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  1. Article ; Online: Application of the Kvaal method to CBCT reconstructed panoramic images for age estimation.

    Çelik, Hatice / Kılıçarslan, Mehmet Ali / Boyacioglu, Hatice / Bilecen, Burak

    Forensic science, medicine, and pathology

    2024  

    Abstract: As the teeth are more durable than other parts of the skeleton, they provide valuable data for age estimation. Age estimation from adult teeth is mainly based on secondary dentin production. The present study aimed to devise a regression formula for age ... ...

    Abstract As the teeth are more durable than other parts of the skeleton, they provide valuable data for age estimation. Age estimation from adult teeth is mainly based on secondary dentin production. The present study aimed to devise a regression formula for age estimation specific to the Anatolian population using the Kvaal method on CBCT reconstructed panoramic images. In total, 201 individuals aged between 20 and 69 were divided into two groups: data from the study group (n = 101) were used to create the regression formulae, and data from the control group (n = 100) were used to test the formulae. Pearson's correlation coefficients and linear regression analyses were performed. Maxillary teeth provided more accurate age estimates than mandibular teeth. The regression formulae derived in this study are found to be statistically applicable and reasonably accurate. However, these results should be interpreted with caution.
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2195904-3
    ISSN 1556-2891 ; 1547-769X
    ISSN (online) 1556-2891
    ISSN 1547-769X
    DOI 10.1007/s12024-024-00783-x
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  2. Article ; Online: Pediatric hemophilia patient: Successful desensitization for drug-induced fixed urticaria with prothrombin complex concentrate.

    Çelik, Hatice Irmak / Akay, Eray / Emeksiz, Zeynep Şengül / Işık, Melek / Yaralı, Hüsniye Neşe / Mısırlıoğlu, Emine Dibek

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2024  Volume 35, Issue 3, Page(s) e14105

    MeSH term(s) Humans ; Child ; Hemophilia A/drug therapy ; Blood Coagulation Factors/therapeutic use
    Chemical Substances prothrombin complex concentrates (37224-63-8) ; Blood Coagulation Factors
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.14105
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    Zs.A 3096: Show issues Location:
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  3. Article ; Online: Maternal irisin level in last trimester isolated intrauterine growth-restriction.

    Erol Koc, Esin Merve / Çelik, Hatice Kansu / Sahin, Dilek

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2020  Volume 35, Issue 14, Page(s) 2635–2641

    Abstract: Purpose: Intrauterine Growth Restriction (IUGR) is the inability of the fetus to achieve the biologically accessible growth potential. Irisin is a recently discovered adipomyokine with a crucial role in energy metabolism. Our current study aimed to ... ...

    Abstract Purpose: Intrauterine Growth Restriction (IUGR) is the inability of the fetus to achieve the biologically accessible growth potential. Irisin is a recently discovered adipomyokine with a crucial role in energy metabolism. Our current study aimed to investigate the relationship between the isolated IUGR in the third trimester and maternal serum irisin level.
    Materials and methods: This prospective case-control study included total 137 pregnant women who were between the 24th and 39th gestational weeks and who applied to the University of Health Sciences, Ankara Zekai Tahir Burak Women's Health Training and Research Center, between 2016 October-2017 May. The Study Group consisted of 68 pregnant women who were diagnosed with Isolated IUGR with Estimated Fetal Weight (EFW) <10th percentile. The Control Group consisted of 69 low-risk uncomplicated pregnant women, matched with the Study Group in terms of gestational week, and with EFW between 10th and 90th percentiles. Demographic data, clinical findings, fetal Doppler parameters, and obstetric-neonatal outcomes were evaluated. Maternal serum irisin levels were measured by ELISA (Enzyme-Linked Immunosorbent Assay) Method and compared between the groups.
    Results: Maternal serum irisin level was found to be significantly lower in IUGR Group as compared to the Control (3.83 ng/ml vs. 4.78 ng/ml,
    Conclusion: Low level of maternal serum irisin in pregnancies with isolated IUGR was consistent with the role of irisin in metabolic pathways and with the increased risk of metabolic diseases in the future life of IUGR fetuses and their mothers.
    MeSH term(s) Case-Control Studies ; Female ; Fetal Growth Retardation/diagnosis ; Fetal Weight ; Fibronectins/blood ; Humans ; Infant, Newborn ; Pregnancy ; Pregnancy Trimester, Third
    Chemical Substances FNDC5 protein, human ; Fibronectins
    Language English
    Publishing date 2020-07-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2020.1793315
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    Zs.A 3510: Show issues Location:
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  4. Article ; Online: Sliced vs crushed cartilage for camouflage: long-term graft survival and histological outcomes.

    Ergun, Onur / Çelik, Hatice / Zeybek, Naciye Dilara / Karakaya, Jale

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2021  Volume 279, Issue 6, Page(s) 2943–2950

    Abstract: Purpose: In this study, we proposed a "sliced-partial thickness cartilage graft" for nasal contour restoration purposes and compared the long-term graft survival and histological changes of sliced, crushed, and intact cartilage grafts.: Methods: ... ...

    Abstract Purpose: In this study, we proposed a "sliced-partial thickness cartilage graft" for nasal contour restoration purposes and compared the long-term graft survival and histological changes of sliced, crushed, and intact cartilage grafts.
    Methods: Nasal septal and auricular cartilage grafts were harvested from 8 rabbits. Sliced, crushed, or intact cartilage grafts were measured in thickness with a micrometer and re-implanted. 4 months later, specimens were histologically evaluated and thickness were measured.
    Results: Both nasal septal and auricular crushed cartilage lost significantly more chondrocytes than sliced samples together with fibrosis, multiple fracture lines, and even ossification. Sliced and intact cartilages were histologically similar except sliced cartilage had some minor changes limited to its cut surface. Sliced cartilages retained their thickness, histology, and structural properties in the long term similar to intact cartilages whereas -contrary to expectations- crushed specimens had significantly higher thickness measurements at the end of 4 months.
    Conclusion: Sliced cartilage grafts prepared with an atraumatic cartilage slicer are an ideal camouflaging material with its uniform thickness, and malleability. Crushed cartilages seemingly getting thicker without histological findings could be explained by lower than actual initial measurements due to its structural weakness and getting squeezed when the standard pressure of the micrometer was applied.
    MeSH term(s) Animals ; Chondrocytes/transplantation ; Ear Cartilage/transplantation ; Graft Survival ; Humans ; Nasal Cartilages/surgery ; Nasal Septum ; Rabbits ; Rhinoplasty
    Language English
    Publishing date 2021-09-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-021-07079-8
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  5. Article ; Online: Analyzing Predictors of Bullying Victimization With Routine Activity and Social Bond Perspectives.

    Cecen-Celik, Hatice / Keith, Shelley

    Journal of interpersonal violence

    2016  Volume 34, Issue 18, Page(s) 3807–3832

    Abstract: Bullying victimization in school settings is a serious problem in many countries including the United States. It has been associated with serious incidents of school violence as well as detrimental physical, psychological, emotional, and social ... ...

    Abstract Bullying victimization in school settings is a serious problem in many countries including the United States. It has been associated with serious incidents of school violence as well as detrimental physical, psychological, emotional, and social consequences for its victims. Given its consequences, it is crucial to understand who is more likely to be targeted for bullying victimization. This study examines whether a number of important factors such as gender, physical and interactionist school security measures, and involvement in extracurricular activities influence an individual's risk of bullying victimization from social bond and routine activity perspectives. The study employs the 2011 School Crime Supplement of the National Crime Victimization Survey to investigate the causes of bullying victimization. The results show that gender, interactionist school security measures, and extracurricular activities affect an individual's likelihood of bullying victimization.
    MeSH term(s) Adolescent ; Bullying/psychology ; Bullying/statistics & numerical data ; Child ; Crime Victims/psychology ; Crime Victims/statistics & numerical data ; Female ; Humans ; Male ; Recreation ; Schools/organization & administration ; Students/psychology ; Students/statistics & numerical data ; United States ; Violence/statistics & numerical data
    Language English
    Publishing date 2016-10-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2028900-5
    ISSN 1552-6518 ; 0886-2605
    ISSN (online) 1552-6518
    ISSN 0886-2605
    DOI 10.1177/0886260516672941
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  6. Article ; Online: The Effect of Oral Montelukast Administration in Cholesteatoma Development and Inflammation: An Experimental Animal Model.

    Ocal, Ramazan / Kargin Kaytez, Selda / Yumusak, Nihat / Akkoca, Ozlem / Celik, Hatice / Arslan, Necmi

    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

    2021  Volume 42, Issue 5, Page(s) e568–e572

    Abstract: Hypothesis: We hypothesized that oral montelukast treatment could inhibit cholesteatoma formation in an experimental animal model.: Background: Inflammation and excessive proliferation have been described in the histopathology of cholesteatoma. The ... ...

    Abstract Hypothesis: We hypothesized that oral montelukast treatment could inhibit cholesteatoma formation in an experimental animal model.
    Background: Inflammation and excessive proliferation have been described in the histopathology of cholesteatoma. The aim of this study was to determine the effect of oral montelukast on cholesteatoma development.
    Methods: Eighteen healthy female Wistar albino rats weighing 250 g were chosen for the study. The animals were divided into two groups: group 1 received montelukast and group 2 was the control group. Intratympanic propylene glycol injection was administered into the left ears and physiologic serum was instilled into the right ears of the animals on the first, eighth, and fifteenth days. The effects of montelukast administration were evaluated by histological examination of the tympanic membrane and middle ear.
    Results: Group 1 (montelukast group) showed significant differences in terms of cholesteatoma formation, granulation, epithelial invagination, and inflammation. Cholesteatoma formation in the left ear was observed in 2 (22%) and 8 (89%) rats in groups 1 and 2, respectively (p = 0.015).
    Conclusion: Development of cholesteatoma and inflammation was significantly lower in the montelukast-administered group. Thus, oral montelukast was found effective in preventing cholesteatoma formation.
    MeSH term(s) Acetates ; Animals ; Cholesteatoma, Middle Ear ; Cyclopropanes ; Female ; Inflammation/drug therapy ; Models, Animal ; Quinolines ; Rats ; Rats, Wistar ; Sulfides
    Chemical Substances Acetates ; Cyclopropanes ; Quinolines ; Sulfides ; montelukast (MHM278SD3E)
    Language English
    Publishing date 2021-01-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2036790-9
    ISSN 1537-4505 ; 1531-7129
    ISSN (online) 1537-4505
    ISSN 1531-7129
    DOI 10.1097/MAO.0000000000003061
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    Zs.A 1554: Show issues Location:
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  7. Article ; Online: Epistaksisin Nadir Bir Nedeni: Nazofarengeal Huridiniasis.

    Çağlı, Ali / Çelik, Hatice

    Turkiye parazitolojii dergisi

    2015  Volume 39, Issue 2, Page(s) 171–173

    Abstract: The leech that is taken by ingestion of contaminated water can settle on any location at upper respiratory tract from nose to larynx. It sucks blood by adhering to the mucosa and causes mucosal bleeding by secreting hirudin. If the leech goes forward to ... ...

    Title translation An Uncommon Cause of Epistaxis: Nasopharyngeal Hirudiniasis.
    Abstract The leech that is taken by ingestion of contaminated water can settle on any location at upper respiratory tract from nose to larynx. It sucks blood by adhering to the mucosa and causes mucosal bleeding by secreting hirudin. If the leech goes forward to the larynx, this can be life threatening due to severe airway obstruction. We are presenting 23 year-old male patient who admitted to our hospital with anterior and posterior nose bleeding and dysphagia due to the leech located in the posterior wall of the nasopharynx. The treatment and differential diagnosis of epistaxis is discussed in this article.
    MeSH term(s) Animals ; Deglutition Disorders/parasitology ; Diagnosis, Differential ; Epistaxis/diagnosis ; Epistaxis/parasitology ; Humans ; Leeches/physiology ; Male ; Nasopharyngeal Diseases/complications ; Nasopharyngeal Diseases/parasitology ; Nasopharynx/parasitology ; Parasitic Diseases/complications ; Parasitic Diseases/parasitology ; Young Adult
    Language Turkish
    Publishing date 2015-06
    Publishing country Turkey
    Document type Case Reports ; English Abstract ; Journal Article
    ISSN 2146-3077
    ISSN (online) 2146-3077
    DOI 10.5152/tpd.2015.3614
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  8. Article ; Online: Effect of probiotics in experimental otitis media with effusion.

    Kaytez, Selda Kargin / Ocal, Ramazan / Yumusak, Nihat / Celik, Hatiçe / Arslan, Necmi / Ibas, Mustafa

    International journal of pediatric otorhinolaryngology

    2020  Volume 132, Page(s) 109922

    Abstract: Objectives: The article's aim was to investigate the effects of probiotics in the experimental otitis media with effusion.: Materials and methods: Twenty-four male Wistar albino rats were used. They were divided into four groups. Experimental otitis ... ...

    Abstract Objectives: The article's aim was to investigate the effects of probiotics in the experimental otitis media with effusion.
    Materials and methods: Twenty-four male Wistar albino rats were used. They were divided into four groups. Experimental otitis media with effusion was created by intratympanic histamine injection. The effusion was confirmed by otomicroscopic examination 24 h after injection. Group 1; did not receive any treatment, group 2; received probiotics for 7 days after the detection of effusion, group 3; received probiotics for 7 days prior to injection of histamine, group 4; received probiotics for 7 days before injection of histamine and 7 days after detection of effusion. After detection of effusion, animals were sacrificed. Otomicroscopic evaluation was done to determine the effusion. In histopathological examination neutrophil leukocyte counts were determined in 25 areas of the sub-mucosa of the temporal bulla.
    Results: The otomicroscopic ear effusions' healing rate in group 1 was 10%, in group 2 was 25%, in group 3 was 50%, and in group 4 was 100% (p < 0,013). The mean counts of submucosal neutrophil leukocyte from 25 areas of the temporal bulla of group 1 was 86,8 ± 24, group 2 was 66,5 ± 21, group 3 was 66,2 ± 16, and group 4 was 26,3 ± 6,5 (p < 0,001).
    Conclusion: Probiotics have a curative effect on the prevention and treatment of otitis media with effusion. This result may be related to their anti-inflammatory effects. Therefore, probiotics can be widely used in the age group at risk for otitis media with effusion as a complementary therapy by dietary supplements.
    Level of evidence: NA.
    MeSH term(s) Animals ; Disease Models, Animal ; Ear, Middle/immunology ; Histamine ; Male ; Neutrophils ; Otitis Media with Effusion/chemically induced ; Otitis Media with Effusion/immunology ; Otitis Media with Effusion/prevention & control ; Otitis Media with Effusion/therapy ; Probiotics/therapeutic use ; Rats ; Rats, Wistar
    Chemical Substances Histamine (820484N8I3)
    Language English
    Publishing date 2020-02-01
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2020.109922
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    Zs.A 1507: Show issues Location:
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    Zs.MO 134: Show issues

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  9. Article ; Online: Copper and levonorgestrel containing intrauterine devices: comparison of their effect on oxidative stress markers.

    Buyuk, Gul Nihal / Oskovi-Kaplan, Z Asli / Kansu-Celik, Hatice / Neselioglu, Salim / Erel, Ozcan / Engin-Ustun, Yaprak

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

    2021  Volume 37, Issue 4, Page(s) 320–323

    Abstract: Objective: We aimed to evaluate the oxidative stress by measuring the thiol-disulfide balance in women who use either T380A or LNG-IUD as a contraceptive method. ...

    Abstract Objective: We aimed to evaluate the oxidative stress by measuring the thiol-disulfide balance in women who use either T380A or LNG-IUD as a contraceptive method.
    MeSH term(s) Adult ; Contraceptive Agents, Hormonal/administration & dosage ; Disulfides/metabolism ; Female ; Humans ; Intrauterine Devices, Copper ; Intrauterine Devices, Medicated ; Levonorgestrel/administration & dosage ; Oxidative Stress ; Sulfhydryl Compounds/metabolism
    Chemical Substances Contraceptive Agents, Hormonal ; Disulfides ; Sulfhydryl Compounds ; Levonorgestrel (5W7SIA7YZW)
    Language English
    Publishing date 2021-02-17
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 639237-4
    ISSN 1473-0766 ; 0951-3590
    ISSN (online) 1473-0766
    ISSN 0951-3590
    DOI 10.1080/09513590.2021.1878132
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    Zs.MO 608: Show issues

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  10. Article ; Online: The Effect of Curcumin on the Prevention of Myringosclerosis in Rats.

    Akkoca, Özlem / Kargın Kaytez, Selda / Yumuşak, Nihat / Bilgen, Akif Sinan / Kavuzlu, Ali / Öcal, Ramazan / Çelik, Hatice / Arslan, Necmi

    Turkish archives of otorhinolaryngology

    2021  Volume 59, Issue 1, Page(s) 26–32

    Abstract: Objective: The aim of this study was to investigate the preventative effect of oral curcumin (CMN) on myringosclerosis (MS) in an experimental rat model.: Methods: The study included 21 female Wistar albino rats randomly separated into three groups. ... ...

    Abstract Objective: The aim of this study was to investigate the preventative effect of oral curcumin (CMN) on myringosclerosis (MS) in an experimental rat model.
    Methods: The study included 21 female Wistar albino rats randomly separated into three groups. Group 1 was given no treatment (control group). In Group 2 and Group 3, the tympanic membrane (TM) was perforated using a sterile ear pick. The rats in Group 3 were administered oral CMN 200 mg/kg/day. All rats were sacrificed after 16 days. Otomicroscopic and histopathologic examinations were performed on the tympanic membranes.
    Results: Histopathologic examinations revealed that there were statistically significant differences between Group 2 and Group 3 in terms of MS degrees (p<0.001) and mean thicknesses of TMs (p<0.001), but there were no differences between Group 1 and Group 3. In respect of MS detected by otomicroscopy, a statistically significant difference was determined between Groups 1 and 2 (p<0.001) and between Groups 2 and 3 (p<0.01), but there was no significant difference between Group 1 and Group 3 (p=0.575).
    Conclusion: Orally administered CMN can prevent myringosclerosis formation in experimentally induced myringotomies.
    Language English
    Publishing date 2021-03-26
    Publishing country Turkey
    Document type Journal Article
    ISSN 2667-7474
    ISSN (online) 2667-7474
    DOI 10.4274/tao.2020.5827
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