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Article ; Online: In-flight medical emergencies during commercial travel.

Ceyhan, Mehmet Ali / Menekşe, İbrahim Ethem

2021 Volume 28, Issue 7

Abstract: Background: Growing number of passengers travelling by air is associated with increased in-flight emergency medical events (IEMEs). However, there are scarce data regarding IEMEs during commercial travels. In this study, analysis of IEMEs occurring ... ...

Abstract	Background: Growing number of passengers travelling by air is associated with increased in-flight emergency medical events (IEMEs). However, there are scarce data regarding IEMEs during commercial travels. In this study, analysis of IEMEs occurring among adult and paediatric passengers during commercial international and domestic flights of a major airline company was targeted. Methods: Data regarding IEMEs recorded in all international and domestic flights of a major airline company between 1 January 2018 and 31 December 2020 were collected. Demographics, adult and paediatric IEMEs, in-flight deaths and aircraft diversions (ADs) were analysed. Results: Total number of passengers was 177 400 748 and a number of 22 541 (0.012%) IEMEs occurred. The frequency of IEMEs per 1 million passengers was 127. The number of male patients suffering from IEMEs was 8387 (37.2%), while the number female patients was 10 853 (48.1%). Median age of adult and paediatric patients were 43, [32-57], 4, [2-10], respectively. The most common cause of IEMEs in adult patients was headache (3424 IEMEs, 15.1%) and it was fever in paediatric patients (688 IEMEs, 3.05%). Multiple symptoms were present in 8449 IEMEs (37.4%). On-board doctors managed events in more than half of IEMEs (13 295 IEMEs, 58.9%). AD was required in 255 (1.13%) IEMEs. The most common reason for AD was chest pain (45 IEMEs, 17.6%) in adult patients. The most common reason for AD in paediatric patients was epileptic seizures (nine IEMEs, 3.5%). A total of 46 (0.2%) patients, including 2 (0.008%) paediatric patients, died. Conclusions: Majority of IEMEs are not life-threatening conditions, which can be easily managed by cabin crew or on-board doctors without AD. Multiple symptoms can be present in a patient suffering from IEME. Ground-to-air medical assistance may help optimization of diagnosis and decision for AD.
MeSH term(s)	Adult ; Aerospace Medicine ; Aircraft ; Child ; Emergencies ; Female ; Headache/epidemiology ; Headache/etiology ; Humans ; Male ; Travel
Language	English
Publishing date	2021-06-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1212504-0
ISSN	1708-8305 ; 1195-1982
ISSN (online)	1708-8305
ISSN	1195-1982
DOI	10.1093/jtm/taab094
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Article ; Online: Health Care Services in Shopping Centers: A Routine Mass-Gathering Event.

Ceyhan, Mehmet Ali / Demir, Gültekin Günhan

Prehospital and disaster medicine

2020 Volume 35, Issue 6, Page(s) 669–675

Abstract: Background: Shopping centers (SCs) are social areas with a group of commercial establishments which attract customers of numerous people every day. However, analysis of urgent health conditions and provided health care in SCs has not been performed so ... ...

Abstract	Background: Shopping centers (SCs) are social areas with a group of commercial establishments which attract customers of numerous people every day. However, analysis of urgent health conditions and provided health care in SCs has not been performed so far. Objective: The aim of the study was to perform a comparative analysis of clients visiting SCs and demographics, complaints, and health care of patients admitted to Emergency Medical Intervention Units (EMIU) located in grand SCs in Ankara, Turkey. Methods: Customer and health care records of nine grand SCs in Ankara from January 1, 2018 through December 31, 2018 were evaluated retrospectively. Health care services in EMIUs of SCs were provided by employed medical staff. Data including demographic characteristics, complaints, treatment protocols, discharge, and referral to hospital of the patients were retrospectively analyzed from medical registration forms. Results: Medical records of nine grand SCs were analyzed. Number of customers could not be obtained in three SCs due to privacy issues and were not included in patient presentation rate (PPR) and transport-to-hospital rate (TTHR) calculation. Total number of customers in the remaining six SCs were 53,277,239. The total number of patients seeking medical care was 6,749. The number of patients seeking health care in six SCs with known number of customers was 4,498 and PPR ranged from 0.018 to 0.381 patients per 1,000 attendants. The median age of the recorded 4,065 patients (60.2%) was 28 (interquartile range [IQR]: 38-21), and 3,611 (53.5%) of the patients admitted to EMIUs were female. The number of patients treated in the SC was 4,634 (68.6%) and 189 patients (2.8%) were transferred-to-hospital by ambulance for further evaluation and treatment. Transportation to hospital was required in 125 patients who sought medical care in six SCs which provided total number of customers, and TTHR ranged from 0.000 to 0.005 patients per 1,000 attendants. No sudden cardiac death was seen. Medical conditions were the primary reasons for seeking health care. The most frequent causes of presentation were laceration and abrasions (639 patients, 9.4%). Conclusion: The PPR and TTHR in SCs are low. The most common causes of presentation are minor conditions and injuries. Majority of urgent medical conditions in SCs can be managed by health care providers in EMIUs.
MeSH term(s)	Adult ; Commerce ; Crowding ; Emergencies/epidemiology ; Emergency Service, Hospital ; Female ; Humans ; Male ; Patient Acceptance of Health Care ; Turkey/epidemiology ; Young Adult
Language	English
Publishing date	2020-10-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1025975-2
ISSN	1945-1938 ; 1049-023X
ISSN (online)	1945-1938
ISSN	1049-023X
DOI	10.1017/S1049023X2000120X
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Zs.A 2859: Show issues

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Article ; Online: Impact of COVID-19 Lockdown on Traumatic Bone Fracture Patterns and Hospital Outcomes in 1646 Elderly Patients: A Retrospective Study in Turkey.

Durak, Ahmet Akif / Ergin, Mehmet / Gürü, Selahattin / Oğuztürk, Hakan / Celik, Gulhan Kurtoglu / Gökhan, Servan / Ceyhan, Mehmet Ali

Medical science monitor : international medical journal of experimental and clinical research

2024 Volume 30, Page(s) e942916

Abstract: BACKGROUND During the Coronavirus Disease-2019 (COVID-19) pandemic-related lockdowns, modifications in trauma-related behavior and other factors in the elderly population may have occurred. The present retrospective study aimed to compare outcomes from ... ...

Abstract	BACKGROUND During the Coronavirus Disease-2019 (COVID-19) pandemic-related lockdowns, modifications in trauma-related behavior and other factors in the elderly population may have occurred. The present retrospective study aimed to compare outcomes from emergency admissions to a major trauma center in Turkey of 1646 elderly patients with traumatic bone fractures that occurred before, during, and after the COVID-19 pandemic lockdown period. MATERIAL AND METHODS A cohort of 1646 elderly trauma patients admitted between September 15, 2019 and September 15, 2020 were retrospectively scanned from the hospital registry system and were grouped as admitted during the COVID-19 pandemic before (Group 1), during (Group 2), or after (Group 3) the lockdown restrictions. Demographic and clinical data were examined by making comparisons between the 3 groups. RESULTS In all groups, female sex was more prevalent. Fractures were more common in the ulna and femur than in other bones (P=0.026, P=0.035). Among the groups, in Group 2, injuries due to the mechanism of falling from one's own height on the ground were more prominent (79.2%). Hospital costs were lower in Group 1 (P<0.001). The majority of hospitalized patients (n=874; 53.1%) were in Group 2 (P=0.009). CONCLUSIONS During pandemic lockdowns, the mechanism of falling from one's own height was more common in the elderly population. The ulna and femur were the predominant bones fractured. Therefore, during lockdown periods, precautions should be taken to prevent the elderly from falling from their own height.
MeSH term(s)	Humans ; Aged ; Female ; Retrospective Studies ; Turkey ; Pandemics ; COVID-19 ; Communicable Disease Control ; Fractures, Bone ; Hospitals
Language	English
Publishing date	2024-01-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	1439041-3
ISSN	1643-3750 ; 1234-1010
ISSN (online)	1643-3750
ISSN	1234-1010
DOI	10.12659/MSM.942916
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Zs.A 4924: Show issues

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Article ; Online: Characterization of invasive Neisseria meningitidis isolates recovered from children in Turkey during a period of increased serogroup B disease, 2013-2017.

Ceyhan, Mehmet / Ozsurekci, Yasemin / Lucidarme, Jay / Borrow, Ray

Vaccine

2020 Volume 38, Issue 19, Page(s) 3545–3552

Abstract: Diverse Neisseria meningitidis strains belonging to various serogroups and clonal complexes cause epidemic and endemic life-threatening disease worldwide. This study aimed to investigate the genetic diversity of recent invasive meningococci in Turkey ... ...

Abstract	Diverse Neisseria meningitidis strains belonging to various serogroups and clonal complexes cause epidemic and endemic life-threatening disease worldwide. This study aimed to investigate the genetic diversity of recent invasive meningococci in Turkey with respect to multilocus sequence type (MLST) and also meningococcal serogroup B (MenB) vaccine antigens to enable assessment of potential MenB strain coverage using the genetic Meningococcal Antigen Typing System (gMATS). Fifty-four isolates, representing 37.5% of all pediatric (ages 0-18 years) invasive meningococcal disease cases in Turkey from January 2013 to December 2017, underwent genome sequence analysis. Thirty-six (66.7%) isolates were MenB, 10 (18.5%) were serogroup W (MenW), 4 (7.4%) were serogroup A (MenA), 3 (5.6%) were serogroup Y (MenY) and 1 (1.8%) was serogroup X (MenX). The MenB isolates were diverse with cc35 (19.4%), cc41/44 (19.4%) and cc32 (13.8%) as the most prevalent clonal complexes. The MenW isolates (n = 10) comprised cc11 (n = 5), ST-2754 (cc-unassigned; n = 4) and cc22 (n = 1). gMATS was indicative of high 4CMenB coverage (72.2-79.1%) of Turkish invasive MenB strains from pediatric patients. Strain coverage of several clonal complexes differed from that seen elsewhere in Europe highlighting the importance of performing local assessments and also the use of phenotypic methods, i.e. MATS, where possible. All of the isolates possessed in-frame fhbp alleles and so were potentially covered by MenB-fHbp. Continued surveillance is essential to guide recommendations for current and future vaccines as well as understanding changes in epidemiology.
MeSH term(s)	Adolescent ; Antigens, Bacterial/genetics ; Child ; Child, Preschool ; Europe ; Humans ; Infant ; Infant, Newborn ; Meningococcal Infections/epidemiology ; Meningococcal Vaccines ; Multilocus Sequence Typing ; Neisseria meningitidis/genetics ; Neisseria meningitidis, Serogroup B/genetics ; Serogroup ; Turkey/epidemiology
Chemical Substances	Antigens, Bacterial ; Meningococcal Vaccines
Language	English
Publishing date	2020-03-19
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2020.03.024
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Zs.A 1930: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 458: Show issues

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Article ; Online: The knowledge of cervical length is essential in decision making for cervical cerclage.

Api, Olus / Api, Murat / Ceyhan, Mehmet

American journal of obstetrics and gynecology

2020 Volume 224, Issue 5, Page(s) 543

MeSH term(s)	Cerclage, Cervical ; Cervix Uteri/diagnostic imaging ; Cervix Uteri/surgery ; Decision Making ; Female ; Humans ; Physical Examination ; Pregnancy ; Pregnancy, Twin ; Uterine Cervical Incompetence/surgery
Language	English
Publishing date	2020-11-20
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	80016-8
ISSN	1097-6868 ; 0002-9378
ISSN (online)	1097-6868
ISSN	0002-9378
DOI	10.1016/j.ajog.2020.11.026
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Article: Characterization of invasive Neisseria meningitidis isolates recovered from children in Turkey during a period of increased serogroup B disease, 2013–2017

Ceyhan, Mehmet / Ozsurekci, Yasemin / Lucidarme, Jay / Borrow, Ray

Elsevier Ltd Vaccine. 2020 Apr. 23, v. 38, no. 19

2020

Institution	Meningitis Surveillance Group
Abstract	Diverse Neisseria meningitidis strains belonging to various serogroups and clonal complexes cause epidemic and endemic life-threatening disease worldwide. This study aimed to investigate the genetic diversity of recent invasive meningococci in Turkey with respect to multilocus sequence type (MLST) and also meningococcal serogroup B (MenB) vaccine antigens to enable assessment of potential MenB strain coverage using the genetic Meningococcal Antigen Typing System (gMATS). Fifty-four isolates, representing 37.5% of all pediatric (ages 0–18 years) invasive meningococcal disease cases in Turkey from January 2013 to December 2017, underwent genome sequence analysis. Thirty-six (66.7%) isolates were MenB, 10 (18.5%) were serogroup W (MenW), 4 (7.4%) were serogroup A (MenA), 3 (5.6%) were serogroup Y (MenY) and 1 (1.8%) was serogroup X (MenX). The MenB isolates were diverse with cc35 (19.4%), cc41/44 (19.4%) and cc32 (13.8%) as the most prevalent clonal complexes. The MenW isolates (n = 10) comprised cc11 (n = 5), ST-2754 (cc-unassigned; n = 4) and cc22 (n = 1). gMATS was indicative of high 4CMenB coverage (72.2–79.1%) of Turkish invasive MenB strains from pediatric patients. Strain coverage of several clonal complexes differed from that seen elsewhere in Europe highlighting the importance of performing local assessments and also the use of phenotypic methods, i.e. MATS, where possible. All of the isolates possessed in-frame fhbp alleles and so were potentially covered by MenB-fHbp. Continued surveillance is essential to guide recommendations for current and future vaccines as well as understanding changes in epidemiology.
Keywords	Neisseria meningitidis ; alleles ; children ; epidemiology ; monitoring ; patients ; phenotype ; serotypes ; vaccines ; Turkey (country)
Language	English
Dates of publication	2020-0423
Size	p. 3545-3552.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2020.03.024
Database	NAL-Catalogue (AGRICOLA)

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Article: Recent improvements in the Turkish Childhood National Immunization Program.

Ceyhan, Mehmet

The Turkish journal of pediatrics

2010 Volume 52, Issue 6, Page(s) 563–569

Abstract: The Childhood National Immunization Program (NIP) is a key element of the primary healthcare and plays a major role in the national health status. The Turkish NIP, which is run by the Ministry of Health, included mainly the basic vaccines (Bacillus ... ...

Abstract	The Childhood National Immunization Program (NIP) is a key element of the primary healthcare and plays a major role in the national health status. The Turkish NIP, which is run by the Ministry of Health, included mainly the basic vaccines (Bacillus Calmette-Guerin [BCG], diphtheria-pertussis-tetanus [DPT], polio, measles) until 2005. However, a change in the governmental policies in 2002 and a close collaboration with the Advisory Board of Immunization have improved the Turkish NIP not only in terms of the quality of the vaccines and vaccination rates but also the number of pathogens covered. Currently, Turkey has a NIP that is equivalent to or better than that of the other European countries. However, making vaccination a constant part and priority of the state health policies is necessary for sustainability. Political commitment and efficient multi-sectorial collaboration and awareness are crucial.
MeSH term(s)	Child ; Child Welfare ; Decision Making ; Health Policy ; Humans ; Immunization Programs/organization & administration ; Immunization Programs/statistics & numerical data ; Turkey ; Vaccination/statistics & numerical data
Language	English
Publishing date	2010-11
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	123487-0
ISSN	0041-4301
ISSN	0041-4301
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Article ; Online: Characteristics and Management of Children With COVID-19 in a Tertiary Care Hospital in Turkey.

Yayla, Burcu Ceylan Cura / Aykac, Kubra / Ozsurekci, Yasemin / Ceyhan, Mehmet

Clinical pediatrics

2020 Volume 60, Issue 3, Page(s) 170–177

Abstract: Introduction: Limited data are available for pediatric patients with coronavirus disease 2019 (COVID-19), especially with regard to disease management strategies.: Objective: To assess the children with COVID-19.: Method: We conducted a ... ...

Abstract	Introduction: Limited data are available for pediatric patients with coronavirus disease 2019 (COVID-19), especially with regard to disease management strategies. Objective: To assess the children with COVID-19. Method: We conducted a retrospective review of the medical records of pediatric patients on March 11 and May 23, 2020. Results: We evaluated 77 COVID-19 pediatric patients, of whom 45.5% were male, with a median age of 8 years (interquartile range [IQR] = 2-13), and 6.4% had underlying diseases. Patients were classified according to severity, with the percentages of asymptomatic, mild, moderate, and critical/severe cases determined to be 24.7%, 41.6%, 29.9%, and 3.9%, respectively. Extracorporeal membrane oxygenation and mechanic ventilation were only required for 1 patient. Targeted therapies were used in 3 patients. Conclusion: The disease course of COVID-19 appears to be milder in children than in adults, and the treatment course primarily consists of supportive care.
MeSH term(s)	Adolescent ; Amides ; Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; COVID-19/pathology ; COVID-19/physiopathology ; Child ; Child, Preschool ; Female ; Humans ; Hydroxychloroquine ; Immunoglobulins, Intravenous/therapeutic use ; Lung/pathology ; Lung/physiopathology ; Male ; Pediatrics/methods ; Pyrazines ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index ; Tertiary Care Centers ; Treatment Outcome ; Turkey
Chemical Substances	Amides ; Antiviral Agents ; Immunoglobulins, Intravenous ; Pyrazines ; Hydroxychloroquine (4QWG6N8QKH) ; favipiravir (EW5GL2X7E0)
Keywords	covid19
Language	English
Publishing date	2020-10-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	207678-0
ISSN	1938-2707 ; 0009-9228
ISSN (online)	1938-2707
ISSN	0009-9228
DOI	10.1177/0009922820966306
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Zs.A 454: Show issues

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Article: Pneumococcal seroepidemiology in Turkey.

Ceyhan, Mehmet

Vaccine

2008 Volume 26, Issue 52, Page(s) 6745

MeSH term(s)	Carrier State ; Child ; Humans ; Immunization Programs ; Infant ; Infant, Newborn ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/immunology ; Pneumococcal Infections/transmission ; Pneumococcal Vaccines/therapeutic use ; Serotyping ; Turkey/epidemiology
Chemical Substances	Pneumococcal Vaccines
Language	English
Publishing date	2008-12-09
Publishing country	Netherlands
Document type	Comment ; Letter
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2008.10.005
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Article ; Online: Molecular characteristics of Staphylococcus aureus strains isolated from nasal samples of sixth year medical students during their pediatric services practices.

Arıkan, Kamile / Karadag-Oncel, Eda / Aycan, Emre / Sancak, Banu / Ceyhan, Mehmet

Annals of clinical microbiology and antimicrobials

2021 Volume 20, Issue 1, Page(s) 25

Abstract: Background: Methicillin-resistant Staphylococcus aureus (MRSA) strains are prevalent in healthcare services. Medical students are at risk for MRSA carriage, subsequent infection and potential transmission of nosocomial infection.Few studies have ... ...

Abstract	Background: Methicillin-resistant Staphylococcus aureus (MRSA) strains are prevalent in healthcare services. Medical students are at risk for MRSA carriage, subsequent infection and potential transmission of nosocomial infection.Few studies have examined MRSA carriage among medical students. Methods: In this prospective cohort study, between July 2016 and June 2017, two nasal swab samples were taken per student 4 weeks apart during their pediatric internship. MRSA typing was performed by staphylococcal cassette chromosome mec (SCCmec) types, Panton Valentine leukocidin (PVL) encoding genes. Results: A total of 239 sixth year medical students, 164 (68.6%) male (M/F:2.1),with median age 25 years (min-max; 23-65 years) were included in this prospective cohort study. Among 239 students, 17 students (7.1%) were found to be colonized with methicillin-sensitive S. aureus (MSSA) at the beginning of pediatric internship. After 4 weeks, at the end of pediatric internship totally 52 students were found to be S. aureus colonized (21.8%). Three of 52 S. aureus isolates were MRSA (1.3%) and the rest was MSSA (20.5%), all were PVL gen negative. Two of three MRSA isolates were characterized as SCCmec type IV, one isolate was untypeable SCCmec. Nasal carriage of S. aureus increased from 7.1% to 21.5% (p < 0.001). Nasal S. aures colonization ratio was higher in students working in pediatric infectious disease service (p = 0.046). Smoking was found to be associated with a 2.37-fold [95% CI (1.12-5.00); p = 0.023] and number of patients in pediatric services was 2.66-fold [95% CI (1.13-6.27); p = 0.024] increase the risk of nasal S. aureus colonization. Gender was not found to increase risk of MRSA carriage. Conclusion: MSSA nasal carriage increased at the end of pediatric internship and significantly high in students working in pediatric infectious diseases services. Smoking and high number of patients in pediatric services significantly increase S.aureus colonization.
MeSH term(s)	Adult ; Aged ; Bacterial Toxins ; Child ; Cross Infection/microbiology ; Exotoxins ; Female ; Humans ; Leukocidins ; Male ; Methicillin-Resistant Staphylococcus aureus/genetics ; Methicillin-Resistant Staphylococcus aureus/isolation & purification ; Middle Aged ; Prospective Studies ; Staphylococcal Infections ; Staphylococcus aureus/genetics ; Staphylococcus aureus/isolation & purification ; Students, Medical ; Young Adult
Chemical Substances	Bacterial Toxins ; Exotoxins ; Leukocidins ; Panton-Valentine leukocidin
Language	English
Publishing date	2021-04-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2097873-X
ISSN	1476-0711 ; 1476-0711
ISSN (online)	1476-0711
ISSN	1476-0711
DOI	10.1186/s12941-021-00429-8
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