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  1. Article: PDAL: An open source library for the processing and analysis of point clouds

    Butler, Howard / Chambers, Bradley / Hartzell, Preston / Glennie, Craig

    Elsevier Ltd Computers & geosciences. 2021 Mar., v. 148

    2021  

    Abstract: As large point cloud datasets become ubiquitous in the Earth science community, open source libraries and software dedicated to manipulating these data are valuable tools for geospatial scientists and practitioners. We highlight an open source library ... ...

    Abstract As large point cloud datasets become ubiquitous in the Earth science community, open source libraries and software dedicated to manipulating these data are valuable tools for geospatial scientists and practitioners. We highlight an open source library called the Point Data Abstraction Library, more commonly referred to by its acronym: PDAL. PDAL provides a standalone application for point cloud processing, a C++ library for development of new point cloud applications, and support for Python, MATLAB, Julia, and Java languages. Central to PDAL are the concepts of stages, which implement core capabilities for reading, writing, and filtering point cloud data, and pipelines, which are end-to-end workflows composed of sequential stages for transforming point clouds. We review the motivation for PDAL’s genesis, describe its general structure and functionality, detail several options for conveniently accessing PDAL’s functionality, and provide an example that uses PDAL’s Python extension to estimate earthquake surface deformation from pre- and post-event airborne laser scanning point cloud data using an iterative closest point algorithm.
    Keywords Python ; algorithms ; computer software ; data collection ; deformation ; earthquakes ; motivation
    Language English
    Dates of publication 2021-03
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ISSN 0098-3004
    DOI 10.1016/j.cageo.2020.104680
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Atezolizumab-induced autoimmune haemolytic anaemia caused by drug-independent antibodies.

    Chambers, Bradley S / Ward, David / Webster, Robert / Tunnard, Valerie / Hill, Quentin A

    European journal of cancer (Oxford, England : 1990)

    2022  Volume 162, Page(s) 158–160

    MeSH term(s) Anemia, Hemolytic, Autoimmune/chemically induced ; Antibodies, Monoclonal, Humanized/adverse effects ; Humans
    Chemical Substances Antibodies, Monoclonal, Humanized ; atezolizumab (52CMI0WC3Y)
    Language English
    Publishing date 2022-01-05
    Publishing country England
    Document type Letter
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/j.ejca.2021.11.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 456: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 583: Show issues

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  3. Article ; Online: Cardiac Magnetic Resonance Left Ventricular Filling Pressure Is Associated with NT-proBNP in Patients with New Onset Heart Failure.

    Assadi, Hosamadin / Matthews, Gareth / Chambers, Bradley / Grafton-Clarke, Ciaran / Shabi, Mubien / Plein, Sven / Swoboda, Peter P / Garg, Pankaj

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 11

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Humans ; Natriuretic Peptide, Brain ; Heart Failure ; Magnetic Resonance Imaging ; Stroke Volume/physiology ; Prognosis ; Magnetic Resonance Spectroscopy ; Biomarkers
    Chemical Substances pro-brain natriuretic peptide (1-76) ; Natriuretic Peptide, Brain (114471-18-0) ; Biomarkers
    Language English
    Publishing date 2023-10-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59111924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Cardiac magnetic resonance left ventricular filling pressure is linked to symptoms, signs and prognosis in heart failure.

    Grafton-Clarke, Ciaran / Garg, Pankaj / Swift, Andrew J / Alabed, Samer / Thomson, Ross / Aung, Nay / Chambers, Bradley / Klassen, Joel / Levelt, Eylem / Farley, Jonathan / Greenwood, John P / Plein, Sven / Swoboda, Peter P

    ESC heart failure

    2023  Volume 10, Issue 5, Page(s) 3067–3076

    Abstract: Aims: Left ventricular filling pressure (LVFP) can be estimated from cardiovascular magnetic resonance (CMR). We aimed to investigate whether CMR-derived LVFP is associated with signs, symptoms, and prognosis in patients with recently diagnosed heart ... ...

    Abstract Aims: Left ventricular filling pressure (LVFP) can be estimated from cardiovascular magnetic resonance (CMR). We aimed to investigate whether CMR-derived LVFP is associated with signs, symptoms, and prognosis in patients with recently diagnosed heart failure (HF).
    Methods and results: This study recruited 454 patients diagnosed with HF who underwent same-day CMR and clinical assessment between February 2018 and January 2020. CMR-derived LVFP was calculated, as previously, from long- and short-axis cines. CMR-derived LVFP association with symptoms and signs of HF was investigated. Patients were followed for median 2.9 years (interquartile range 1.5-3.6 years) for major adverse cardiovascular events (MACE), defined as the composite of cardiovascular death, HF hospitalization, non-fatal stroke, and non-fatal myocardial infarction. The mean age was 62 ± 13 years, 36% were female (n = 163), and 30% (n = 135) had raised LVFP. Forty-seven per cent of patients had an ejection fraction < 40% during CMR assessment. Patients with raised LVFP were more likely to have pleural effusions [hazard ratio (HR) 3.2, P = 0.003], orthopnoea (HR 2.0, P = 0.008), lower limb oedema (HR 1.7, P = 0.04), and breathlessness (HR 1.7, P = 0.01). Raised CMR-derived LVFP was associated with a four-fold risk of HF hospitalization (HR 4.0, P < 0.0001) and a three-fold risk of MACE (HR 3.1, P < 0.0001). In the multivariable model, raised CMR-derived LVFP was independently associated with HF hospitalization (adjusted HR 3.8, P = 0.0001) and MACE (adjusted HR 3.0, P = 0.0001).
    Conclusions: Raised CMR-derived LVFP is strongly associated with symptoms and signs of HF. In addition, raised CMR-derived LVFP is independently associated with subsequent HF hospitalization and MACE.
    MeSH term(s) Humans ; Female ; Middle Aged ; Aged ; Male ; Ventricular Function, Left ; Stroke Volume ; Prospective Studies ; Heart Failure/diagnosis ; Prognosis ; Magnetic Resonance Spectroscopy
    Language English
    Publishing date 2023-08-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2814355-3
    ISSN 2055-5822 ; 2055-5822
    ISSN (online) 2055-5822
    ISSN 2055-5822
    DOI 10.1002/ehf2.14499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reinstating Elective Surgeries in MedStar Health: A Roadmap for Healthcare Organizations.

    Stein, David E / Chia, Stanley H / Breakey, Thomas H / Song, David H / Woo, Edward Y / Fairbanks, Rollin J / Jordan, David / Curl, Leigh Ann / Boucher, Henry R / Boyle, Lisa / Edwards, Karol / Friedrich, Hanna / Gilbert, Robert J / Matton, Jeffrey / Mucci, Kathy / Chambers, Bradley / Sachtleben, Michael / Watson, Thomas J

    Annals of surgery open : perspectives of surgical history, education, and clinical approaches

    2020  Volume 1, Issue 1, Page(s) e002

    Abstract: Introduction: Coronavirus disease 2019 (COVID-19) infections have strained hospital resources worldwide. As a result, many facilities have suspended elective operations and ambulatory procedures. As the incidence of new cases of COVID-19 decreases, ... ...

    Abstract Introduction: Coronavirus disease 2019 (COVID-19) infections have strained hospital resources worldwide. As a result, many facilities have suspended elective operations and ambulatory procedures. As the incidence of new cases of COVID-19 decreases, hospitals will need policies and algorithms to facilitate safe and orderly return of normal activities. We describe the recommendations of a task force established in a multi-institutional healthcare system for resumption of elective operative and ambulatory procedures applicable to all hospitals and service lines.
    Methods: MedStar Health created a multidisciplinary task force to develop guidelines for resumption of elective surgeries/procedures. The primary focus areas included the establishment of a governance structure at each healthcare facility, prioritization of elective cases, preoperative severe acute respiratory syndrome coronavirus 2 testing, and an assessment of the needs and availability of staff, personal protective equipment, and other essential resources.
    Results: Each hospital president was tasked with establishing a local perioperative leadership team answering directly to them and granted the authority to prioritize elective surgery and ambulatory procedures. An elective surgery algorithm was established using a simplified Medically Necessary Time Sensitive score, with multiple steps requiring a "go/no-go" assessment based on local resources. In addition, mandatory preoperative COVID testing policies were developed and operationalized.
    Conclusions: Even when the COVID pandemic has passed, hospitals and surgical centers will require COVID screening and testing, case prioritization, and supply chain management to provide care essential to the surgical patient while protecting their safety and that of staff. Our guidelines consider these factors and are applicable to both tertiary academic medical centers and smaller community facilities.
    Language English
    Publishing date 2020-08-11
    Publishing country United States
    Document type Journal Article
    ISSN 2691-3593
    ISSN (online) 2691-3593
    DOI 10.1097/AS9.0000000000000002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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