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  1. Article ; Online: The prostatic middle lobe: clinical significance, presentation and management.

    Gharbieh, Sammy / Reeves, Fairleigh / Challacombe, Ben

    Nature reviews. Urology

    2023  Volume 20, Issue 11, Page(s) 645–653

    Abstract: The role of the prostatic middle lobe in the presentation and management of benign prostatic hyperplasia (BPH) is under-appreciated. Middle lobe enlargement is associated with intravesical prostatic protrusion (IPP), which causes a unique type of bladder ...

    Abstract The role of the prostatic middle lobe in the presentation and management of benign prostatic hyperplasia (BPH) is under-appreciated. Middle lobe enlargement is associated with intravesical prostatic protrusion (IPP), which causes a unique type of bladder outlet obstruction (BOO) via a 'ball-valve' mechanism. IPP is a reliable predictor of BOO and the strongest independent factor for failure of medical therapy necessitating conversion to surgical intervention. Men with middle lobe enlargement tend to exhibit mixed symptoms of both the storage and the voiding types, but symptomatology will vary depending on the degree of IPP present. Initial assessments such as uroflowmetry and post-void residual volumes are inadequate to detect IPP and could confound the clinical picture. Radiological evaluation of prostate morphology is key to assessment as it provides important prognostic information and can help with operative planning. Treatment strategies employed for BPH should consider the shape and morphology of prostate adenomata, specifically the presence of middle lobe enlargement and the degree of associated IPP.
    MeSH term(s) Male ; Humans ; Prostate/diagnostic imaging ; Prostate/surgery ; Prostatic Hyperplasia/diagnosis ; Prostatic Hyperplasia/diagnostic imaging ; Clinical Relevance ; Ultrasonography/adverse effects ; Urinary Bladder Neck Obstruction/diagnostic imaging ; Urinary Bladder Neck Obstruction/etiology ; Hypertrophy
    Language English
    Publishing date 2023-05-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2493737-X
    ISSN 1759-4820 ; 1759-4812
    ISSN (online) 1759-4820
    ISSN 1759-4812
    DOI 10.1038/s41585-023-00774-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: How to Deal with Renal Cell Carcinoma Tumours >7 cm: Referee.

    Abu-Ghanem, Yasmin / Challacombe, Ben

    European urology open science

    2021  Volume 33, Page(s) 45–47

    Language English
    Publishing date 2021-09-27
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-1683
    ISSN (online) 2666-1683
    DOI 10.1016/j.euros.2021.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Intuitive's da Vinci vs Medtronic's Hugo: real life observations from a robot naïve perspective.

    Atife, Michael / Okondo, Esele / Jaffer, Ata / Noel, Jonathan / Dasgupta, Prokar / Challacombe, Ben

    Journal of robotic surgery

    2024  Volume 18, Issue 1, Page(s) 4

    MeSH term(s) Humans ; Robotics ; Robotic Surgical Procedures/methods
    Language English
    Publishing date 2024-01-09
    Publishing country England
    Document type Letter
    ZDB-ID 2268283-1
    ISSN 1863-2491 ; 1863-2483
    ISSN (online) 1863-2491
    ISSN 1863-2483
    DOI 10.1007/s11701-023-01763-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Superior Mesenteric Artery Injury During Robot-assisted Laparoscopic Nephrectomy: A Robotic Nightmare.

    Mayor, Nikhil / Sapre, Nikhil / Sandford, Becky / Challacombe, Ben

    European urology open science

    2022  Volume 38, Page(s) 44–48

    Abstract: Major vascular injuries during robotic renal surgery are rare, but the close proximity of the superior mesenteric artery (SMA) to the left renal artery means that it is liable to iatrogenic injury with potentially catastrophic implications. In this ... ...

    Abstract Major vascular injuries during robotic renal surgery are rare, but the close proximity of the superior mesenteric artery (SMA) to the left renal artery means that it is liable to iatrogenic injury with potentially catastrophic implications. In this review, we present a case of accidental SMA ligation during a robot-assisted laparoscopic nephrectomy for a 12-cm upper pole renal mass. Prompt recognition and early vascular surgical assistance with conversion to open surgery allowed a primary vascular anastomosis to be made. A computed tomography angiogram at 6 wk was normal. On review of the imaging, the left renal artery take-off was higher than the SMA, which represents an anatomical variant and may have contributed to the injury. The risk of accidental SMA ligation is highest in left-sided tumours and in larger medial tumours that lead to significant distortion of the anatomy. The anatomy of the renal artery can also vary greatly. Surgeons must be knowledgeable of common variations and meticulously review preoperative imaging for the number and course of renal vessels as well as the location of the SMA. In cases of significant bleeding, rapid conversion to open surgery and urgent vascular consultation are critical.
    Patient summary: In this article, we describe an accidental injury to a major blood vessel (the superior mesenteric artery) during a left robotic radical nephrectomy (kidney removal) for a tumour. We discuss the anatomical relationships of the blood vessels of the small bowel and kidneys, and how to anticipate, recognise, and manage such accidental injuries.
    Language English
    Publishing date 2022-02-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 3040546-4
    ISSN 2666-1683 ; 2058-4881
    ISSN (online) 2666-1683
    ISSN 2058-4881
    DOI 10.1016/j.euros.2022.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Here comes the sun.

    Challacombe, Ben

    BJU international

    2015  Volume 116, Issue 2, Page(s) 163

    MeSH term(s) Humans ; Leisure Activities ; Urologic Surgical Procedures ; Urology/organization & administration
    Language English
    Publishing date 2015-08
    Publishing country England
    Document type Editorial
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/bju.13217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Idea, Development, Exploration, Assessment, Long-term follow-up study (IDEAL) Stage 1/2a evaluation of urological procedures with the Versius robot.

    Reeves, Fairleigh / Challacombe, Ben / Ribbits, Alexander / Ourselin, Sebastien / Dasgupta, Prokar

    BJU international

    2022  Volume 130, Issue 4, Page(s) 441–443

    MeSH term(s) Follow-Up Studies ; Humans ; Robotics
    Language English
    Publishing date 2022-07-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/bju.15829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Metastasectomy in renal cell carcinoma: where are we now?

    Lloyd, Alexander / Reeves, Fairleigh / Abu-Ghanem, Yasmin / Challacombe, Ben

    Current opinion in urology

    2022  Volume 32, Issue 6, Page(s) 627–633

    Abstract: Purpose of review: Metastatic RCC has a variable natural history. Treatment choice depends on disease and patient factors, but most importantly disease burden and site of metastasis. This article highlights key variables to consider when contemplating ... ...

    Abstract Purpose of review: Metastatic RCC has a variable natural history. Treatment choice depends on disease and patient factors, but most importantly disease burden and site of metastasis. This article highlights key variables to consider when contemplating metastasectomy for RCC and provide a narrative review on the evidence for metastasectomy in these patients.
    Recent findings: Tumour subtype is associated with differing patterns of recurrence. Patients with single or few metastatic sites have better outcomes, and those with greater time interval from initial nephrectomy. Local recurrence is particularly amenable to minimally invasive surgical resection and is oncologically sound. Very well selected cases of liver or brain metastases may benefit from metastectomy, although lung and endocrine metastases have more favourable outcomes. Although site and burden of disease is important, the key determinate of outcome in metastasectomy depends mostly on the ability to achieve a complete resection. Adjuvant treatment is not currently advocated.
    Summary: Metastasectomy should be generally reserved for cases where complete resection is achievable, unless the goal of treatment is to palliate symptoms. This field warrants ongoing research, particularly as systemic therapy and minimally invasive surgical techniques evolve. Elucidating tumour biology to inform patient selection will be important in future research.
    MeSH term(s) Carcinoma, Renal Cell/therapy ; Humans ; Kidney Neoplasms/pathology ; Metastasectomy/adverse effects ; Metastasectomy/methods ; Nephrectomy ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-09-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1091792-5
    ISSN 1473-6586 ; 0963-0643
    ISSN (online) 1473-6586
    ISSN 0963-0643
    DOI 10.1097/MOU.0000000000001042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Both sides of the scalpel: the patient and the surgeon view.

    Fry, Stephen / Challacombe, Ben

    Nature reviews. Urology

    2019  Volume 16, Issue 3, Page(s) 153–158

    Abstract: As clinicians and surgeons, the experience of prostate cancer is one that happens on an almost daily basis. We are used to the feeling of making a diagnosis, to reassuring our patients, to the calm and sterility of an operating theatre, and to the worry ... ...

    Abstract As clinicians and surgeons, the experience of prostate cancer is one that happens on an almost daily basis. We are used to the feeling of making a diagnosis, to reassuring our patients, to the calm and sterility of an operating theatre, and to the worry of waiting for pathology results. For our patients, this experience is new and often terrifying, and only rarely do we consider the two experiences - doctor and patient - together. If we are to ask a patient to tell their story in writing, there are few people who are better placed to do so than one who does this professionally and who has done so for the best part of four decades. In this Viewpoint, Stephen Fry describes his prostate cancer journey from initial concerns through diagnosis and surgery to follow-up, alongside the same story told by his surgeon, Ben Challacombe. Thus, this unique article reminds us that the same events provide a different experience for patient and surgeon and enables us to consider both sides of the scalpel.
    MeSH term(s) Attitude of Health Personnel ; Attitude to Health ; Humans ; Male ; Prostatic Neoplasms/surgery ; Urology
    Language English
    Publishing date 2019-02-18
    Publishing country England
    Document type Journal Article ; Personal Narrative
    ZDB-ID 2493737-X
    ISSN 1759-4820 ; 1759-4812
    ISSN (online) 1759-4820
    ISSN 1759-4812
    DOI 10.1038/s41585-019-0153-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Ben Challacombe in defence of robots.

    Challacombe, Ben

    The Health service journal

    2013  Volume 123, Issue 6378, Page(s) 16–17

    MeSH term(s) Humans ; Medical Errors/adverse effects ; Medical Errors/prevention & control ; Robotics/standards ; Robotics/trends ; State Medicine/standards ; State Medicine/trends ; Surgical Procedures, Operative/adverse effects ; Surgical Procedures, Operative/methods ; Surgical Procedures, Operative/trends ; United Kingdom
    Language English
    Publishing date 2013-12-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 632799-0
    ISSN 0952-2271 ; 0300-8347
    ISSN 0952-2271 ; 0300-8347
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: HoLEP: is it coming of age?

    Challacombe, Ben

    BJU international

    2013  Volume 112, Issue 7, Page(s) 879–880

    MeSH term(s) Humans ; Laser Therapy ; Lasers, Solid-State/therapeutic use ; Lower Urinary Tract Symptoms/surgery ; Male ; Prostatectomy/methods ; Prostatic Hyperplasia/surgery
    Language English
    Publishing date 2013-11
    Publishing country England
    Document type Comment ; Editorial
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/bju.12323
    Database MEDical Literature Analysis and Retrieval System OnLINE

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