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  1. Article ; Online: Mepitel Film for the prevention of acute radiation dermatitis in breast cancer patients: a discussion of recent findings.

    Chakraborty, Molly A / Hill, Rosemary / Corbin, Kimberly / Perlmutter, Jane / Wright, Jean L / Choi, J Isabelle

    Annals of palliative medicine

    2023  Volume 12, Issue 6, Page(s) 1469–1474

    Language English
    Publishing date 2023-10-21
    Publishing country China
    Document type Journal Article
    ZDB-ID 2828544-X
    ISSN 2224-5839 ; 2224-5839
    ISSN (online) 2224-5839
    ISSN 2224-5839
    DOI 10.21037/apm-23-536
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Proton Reirradiation for High-Risk Recurrent or New Primary Breast Cancer.

    Chakraborty, Molly A / Khan, Atif J / Cahlon, Oren / Xu, Amy J / Braunstein, Lior Z / Powell, Simon N / Choi, J Isabelle

    Cancers

    2023  Volume 15, Issue 24

    Abstract: Radiotherapy is an integral component of multidisciplinary breast cancer care. Given how commonly radiotherapy is used in the treatment of breast cancer, many patients with recurrences have received previous radiotherapy. Patients with new primary breast ...

    Abstract Radiotherapy is an integral component of multidisciplinary breast cancer care. Given how commonly radiotherapy is used in the treatment of breast cancer, many patients with recurrences have received previous radiotherapy. Patients with new primary breast cancer may also have received previous radiotherapy to the thoracic region. Curative doses and comprehensive field photon reirradiation (reRT) have often been avoided in these patients due to concerns for severe toxicities to organs-at-risk (OARs), such as the heart, lungs, brachial plexus, and soft tissue. However, many patients may benefit from definitive-intent reRT, such as patients with high-risk disease features such as lymph node involvement and dermal/epidermal invasion. Proton therapy is a potentially advantageous treatment option for delivery of reRT due to its lack of exit dose and greater conformality that allow for enhanced non-target tissue sparing of previously irradiated tissues. In this review, we discuss the clinical applications of proton therapy for patients with breast cancer requiring reRT, the currently available literature and how it compares to historical photon reRT outcomes, treatment planning considerations, and questions in this area warranting further study. Given the dosimetric advantages of protons and the data reported to date, proton therapy is a promising option for patients who would benefit from the added locoregional disease control provided by reRT for recurrent or new primary breast cancer.
    Language English
    Publishing date 2023-12-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15245722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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