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  1. Article ; Online: Real-time ultrasound evaluation of CORE muscle activity in a simultaneous contraction in subjects with non-specific low back pain and without low-back pain. Protocol of an observational case-control study.

    Cervera-Cano, María / Sáez-García, María Carmen / Valcárcel-Linares, David / Fernández-Carnero, Samuel / López-González, Luis / Gallego-Izquierdo, Tomás / Pecos-Martin, Daniel

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0285441

    Abstract: Non-specific low back pain represents 90-95% of all cases of low back pain and it has a prevalence of 18% in the adult population, assuming a great socioeconomic impact. The main objective of this observational case-control study study is to evaluate if ... ...

    Abstract Non-specific low back pain represents 90-95% of all cases of low back pain and it has a prevalence of 18% in the adult population, assuming a great socioeconomic impact. The main objective of this observational case-control study study is to evaluate if there are differences in the simultaneous contraction of the core muscles between nonspecific low back pain and healthy subjects. This study will be carried out in the Physiotherapy department of the University of Alcalá. Eighty-two participants <18 years old, will be recruited, paired with NSLBP (n = 41) and healthy (n = 41). The main outcome will be the onset muscle contraction of lateral abdominal wall (internal oblique, external oblique and transversus abdominis), pelvic floor, lumbar multifidus and respiratory diafragm. The maneuvers that the subjects will perform will be abdominal drawing in maneouver, contralateral arm lift, valsalva, and voluntary pelvic floor contraction in sitting and standing. As a secondary objective, to analyze the amount of contraction of each muscle group and the capacity of the diaphragms to be excreted in both groups of subjects. Finally, to relate pain and disability.
    MeSH term(s) Adult ; Humans ; Adolescent ; Low Back Pain/diagnostic imaging ; Case-Control Studies ; Abdominal Muscles/diagnostic imaging ; Abdominal Muscles/physiology ; Pelvic Floor ; Muscle Contraction/physiology ; Abdominal Wall ; Observational Studies as Topic
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0285441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tratamiento farmacológico en tiempos de incertidumbre: uso de la hidroxicloroquina/cloroquina en el tratamiento de COVID-19.

    Mayayo-Vicente, S / Rodriguez Salvanés, F / Gallego-Arenas, A / Sánchez-Gómez, L M / Ruiz-López, M / Sierra García, B / Jurado-López, A / Arriola-Bolado, P / Cervera Cano, M / Novella-Arribas, B

    Semergen

    2020  Volume 46 Suppl 1, Page(s) 20–27

    Abstract: Background and objectives: In this moments, of extreme gravity in which we find ourselves, and in the uncertainty face about the most effective treatment against COVID-19 disease and with the aim of find the evidence that support the chloroquine/ ... ...

    Title translation Pharmacological treatment in uncertainty times: Hydroxychloroquine/chloroquine use in the COVID-19 treatment.
    Abstract Background and objectives: In this moments, of extreme gravity in which we find ourselves, and in the uncertainty face about the most effective treatment against COVID-19 disease and with the aim of find the evidence that support the chloroquine/hydroxychloroquine use recommendation to treat COVID-19 disease, a systematic review of published studies and RCT studies publishes until April 28, 2020 was carried out.
    Material and methods: A systematic search was carried out in PubMed with the keywords COVID-19 and their synonyms and hydroxychloroquine/chloroquine. The data selection and extraction was elaborated by two researchers, independently. The results were discussed with a Primary Care physicians clinical group and the results were synthesized using GRADE methodology.
    Results: A good quality systematic review was found that includes articles with a high risk of bias. And 8 EC launched that will produce results beyond May 2020.
    Conclusions: Although the conclusions of the systematic review generate a low confidence in the results, and the clinical variables that show benefit are intermediate variables, the side effects are acceptable and could be minimized with the use of QT lengthening risk tools, so it is could make a weak recommendation in favor of the use of chloroquine/hydroxychloroquine in patients with mild-moderate stage COVID-19.
    MeSH term(s) COVID-19/drug therapy ; Chloroquine/therapeutic use ; Coronavirus Infections/drug therapy ; Humans ; Hydroxychloroquine/therapeutic use ; Uncertainty
    Chemical Substances Hydroxychloroquine (4QWG6N8QKH) ; Chloroquine (886U3H6UFF)
    Keywords covid19
    Language Spanish
    Publishing date 2020-07-11
    Publishing country Spain
    Document type Journal Article ; Systematic Review
    ISSN 1578-8865
    ISSN (online) 1578-8865
    DOI 10.1016/j.semerg.2020.06.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Core Synergies Measured with Ultrasound in Subjects with Chronic Non-Specific Low Back Pain and Healthy Subjects: A Systematic Review.

    Cervera-Cano, Maria / López-González, Luis / Valcárcel-Linares, David / Fernández-Carnero, Samuel / Achalandabaso-Ochoa, Alexander / Andrés-Sanz, Verónica / Pecos-Martín, Daniel

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 22

    Abstract: Low back pain represents the leading cause of disability since 1990. In 90% of cases, it is classified as non-specific low back pain, being chronic in 10% of subjects. Ultrasound has proven to be an effective measurement tool to observe changes in the ... ...

    Abstract Low back pain represents the leading cause of disability since 1990. In 90% of cases, it is classified as non-specific low back pain, being chronic in 10% of subjects. Ultrasound has proven to be an effective measurement tool to observe changes in the activity and morphology of the abdominal muscles. This article reviews which core synergies are studied with ultrasound in healthy subjects and with chronic non-specific low back pain. A systematic review was conducted on studies analyzing synergies between two or more core muscles. Publications from 2005 until July 2021 were identified by performing structured searched in Pubmed/MEDLINE, PEDro and WOS. Fifteen studies were eligible for the final systematic review. A total of 56% of the studies established synergies between the core muscles and 44% between the homo and contralateral sides of the core muscles. The most studied core synergies were transversus abdominis, internal oblique and external oblique followed by the rectus abdominis and the lumbar multifidus. No studies establishing synergies with diaphragm and pelvic floor were found. Eight studies were conducted in healthy subjects, five studies in subjects with chronic non-specific low back pain compared to healthy subjects and two studies in subjects with chronic non-specific low back pain.
    MeSH term(s) Humans ; Low Back Pain/diagnostic imaging ; Healthy Volunteers ; Abdominal Muscles/diagnostic imaging ; Abdominal Muscles/anatomy & histology ; Abdominal Muscles/physiology ; Ultrasonography ; Thorax
    Language English
    Publishing date 2022-11-10
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22228684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Abdominal and Pelvic Floor Activity Related to Respiratory Diaphragmatic Activity in Subjects with and without Non-Specific Low Back Pain.

    Sicilia-Gomez, Cristina / Fernández-Carnero, Samuel / Martin-Perez, Alicia / Cuenca-Zaldívar, Nicolas / Naranjo-Cinto, Fermin / Pecos-Martín, Daniel / Cervera-Cano, Maria / Nunez-Nagy, Susana

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 10

    Abstract: One of the advances in physiotherapy in recent years is the exploration and treatment by ultrasound imaging. This technique makes it possible to study the relationship between the musculature of the anterolateral wall of the abdomino-pelvic cavity, the ... ...

    Abstract One of the advances in physiotherapy in recent years is the exploration and treatment by ultrasound imaging. This technique makes it possible to study the relationship between the musculature of the anterolateral wall of the abdomino-pelvic cavity, the pelvic floor muscles and the diaphragm muscle, among others, and thus understand their implication in non-specific low back pain (LBP) in pathological subjects regarding healthy subjects.
    Objective: To evaluate by RUSI (rehabilitative ultrasound imaging) the muscular thickness at rest of the abdominal wall, the excursion of the pelvic floor and the respiratory diaphragm, as well as to study their activity.
    Methodology: Two groups of 46 subjects each were established. The variables studied were: non-specific low back pain, thickness and excursion after tidal and forced breathing, pelvic floor (PF) excursion in a contraction and thickness of the external oblique (EO), internal oblique (IO) and transverse (TA) at rest.
    Design: Cross-sectional observational study.
    Results: Good-to-excellent reliability for measurements of diaphragm thickness at both tidal volume (TV) (inspiration: 0.763, expiration: 0.788) and expiration at forced volume (FV) (0.763), and good reliability for inspiration at FV (0.631). A correlation was found between the EO muscle and PF musculature with respect to diaphragmatic thickness at TV, inspiration and expiration, and inspiration at FV, in addition to finding significant differences in all these variables in subjects with LBP.
    Conclusion: Subjects with LBP have less thickness at rest in the OE muscle, less excursion of the pelvic diaphragm, less diaphragmatic thickness at TV, in inspiration and expiration, and in inspiration to FV.
    Language English
    Publishing date 2022-10-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12102530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Tratamiento farmacológico en tiempos de incertidumbre: uso de la hidroxicloroquina/cloroquina en el tratamiento de COVID-19./ [Pharmacological treatment in uncertainty times: Hydroxychloroquine/chloroquine use in the COVID-19 treatment]

    Mayayo-Vicente, S / Rodriguez Salvanés, F / Gallego-Arenas, A / Sánchez-Gómez, L M / Ruiz-López, M / Sierra García, B / Jurado-López, A / Arriola-Bolado, P / Cervera Cano, M / Novella-Arribas, B

    Semergen

    Abstract: BACKGROUND AND OBJECTIVES: In this moments, of extreme gravity in which we find ourselves, and in the uncertainty face about the most effective treatment against COVID-19 disease and with the aim of find the evidence that support the chloroquine/ ... ...

    Abstract BACKGROUND AND OBJECTIVES: In this moments, of extreme gravity in which we find ourselves, and in the uncertainty face about the most effective treatment against COVID-19 disease and with the aim of find the evidence that support the chloroquine/hydroxychloroquine use recommendation to treat COVID-19 disease, a systematic review of published studies and RCT studies publishes until April 28, 2020 was carried out. MATERIAL AND METHODS: A systematic search was carried out in PubMed with the keywords COVID-19 and their synonyms and hydroxychloroquine/chloroquine. The data selection and extraction was elaborated by two researchers, independently. The results were discussed with a Primary Care physicians clinical group and the results were synthesized using GRADE methodology. RESULTS: A good quality systematic review was found that includes articles with a high risk of bias. And 8 EC launched that will produce results beyond May 2020. CONCLUSIONS: Although the conclusions of the systematic review generate a low confidence in the results, and the clinical variables that show benefit are intermediate variables, the side effects are acceptable and could be minimized with the use of QT lengthening risk tools, so it is could make a weak recommendation in favor of the use of chloroquine/hydroxychloroquine in patients with mild-moderate stage COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #640474
    Database COVID19

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  6. Article ; Online: Tratamiento farmacológico en tiempos de incertidumbre

    Mayayo-Vicente, S. / Rodriguez Salvanés, F. / Gallego-Arenas, A. / Sánchez-Gómez, L.M. / Ruiz-López, M. / Sierra García, B. / Jurado-López, A. / Arriola-Bolado, P. / Cervera Cano, M. / Novella-Arribas, B.

    Medicina de Familia. SEMERGEN

    uso de la hidroxicloroquina/cloroquina en el tratamiento de COVID-19

    2020  Volume 46, Page(s) 20–27

    Keywords Family Practice ; Public Health, Environmental and Occupational Health ; covid19
    Language Spanish
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 1138-3593
    DOI 10.1016/j.semerg.2020.06.016
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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