Techniques/methods ; Elasticity Imaging Techniques/statistics & numerical data ; Humans ; Lymphatic Metastasis/diagnosis ; Magnetic Resonance Imaging/methods ; Melanoma/secondary ; Neoplasm Staging ; Palpation/methods ; Positron-Emission Tomography/methods ; Predictive Value of Tests ; Sensitivity and Specificity ; Ultrasonography, Doppler/methods
Language	French
Publishing date	2014-11
Publishing country	France
Document type	Letter
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
DOI	10.1016/j.annder.2014.06.010
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Article ; Online: La technologie RFID pour évaluer le franchissement piscicole d’une buse aménagée de grande dimension

CAUDRON, Arnaud / BERGÉ, Julien / RICHARD, Alexandre

Sciences, Eaux & Territoires, Vol 2020, Pp 1-

2020 Volume 7

Abstract: Les nombreux ouvrages et infrastructures installés sur les cours d’eau représentent des obstacles à la libre-circulation des poissons et perturbent leur cycle de vie. Aussi la mise en place de dispositifs de franchissement piscicole fonctionnels est ... ...

Abstract	Les nombreux ouvrages et infrastructures installés sur les cours d’eau représentent des obstacles à la libre-circulation des poissons et perturbent leur cycle de vie. Aussi la mise en place de dispositifs de franchissement piscicole fonctionnels est souvent nécessaire. Sur la Durolle, rivière salmonicole du Puy-de-Dôme, la technologie d’identification par radio-fréquence a été mobilisée avec succès pour évaluer le franchissement par la truite commune d’une buse de 104 mètres de long aménagée pour rétablir la circulation piscicole. Le suivi individuel des poissons sur une période de deux ans a également permis d’en savoir plus sur le comportement migratoire de l’espèce dans un petit cours d’eau comme la Durolle.
Keywords	biodiversite ; amenagement piscicole ; connectivite ; technologie ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350
Language	French
Publishing date	2020-06-01T00:00:00Z
Publisher	Institut national de recherche pour l’agriculture, l’alimentation et l’environnement (INRAE)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Multiple marking of otoliths of brown trout, Salmo trutta L., with alizarin redS to compare efficiency of stocking of three early life stages

CAUDRON, A / CHAMPIGNEULLE, A

Fisheries management and ecology. 2009 June, v. 16, no. 3

2009

Abstract: This study examined stocking with three early life stages of brown trout, Salmo trutta L., in the context of rehabilitating a native lineage. Experimental sections in five streams were stocked successively with three stages (I: unfed fry at the end of ... ...

Abstract	This study examined stocking with three early life stages of brown trout, Salmo trutta L., in the context of rehabilitating a native lineage. Experimental sections in five streams were stocked successively with three stages (I: unfed fry at the end of the reabsorption phase, II: fed fry measuring 2-3 cm and III: fed fry measuring 4-5 cm) derived from a hatchery stock bred from wild spawners. The three stages were distinguished by single or multiple fluoromarking of the otoliths with alizarin redS. The index of relative stocking efficiency was greater for stage II than for stage I in all sections and equivalent or greater than that for stage III. Stage II achieved significantly larger mean length and weight in autumn than stage III stockings.
Keywords	Salmo trutta ; autumn ; breeding stock ; hatcheries ; otoliths ; streams
Language	English
Dates of publication	2009-06
Size	p. 219-224.
Publisher	Blackwell Publishing Ltd
Publishing place	Oxford, UK
Document type	Article
ZDB-ID	1193882-1
ISSN	0969-997X
ISSN	0969-997X
DOI	10.1111/j.1365-2400.2009.00661.x
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Lymphœdème génital associé à une maladie de Crohn.

Garny de La Rivière, C / Caudron, A / Heyman, B / Lok, C

La Revue de medecine interne

2015 Volume 36, Issue 4, Page(s) 291–293

Abstract: Introduction: Crohn's disease is a chronic inflammatory intestinal pathology which can be associated to different extra-digestive manifestations. We reported a case of recurrent genital lymphedema leading to Crohn's disease diagnosis.: Case report: A ...

Title translation	Genital lymphedema associated with Crohn's disease.
Abstract	Introduction: Crohn's disease is a chronic inflammatory intestinal pathology which can be associated to different extra-digestive manifestations. We reported a case of recurrent genital lymphedema leading to Crohn's disease diagnosis. Case report: A 49-year-old man was referred for increased penis and scrotal volume, associated with recurrent febrile flare during the 10 previous years. Clinically, we noted an inflammatory penis and scrotum lymphedema. Clinical urological examination, and biological, bacteriological, computer-tomography examinations were negative. Metastatic Crohn's disease was diagnosed in association with concomitant severe terminal ileitis. Treatment with corticosteroids and azathioprine resulted in significant decrease of inflammatory genital lymphedema. Conclusion: Genital inflammatory lymphedema occurs during inflammatory, infectious, and tumor diseases. Some cases of metastatic genital lymphedema related to Crohn's disease are described, most often in children. Inflammatory genital lymphedema associated with gastrointestinal symptoms may suggest Crohn's disease.
MeSH term(s)	Crohn Disease/complications ; Genital Diseases, Male/etiology ; Humans ; Lymphedema/etiology ; Male ; Middle Aged ; Penile Diseases/etiology ; Scrotum
Language	French
Publishing date	2015-04
Publishing country	France
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	604679-4
ISSN	1768-3122 ; 0248-8663
ISSN (online)	1768-3122
ISSN	0248-8663
DOI	10.1016/j.revmed.2014.01.006
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Article: Actualités sur le syndrome de Sézary.

Caudron, A / Marie-Cardine, A / Bensussan, A / Bagot, M

Annales de dermatologie et de venereologie

2012 Volume 139, Issue 1, Page(s) 31–40

Abstract: Sézary syndrome (SS) represents 3% of cutaneous T-cell lymphomas (CTCL). It is an aggressive epidermotropic CTCL with a 5-year survival rate of 24%. According to EORTC (European organization for research and treatment of cancer), SS is defined by ... ...

Title translation	New developments in Sézary syndrome.
Abstract	Sézary syndrome (SS) represents 3% of cutaneous T-cell lymphomas (CTCL). It is an aggressive epidermotropic CTCL with a 5-year survival rate of 24%. According to EORTC (European organization for research and treatment of cancer), SS is defined by erythroderma, diffuse lymphadenopathy, atypical T lymphocytes (>1000/mm(3)), and the presence of a major blood, cutaneous and nodal T cell clone. A specific marker for atypical tumoral T lymphocytes known as Sézary cells was identified in 2001, namely KIR3DL2 (CD158k) receptor, which allows more specific diagnosis of SS; levels of this marker are highly correlated with the clinical course of the disease. In therapeutic terms, clinical trials are being conducted on new molecules that point towards an improved prognosis for this disease. We propose a review of Sézary syndrome, which is currently the subject of scientific papers concerning both physiopathology and therapeutics, with new prospects of targeted therapy.
MeSH term(s)	Animals ; Antibodies, Monoclonal/therapeutic use ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Biomarkers, Tumor/analysis ; Combined Modality Therapy ; Diphtheria Toxin/therapeutic use ; Disease Models, Animal ; Electrons/therapeutic use ; Hematopoietic Stem Cell Transplantation ; Histone Deacetylase Inhibitors/therapeutic use ; Humans ; Interferon-alpha/therapeutic use ; Interleukin-2/therapeutic use ; Mice ; Mice, SCID ; Molecular Targeted Therapy ; PUVA Therapy ; Photopheresis ; Receptors, KIR3DL2/analysis ; Receptors, KIR3DL2/genetics ; Recombinant Fusion Proteins/therapeutic use ; Sezary Syndrome/diagnosis ; Sezary Syndrome/drug therapy ; Sezary Syndrome/pathology ; Sezary Syndrome/therapy ; Skin Neoplasms/diagnosis ; Skin Neoplasms/drug therapy ; Skin Neoplasms/pathology ; Skin Neoplasms/therapy ; Tetrahydronaphthalenes/therapeutic use ; Therapies, Investigational
Chemical Substances	Antibodies, Monoclonal ; Antineoplastic Agents ; Biomarkers, Tumor ; Diphtheria Toxin ; Histone Deacetylase Inhibitors ; Interferon-alpha ; Interleukin-2 ; KIR3DL2 protein, human ; Receptors, KIR3DL2 ; Recombinant Fusion Proteins ; Tetrahydronaphthalenes ; denileukin diftitox (25E79B5CTM) ; bexarotene (A61RXM4375)
Language	French
Publishing date	2012-01
Publishing country	France
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
DOI	10.1016/j.annder.2011.09.188
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Article ; Online: Evidence of two contrasting brown trout Salmo trutta populations spatially separated in the River Borne (France) and shift in management towards conservation of the native lineage.

Caudron, A / Champigneulle, A / Guyomard, R

Journal of fish biology

2009 Volume 74, Issue 5, Page(s) 1070–1085

Abstract: A multidisciplinary study was made of brown trout Salmo trutta in the Borne River, a typical fast-flowing mountain stream in the Northern French Alps, in the geographical range of the Mediterranean lineages (ML). Information on (1) the proportion of ... ...

Abstract	A multidisciplinary study was made of brown trout Salmo trutta in the Borne River, a typical fast-flowing mountain stream in the Northern French Alps, in the geographical range of the Mediterranean lineages (ML). Information on (1) the proportion of stocked fluoro-marked fish in the angling harvest, (2) the introgression of introduced DNA microsatellite alleles into the native gene pool and (3) the demography of the population in situ in autumn revealed two contrasting populations separated by a physical barrier to upstream migration. A native S. trutta population (c. 10 000 adults) lives downstream of the barrier and is characterized by a large frequency of ML alleles (82-97%) and high densities (43-55 fish 100 m(-2)). This population is maintained predominantly by natural recruitment of juveniles (51-82%). In contrast, the upstream population is characterized by a large frequency of Atlantic lineage (AL) alleles (78-100%) and low densities (1-2 fish 100 m(-2)) and appears to be maintained by restocking (90-100%). The origins of these sharply contrasting populations appear to reflect isolation by an impassable barrier, catastrophic flooding, a downstream gradient in water quality, stocking and fishing pressure. The native downstream population has been resilient to large sudden floods and to intensive stockings of domesticated AL fish. The results of this study justify a shift in management towards conservation and rehabilitation of the native population.
MeSH term(s)	Alleles ; Animal Migration ; Animals ; Conservation of Natural Resources ; DNA, Mitochondrial/genetics ; France ; Gene Frequency ; Genetic Variation ; Genetics, Population ; Microsatellite Repeats ; Rivers ; Trout/genetics
Chemical Substances	DNA, Mitochondrial
Language	English
Publishing date	2009-04
Publishing country	England
Document type	Journal Article
ZDB-ID	410564-3
ISSN	1095-8649 ; 0022-1112
ISSN (online)	1095-8649
ISSN	0022-1112
DOI	10.1111/j.1095-8649.2008.02168.x
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Article ; Online: Multiple marking of otoliths of brown trout,Salmo truttaL., with alizarin redS to compare efficiency of stocking of three early life stages

Caudron, A. / Champigneulle, A.

2009

Abstract	This study examined stocking with three early life stages of brown trout, Salmo trutta L., in the context of rehabilitating a native lineage. Experimental sections in five streams were stocked successively with three stages (I: unfed fry at the end of the reabsorption phase, II: fed fry measuring 2–3 cm and III: fed fry measuring 4–5 cm) derived from a hatchery stock bred from wild spawners. The three stages were distinguished by single or multiple fluoromarking of the otoliths with alizarin redS. The index of relative stocking efficiency was greater for stage II than for stage I in all sections and equivalent or greater than that for stage III. Stage II achieved significantly larger mean length and weight in autumn than stage III stockings.
Language	English
Publisher	Wiley
Publishing country	de
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Developing collaborative research to improve effectiveness in biodiversity conservation practice

Caudron, A. / Vigier, L. / Champigneulle, A.

The journal of applied ecology

2012 Volume 49, Issue 4, Page(s) 753

Language	English
Document type	Article
ZDB-ID	410405-5
ISSN	0021-8901
Database	Current Contents Nutrition, Environment, Agriculture

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Article ; Online: Deliverability and efficacy of R-CHOP chemotherapy in very elderly patients with diffuse large B-cell lymphoma: an Australian retrospective analysis.

Millar, A / Ellis, M / Mollee, P / Cochrane, T / Fletcher, J / Caudron, A / Webster, B / Trotman, J

Internal medicine journal

2015 Volume 45, Issue 11, Page(s) 1147–1153

Abstract: Background: Elderly patients with diffuse large B-cell lymphoma (DLBCL) have an inferior prognosis, due in part to advanced age and pre-existing comorbidities, with reduced tolerability and deliverability of standard R-CHOP chemotherapy.: Aims: To ... ...

Abstract	Background: Elderly patients with diffuse large B-cell lymphoma (DLBCL) have an inferior prognosis, due in part to advanced age and pre-existing comorbidities, with reduced tolerability and deliverability of standard R-CHOP chemotherapy. Aims: To examine the deliverability, toxicity and efficacy of R-CHOP and the prevalence of the germinal and non-germinal phenotype DLBCL in an elderly Australian cohort. Methods: This retrospective analysis included patients ≥75 years diagnosed with DLBCL. Comprehensive chemotherapy and toxicity data were collected for patients treated with R-CHOP. Baseline demographics and chemotherapy characteristics were compared with progression-free (PFS) and overall survival (OS). Immunohistochemical staining identified the prevalence of the non-germinal centre (non-GCB) phenotype. Results: Of the 111 patients, 92 (83%) commenced R-CHOP with 26/92 (28%) receiving ≤4 cycles. Median average relative dose (ARD) was 0.80 (0.07-1.17). Median average relative dose intensity (ARDI) was 0.89 (0.33-1.18). Serious adverse events occurred in 77% of patients with ≥Gd3 adverse events in 74%. Overall response rate was 85%. Two-year PFS was 63% and OS 74%. ARD and performance status ≥2 were significant prognostic factors for PFS and OS but not ARDI. Non-GCB-phenotype was identified in 44/72 (61%) of patients with immunohistochemical data. Conclusion: Despite high response rates and respectable survival estimates, the absence of standard therapy in 17% of patients, and dose reductions and serious toxicity of R-CHOP in this Australian cohort highlights the need for the development of less toxic yet efficacious treatments for very elderly patients with DLBCL. The high prevalence of the non-GCB phenotype highlights the potential value of targeted biological therapy for this demographic.
MeSH term(s)	Aged ; Aged, 80 and over ; Antibodies, Monoclonal, Murine-Derived/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Australia/epidemiology ; Cyclophosphamide/administration & dosage ; Doxorubicin/administration & dosage ; Drug Delivery Systems/methods ; Female ; Humans ; Lymphoma, Large B-Cell, Diffuse/diagnosis ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/mortality ; Male ; Prednisone/administration & dosage ; Retrospective Studies ; Survival Rate/trends ; Treatment Outcome ; Vincristine/administration & dosage
Chemical Substances	Antibodies, Monoclonal, Murine-Derived ; R-CHOP protocol ; Vincristine (5J49Q6B70F) ; Doxorubicin (80168379AG) ; Cyclophosphamide (8N3DW7272P) ; Prednisone (VB0R961HZT)
Language	English
Publishing date	2015-11
Publishing country	Australia
Document type	Journal Article ; Multicenter Study
ZDB-ID	2045436-3
ISSN	1445-5994 ; 1444-0903
ISSN (online)	1445-5994
ISSN	1444-0903
DOI	10.1111/imj.12889
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