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  1. Article ; Online: Images Combined With Surgical Procedures and Pathological Identification to Distinguish a Reactive Histiocytosis With Organized Hematoma From a Malignant Peripheral Nerve Sheath Tumor.

    Chang, Chun-Jen / Chen, Chun-Chung / Cho, DER-Yang / Bau, DA-Tian / Chen, Chao-Hsuan

    In vivo (Athens, Greece)

    2023  Volume 37, Issue 3, Page(s) 1365–1372

    Abstract: Background/aim: Malignant peripheral nerve sheath tumors (MPNST) are rare soft tissue malignant tumors. To the best of our knowledge, there have been no previous reports of benign reactive histiocytosis with hematoma that mimics MPNST on medical images.! ...

    Abstract Background/aim: Malignant peripheral nerve sheath tumors (MPNST) are rare soft tissue malignant tumors. To the best of our knowledge, there have been no previous reports of benign reactive histiocytosis with hematoma that mimics MPNST on medical images.
    Case report: A 57-year-old female with past history of hypertension came to our clinic due to low back pain with radiculopathy which was diagnosed with a tumor arising from L2 neuroforamen with L2 pedical erosion. Initial tentative diagnosis on the images was MPNST. However, after surgical resection, the pathologic report revealed no evidence of malignancy but only an organized hematoma with reactive histiocytosis.
    Conclusion: Images cannot provide enough diagnostic evidence for distinguishing a reactive histiocytosis from MPNST. Proper surgical procedures and expert pathological identification can correct the mistaking of the ambiguous identification as MPNST. Images can only provide precise and personalized medication accompanied by proper surgical procedures and expert pathological identification.
    MeSH term(s) Female ; Humans ; Middle Aged ; Nerve Sheath Neoplasms/diagnosis ; Nerve Sheath Neoplasms/surgery ; Nerve Sheath Neoplasms/pathology ; Neurofibrosarcoma/complications ; Histiocytosis/complications
    Language English
    Publishing date 2023-04-27
    Publishing country Greece
    Document type Case Reports ; Journal Article
    ZDB-ID 807031-3
    ISSN 1791-7549 ; 0258-851X
    ISSN (online) 1791-7549
    ISSN 0258-851X
    DOI 10.21873/invivo.13218
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    Zs.A 2288: Show issues Location:
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  2. Article ; Online: Surgical interventions for Bertolotti's syndrome: case report and review of unsatisfactory cases in the literature.

    Chang, Chun-Jen / Chiu, You-Pen / Ji, Hui-Ru / Chu, Chang-Hung / Chiu, Cheng-Di

    BMC surgery

    2022  Volume 22, Issue 1, Page(s) 36

    Abstract: Background: Bertolotti's syndrome (BS) is characterized by the enlargement of transverse processes in caudal lumbar segments, causing chronic and persistent low back pain or sciatica. The present study aimed to describe our surgical technique for BS ... ...

    Abstract Background: Bertolotti's syndrome (BS) is characterized by the enlargement of transverse processes in caudal lumbar segments, causing chronic and persistent low back pain or sciatica. The present study aimed to describe our surgical technique for BS treatment and to review existing literature describing unsatisfactory outcomes.
    Case presentation: We report a patient who complained of lower back pain and soreness that intermittently radiated to his left leg for longer than 10 years. Based on an examination of his symptoms and signs, including imaging and electrical physiology assessments, in addition to the report of temporary pain relief after a local steroid injection to a diagnostic trigger site (articulation between the transverse process and the sacral ala or iliac crest), the patient was diagnosed with BS. The applied surgical techniques included minimally invasive, three-dimensional C-arm guidance, a tubing approach, and microscopic and bone cavitron ultrasonic surgical aspirator-assisted operations. After surgery, improvements were reported on the visual analog scale (from 8 to 2 points on a 10-point scale) and the straight leg raising test for the left leg (20° to 90°) within 3 days. The patient gained an ordinary life and returned to work within one week of surgery, with no observed postoperative complications.
    Conclusions: Minimally invasive tubular microscopic decompression and disarticulation is an effective method for treating BS. However, to achieve a successful outcome, it is recommended to use physician-proficient techniques that are in line with the patient's diagnosis.
    MeSH term(s) Humans ; Leg ; Low Back Pain/etiology ; Low Back Pain/surgery ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/surgery ; Lumbosacral Region ; Treatment Outcome
    Language English
    Publishing date 2022-02-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2050442-1
    ISSN 1471-2482 ; 1471-2482
    ISSN (online) 1471-2482
    ISSN 1471-2482
    DOI 10.1186/s12893-022-01498-y
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  3. Article ; Online: The clinical and biochemical characteristics associated with insulin resistance in non-obese young women

    Wang, Ching-Chiung / Chang, Chun-Jen / Hsu, Ming-I

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

    2016  Volume 32, Issue 9, Page(s) 767–771

    Abstract: Aim: The aim of this study was to investigate the biomarkers of insulin resistance in non-obese women.: Design: This was a retrospective study.: Patients: A total 229 non-obese women (Body mass index: BMI < 25) were evaluated.: Main outcome ... ...

    Abstract Aim: The aim of this study was to investigate the biomarkers of insulin resistance in non-obese women.
    Design: This was a retrospective study.
    Patients: A total 229 non-obese women (Body mass index: BMI < 25) were evaluated.
    Main outcome measure(s): Serum levels of various androgens, cardiovascular risk and metabolic components.
    Results: There were no significant differences in the prevalence of polycystic ovary syndrome (PCOS), hyperprolactinemia, or premature ovarian failure (POF) between the non-obese women with and without insulin resistance. Non-obese women with insulin had significantly higher serum thyroid stimulation hormone (TSH) levels and resistin and lower serum adiponectin levels than non-obese women without insulin resistance; however, the inflammatory biomarkers and serum androgen levels did not differ between the two groups. Furthermore, using step-wise multivariate regression analysis applied by the risk factors listed above, TSH was the only predictive factor for insulin resistance in non-obese reproductive-aged women.
    Conclusions: Thyroid function should play an important role in developing insulin resistance for non-obese women. Serum androgens and inflammation might not contribute to insulin resistance in these women.
    MeSH term(s) Adult ; Androgens/blood ; Body Mass Index ; Female ; Humans ; Hyperprolactinemia/blood ; Hyperprolactinemia/epidemiology ; Insulin Resistance/physiology ; Polycystic Ovary Syndrome/blood ; Polycystic Ovary Syndrome/epidemiology ; Primary Ovarian Insufficiency/blood ; Primary Ovarian Insufficiency/epidemiology ; Retrospective Studies ; Taiwan/epidemiology ; Thyrotropin/blood ; Young Adult
    Chemical Substances Androgens ; Thyrotropin (9002-71-5)
    Language English
    Publishing date 2016-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 639237-4
    ISSN 1473-0766 ; 0951-3590
    ISSN (online) 1473-0766
    ISSN 0951-3590
    DOI 10.3109/09513590.2016.1163671
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    Zs.MO 608: Show issues

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  4. Article ; Online: Pheochromocytoma presenting as hyperglycemic hyperosmolar syndrome and unusual fever.

    Lee, I-Shuan / Lee, Ting-Wei / Chang, Chun-Jen / Chien, Yu-Mei / Lee, Ting-I

    Internal and emergency medicine

    2015  Volume 10, Issue 6, Page(s) 753–755

    MeSH term(s) Adrenal Gland Neoplasms/complications ; Aged ; Body Mass Index ; Female ; Fever/etiology ; Humans ; Hyperglycemic Hyperosmolar Nonketotic Coma/diagnosis ; Hyperglycemic Hyperosmolar Nonketotic Coma/etiology ; Pheochromocytoma/diagnosis ; Pheochromocytoma/diagnostic imaging
    Language English
    Publishing date 2015-09
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-015-1217-5
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  5. Article ; Online: Correlates of Nocturia and Relationships of Nocturia With Sleep Quality and Glycemic Control in Women With Type 2 Diabetes.

    Chang, Chun-Jen / Pei, Dee / Wu, Chien-Chih / Palmer, Mary H / Su, Ching-Chieh / Kuo, Shu-Fen / Liao, Yuan-Mei

    Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing

    2017  Volume 49, Issue 4, Page(s) 400–410

    Abstract: Purposes: To explore correlates of nocturia, compare sleep quality and glycemic control for women with and without nocturia, and examine relationships of nocturia with sleep quality and glycemic control in women with diabetes.: Design: This study was ...

    Abstract Purposes: To explore correlates of nocturia, compare sleep quality and glycemic control for women with and without nocturia, and examine relationships of nocturia with sleep quality and glycemic control in women with diabetes.
    Design: This study was a cross-sectional, correlational study with data collected from 275 women with type 2 diabetes.
    Methods: Data were collected using a structured questionnaire. Multivariate logistic regression analyses were used to identify correlates. Chi-squared tests were used to identify candidate variables for the first logistic regression model. A one-way analysis of variance was used to compare sleep quality and glycemic control for women with and those without nocturia. Pearson correlations were used to examine the relationships of nocturia with sleep quality and glycemic control.
    Findings: Of the 275 participants, 124 (45.1%) had experienced nocturia (at least two voids per night). Waist circumference, parity, time since diagnosis of diabetes, sleep quality, and increased daytime urinary frequency were correlated with nocturia after adjusting for age. Compared to women without nocturia, women who had nocturia reported poorer sleep quality. A significant correlation was found between the number of nocturnal episodes and sleep quality.
    Conclusions: Nocturia and poor sleep are common among women with diabetes. The multifactorial nature of nocturia supports the delivered management and treatments being targeted to underlying etiologies in order to optimize women's symptom management. Interventions aimed at modifiable correlates may include maintaining a normal body weight and regular physical exercise for maintaining a normal waist circumference, and decreasing caffeine consumption, implementing feasible modifications in sleeping environments and maintaining sleep hygiene to improve sleep quality.
    Clinical relevance: Healthcare professionals should screen for nocturia and poor sleep and offer appropriate nonpharmacological lifestyle management, behavioral interventions, or pharmacotherapy for women with diabetes.
    MeSH term(s) Adult ; Aged ; Blood Glucose/metabolism ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/physiopathology ; Female ; Humans ; Middle Aged ; Nocturia/epidemiology ; Risk Factors ; Sleep/physiology ; Surveys and Questionnaires ; Young Adult
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2017-05-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2008214-9
    ISSN 1547-5069 ; 1527-6546
    ISSN (online) 1547-5069
    ISSN 1527-6546
    DOI 10.1111/jnu.12302
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    Zs.B 2842: Show issues Location:
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  6. Article ; Online: Psychometric testing of a Mandarin Chinese Version of the Clinically Useful Depression Outcome Scale for patients diagnosed with type 2 diabetes mellitus.

    Hsu, Lan-Fang / Kao, Ching-Chiu / Wang, Mei-Yeh / Chang, Chun-Jen / Tsai, Pei-Shan

    International journal of nursing studies

    2014  Volume 51, Issue 12, Page(s) 1595–1604

    Abstract: Background: The Clinically Useful Depression Outcome Scale (CUDOS) is a self-report instrument that assesses symptoms and the severity of depression, but its psychometric properties in patients with type 2 diabetes mellitus in Chinese-Speaking ... ...

    Abstract Background: The Clinically Useful Depression Outcome Scale (CUDOS) is a self-report instrument that assesses symptoms and the severity of depression, but its psychometric properties in patients with type 2 diabetes mellitus in Chinese-Speaking populations are unknown.
    Objectives: To examine the psychometric properties of the Mandarin Chinese version of the CUDOS (CUDOS-Chinese).
    Design: A methodological research design.
    Setting: Endocrinology and metabolism outpatient clinics at 2 university-affiliated hospitals in northern Taiwan.
    Participants: Two-hundred and fourteen type 2 diabetic patients with the mean age of 62.6 years were enrolled, and two-hundred and twelve of them completed the study.
    Methods: Internal consistency, test-retest reliability, concurrent, and contrasted-groups validity were assessed. A receiver operating characteristic curve analysis was performed to assess sensitivity and specificity. Construct validity by means of confirmatory factor analysis was conducted.
    Results: Internal consistency (Cronbach α of total scale and four subscales=0.93, 0.80, 0.66, 0.80, and 0.83, respectively), test-retest reliability (intra-class correlation coefficients of total scale and four subscales=0.92, 0.89, 0.94, 0.89, and 0.91, respectively), and strong correlations with the Beck Depression Inventory-II (r=0.87) suggested good reliability and validity. The confirmatory factor analysis supported a four-factor model. A cut-off score of 19/20 yielded 77.8% sensitivity and 75.6% specificity.
    Conclusions: The CUDOS-Chinese demonstrated satisfactory validity and reliability for detecting depression in type 2 diabetic patients in Taiwan.
    MeSH term(s) Aged ; Depressive Disorder/complications ; Depressive Disorder/diagnosis ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/psychology ; Female ; Humans ; Male ; Middle Aged ; Psychometrics ; Taiwan
    Language English
    Publishing date 2014-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80148-3
    ISSN 1873-491X ; 0020-7489
    ISSN (online) 1873-491X
    ISSN 0020-7489
    DOI 10.1016/j.ijnurstu.2014.05.004
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  7. Article ; Online: Potential of vitamin D in treating diabetic cardiomyopathy.

    Lee, Ting-Wei / Lee, Ting-I / Chang, Chun-Jen / Lien, Gi-Shih / Kao, Yu-Hsun / Chao, Tze-Fan / Chen, Yi-Jen

    Nutrition research (New York, N.Y.)

    2015  Volume 35, Issue 4, Page(s) 269–279

    Abstract: Cardiovascular disease is the leading cause of morbidity and mortality in patients with diabetes mellitus (DM), and patients with DM frequently develop diabetic cardiomyopathy. Currently, effective treatments for diabetic cardiomyopathy are limited. ... ...

    Abstract Cardiovascular disease is the leading cause of morbidity and mortality in patients with diabetes mellitus (DM), and patients with DM frequently develop diabetic cardiomyopathy. Currently, effective treatments for diabetic cardiomyopathy are limited. Vitamin D exerts pleiotropic effects on the cardiovascular system and is associated with DM. The purpose of this review was to evaluate published research on vitamin D in diabetic cardiomyopathy by searching PubMed databases. Herein, we reviewed vitamin D metabolism; evaluated the molecular, cellular, and neuroendocrine effects in native and bioactive vitamin D; and evaluated the role of vitamin D in treating cardiovascular disease and DM. Some evidence suggests that vitamin D may improve cardiovascular outcomes in diabetes through anti-inflammatory, antioxidative, antihypertrophic, antifibrotic, and antiatherosclerotic activities and by regulating advanced glycation end-product signaling, the renin-angiotensin system, and cardiac metabolism. This clinical and laboratory evidence suggests that vitamin D may be a potential agent in treating diabetic cardiomyopathy. However, using vitamin D entails possible adverse risks of hypercalcemia, hyperphosphatemia, and vascular calcifications. Therefore, future studies should be conducted that clarify the potential benefits of vitamin D through large-scale randomized clinical trials in well-defined groups of diabetic patients.
    MeSH term(s) Animals ; Diabetic Cardiomyopathies/drug therapy ; Disease Models, Animal ; Humans ; Randomized Controlled Trials as Topic ; Renin-Angiotensin System ; Vitamin D/therapeutic use ; Vitamins/therapeutic use
    Chemical Substances Vitamins ; Vitamin D (1406-16-2)
    Language English
    Publishing date 2015-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 582432-1
    ISSN 1879-0739 ; 0271-5317
    ISSN (online) 1879-0739
    ISSN 0271-5317
    DOI 10.1016/j.nutres.2015.02.005
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    Zs.A 1686: Show issues Location:
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  8. Article ; Online: Pheochromocytoma mimicking both acute coronary syndrome and sepsis: a case report.

    Lee, Ting-Wei / Lin, Ke-Hsun / Chang, Chun-Jen / Lew, Wei-Han / Lee, Ting-I

    Medical principles and practice : international journal of the Kuwait University, Health Science Centre

    2012  Volume 22, Issue 4, Page(s) 405–407

    Abstract: Objective: To present an atypical manifestation in a patient with pheochromocytoma.: Clinical presentation and intervention: A 48-year-old man presented with chest pain, fever and leukocytosis. Elevated cardiac biomarkers and diffuse ST-T ... ...

    Abstract Objective: To present an atypical manifestation in a patient with pheochromocytoma.
    Clinical presentation and intervention: A 48-year-old man presented with chest pain, fever and leukocytosis. Elevated cardiac biomarkers and diffuse ST-T abnormalities on electrocardiography suggested myocardial infarction. However, coronary angiography showed normal coronary arteries. Abdominal computed tomography revealed a left adrenal tumor of 6.7 × 6.8 cm. Paroxysmal fluctuation of blood pressure raised the suspicion of pheochromocytoma, which was further supported by elevated urine catecholamine levels. He underwent left adrenalectomy and pathological findings confirmed the diagnosis.
    Conclusion: Pheochromocytoma should be considered as part of the differential diagnosis in a patient with symptoms suggestive of both acute coronary syndrome and sepsis.
    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Adrenal Gland Neoplasms/diagnosis ; Adrenal Gland Neoplasms/surgery ; Adrenalectomy ; C-Reactive Protein/analysis ; Catecholamines/urine ; Chest Pain/etiology ; Coronary Angiography ; Diagnosis, Differential ; Electrocardiography ; Fever/etiology ; Humans ; Leukocytosis/etiology ; Male ; Middle Aged ; Pheochromocytoma/diagnosis ; Pheochromocytoma/surgery ; Sepsis/diagnosis ; Troponin I/blood
    Chemical Substances Catecholamines ; Troponin I ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2012-10-27
    Publishing country Switzerland
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645108-1
    ISSN 1423-0151 ; 1011-7571
    ISSN (online) 1423-0151
    ISSN 1011-7571
    DOI 10.1159/000343578
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  9. Article ; Online: Calcitriol modulates receptor for advanced glycation end products (RAGE) in diabetic hearts.

    Lee, Ting-Wei / Kao, Yu-Hsun / Lee, Ting-I / Chang, Chun-Jen / Lien, Gi-Shih / Chen, Yi-Jen

    International journal of cardiology

    2014  Volume 173, Issue 2, Page(s) 236–241

    Abstract: Background: Receptor for advanced glycation end products (RAGE) signaling pathway plays a vital role in diabetic cardiovascular complications. Calcitriol has been shown to exert various beneficial cardiovascular effects. The purpose of this study is to ... ...

    Abstract Background: Receptor for advanced glycation end products (RAGE) signaling pathway plays a vital role in diabetic cardiovascular complications. Calcitriol has been shown to exert various beneficial cardiovascular effects. The purpose of this study is to determine whether calcitriol can modulate RAGE expression, and study the potential mechanisms in diabetic hearts.
    Methods: Streptozotocin (65 mg/kg, intraperitoneal injection once) induced diabetic rats were treated with or without subcutaneous injections of calcitriol at a dose of 150 ng/kg/day for 4 weeks. Western blot was used to evaluate protein expressions of myocardial RAGE, TNF-α, p65 subunit of NF-κB (p65), α subunit of inhibitor of κB (IκBα), subunits of NADPH oxidase (NOX4 and p22(phox)), angiotensin II type 1 receptor (AT1R), TGF-β1, TGF-β receptor I, total and phosphorylated SMAD2/3 and ERK, matrix metalloproteinases 2 (MMP2), tissue inhibitors of metalloproteinases 2 (TIMP2) and procollagen I.
    Results: As compared to control, diabetic rats had increased expressions of cardiac RAGE, TNF-α, p22(phox), AT1R, and TGF-β1, which were significantly attenuated in the diabetic rats treated with calcitriol. Calcitriol-treated diabetic hearts also had lesser expressions of p-SMAD2/3 and p-ERK signaling than those of diabetic hearts. Moreover, diabetic hearts had increased expressions of MMP2 and procollagen I and decreased TIMP2. However, calcitriol reverted the diabetic effects in procollagen I but not in MMP2 or TIMP2.
    Conclusions: Calcitriol decreased diabetic effects on RAGE and fibrosis, which may be caused by its modulation on AT1R and the anti-inflammatory and antioxidative potentials. Therefore, calcitriol may attenuate diabetic cardiomyopathy.
    MeSH term(s) Animals ; Antioxidants/pharmacology ; Calcitriol/pharmacology ; Collagen Type I/metabolism ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Experimental/metabolism ; Diabetic Cardiomyopathies/drug therapy ; Diabetic Cardiomyopathies/metabolism ; Male ; Matrix Metalloproteinase 2/metabolism ; NADPH Oxidases/metabolism ; Oxidative Stress/drug effects ; Rats, Inbred WKY ; Receptor for Advanced Glycation End Products ; Receptors, Angiotensin/metabolism ; Receptors, Immunologic/metabolism ; Receptors, Transforming Growth Factor beta/metabolism ; Signal Transduction/drug effects ; Tissue Inhibitor of Metalloproteinase-2/metabolism ; Treatment Outcome ; Tumor Necrosis Factor-alpha/metabolism ; Vitamins/pharmacology
    Chemical Substances Agtrap protein, rat ; Antioxidants ; Collagen Type I ; Receptor for Advanced Glycation End Products ; Receptors, Angiotensin ; Receptors, Immunologic ; Receptors, Transforming Growth Factor beta ; Tumor Necrosis Factor-alpha ; Vitamins ; Tissue Inhibitor of Metalloproteinase-2 (127497-59-0) ; NADPH Oxidases (EC 1.6.3.-) ; Cyba protein, rat (EC 1.6.3.1) ; Matrix Metalloproteinase 2 (EC 3.4.24.24) ; Mmp2 protein, rat (EC 3.4.24.24) ; Calcitriol (FXC9231JVH)
    Language English
    Publishing date 2014-02-28
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2014.02.041
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  10. Article: Pheochromocytoma Mimicking both Acute Coronary Syndrome and Sepsis: A Case Report

    Lee, Ting-Wei / Lin, Ke-Hsun / Chang, Chun-Jen / Lew, Wei-Han / Lee, Ting-I

    Medical Principles and Practice

    2012  Volume 22, Issue 4, Page(s) 405–407

    Abstract: Objective: To present an atypical manifestation in a patient with pheochromocytoma. Clinical Presentation and Intervention: A 48-year-old man presented with chest pain, fever and leukocytosis. Elevated cardiac biomarkers and diffuse ST-T abnormalities on ...

    Institution Division of Endocrinology and Metabolism, Department of Internal Medicine, and Department of Urology, Wan Fang Hospital, Taipei Medical University, and Department of General Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Abstract Objective: To present an atypical manifestation in a patient with pheochromocytoma. Clinical Presentation and Intervention: A 48-year-old man presented with chest pain, fever and leukocytosis. Elevated cardiac biomarkers and diffuse ST-T abnormalities on electrocardiography suggested myocardial infarction. However, coronary angiography showed normal coronary arteries. Abdominal computed tomography revealed a left adrenal tumor of 6.7 × 6.8 cm. Paroxysmal fluctuation of blood pressure raised the suspicion of pheochromocytoma, which was further supported by elevated urine catecholamine levels. He underwent left adrenalectomy and pathological findings confirmed the diagnosis. Conclusion: Pheochromocytoma should be considered as part of the differential diagnosis in a patient with symptoms suggestive of both acute coronary syndrome and sepsis.
    Keywords Catecholamine ; Pheochromocytoma ; Coronary artery disease ; Sepsis
    Language English
    Publishing date 2012-10-27
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    ZDB-ID 645108-1
    ISSN 1423-0151 ; 1011-7571
    ISSN (online) 1423-0151
    ISSN 1011-7571
    DOI 10.1159/000343578
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