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  1. Article ; Online: Bone broth ingestion and acute kidney injury following kidney transplant: a role for cystatin C.

    Chandler, Shaun / Viswanathan, Shankar / Sartain, Felicity / John, George Tharayil

    BMJ case reports

    2024  Volume 17, Issue 2

    Abstract: Measurement of graft dysfunction following kidney transplant through creatinine is well known to be impacted by many different factors. We report here a clinical scenario demonstrating the importance of dual measurement of glomerular filtration rate (GFR) ...

    Abstract Measurement of graft dysfunction following kidney transplant through creatinine is well known to be impacted by many different factors. We report here a clinical scenario demonstrating the importance of dual measurement of glomerular filtration rate (GFR) based on creatinine and cystatin C while also examining within-subject variability of both tests.
    MeSH term(s) Humans ; Acute Kidney Injury/blood ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/etiology ; Biomarkers ; Creatinine ; Cystatin C ; Glomerular Filtration Rate ; Kidney Transplantation ; Food/adverse effects
    Chemical Substances Biomarkers ; Creatinine (AYI8EX34EU) ; Cystatin C
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-256431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Creatinine index: a retrospective cohort study in an urban Australian dialysis context.

    Chandler, Shaun / MacLaughlin, Helen / Wolley, Martin

    Internal medicine journal

    2023  Volume 53, Issue 12, Page(s) 2291–2297

    Abstract: Aim: This study aimed to described the relationship between the CI and mortality in an Australian context.: Introduction: Maintenance haemodialysis is a catabolic state associated with a significant decrease in lean body mass (LBM) and protein energy ...

    Abstract Aim: This study aimed to described the relationship between the CI and mortality in an Australian context.
    Introduction: Maintenance haemodialysis is a catabolic state associated with a significant decrease in lean body mass (LBM) and protein energy wasting. LBM can be derived or estimated from creatinine kinetic modelling, specifically the creatinine index (CI). This has been demonstrated in cohort studies to predict mortality.
    Methods: One hundred seventy-nine patients undergoing haemodialysis in 2015 were included in this cohort. They were followed for 5 years with pertinent clinical data collected to calculate the CI as of December 2015. For analysis, patients were split into a high and low CI group based on the median (18.32 mg/kg/day). The primary outcome of interest was all-cause mortality, and secondary outcomes included myocardial infarction, stroke and transplantation.
    Results: During follow-up, 69 (76.7%) patients in the low CI group and 28 (31.5%) patients in the high CI group died (P < 0.001). The relative risk (RR) of mortality within the low compared with the high CI group was 2.43 (95% confidence interval, 1.75-3.38). Fully adjusted Cox proportional hazards modelling demonstrated a hazard ratio (HR) of 0.498 (95% CI, 0.292-0.848) for survival in the high CI group. Lower CI was associated with increased risk of stroke (RR, 5.43 [95% CI, 1.24-23.84]), whereas transplant was more likely in the high CI group (RR, 6.4 [95% confidence interval, 1.96-20.88]).
    Conclusions: In a single-centre Australian haemodialysis cohort, the CI was strongly associated with mortality and stroke risk. The CI is an accurate and simple method to identify patients with low LBM at risk for significant morbidity and mortality.
    MeSH term(s) Humans ; Renal Dialysis ; Creatinine ; Retrospective Studies ; Australia/epidemiology ; Cohort Studies ; Stroke/epidemiology
    Chemical Substances Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2023-03-31
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.16054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 792: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 424: Show issues

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  3. Article ; Online: Snake envenomation: not your average acute kidney injury.

    Chandler, Shaun / Isoardi, Katherine / Ng, Samantha

    Internal medicine journal

    2022  Volume 52, Issue 8, Page(s) 1446–1447

    MeSH term(s) Acute Kidney Injury/etiology ; Animals ; Humans ; Snake Bites/complications ; Snake Bites/therapy ; Snakes
    Language English
    Publishing date 2022-08-13
    Publishing country Australia
    Document type Letter
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.15879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 792: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 424: Show issues

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  4. Article ; Online: Should we biopsy?

    Chandler, Shaun / Oliver, Kimberly / Tan, Ken-Soon / Palamuthusingam, Dharmenaan

    Internal medicine journal

    2021  Volume 51, Issue 8, Page(s) 1359–1360

    Language English
    Publishing date 2021-08-23
    Publishing country Australia
    Document type Letter
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.15454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 792: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  5. Article ; Online: Sodium chlorite poisoning: a case of severe methaemoglobinaemia and dialysis-requiring kidney injury.

    Tunbridge, Matthew / Chandler, Shaun / Isbel, Nicole / Jegatheesan, Dev / McNeill, Iain R / Isoardi, Katherine / Viecelli, Andrea K

    Internal medicine journal

    2022  Volume 52, Issue 8, Page(s) 1452–1453

    MeSH term(s) Acute Kidney Injury/chemically induced ; Acute Kidney Injury/therapy ; Chlorides ; Humans ; Kidney ; Methemoglobinemia/chemically induced ; Methemoglobinemia/diagnosis ; Poisoning ; Renal Dialysis
    Chemical Substances Chlorides ; chlorite (Z63H374SB6)
    Language English
    Publishing date 2022-08-13
    Publishing country Australia
    Document type Case Reports ; Letter
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.15870
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 792: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 424: Show issues

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