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  1. Article: A Case Report of Congenital Afibrinogenemia and Literature Review of Management of Post-circumcision Bleeding.

    Khan, Imteyaz / Chow, Matthew / Chandra, Shakuntala / Hiatt, Mark

    Cureus

    2023  Volume 15, Issue 3, Page(s) e36459

    Abstract: We present a case of bleeding from circumcision in a full-term newborn male resulting from a rare coagulopathy, congenital afibrinogenemia, and a review of the literature regarding the management of bleeding after circumcision. Bleeding was managed with ... ...

    Abstract We present a case of bleeding from circumcision in a full-term newborn male resulting from a rare coagulopathy, congenital afibrinogenemia, and a review of the literature regarding the management of bleeding after circumcision. Bleeding was managed with silver nitrate, suturing, thrombin powder, Arista
    Language English
    Publishing date 2023-03-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.36459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Case 6: Seizures and Low Cerebrospinal Fluid Glucose in a 4-day-old Boy.

    Belal, Tarek / Day-Salvatore, Debra-Lynn / Chandra, Shakuntala

    Pediatrics in review

    2018  Volume 39, Issue 5, Page(s) 265–266

    MeSH term(s) Biomarkers/cerebrospinal fluid ; Carbohydrate Metabolism, Inborn Errors/cerebrospinal fluid ; Carbohydrate Metabolism, Inborn Errors/complications ; Carbohydrate Metabolism, Inborn Errors/diagnosis ; Glucose/cerebrospinal fluid ; Humans ; Infant, Newborn ; Male ; Monosaccharide Transport Proteins/cerebrospinal fluid ; Monosaccharide Transport Proteins/deficiency ; Seizures/etiology
    Chemical Substances Biomarkers ; Monosaccharide Transport Proteins ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2018-04-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 774515-1
    ISSN 1526-3347 ; 0191-9601
    ISSN (online) 1526-3347
    ISSN 0191-9601
    DOI 10.1542/pir.2017-0154
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Vascular endothelial growth factor levels and bronchopulmonary dysplasia in preterm infants.

    Mariduena, Joseph / Ramagopal, Maya / Hiatt, Mark / Chandra, Shakuntala / Laumbach, Robert / Hegyi, Thomas

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2020  Volume 35, Issue 8, Page(s) 1517–1522

    Abstract: Background: Vascular endothelial growth factor (VEGF) and its receptors (VEGFRs) regulate both vasculogenesis, the development of blood vessels from precursor cells, and angiogenesis, the formation of blood vessels from preexisting vessels. In the fetal ...

    Abstract Background: Vascular endothelial growth factor (VEGF) and its receptors (VEGFRs) regulate both vasculogenesis, the development of blood vessels from precursor cells, and angiogenesis, the formation of blood vessels from preexisting vessels. In the fetal lung, high-affinity receptors for VEGF are expressed mainly in alveolar epithelial cells and myocytes, suggesting a paracrine role for VEGF in modulating activities in adjacent vascular endothelium. Previous studies have shown that vascular growth is impaired in bronchopulmonary dysplasia (BPD).
    Objective: The goal of this study was to examine tracheal (T-VEGF) and gastric (G-VEGF) levels in premature infants in the first and third day of life and examine if these levels were associated with the development of BPD.
    Design/methods: Tracheal aspirates from intubated infants and gastric samples from others were obtained on postnatal days 1 (D1) and 3 (D3) from 43 preterm infants (<2000 g birth weight, ≤34 wks gestation). VEGF was quantified by a VEGF Elisa Kit. Demographic, clinical, and pulmonary outcome data were collected including information on respiratory support (oxygenation index (OI) and ventilatory index (VI)) and on the development of BPD, determined at 36 weeks PMA using NICHD criteria.
    Results: The mean birth weight was 1060 ± 379 g and gestational age 27.5 ± 2.8 wks. BPD was diagnosed in 26 infants who were less mature than the 17 controls without BPD. Day 1 and day 3T-VEGF concentrations did not correlate, but day 3 levels correlated with gestational age (
    Conclusions: BPD may be associated with low-serum VEGF levels during the first week of life. This finding is likely related to decreased expression in the lungs of the less mature infants, who are at the highest risk for BPD.
    MeSH term(s) Bronchopulmonary Dysplasia ; Female ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Infant, Premature/metabolism ; Pregnancy ; Vascular Endothelial Growth Factor A ; Vascular Endothelial Growth Factors
    Chemical Substances VEGFA protein, human ; Vascular Endothelial Growth Factor A ; Vascular Endothelial Growth Factors
    Language English
    Publishing date 2020-05-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2020.1760826
    Database MEDical Literature Analysis and Retrieval System OnLINE

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