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  1. Article ; Online: Response to `Rehospitalization indications of children hospitalized for COVID-19 infections and long COVID`.

    Cem, Ela / Özenen, Gizem Güner / Bayram, Nuri / Devrim, İlker

    The Turkish journal of pediatrics

    2024  Volume 66, Issue 1, Page(s) 145–146

    MeSH term(s) Child ; Humans ; Patient Readmission ; Post-Acute COVID-19 Syndrome ; COVID-19 ; Hospitalization ; Risk Factors
    Language English
    Publishing date 2024-03-25
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 123487-0
    ISSN 2791-6421 ; 0041-4301
    ISSN (online) 2791-6421
    ISSN 0041-4301
    DOI 10.24953/turkjped.2023.800
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  2. Article ; Online: BD Chloraprep™ ("2 % chlorhexidine with 70 % isopropyl alcohol") versus povidone iodine plus alcohol, for prevention of blood culture contamination at children: An investigator-initiated, open-label, single centre, randomized controlled trial.

    Devrim, İlker / Şahinkaya, Şahika / Yılmaz Çelebi, Miray / Kaçar, Pelin / Cem, Ela / Sözen, Ceren / Yaman, Yakup / Ayhan, Fahri Yüce / Bayram, Süleyman Nuri

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

    2023  Volume 30, Issue 6, Page(s) 494–498

    Abstract: Introduction: One of the important problems that lower the diagnostic value of blood culture is contamination with skin organisms. The povidone-iodine, alcohol, and chlorhexidine gluconate alcohol are used for disinfection prior to blood sampling for ... ...

    Abstract Introduction: One of the important problems that lower the diagnostic value of blood culture is contamination with skin organisms. The povidone-iodine, alcohol, and chlorhexidine gluconate alcohol are used for disinfection prior to blood sampling for culture.
    Methods: The investigator-initiated, open label, single centre, randomised trial compared blood culture contamination rates between two groups of patients in which using a povidone iodine skin-preparation process with the contamination rate for using "2 % chlorhexidine with 70 % isopropyl alcohol" skin-disinfection. The patients who required sampling for blood cultures were included in the study and study period was from 15 March 2023 to 15 July 2023.
    Results: A total of 400 blood cultures were obtained during the study, including 133 in the study group and 267 in the control group. In the total blood cultures, 11.75 % (n = 47) had microorganism isolation. Among them 39 (9.75 %) were contaminants and 8 (2 %) of them were true pathogens. The contaminant microorganisms were as following; 34 coagulase-negative Staphylococci, 3 Micrococcus spp, and 2 Streptococci viridans. The blood culture contamination rate in the study group was 5.3 % (n = 7) and 12.0 % (n = 32) in the control group, and significantly lower in the study group (p = 0.033). There is no significant difference regarding skin related side effects between two groups.
    Conclusions: This study, showed that 2 % chlorhexidine gluconate in 70 % isopropyl alcohol is more efficacious in children than 10 % povidone-iodine preparations for disinfecting the skin prior to blood specimen collection for prevention of blood culture contamination.
    MeSH term(s) Child ; Humans ; Povidone-Iodine/therapeutic use ; Chlorhexidine/therapeutic use ; Chlorhexidine/analogs & derivatives ; Anti-Infective Agents, Local/pharmacology ; Anti-Infective Agents, Local/therapeutic use ; 2-Propanol ; Blood Culture ; Ethanol/therapeutic use ; Skin
    Chemical Substances Povidone-Iodine (85H0HZU99M) ; chlorhexidine gluconate (MOR84MUD8E) ; Chlorhexidine (R4KO0DY52L) ; Anti-Infective Agents, Local ; 2-Propanol (ND2M416302) ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-12-12
    Publishing country Netherlands
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1355399-9
    ISSN 1437-7780 ; 1341-321X
    ISSN (online) 1437-7780
    ISSN 1341-321X
    DOI 10.1016/j.jiac.2023.12.001
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  3. Article ; Online: Successful treatment of life-threatening severe metabolic acidosis by continuous veno-venous hemodialysis in a child with diabetic ketoacidosis.

    Yesilbas, Osman / Cem, Ela / Cimbek, Emine Ayca

    Journal of pediatric endocrinology & metabolism : JPEM

    2018  Volume 31, Issue 9, Page(s) 1043–1045

    MeSH term(s) Adolescent ; Diabetic Ketoacidosis/therapy ; Female ; Hemofiltration/methods ; Humans ; Prognosis ; Remission Induction ; Time Factors
    Language English
    Publishing date 2018-08-18
    Publishing country Germany
    Document type Case Reports ; Letter
    ZDB-ID 1231070-0
    ISSN 2191-0251 ; 0334-018X
    ISSN (online) 2191-0251
    ISSN 0334-018X
    DOI 10.1515/jpem-2018-0232
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  4. Article ; Online: Comparative Analysis of Pediatric Brucellosis Cases With and Without Bacteremia.

    Yılmaz Çelebi, Miray / Böncüoğlu, Elif / Kıymet, Elif / Şahinkaya, Şahika / Cem, Ela / Gülderen, Mustafa / Kaçar, Pelin / Özdağ, Eda / Akaslan Kara, Aybüke / Güner Özenen, Gizem / Sorguç, Yelda / Ayhan, Fahri Yüce / Apa, Hurşit / Bayram, Süleyman Nuri / Devrim, İlker

    Vector borne and zoonotic diseases (Larchmont, N.Y.)

    2024  

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2047199-3
    ISSN 1557-7759 ; 1530-3667
    ISSN (online) 1557-7759
    ISSN 1530-3667
    DOI 10.1089/vbz.2023.0080
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  5. Article: Successful single-pass albumin dialysis in the management of severe calcium channel blocker poisoning.

    Yeşilbaş, Osman / Ramoğlu, Mehmet Gökhan / Çayan, Özlem Kahraman / Cem, Ela / Seven, Pınar

    Turk pediatri arsivi

    2020  Volume 55, Issue 1, Page(s) 82–84

    Language English
    Publishing date 2020-03-09
    Publishing country Turkey
    Document type Journal Article
    ISSN 1306-0015
    ISSN 1306-0015
    DOI 10.14744/TurkPediatriArs.2019.27880
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  6. Article: The evaluation of Candida-related central line-related bloodstream infections in pediatric cancer patients: A pre- and post-intervention study.

    Devrim, İlker / Celebi, Miray Yılmaz / Karakaya, Nurgul / Sahinkaya, Sahika / Acar, Sultan Okur / Cem, Ela / Demirağ, Bengü / Oruc, Yeliz / Kara, Aybuke Akaslan / Oymak, Yesim / Karapınar, Tuba Hilkay / Bayram, Nuri

    Journal of infection prevention

    2023  Volume 24, Issue 5, Page(s) 219–222

    Abstract: Aim/objections: The purpose of this study was to assess the efficacy of a central line maintenance bundle in preventing catheter-related (implanted venous access devices, port) Candida bloodstream infections.: Methods: The study encompassed two ... ...

    Abstract Aim/objections: The purpose of this study was to assess the efficacy of a central line maintenance bundle in preventing catheter-related (implanted venous access devices, port) Candida bloodstream infections.
    Methods: The study encompassed two distinct time periods, namely, pre-bundle and bundle. The number of catheter-related bloodstream infections (CRBSI) episodes per catheter days for each timeframe was determined.
    Findings/results: Upon implementation of the central line bundle, the rate of CRBSI reduced significantly from 4.27 per 1000 central line days in the pre-bundle period to 1.0 per 1000 central line days in the bundle period (
    Discussion: Using a central line bundle to avoid CRBSIs in pediatric cancer patients with ports led to a significant decrease in Candida species-related CRBSIs.
    Language English
    Publishing date 2023-08-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2595000-9
    ISSN 1757-1782 ; 1757-1774
    ISSN (online) 1757-1782
    ISSN 1757-1774
    DOI 10.1177/17571774231191334
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  7. Article ; Online: Rehospitalization indications of children hospitalized for COVID-19 infections after discharge: Should we suspect long COVID?

    Cem, Ela / Kıymet, Elif / Böncüoğlu, Elif / Şahinkaya, Şahika / Çelebi, Miray Yılmaz / Gülderen, Mustafa / Kara, Aybüke Akaslan / Özenen, Gizem Güner / Bayram, Nuri / Devrim, İlker

    The Turkish journal of pediatrics

    2023  Volume 65, Issue 4, Page(s) 583–591

    Abstract: Background: Complications that may develop in children after coronavirus disease 2019 (COVID-19) infections are unknown. The `Long COVID` syndrome is a new process that can also be identified in children. Therefore, in this study, the conditions that ... ...

    Abstract Background: Complications that may develop in children after coronavirus disease 2019 (COVID-19) infections are unknown. The `Long COVID` syndrome is a new process that can also be identified in children. Therefore, in this study, the conditions that may develop in children after COVID-19 infection were discussed, and the indications for rehospitalizations were reviewed.
    Methods: This retrospective cohort study was conducted in a tertiary children`s hospital in İzmir, Türkiye. All children who were rehospitalized in the study center after discharge, and the indications for readmissions were screened.
    Results: Since the beginning of the pandemic, 777 children with COVID-19 infection were hospitalized, including 98 (12.6%) cases rehospitalized for any indication. Fifty-five (56.1%) patients were male, and 43 (43.9%) were female. The mean age of the study population was 79.3±63.5 months (1 month to 17 years). Among these 98 patients, 76 (77.6%) were rehospitalized because of the presence of their primary underlying disease, nonspecific infectious diseases unrelated to COVID-19, and the need to perform certain surgical procedures. The remaining 22 (22.4%) patients presented with symptoms such as fatigue, fever, abdominal pain, and myalgia after the COVID-19 infection. No other underlying cause was detected in approximately one-third of the patients, whose manifestations were found to be consistent with long COVID syndrome.
    Conclusions: The findings of acute COVID-19 infection are well characterized, but there is still limited data on its long-term outcomes. The majority of the study population that had no underlying disease were thought to have complications from the COVID-19 infection. Therefore, although the incidence rate of long COVID syndrome in childhood has not been revealed so far, it should be kept in mind among relevant differential diagnoses.
    MeSH term(s) Humans ; Child ; Female ; Male ; Post-Acute COVID-19 Syndrome ; COVID-19/complications ; Patient Readmission ; Patient Discharge ; Retrospective Studies
    Language English
    Publishing date 2023-09-04
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 123487-0
    ISSN 2791-6421 ; 0041-4301
    ISSN (online) 2791-6421
    ISSN 0041-4301
    DOI 10.24953/turkjped.2022.829
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  8. Article ; Online: A hidden burden of disease in a specific group: Evaluation of COVID-19 seroconversion rates in pediatric patients with leukemia.

    Yılmaz Çelebi, Miray / Şahinkaya, Şahika / Cem, Ela / Akaslan Kara, Aybüke / Özdağ, Eda / Ayhan, Fahri Y / Karakaya, Nurgül / Odaman Al, Işık / Gözmen, Salih / Hilkay Karapınar, Tuba / Oymak, Yeşim / Bayram, Süleyman N / Devrim, İlker

    American journal of infection control

    2023  Volume 52, Issue 3, Page(s) 320–323

    Abstract: Background: SARS-CoV-2, a respiratory viral disease, is thought to have a more severe course in patients with malignancy and low immune systems.: Methods: This prospective single-center study was conducted at the University of Health Sciences Dr ... ...

    Abstract Background: SARS-CoV-2, a respiratory viral disease, is thought to have a more severe course in patients with malignancy and low immune systems.
    Methods: This prospective single-center study was conducted at the University of Health Sciences Dr Behçet Uz Children's Hospital from September 22 to December 31, 2021. Asymptomatic COVID-19 transmission rates were assessed using SARS-CoV-2 serology in patients with leukemia who had no history of COVID-19 infection.
    Results: Among the 54 patients, 19 (35.2%) were females and 35 (64.8%) were males. The median age was 5.5 years (min 6 months, max 17 years). Forty-nine (90.5%) of the leukemia patients had acute lymphoblastic leukemia, while 5 (9.5%) had acute myeloid leukemia. Five of the 54 patients had a history of COVID-19 or contact with a positive person. SARS-CoV-2 IgG positivity was detected in 18 (36.7%) of 49 patients with no history of COVID-19 infection.
    Discussion: Leukemia patients have a high seroconversion for SARS-CoV-2 without showing any symptoms supporting the asymptomatic course of COVID-19 infection in this risk group.
    Conclusion: As a result, patients with leukemia may have a high rate of COVID-19 seroconversion without showing symptoms.
    MeSH term(s) Male ; Female ; Humans ; Child ; Child, Preschool ; COVID-19 ; SARS-CoV-2 ; Seroconversion ; Prospective Studies ; Antibodies, Viral ; Leukemia/complications ; Cost of Illness
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2023-09-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2023.09.006
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  9. Article ; Online: Do not Miss the Diagnosis of Bacterial Sepsis in Infants With COVID-19.

    Böncüoğlu, Elif / Kiymet, Elif / Yilmaz Çelebi, Miray / Cem, Ela / Gülderen, Mustafa / Şahinkaya, Şahika / Bayram, Nuri / Devrim, İlker

    The Pediatric infectious disease journal

    2021  Volume 41, Issue 1, Page(s) e31–e32

    MeSH term(s) Bacterial Infections ; COVID-19 ; Humans ; Infant ; SARS-CoV-2 ; Sepsis/diagnosis
    Language English
    Publishing date 2021-11-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003351
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  10. Article ; Online: Can Hematological Findings of COVID-19 in Pediatric Patients Guide Physicians Regarding Clinical Severity?

    Ötiken Arıkan, Kamile / Şahinkaya, Şahika / Böncüoğlu, Elif / Kıymet, Elif / Cem, Ela / Akaslan Kara, Aybüke / Bayram, Nuri / Devrim, İlker

    Turkish journal of haematology : official journal of Turkish Society of Haematology

    2021  Volume 38, Issue 3, Page(s) 243–245

    MeSH term(s) Adolescent ; Blood Cell Count ; COVID-19/complications ; COVID-19/pathology ; COVID-19/virology ; Child ; Child, Preschool ; Female ; Hematologic Tests ; Hemoglobins/analysis ; Humans ; Male ; Neutropenia/diagnosis ; Neutropenia/etiology ; Pediatricians/psychology ; Retrospective Studies ; SARS-CoV-2/isolation & purification ; Severity of Illness Index
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2021-04-28
    Publishing country Turkey
    Document type Letter
    ZDB-ID 2185903-6
    ISSN 1308-5263 ; 1300-7777
    ISSN (online) 1308-5263
    ISSN 1300-7777
    DOI 10.4274/tjh.galenos.2021.2021.0157
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