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  1. Article ; Online: Agent Based Modelling for Simulating the Interregional Patient Mobility in Italy.

    Pecoraro, Fabrizio / Accordino, Filippo / Cecconi, Federico / Paolucci, Mario

    Studies in health technology and informatics

    2023  Volume 302, Page(s) 297–301

    Abstract: Patient mobility is considered one of the main concerns for policy-makers as it impacts financial sustainability of regional health systems due to the high percentage of patients accessing care services in other regions. For a better understanding of ... ...

    Abstract Patient mobility is considered one of the main concerns for policy-makers as it impacts financial sustainability of regional health systems due to the high percentage of patients accessing care services in other regions. For a better understanding of this phenomenon, it is necessary to define a behavioral model able to represent the patient-system interaction. In this paper we adopted the Agent-Based Modelling (ABM) approach with the aim of simulating patient flow across regions and determining which are the main factors influencing it. This may provide a new insight for policy makers to capture which are the main factors influencing mobility and actions that may contribute to contain this phenomenon.
    MeSH term(s) Humans ; Mobility Limitation ; Government Programs ; Patients ; Systems Analysis ; Italy
    Language English
    Publishing date 2023-05-19
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI230122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Functional balance at rest of hemispheric homologs assessed via normalized compression distance.

    Pascarella, Annalisa / Bruni, Vittoria / Armonaite, Karolina / Porcaro, Camillo / Conti, Livio / Cecconi, Federico / Paulon, Luca / Vitulano, Domenico / Tecchio, Franca

    Frontiers in neuroscience

    2024  Volume 17, Page(s) 1261701

    Abstract: Introduction: The formation and functioning of neural networks hinge critically on the balance between structurally homologous areas in the hemispheres. This balance, reflecting their physiological relationship, is fundamental for learning processes. In ...

    Abstract Introduction: The formation and functioning of neural networks hinge critically on the balance between structurally homologous areas in the hemispheres. This balance, reflecting their physiological relationship, is fundamental for learning processes. In our study, we explore this functional homology in the resting state, employing a complexity measure that accounts for the temporal patterns in neurodynamics.
    Methods: We used Normalized Compression Distance (NCD) to assess the similarity over time, neurodynamics, of the somatosensory areas associated with hand perception (S1). This assessment was conducted using magnetoencephalography (MEG) in conjunction with Functional Source Separation (FSS). Our primary hypothesis posited that neurodynamic similarity would be more pronounced within individual subjects than across different individuals. Additionally, we investigated whether this similarity is influenced by hemisphere or age at a population level.
    Results: Our findings validate the hypothesis, indicating that NCD is a robust tool for capturing balanced functional homology between hemispheric regions. Notably, we observed a higher degree of neurodynamic similarity in the population within the left hemisphere compared to the right. Also, we found that intra-subject functional homology displayed greater variability in older individuals than in younger ones.
    Discussion: Our approach could be instrumental in investigating chronic neurological conditions marked by imbalances in brain activity, such as depression, addiction, fatigue, and epilepsy. It holds potential for aiding in the development of new therapeutic strategies tailored to these complex conditions, though further research is needed to fully realize this potential.
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2023.1261701
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Opinion dynamics and consensus formation in a Deffuant model with extremists and moderates

    Marconi, Luca / Cecconi, Federico

    2020  

    Abstract: Among the different disciplines in the social, behavioral and economic sciences, a fundamental class of problems is related to the prediction of the final state of the presence of individual opinions in a large population. The main aspects investigated ... ...

    Abstract Among the different disciplines in the social, behavioral and economic sciences, a fundamental class of problems is related to the prediction of the final state of the presence of individual opinions in a large population. The main aspects investigated in the opinion dynamics are related to the possibility of reaching an agreement and the time needed. In general a consensus model allows to understand if a set of interacting agents can reach a consensus when choosing among several options: political vote, opinions, cultural features are well-known examples of them. Opinion dynamics models then can be seen as a sub-set of consensus models, when the options to choose from are opinions and the possible social consensus to be reached is the opinion agreement. Moreover, in large populations it is intuitive to find moderates, whose opinion is not at the extremes of the political opinion spectrum. Due to the wide range of their empirical presence, the study of their influence in the opinion dynamics processes is very important to enhance the comprehension of the political opinions evolution in large populations. The Deffuant model is aimed at studying consensus formation assuming that the opinion distribution of a population evolves via a sequence of random pairwise encounters. In this work we strive to extend the classical Deffuant model with the presence of moderates in addition to the extremists, so as to study the emergence of consensus with different initial configurations of opinions and parameters. Therefore, we assess the role and the importance of the moderates for the appearance of consensus in the opinion dynamics processes within in large populations. We show that the population behavior is affected by the presence of a critical number of moderates, in specific configurations of the model parameters: when this threshold is reached the opinions in the population progressively converge
    Keywords Physics - Physics and Society
    Subject code 612
    Publishing date 2020-10-04
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book: Special Issue on advances in computational economics and econometrics

    Cecconi, Federico / Cerulli, Giovanni / Miceli, Maria Augusta

    (International journal of computational economics and econometrics ; volume 5, no3., 2015)

    2015  

    Title variant Advances in computational economics and econometrics
    Author's details guest editors/herausgegeben von Federico Cecconi (ISTC-CNR, Italy), Giovanni Cerulli (IRCrES-CNR, Italy) and Maria Augusta Miceli (Sapienza University of Rome, Italy)
    Series title International journal of computational economics and econometrics ; volume 5, no3., 2015
    Language English
    Size Seite 211-360, Illustrationen
    Publisher Inderscience Enterprises
    Publishing place Genève
    Document type Book
    Note Enthält 8 Beiträge
    Database ECONomics Information System

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  5. Article: Effects on Corticospinal Tract Homology of Faremus Personalized Neuromodulation Relieving Fatigue in Multiple Sclerosis: A Proof-of-Concept Study.

    Bertoli, Massimo / Tataranni, Angela / Porziani, Susanna / Pasqualetti, Patrizio / Gianni, Eugenia / Grifoni, Joy / L'Abbate, Teresa / Armonaite, Karolina / Conti, Livio / Cancelli, Andrea / Cottone, Carlo / Marinozzi, Franco / Bini, Fabiano / Cecconi, Federico / Tecchio, Franca

    Brain sciences

    2023  Volume 13, Issue 4

    Abstract: Objectives: Fatigue in multiple sclerosis (MS) is a frequent and invalidating symptom, which can be relieved by non-invasive neuromodulation, which presents only negligible side effects. A 5-day transcranial direct-current stimulation, 15 min per day, ... ...

    Abstract Objectives: Fatigue in multiple sclerosis (MS) is a frequent and invalidating symptom, which can be relieved by non-invasive neuromodulation, which presents only negligible side effects. A 5-day transcranial direct-current stimulation, 15 min per day, anodically targeting the somatosensory representation of the whole body against a larger occipital cathode was efficacious against MS fatigue (fatigue relief in multiple sclerosis, Faremus treatment). The present proof-of-concept study tested the working hypothesis that Faremus S1 neuromodulation modifies the homology of the dominant and non-dominant corticospinal (CST) circuit recruitment.
    Methods: CST homology was assessed via the Fréchet distance between the morphologies of motor potentials (MEPs) evoked by transcranial magnetic stimulation in the homologous left- and right-hand muscles of 10 fatigued MS patients before and after Faremus.
    Results: In the absence of any change in MEP features either as differences between the two body sides or as an effect of the treatment, Faremus changed in physiological direction the CST's homology. Faremus effects on homology were more evident than recruitment changes within the dominant and non-dominant sides.
    Conclusions: The Faremus-related CST changes extend the relevance of the balance between hemispheric homologs to the homology between body sides. With this work, we contribute to the development of new network-sensitive measures that can provide new insights into the mechanisms of neuronal functional patterning underlying relevant symptoms.
    Language English
    Publishing date 2023-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13040574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: On the Homology of the Dominant and Non-Dominant Corticospinal Tracts: A Novel Neurophysiological Assessment.

    Pagliara, Maria Rita / Cecconi, Federico / Pasqualetti, Patrizio / Bertoli, Massimo / Armonaite, Karolina / Gianni, Eugenia / Grifoni, Joy / L'Abbate, Teresa / Marinozzi, Franco / Conti, Livio / Paulon, Luca / Uncini, Antonino / Zappasodi, Filippo / Tecchio, Franca

    Brain sciences

    2023  Volume 13, Issue 2

    Abstract: Objectives: The homology of hemispheric cortical areas plays a crucial role in brain functionality. Here, we extend this concept to the homology of the dominant and non-dominant hemi-bodies, investigating the relationship of the two corticospinal tracts ...

    Abstract Objectives: The homology of hemispheric cortical areas plays a crucial role in brain functionality. Here, we extend this concept to the homology of the dominant and non-dominant hemi-bodies, investigating the relationship of the two corticospinal tracts (CSTs). The evoked responses provide an estimate of the number of in-phase recruitments via their amplitude as a suitable indicator of the neuronal projections' integrity. An innovative concept derived from experience in the somatosensory system is that their morphology reflects the recruitment pattern of the whole circuit.
    Methods: CST homology was assessed via the Fréchet distance between the morphologies of motor-evoked potentials (MEPs) using a transcranial magnetic stimulation (TMS) in the homologous left- and right-hand first dorsal interosseous muscles of 40 healthy volunteers (HVs). We tested the working hypothesis that the inter-side Fréchet distance was higher than the two intra-side distances.
    Results: In addition to a clear confirmation of the working hypothesis (
    Conclusions: The newly introduced measure of circuit recruitment patterning represents a potential benchmark for the evaluation of inter-lateral mechanisms expressing the relationship between homologous hemilateral structures subtending learning and suggests that variability in recruitment patterning physiologically increases in circuits expressing greater functionality.
    Language English
    Publishing date 2023-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13020278
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  7. Article: Sequential pairwise trading

    Miceli, Maria-Augusta / Cecconi, Federico / Cerulli, Giovanni

    International journal of computational economics and econometrics Vol. 6, No. 1 , p. 13-43

    convergence and welfare implications

    2016  Volume 6, Issue 1, Page(s) 13–43

    Author's details Maria-Augusta Miceli, Federico Cecconi, Giovanni Cerulli
    Keywords pairwise exchange ; tatônnement ; rationing ; mispricing ; walrasian equilibrium ; sequential equilibrium ; auctioneer ; price overreaction ; wealth divide ; ABM ; agent-based-models
    Language English
    Publisher Inderscience Enterprises
    Publishing place Genève [u.a.]
    Document type Article
    ZDB-ID 2550146X
    ISSN 1757-1170
    Database ECONomics Information System

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  8. Article ; Online: The Morphology of Somatosensory Evoked Potentials During Middle Cerebral Artery Aneurysm Clipping (MoSAC): A Pilot Study.

    Tecchio, Franca / Cecconi, Federico / Colamartino, Elisabetta / Padalino, Matteo / Valci, Luca / Reinert, Michael

    Clinical EEG and neuroscience

    2019  Volume 51, Issue 2, Page(s) 130–136

    Abstract: Somatosensory evoked potential (SEP) monitoring is a standard tool during clipping of aneurysms of the middle cerebral artery (MCA), and the parameter used to detect a state of cortical ischemia is amplitude. We think that the sensitivity of SEP can ... ...

    Abstract Somatosensory evoked potential (SEP) monitoring is a standard tool during clipping of aneurysms of the middle cerebral artery (MCA), and the parameter used to detect a state of cortical ischemia is amplitude. We think that the sensitivity of SEP can however be improved by using other parameters. Our study moves in this direction via SEP morphology. In this pilot preliminary study, involving a small sample without postoperative neurological deficit, we aimed at investigating the value of SEP morphology (in the 15- to 35-ms time frame), in comparison with SEP amplitude (N20 peak-to-peak), as a measure of sensitivity to blood flow reduction. The changes in the SEP morphology of 16 patients undergoing clipping of an unruptured MCA aneurysm was studied. We applied the Morph-Fréchet index for each recorded SEP (at 30-second intervals), quantifying the pattern shape change with regard to the average SEP recorded after dura opening (baseline). We also compared 3 measurements of the SEP morphology, without and with GARCH-derived filter. Filtered Morph-Fréchet never exceeded the individual's "normality" range in baseline but did so in 81% of the risk phase on average across the 16 subjects, which is more than that for amplitude (36%,
    MeSH term(s) Adult ; Brain/physiopathology ; Brain Ischemia/physiopathology ; Electroencephalography/methods ; Evoked Potentials, Somatosensory/physiology ; Female ; Humans ; Intracranial Aneurysm/physiopathology ; Male ; Middle Aged ; Monitoring, Intraoperative/methods ; Monitoring, Physiologic/methods ; Pilot Projects
    Language English
    Publishing date 2019-09-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2140201-2
    ISSN 2169-5202 ; 0009-9155 ; 1550-0594
    ISSN (online) 2169-5202
    ISSN 0009-9155 ; 1550-0594
    DOI 10.1177/1550059419874942
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Book ; Online: A Policy-oriented Agent-based Model of Recruitment into Organized Crime

    Campedelli, Gian Maria / Calderoni, Francesco / Paolucci, Mario / Comunale, Tommaso / Vilone, Daniele / Cecconi, Federico / Andrighetto, Giulia

    2020  

    Abstract: Criminal organizations exploit their presence on territories and local communities to recruit new workforce in order to carry out their criminal activities and business. The ability to attract individuals is crucial for maintaining power and control over ...

    Abstract Criminal organizations exploit their presence on territories and local communities to recruit new workforce in order to carry out their criminal activities and business. The ability to attract individuals is crucial for maintaining power and control over the territories in which these groups are settled. This study proposes the formalization, development and analysis of an agent-based model (ABM) that simulates a neighborhood of Palermo (Sicily) with the aim to understand the pathways that lead individuals to recruitment into organized crime groups (OCGs). Using empirical data on social, economic and criminal conditions of the area under analysis, we use a multi-layer network approach to simulate this scenario. As the final goal, we test different policies to counter recruitment into OCGs. These scenarios are based on two different dimensions of prevention and intervention: (i) primary and secondary socialization and (ii) law enforcement targeting strategies.

    Comment: 15 pages, 2 figures. Paper accepted and in press for the Proceedings of the 2019 Social Simulation Conference (Mainz, Germany)
    Keywords Computer Science - Multiagent Systems ; Computer Science - Computers and Society ; Computer Science - Social and Information Networks ; Nonlinear Sciences - Chaotic Dynamics
    Subject code 360
    Publishing date 2020-01-10
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Describing economic agent-based models

    Bouchaud, Jean-Philippe / Cecconi, Federico / Cincotti, Silvano / Dawid, Herbert / Wolf, Sarah

    Complexity economics , No. 2 , p. 63-74

    Dahlem ABM documentation guidelines

    2013  , Issue 2, Page(s) 63–74

    Author's details Sarah Wolf; Jean-Philippe Bouchaud; Federico Cecconi; Silvano Cincotti; Herbert Dawid
    Keywords Agentenbasierte Modellierung ; Theorie
    Language English
    Publisher Baltzer
    Publishing place Berlin
    Document type Article
    Note ABM = Agent-based Model
    ZDB-ID 2763843-1
    ISSN 2210-4275
    Database ECONomics Information System

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