LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 7 of total 7

Search options

  1. Article: Antioxidant and photoprotective role of latex C-serum from

    Kerche, Leandra E / Carrara, Iriana M / Marinello, Poliana C / Cavalcante, Dalita G S M / Danna, Caroline S / Cecchini, Rubens / Cecchini, Alessandra L / Job, Aldo E

    Journal of toxicology and environmental health. Part A

    2023  Volume 86, Issue 22, Page(s) 846–858

    Abstract: It is known that UVB radiation induces several adverse skin alterations starting from simple photoaging to skin cancer. In addition, it was demonstrated that reactive oxygen species (ROS) were found to be related to cancer development and progression. ... ...

    Abstract It is known that UVB radiation induces several adverse skin alterations starting from simple photoaging to skin cancer. In addition, it was demonstrated that reactive oxygen species (ROS) were found to be related to cancer development and progression. The aim of study was to examine whether male hairless (SKH-1) mice (
    MeSH term(s) Animals ; Mice ; Antioxidants ; Ultraviolet Rays/adverse effects ; Hevea ; Latex ; Glutathione ; Carcinoma, Squamous Cell
    Chemical Substances Antioxidants ; Latex ; Glutathione (GAN16C9B8O)
    Language English
    Publishing date 2023-09-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1413345-3
    ISSN 1528-7394 ; 0098-4108 ; 1087-2620
    ISSN 1528-7394 ; 0098-4108 ; 1087-2620
    DOI 10.1080/15287394.2023.2255885
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1268: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Consequences of the exposure to bisphenol A in cell membrane models at the molecular level and hamster ovary cells viability.

    Maximino, Mateus D / Silva, Carla Y / Cavalcante, Dalita G S M / Martin, Cibely S / Job, Aldo E / Oliveira, Osvaldo N / Aléssio, Priscila

    Colloids and surfaces. B, Biointerfaces

    2021  Volume 203, Page(s) 111762

    Abstract: The inadequate disposal and the difficulty in its removal from water treatment systems have made the endocrine disruptor bisphenol A (BPA) a significant hazard for humans and animals. The molecular-level mechanisms of BPA action are not known in detail, ... ...

    Abstract The inadequate disposal and the difficulty in its removal from water treatment systems have made the endocrine disruptor bisphenol A (BPA) a significant hazard for humans and animals. The molecular-level mechanisms of BPA action are not known in detail, which calls for systematic investigations using cell membrane models. This paper shows that BPA affects Langmuir monolayers and giant unilamellar vesicles (GUVs) of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) used as membrane models, in a concentration-dependent manner and with effects that depend on BPA aggregation. BPA increases DPPC monolayer fluidity in surface pressure isotherms upon interacting with the headgroups through hydrogen bonding, according to polarization-modulated infrared reflection absorption spectroscopy (PM-IRRAS). In DPPC GUVs, BPA induced wrinkling and distortion in the spherical shape of the vesicles, but this was only observed for fresh solutions where it is not aggregated. BPA also decreased the viability of hamster ovary cells (CHO) in in vitro experiments. In contrast, aged, aggregated BPA solutions did not affect the GUVs and even increased CHO viability. These results may be rationalized in terms of size-dependent effects of BPA, which may be relevant for its endocrine-disrupting effects.
    MeSH term(s) Aged ; Animals ; Benzhydryl Compounds ; Cell Membrane ; Cricetinae ; Humans ; Phenols ; Spectrophotometry, Infrared
    Chemical Substances Benzhydryl Compounds ; Phenols ; bisphenol A (MLT3645I99)
    Language English
    Publishing date 2021-04-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500523-9
    ISSN 1873-4367 ; 0927-7765
    ISSN (online) 1873-4367
    ISSN 0927-7765
    DOI 10.1016/j.colsurfb.2021.111762
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Red-emitting heteroleptic iridium(III) complexes: photophysical and cell labeling study.

    Canisares, Felipe S M / Mutti, Alessandra M G / Santana, Edy F / Oliveira, Vytor C / Cavalcante, Dalita G S M / Job, Aldo E / Pires, Ana M / Lima, Sergio A M

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

    2022  Volume 21, Issue 6, Page(s) 1077–1090

    Abstract: Two red-emitting heteroleptic iridium(III) complexes (Ir-p and Ir-q) were synthesized and their photophysical and biological properties were analyzed. After their structures have been confirmed by several techniques, such ... ...

    Abstract Two red-emitting heteroleptic iridium(III) complexes (Ir-p and Ir-q) were synthesized and their photophysical and biological properties were analyzed. After their structures have been confirmed by several techniques, such as
    MeSH term(s) Iridium/chemistry ; Luminescence ; Molecular Structure ; Organometallic Compounds/chemistry ; Spectroscopy, Fourier Transform Infrared
    Chemical Substances Organometallic Compounds ; Iridium (44448S9773)
    Language English
    Publishing date 2022-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2072584-X
    ISSN 1474-9092 ; 1474-905X
    ISSN (online) 1474-9092
    ISSN 1474-905X
    DOI 10.1007/s43630-022-00200-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Green synthesis of colloidal gold nanoparticles using latex from

    Santos, Natália M / Gomes, Andressa S / Cavalcante, Dalita G S M / Santos, Luis F / Teixeira, Silvio R / Cabrera, Flávio C / Job, Aldo Eloizo

    IET nanobiotechnology

    2019  Volume 13, Issue 3, Page(s) 307–315

    Abstract: Latex extracted ... ...

    Abstract Latex extracted from
    MeSH term(s) Animals ; Apoptosis ; CHO Cells ; Carcinogenicity Tests ; Cell Survival ; Colloids/chemistry ; Cricetinae ; Cricetulus ; DNA Damage ; Gold/chemistry ; Green Chemistry Technology ; Hevea/chemistry ; Hydrogen-Ion Concentration ; Latex/chemistry ; Metal Nanoparticles/chemistry ; Mutagenicity Tests ; Temperature
    Chemical Substances Colloids ; Latex ; Gold (7440-57-5)
    Language English
    Publishing date 2019-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2264529-9
    ISSN 1751-875X ; 1751-8741
    ISSN (online) 1751-875X
    ISSN 1751-8741
    DOI 10.1049/iet-nbt.2018.5225
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Composites Produced from Natural Rubber and Chrome-Tanned Leather Wastes: Evaluation of their In Vitro Toxicological Effects for Application in Footwear and Textile Industries

    Cavalcante, DalitaG. S. M / Andressa S. Gomes / Renivaldo J. Santos / Leandra Ernst Kerche-Silva / Caroline Silva Danna / Eidi Yoshihara / Aldo E. Job

    Journal of polymers and the environment. 2018 Mar., v. 26, no. 3

    2018  

    Abstract: A new composite has been developed from natural rubber and chrome-tanned leather waste for use in footwear and textile industries. The contribution of this material to environmental quality and sustained development should be highligh because chrome ... ...

    Abstract A new composite has been developed from natural rubber and chrome-tanned leather waste for use in footwear and textile industries. The contribution of this material to environmental quality and sustained development should be highligh because chrome tanned leather wastes, a major environmental problem, can be recycled. However, the safety of this new material for human use is questionable, as it is already well reported in the literature that chromium, particularly in its hexavalent oxidation state, can be genotoxic and carcinogenic to living beings. Thus, the aim of this study was to evaluate in vitro biocompatibility of this composite material for possible use in the footwear and textile industries, through cytotoxicity, cell adhesion, and genotoxicity tests. Inductively coupled plasma optical emission spectrometry (ICP-OES) was used to measure both concentrations of total and hexavalent chromium. Based on the findings, it was concluded that the composite exhibits low levels of cytotoxicity and genotoxicity, and possesses favorable properties for initial cell adhesion. Furthermore, it was verified that the composites released low concentrations of chromium and that the predominant species released would be trivalent chromium. The results of the present study open the possibility of the incorporation of solid residues of tanned leather into chromium without necessarily the chromium contained in these residues influences the toxicity and genotoxicity of this new material.
    Keywords atomic absorption spectrometry ; biocompatibility ; cell adhesion ; chromium ; composite materials ; cytotoxicity ; environmental quality ; genotoxicity ; genotoxicity tests ; humans ; leather ; mutagens ; oxidation ; rubber ; textile industry ; wastes
    Language English
    Dates of publication 2018-03
    Size p. 980-988.
    Publishing place Springer US
    Document type Article
    ZDB-ID 2017207-2
    ISSN 1572-8919 ; 1572-8900 ; 1566-2543
    ISSN (online) 1572-8919 ; 1572-8900
    ISSN 1566-2543
    DOI 10.1007/s10924-017-1002-9
    Database NAL-Catalogue (AGRICOLA)

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Protective effects of bark ethanolic extract from Spondias dulcis Forst F. against DNA damage induced by benzo[a]pyrene and cyclophosphamide.

    Araujo, Caroline de S / Brito, Lorrane D / Tarifa, Marina O / Silva, Nayara J Farah da / Rodrigues, Karoline S / Cavalcante, Dalita G S M / Gomes, Andressa S / Zocoler, Marcos A / Yoshihara, Eidi / Camparoto, Marjori L / Job, Aldo E / Kerche, Leandra E

    Genetics and molecular biology

    2019  Volume 42, Issue 3, Page(s) 643–654

    Abstract: This study evaluated the genotoxicity, mutagenicity, antigenotoxicity, and antimutagenicity effects on biochemical parameters of oxidative stress of the Spondias dulcis bark ethanolic extract on mice. The extract was evaluated in the doses of 500, 1000, ... ...

    Abstract This study evaluated the genotoxicity, mutagenicity, antigenotoxicity, and antimutagenicity effects on biochemical parameters of oxidative stress of the Spondias dulcis bark ethanolic extract on mice. The extract was evaluated in the doses of 500, 1000, and 1500 mg/kg bw via gavage. To evaluate the protective effects of the extract, benzo[a]pyrene (B[a]P) and cyclophosphamide (CP) were chosen as DNA damage inducers. Genotoxicity and antigenotoxicity were evaluated by the comet assay. Cytotoxicity, mutagenicity, and antimutagenicity were evaluated by the micronucleus test in bone marrow and peripheral blood. The biochemical parameters of oxidative stress were evaluated by the quantification of catalase activity (CAT) and reduced glutathione (GSH) in total blood, liver and kidney, and malondialdehyde (MDA), in liver and kidney. No genotoxic, cytotoxic, or mutagenic effect was found on mice exposed to the extract. The extract depleted the number of damaged nucleoids in total blood and the number of micronucleus (MN) in both cell types. The extract was able to increase CAT activity and GSH levels and decrease MDA levels after treatment with B[a]P and CP. The results indicate that the S. dulcis extract has potential to be used as preventive compound against DNA damage caused by CP and B[a]P.
    Language English
    Publishing date 2019-11-14
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1445712-x
    ISSN 1678-4685 ; 1415-4757
    ISSN (online) 1678-4685
    ISSN 1415-4757
    DOI 10.1590/1678-4685-GMB-2018-0038
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3079: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Cytotoxic, biochemical and genotoxic effects of biodiesel produced by different routes on ZFL cell line.

    Cavalcante, Dalita G S M / da Silva, Natara D G / Marcarini, Juliana Cristina / Mantovani, Mário Sérgio / Marin-Morales, Maria A / Martinez, Cláudia B R

    Toxicology in vitro : an international journal published in association with BIBRA

    2014  Volume 28, Issue 6, Page(s) 1117–1125

    Abstract: Transesterification has proved to be the best option for obtaining biodiesel and, depending on the type of alcohol used in the reaction, the type of biodiesel may be methyl ester or ethyl ester. Leaking biodiesel can reach water bodies, contaminating ... ...

    Abstract Transesterification has proved to be the best option for obtaining biodiesel and, depending on the type of alcohol used in the reaction, the type of biodiesel may be methyl ester or ethyl ester. Leaking biodiesel can reach water bodies, contaminating aquatic organisms, particularly fish. The objective of this study was to determine whether the soluble fraction of biodiesel (Bd), produced by both the ethylic (BdEt) and methylic (BdMt) routes, can cause cytotoxic, biochemical and genotoxic alterations in the hepatocyte cell line of Danio rerio (ZFL). The metabolic activity of the cell was quantified by the MTT reduction method, while genotoxic damage was analyzed by the comet assay with the addition of specific endonucleases. The production of reactive oxygen species (ROS) and antioxidant/biotransformation enzymes activity also were determined. The results indicate that both Bd increased ROS production, glutathione S-transferase activity and the occurrence of DNA damage. BdMt showed higher cytotoxicity than BdEt, and also caused oxidative damage to the DNA. In general, both Bd appear to be stressors for the cells, causing cytotoxic, biochemical and genetic alterations in ZFL cells, but the type and intensity of the changes found appear to be dependent on the biodiesel production route.
    MeSH term(s) Animals ; Biofuels/toxicity ; Cell Line ; Cell Survival/drug effects ; Comet Assay ; DNA Damage ; Glutathione Transferase/metabolism ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Mutagens/toxicity ; Reactive Oxygen Species/metabolism ; Zebrafish
    Chemical Substances Biofuels ; Mutagens ; Reactive Oxygen Species ; Glutathione Transferase (EC 2.5.1.18)
    Language English
    Publishing date 2014-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639064-x
    ISSN 1879-3177 ; 0887-2333
    ISSN (online) 1879-3177
    ISSN 0887-2333
    DOI 10.1016/j.tiv.2014.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2223: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top