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Article ; Online: Long noncoding RNA PCAT-1 promoted ovarian cancer cell proliferation and invasion by suppressing KLF6.

Liu, H-P / Lv, D / Wang, J-Y / Zhang, Y / Chang, J-F / Liu, Z-T / Tang, N

European review for medical and pharmacological sciences

2020 Volume 24, Issue 14, Page(s) 7566

Abstract: Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Long noncoding RNA PCAT-1 promoted ovarian cancer cell proliferation and invasion by ... ...

Abstract	Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Long noncoding RNA PCAT-1 promoted ovarian cancer cell proliferation and invasion by suppressing KLF6, by H.-P. Liu, D. Lv, J.-Y. Wang, Y. Zhang, J.-F. Chang, Z.-T. Liu, N. Tang, published in Eur Rev Med Pharmacol Sci 2019; 23 (11): 4650-4655-DOI: 10.26355/eurrev_201906_18044-PMID: 31210290" has been withdrawn. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/18044.
Language	English
Publishing date	2020-08-19
Publishing country	Italy
Document type	Journal Article ; Retraction of Publication
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
DOI	10.26355/eurrev_202007_22228
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Article ; Online: Long noncoding RNA PCAT-1 promoted ovarian cancer cell proliferation and invasion by suppressing KLF6.

Liu, H-P / Lv, D / Wang, J-Y / Zhang, Y / Chang, J-F / Liu, Z-T / Tang, N

publication RETRACTED

European review for medical and pharmacological sciences

2019 Volume 23, Issue 11, Page(s) 4650–4655

Abstract: Objective: Recently, the role of long noncoding RNAs (lncRNAs) in tumor progression has caught attention in numerous researchers. In our investigation, lncRNA PCAT-1 was studied to identify how it functioned in the progression of ovarian cancer.: ... ...

Abstract	Objective: Recently, the role of long noncoding RNAs (lncRNAs) in tumor progression has caught attention in numerous researchers. In our investigation, lncRNA PCAT-1 was studied to identify how it functioned in the progression of ovarian cancer. Patients and methods: LncRNA PCAT-1 expression was detected by quantitative Real-time polymerase chain reaction (qRT-PCR) in both ovarian cancer cells and tissue samples. Furthermore, to identify the function of PCAT-1 in ovarian cancer, cell proliferation, transwell assay and Matrigel assay were conducted. In addition, by performing qRT-PCR and Western blot assay, the underlying mechanism was explored. Results: PCAT-1 expression was remarkably higher in ovarian cancer samples when compared with that in corresponding ones. Moreover, cell proliferation, migration and invasion were inhibited after PCAT-1 was knocked down in ovarian cancer cells. Moreover, the mRNA and protein expression of KLF6 (Krüppel-like factor 6) was upregulated after PCAT-1 was knocked down. Furthermore, the KLF6 expression level was negatively related to the PCAT-1 expression level in ovarian cancer samples. Conclusions: We showed that PCAT-1 promotes the progression of ovarian cancer through enhancing cell metastasis and proliferation via suppressing KLF6, which might be a novel therapeutic strategy in ovarian cancer.
Language	English
Publishing date	2019-06-18
Publishing country	Italy
Document type	Journal Article ; Retracted Publication
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
DOI	10.26355/eurrev_201906_18044
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Article: Validation of selective attention and memory measures as early markers for Alzheimer's disease.

Tse, C S / Lam, L C W / Balota, D A / Leung, G T Y / Hau, K T / Chang, J F

Hong Kong medical journal = Xianggang yi xue za zhi

2016 Volume 22 Suppl 2, Page(s) S37–9

MeSH term(s)	Activities of Daily Living ; Aged ; Aged, 80 and over ; Alzheimer Disease/diagnosis ; Alzheimer Disease/psychology ; Attention ; Cognition ; Hong Kong ; Humans ; Memory ; Psychiatric Status Rating Scales ; Reproducibility of Results ; Severity of Illness Index
Language	English
Publishing date	2016-02
Publishing country	China
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Validation Studies
ZDB-ID	1239255-8
ISSN	1024-2708
ISSN	1024-2708
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Article ; Online: Scintillator-based fast ion loss measurements in the EAST.

Chang, J F / Isobe, M / Ogawa, K / Huang, J / Wu, C R / Xu, Z / Jin, Z / Lin, S Y / Hu, L Q

The Review of scientific instruments

2016 Volume 87, Issue 11, Page(s) 11E728

Abstract: A new scintillator-based fast ion loss detector (FILD) has been installed on Experimental Advanced Superconducting Tokamak (EAST) to investigate the fast ion loss behavior in high performance plasma with neutral beam injection (NBI) and ion cyclotron ... ...

Abstract	A new scintillator-based fast ion loss detector (FILD) has been installed on Experimental Advanced Superconducting Tokamak (EAST) to investigate the fast ion loss behavior in high performance plasma with neutral beam injection (NBI) and ion cyclotron resonance heating (ICRH). A two dimensional 40 mm × 40 mm scintillator-coated (ZnS:Ag) stainless plate is mounted in the front of the detector, capturing the escaping fast ions. Photons from the scintillator plate are imaged with a Phantom V2010 CCD camera. The lost fast ions can be measured with the pitch angle from 60° to 120° and the gyroradius from 10 mm to 180 mm. This paper will describe the details of FILD diagnostic on EAST and describe preliminary measurements during NBI and ICRH heating.
Language	English
Publishing date	2016-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	209865-9
ISSN	1089-7623 ; 0034-6748
ISSN (online)	1089-7623
ISSN	0034-6748
DOI	10.1063/1.4962245
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Article: Collection of pheromone from atmosphere surrounding boll weevils,Anthonomus grandis.

Chang, J F / Benedict, J H / Payne, T L / Camp, B J / Vinson, S B

Journal of chemical ecology

2013 Volume 15, Issue 2, Page(s) 767–777

Abstract: An effluvial method was developed to collect the pheromone, grandlure from actively calling male boll weevils,Anthonomus grandis Boheman. The adsorbant, Porapak Q (ethylvinylbenzene-divinylbenzene), was utilized to trap and concentrate the pheromone. ... ...

Abstract	An effluvial method was developed to collect the pheromone, grandlure from actively calling male boll weevils,Anthonomus grandis Boheman. The adsorbant, Porapak Q (ethylvinylbenzene-divinylbenzene), was utilized to trap and concentrate the pheromone. Captured pheromone was desorbed from columns packed with Porapak Q by elution withn-pentane and quantified by capillary column gas-liquid chromatography. In recovery studies with known amounts of synthetic grandlure, we found that the amount of each pheromone component collected was a function of collection duration, elution volume, and initial concentration. This effluvial method was capable of recovering as much as 94.9% of a known quantity (80 μg) of grandlure. The chromatograms were free of extraneous peaks. In studies of insect-produced pheromone, the effluvial method was used to collect pheromone from the air space surrounding male boll weevils as they fed on flower buds from CAMD-E cotton. The quantity and quality of boll-weevil-produced pheromone was determined for days 6, 8, 10, 11, 12, 13, and 14 of boll weevil adulthood. The maximum quantity of natural pheromone was produced on day 13 (4.2 μg/weevil) with a pheromone component ratio of 2.41∶2.29∶0.95∶1 for components I, II, III, and IV, respectively. The effluvial method described in this report is an efficient method to collect and quantify boll weevil pheromone from the atmosphere surrounding actively calling insects. Other applications of this method are suggested.
Language	English
Publishing date	2013-11-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	800130-3
ISSN	1573-1561 ; 0098-0331
ISSN (online)	1573-1561
ISSN	0098-0331
DOI	10.1007/BF01014717
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Performance of fast-ion loss diagnostic on EAST.

Wu, C R / Huang, J / Chang, J F / Zhang, J / Zhou, R J / Xu, Z / Gao, W / Isobe, M / Ogawa, K / Lin, S Y / Hu, L Q / Li, J G

The Review of scientific instruments

2018 Volume 89, Issue 10, Page(s) 10I144

Abstract: The scintillator-based detector for fast-ion loss measurements has been installed on EAST. To obtain high temporal resolution for fast-ion loss diagnostics, fast photomultiplier tube systems have been developed which can supply the complementary ... ...

Abstract	The scintillator-based detector for fast-ion loss measurements has been installed on EAST. To obtain high temporal resolution for fast-ion loss diagnostics, fast photomultiplier tube systems have been developed which can supply the complementary measurements to the previous image system with good energy and pitch resolution by using a CCD camera. By applying the rotatable platform, the prompt losses of beam-ions can be measured in normal and reverse magnetic field. The thick-target bremsstrahlung occurring in the stainless steel shield with energetic electrons can produce X-rays, which will strike on the scintillator based detector. To understand this interference on fast-ion loss signals, the effects of energetic electrons on the scintillator-based detector are studied, including runaway electrons in the plasma ramping-up phase and fast electrons accelerated by the lower hybrid wave.
Language	English
Publishing date	2018-11-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	209865-9
ISSN	1089-7623 ; 0034-6748
ISSN (online)	1089-7623
ISSN	0034-6748
DOI	10.1063/1.5038782
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Article ; Online: Fast ion D-alpha measurements using a bandpass-filtered system on EAST.

Zhang, J / Huang, J / Chang, J F / Wu, C R / Heidbrink, W W / Salewski, M / Madsen, B / Zhu, Y B / von Hellermann, M G / Gao, W / Xu, Z / Wan, B

The Review of scientific instruments

2018 Volume 89, Issue 10, Page(s) 10D121

Abstract: Based on the charge exchange reaction between fast ions and a neutral beam, fast ion features can be inferred from the spectrum of Doppler-shifted Balmer-alpha light from energetic hydrogenic atoms. In order to study the interaction between instabilities ...

Abstract	Based on the charge exchange reaction between fast ions and a neutral beam, fast ion features can be inferred from the spectrum of Doppler-shifted Balmer-alpha light from energetic hydrogenic atoms. In order to study the interaction between instabilities and fast-ion transport, recently we extended the fast ion D-alpha (FIDA) measurements by using a combination of a bandpass filter and a photomultiplier tube (PMT) (f-FIDA). A bandpass filter selects the desired spectral band from 651 nm to 654 nm before detection by the PMT. Preliminary data from the EAST tokamak show that the active signals have been detected from reneutralized beam ions along the vertical and tangential viewing geometries. The details will be presented in this paper to primarily address the specifications and performance of f-FIDA hardware components and preliminary FIDA measurements.
Language	English
Publishing date	2018-11-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	209865-9
ISSN	1089-7623 ; 0034-6748
ISSN (online)	1089-7623
ISSN	0034-6748
DOI	10.1063/1.5038828
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Article ; Online: The utility of a non-verbal prospective memory measure as a sensitive marker for early-stage Alzheimer's disease in Hong Kong.

Tse, C S / Chang, J F / Fung, Ada W T / Lam, Linda C W / Hau, K T / Leung, Grace T Y / Balota, D A

International psychogeriatrics

2014 , Page(s) 1–12

Abstract: ABSTRACT Background: With the proportion of older adults in Hong Kong projected to double in size in the next 30 years, it is important to develop measures for detecting individuals in the earliest stage of Alzheimer's disease (AD, 0.5 in Clinical ... ...

Abstract	ABSTRACT Background: With the proportion of older adults in Hong Kong projected to double in size in the next 30 years, it is important to develop measures for detecting individuals in the earliest stage of Alzheimer's disease (AD, 0.5 in Clinical Dementia Rating, CDR). We tested the utility of a non-verbal prospective memory task (PM, ability to remember what one has to do when a specific event occurs in the future) as an early marker for AD in Hong Kong Chinese. Methods: A large community dwelling sample of older adults who are healthy controls (CDR 0, N = 125), in the earliest stage of AD (CDR 0.5, N = 125), or with mild AD (CDR 1, N = 30) participated in this study. Their reaction time/accuracy data were analyzed by mixed-factor analyses of variance to compare the performance of the three CDR groups. Logistic regression analyses were performed to test the discriminative power of these measures for CDR 0 versus 0.5 participants. Results: Prospective memory performance declined as a function of AD severity: CDR 0 > CDR 0.5 > CDR 1, suggesting the effects of early-stage AD and AD progression on PM. After partialling out the variance explained by psychometric measures (e.g., ADAS-Cog), reaction time/accuracy measures that reflected the PM still significantly discriminated between CDR 0 versus 0.5 participants in most of the cases. Conclusion: The effectiveness of PM measures in discriminating individuals in the earliest stage of AD from healthy older adults suggests that these measures should be further developed as tools for early-stage AD discrimination.
Language	English
Publishing date	2014-09-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1038825-4
ISSN	1741-203X ; 1041-6102
ISSN (online)	1741-203X
ISSN	1041-6102
DOI	10.1017/S1041610214002038
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Article ; Online: Effects of education on very mild dementia among Chinese people in Hong Kong: potential mediators in the Cantonese Mini-Mental State Examination tasks.

Tse, C S / Chang, J F / Leung, Grace T Y / Fung, Ada W T / Hau, K T / Chiu, Helen F K / Lam, Linda C W

Aging & mental health

2013 Volume 17, Issue 3, Page(s) 310–318

Abstract: Background: In Hong Kong, older Chinese adults generally have a low level of education. This study examined the effect of education on very mild Alzheimer's disease (AD), as quantified by Clinical Dementia Rating (CDR) scale (CDR 0.5 versus 0), in a ... ...

Abstract	Background: In Hong Kong, older Chinese adults generally have a low level of education. This study examined the effect of education on very mild Alzheimer's disease (AD), as quantified by Clinical Dementia Rating (CDR) scale (CDR 0.5 versus 0), in a Chinese community. The Cantonese version of the Mini-Mental State Examination (C-MMSE) was used to estimate cognitive abilities that were related to the level of education, and that in turn serve as protective factors for AD. Methods: A total of 788 community-dwelling older adults (383 CDR 0 and 405 CDR 0.5) were recruited in this cross-sectional study, which was derived from a population-based prevalence project. The participants' number of years of education and C-MMSE scores were used to predict their CDR scores using logistic regression and the mediation effects of C-MMSE scores were analyzed. Results: Consistent with previous studies, the chance of being rated as having very mild AD increased with age, but decreased with years of education, among the older adult community of Hong Kong. The effect of education on very mild dementia was weakened substantially when C-MMSE scores were included as mediating variables. Conclusions: The findings indicate that the protective effects of education on dementia were mediated by an enhancement of older adults' performance on some C-MMSE items, including attention and orientation to time and place.
MeSH term(s)	Adult ; Age Factors ; Aged ; Aged, 80 and over ; Asian Continental Ancestry Group/psychology ; Asian Continental Ancestry Group/statistics & numerical data ; Cognition Disorders/prevention & control ; Cross-Sectional Studies ; Dementia/diagnosis ; Dementia/epidemiology ; Dementia/psychology ; Disability Evaluation ; Educational Status ; Female ; Hong Kong/epidemiology ; Humans ; Male ; Mental Status Schedule/statistics & numerical data ; Neuropsychological Tests ; Population Surveillance ; Prevalence ; Psychiatric Status Rating Scales ; Residential Facilities ; Severity of Illness Index
Language	English
Publishing date	2013
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1474804-6
ISSN	1364-6915 ; 1360-7863
ISSN (online)	1364-6915
ISSN	1360-7863
DOI	10.1080/13607863.2012.743962
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Article ; Online: Filterscope diagnostic system on the Experimental Advanced Superconducting Tokamak (EAST).

Xu, Z / Wu, Z W / Gao, W / Chen, Y J / Wu, C R / Zhang, L / Huang, J / Chang, J F / Yao, X J / Zhang, P F / Jin, Z / Hou, Y M / Guo, H Y

The Review of scientific instruments

2016 Volume 87, Issue 11, Page(s) 11D429

Abstract: A filterscope diagnostic system has been mounted to observe the line emission and visible bremsstrahlung emission from plasma on the experimental advanced superconducting tokamak during the 2014 campaign. By this diagnostic system, multiple wavelengths ... ...

Abstract	A filterscope diagnostic system has been mounted to observe the line emission and visible bremsstrahlung emission from plasma on the experimental advanced superconducting tokamak during the 2014 campaign. By this diagnostic system, multiple wavelengths including D
Language	English
Publishing date	2016-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	209865-9
ISSN	1089-7623 ; 0034-6748
ISSN (online)	1089-7623
ISSN	0034-6748
DOI	10.1063/1.4961294
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