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  1. AU="Chang, Ling"
  2. AU="Engel, S"
  3. AU=Li Feng
  4. AU="Suarez, Eric S"
  5. AU="Pokhilenko, I"

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  1. Buch ; Dissertation / Habilitation: ANGPTL4 and PTPRK as Wnt negative regulators during early Xenopus development

    Chang, Ling-Shih / Niehrs, Christof

    2018  

    Körperschaft Universität Heidelberg
    Verfasserangabe presented by Master of Science Ling-Shih Chang ; referees: Prof. Dr. Christof Niehrs, Prof. Dr. Michael Boutros
    Sprache Englisch ; Deutsch
    Umfang ii, 125 Blätter, Illustrationen, Diagramme, 30 cm
    Erscheinungsort Heidelberg
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Dissertation, Ruperto Carola University Heidelberg, Germany, 2018
    Anmerkung Text Englisch, Zusammenfassung in deutscher und englischer Sprache
    HBZ-ID HT020994189
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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    Verfügbar in ZB MED Köln/Königswinter

    SignaturLeihstatusStandort
    2021 E 831 bestellbar zur Ausleihe Magazin

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  2. Artikel: The Correlation between Hofstede's Cultural Dimensions and COVID-19 Data in the Early Stage of the COVID-19 Pandemic Period.

    Chang, Ling-Hsing / Wu, Sheng

    Healthcare (Basel, Switzerland)

    2023  Band 11, Heft 16

    Abstract: COVID-19 (coronavirus disease 2019) has become the deadliest virus to affect the international community in recent history, with more than 760 million people infected and more than 6.87 million deaths as of March 2023; therefore, based on Hofstede's ... ...

    Abstract COVID-19 (coronavirus disease 2019) has become the deadliest virus to affect the international community in recent history, with more than 760 million people infected and more than 6.87 million deaths as of March 2023; therefore, based on Hofstede's national cultural theory, this study collected Hofstede's six national cultural dimensions on a global scale, namely, power distance (PDI), individualism/collectivism (IDV), masculinity/femininity (MAS), uncertainty avoidance (UAI), long-term/short-term orientation (LTO), and indulgence/restraint (IVR) scores, and COVID-19 data from the World Health Organization (WHO) from 22 February 2020 to 30 February 2021. Then, based on eight items of global COVID-19 data, this study analyzed the correlation between Hofstede's six dimensions and the COVID-19 data from six regions (Africa (AFRO), Europe (EURO), the Americas (AMRO), the Western Pacific (WPRO), South East Asia (SEARO), and the Eastern Mediterranean (EMRO)) divided by the WHO. This study found the following: (1) Hofstede's six cultural dimensions indeed have a significant correlation with the COVID-19 data of different WHO regions in different ways. (2) Except for IDV and UAI, PDI is a highly critical factor and has a significant correlation with the COVID-19 data from AFRO and EMRO. MAS also is an important factor and has a significant correlation with COVID-19 data from WPRO and SEARO. Meanwhile, LTO has a significant correlation with some COVID-19 data from the AMRO region, and IVR has a significant correlation with some COVID-19 data from the EURO region. Finally, the new insights from this study are worthy of further study by scholars, and they will be of great help to global governments and medical institutions in formulating policies to suppress infectious diseases in the future.
    Sprache Englisch
    Erscheinungsdatum 2023-08-10
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11162258
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: The Relationship between Discrepancies in Career Anchors of Information Technology Personnel and Career Satisfaction.

    Chang, Ling-Hsing / Wu, Sheng

    Behavioral sciences (Basel, Switzerland)

    2023  Band 13, Heft 9

    Abstract: The career anchors of information technology personnel (ITP) are critical factors influencing their career satisfaction (CS), and these factors are also influenced by national culture. Although a number of scholars have studied the internal CS of ... ...

    Abstract The career anchors of information technology personnel (ITP) are critical factors influencing their career satisfaction (CS), and these factors are also influenced by national culture. Although a number of scholars have studied the internal CS of employees, these scholars have not explained how to increase the CS of ITP from both individual and organizational perspectives and to further improve the success rate of IS projects. Thus, this study adopts the goal-achievement gap (discrepancy) theory to explore the gap between the "internal career desires (career wants, CW)" and "external career opportunities (career have, CH)" of ITP in two different cultural societies, namely mainland China and the United Arab Emirates, and whether the gap impacts their CS. The data in this study were collected from the Internet. A survey was posted on Internet discussion forums for full-time ITP participants within organizations in China and the United Arab Emirates; thus, the results of this study are possibly only generalizable to these two countries. Finally, the results of this study provide the following contributions: (1) There are 13 career anchors (technical competence, managerial competence, autonomy, organizational stability, challenge, lifestyle, identity, creativity, variety, service, entrepreneurship, geographic security, and learning motivation) of ITP in China, which can be divided into three categories, and these are totally different from the four categories identified by ITP in the United Arab Emirates. (2) The surface analysis approach (RSA) to test the curvilinear relationship between the CW, CH, and CS of ITP indeed can explain more than the linear SEM (structural equation modeling) test between the CW and CS, CH, and CS separately, both tests are in two different cultural societies, China and the United Arab Emirates.
    Sprache Englisch
    Erscheinungsdatum 2023-09-21
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2651997-5
    ISSN 2076-328X
    ISSN 2076-328X
    DOI 10.3390/bs13090785
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Associations of timing, level, and pattern of secondhand smoke exposure with early alcohol initiation: A cohort study.

    Chang, Ling-Yin / Chiang, Tung-Liang

    Drug and alcohol dependence

    2023  Band 252, Seite(n) 110988

    Abstract: Background: Few studies explored the longitudinal link between early-life secondhand smoke (SHS) exposure and later alcohol initiation despite its risk for child behavioral difficulties. We examined the associations of the timing, level, and pattern of ... ...

    Abstract Background: Few studies explored the longitudinal link between early-life secondhand smoke (SHS) exposure and later alcohol initiation despite its risk for child behavioral difficulties. We examined the associations of the timing, level, and pattern of SHS exposure from pregnancy to childhood with early alcohol initiation and evaluated the sex differences in these associations.
    Methods: Data were from 16,440 participants of the Taiwan Birth Cohort Study conducted when the children were aged 6 months, 18 months, 3 years, 5.5 years, 8 years, and 12 years. Group-based trajectory modeling was applied to identified patterns of SHS exposure. A series of multiple logistic regression were conducted to examine study hypotheses.
    Results: Exposure to prenatal SHS was associated with an increased risk of early alcohol initiation (adjusted odds ratio [aOR] = 1.17, 95% confidence interval [CI] = 1.06, 1.30). Compared with the adolescents with a persistent-low-exposure trajectory, those who exhibited prenatal-high-decreasing (aOR = 1.18, 95% CI = 1.04, 1.35) or persistent-high-exposure (aOR = 1.27, 95% CI = 1.12, 1.45) patterns exhibited increased risks of early alcohol initiation. Those with higher cumulative levels of SHS exposure also exhibited an increased risk of early alcohol initiation (aOR = 1.03, 95% CI = 1.01, 1.04). Sex differences were also observed.
    Conclusions: Varying timing, levels, and longitudinal patterns of SHS exposure during early life had differential effects on early alcohol initiation, with the effects differing by sex. Targeting SHS exposure while considering the nature of exposure and sex differences could help prevent and curb alcohol use in adolescents.
    Mesh-Begriff(e) Child ; Pregnancy ; Adolescent ; Humans ; Male ; Female ; Environmental Exposure/adverse effects ; Tobacco Smoke Pollution/adverse effects ; Cohort Studies ; Logistic Models ; Ethanol
    Chemische Substanzen Tobacco Smoke Pollution ; Ethanol (3K9958V90M)
    Sprache Englisch
    Erscheinungsdatum 2023-10-10
    Erscheinungsland Ireland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 519918-9
    ISSN 1879-0046 ; 0376-8716
    ISSN (online) 1879-0046
    ISSN 0376-8716
    DOI 10.1016/j.drugalcdep.2023.110988
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1310: Hefte anzeigen Standort:
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  5. Artikel ; Online: Cytokinin oxidase gene CKX5 is modulated in the immunity of Arabidopsis to Botrytis cinerea.

    Wang, Ruolin / Li, Beibei / Zhang, Jiang / Chang, Ling

    PloS one

    2024  Band 19, Heft 3, Seite(n) e0298260

    Abstract: In our previous work, cytokinin (CK) signaling and biosynthesis were found to be modulated during Arabidopsis defense against infection by the necrotrophic pathogen Botrytis cinerea. Notably, the expression level of CYTOKININ OXIDASE/DEHYDROGENASE 5 ( ... ...

    Abstract In our previous work, cytokinin (CK) signaling and biosynthesis were found to be modulated during Arabidopsis defense against infection by the necrotrophic pathogen Botrytis cinerea. Notably, the expression level of CYTOKININ OXIDASE/DEHYDROGENASE 5 (CKX5) was significantly induced in B. cinerea-infected leaves and later in distant B. cinerea-untreated leaves of the same plant. To confirm and determine how CKX5 is involved in the response to B. cinerea infection, transcript levels of CKX family genes were analyzed in B. cinerea-inoculated leaves, and only CKX5 was remarkably induced by B. cinerea infection. Furthermore, CKX5-overexpressing Arabidopsis plants were more resistant to B. cinerea than wild-type plants. Transcription factors (TFs) binding to the CKX5 promoter were then screened by yeast one-hybrid assays. Quantitative Real-Time Reverse Transcription PCR (qRT-PCR) analysis further showed that genes encoding TFs, including WRKY40, WRKY33, ERF6, AHL15, AHL17, ANAC003, TCP13 and ANAC019, were also strongly induced in infected leaves, similar to CKX5. Analysis of ERF6-overexpressing plants and ERF6-and AHL15-knockout mutants indicated that ERF6 and AHL15 are involved in plant immunity to B. cinerea. Furthermore, CKX5 upregulation by B. cinerea infection was affected when ERF6 or AHL15 levels were altered. Our work suggests that CKX5 levels are controlled by the plant defense system to defend against attack by the pathogen B. cinerea.
    Mesh-Begriff(e) Arabidopsis/metabolism ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Botrytis/physiology ; Oxidoreductases/metabolism ; Plant Diseases/genetics ; Gene Expression Regulation, Plant
    Chemische Substanzen Arabidopsis Proteins ; cytokinin oxidase (EC 1.5.99.12) ; Oxidoreductases (EC 1.-)
    Sprache Englisch
    Erscheinungsdatum 2024-03-13
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298260
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: The life experiences of living alone among Indonesia dwelling widowed women: A phenomenological study.

    Widhowati, Siwi Sri / Chen, Ching-Min / Chang, Ling-Hui

    Health care for women international

    2024  , Seite(n) 1–19

    Abstract: In this study, the researchers aimed to understand the life experience of older widowed women living alone. Employing a phenomenological approach, we interviewed 15 older women (age 62 to 95) living alone at homes in two villages in Central Java. Through ...

    Abstract In this study, the researchers aimed to understand the life experience of older widowed women living alone. Employing a phenomenological approach, we interviewed 15 older women (age 62 to 95) living alone at homes in two villages in Central Java. Through systematic text condensation procedure, we identified five themes: (1) negative feelings at times, (2) getting used to living alone, (3) needing help to support independent living, (4) coping toward negative feelings, (5) attachment to the original house. We depicted the struggles of older women living alone in their homes. Despite the coping strategies they have developed over time, older women needed help during hard times, especially when getting sick. Families and neighbors were the main resources to maintain their independent living. Improving the home environment to increase suitability for aging residents and providing a support system are the options that best fit the needs and values the older women believed.
    Sprache Englisch
    Erscheinungsdatum 2024-01-30
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 632677-8
    ISSN 1096-4665 ; 0739-9332
    ISSN (online) 1096-4665
    ISSN 0739-9332
    DOI 10.1080/07399332.2024.2306976
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  7. Artikel ; Online: Sustained Partial Response to Afatinib in a Patient With Lung Adenocarcinoma Harboring HER2

    Chang, Ling-Kai / Shih, Jin-Yuan

    JCO precision oncology

    2022  Band 4, Seite(n) 912–915

    Sprache Englisch
    Erscheinungsdatum 2022-01-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2473-4284
    ISSN (online) 2473-4284
    DOI 10.1200/PO.20.00114
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  8. Artikel ; Online: Family environment characteristics and sleep duration in children: Maternal mental health as a mediator.

    Chang, Ling-Yin / Chiang, Tung-Liang

    Social science & medicine (1982)

    2022  Band 314, Seite(n) 115450

    Abstract: Background: Family environment is a key factor affecting children's health. However, little is known about whether and how the family environment affects sleep duration in children. This study investigated the effects of both physical and social ... ...

    Abstract Background: Family environment is a key factor affecting children's health. However, little is known about whether and how the family environment affects sleep duration in children. This study investigated the effects of both physical and social characteristics of the family environment on sleep duration in children and determined whether these associations were mediated by maternal mental health.
    Methods: Data were obtained from the Taiwan Birth Cohort Study. A total of 19,400 children who completed 6-month, 18-month, 3-year, 5.5-year, and 8-year surveys were analyzed. The physical family environment characteristics were household crowding and housing quality. Family functioning was used as an indicator of family social environment. Multiple linear regression and path analysis were performed to test the hypotheses.
    Results: The children living in crowded households had shorter sleep durations (β = -0.03, p < .001). Superior housing quality and family functioning were associated with longer sleep durations (β = 0.04 and 0.02, respectively, ps < .01). The effects of housing quality and family functioning on sleep duration were mediated by maternal mental health.
    Conclusions: Both physical and social characteristics of the family environment are critical to sleep duration in children. The effects of family environment characteristics on sleep duration in children are in part mediated by maternal mental health. Interventions to improve sleep during childhood by targeting the family environment may be more effective when maternal mental health is considered.
    Mesh-Begriff(e) Child ; Humans ; Family Characteristics ; Mental Health ; Cohort Studies ; Crowding ; Sleep
    Sprache Englisch
    Erscheinungsdatum 2022-10-13
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 4766-1
    ISSN 1873-5347 ; 0037-7856 ; 0277-9536
    ISSN (online) 1873-5347
    ISSN 0037-7856 ; 0277-9536
    DOI 10.1016/j.socscimed.2022.115450
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 625: Hefte anzeigen Standort:
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  9. Artikel ; Online: On Decoder Ties for the Binary Symmetric Channel with Arbitrarily Distributed Input.

    Chang, Ling-Hua / Chen, Po-Ning / Alajaji, Fady

    Entropy (Basel, Switzerland)

    2023  Band 25, Heft 4

    Abstract: The error probability of block codes sent under a non-uniform input distribution over the memoryless binary symmetric channel (BSC) and decoded via the maximum a posteriori (MAP) decoding rule is investigated. It is proved that the ratio of the ... ...

    Abstract The error probability of block codes sent under a non-uniform input distribution over the memoryless binary symmetric channel (BSC) and decoded via the maximum a posteriori (MAP) decoding rule is investigated. It is proved that the ratio of the probability of MAP decoder ties to the probability of error grows most linearly in blocklength when no MAP decoding ties occur, thus showing that decoder ties do not affect the code's error exponent. This result generalizes a similar recent result shown for the case of block codes transmitted over the BSC under a uniform input distribution.
    Sprache Englisch
    Erscheinungsdatum 2023-04-16
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e25040668
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Entering the error-corrected quantum era.

    Chen, Zijie / Sun, Luyan / Zou, Chang-Ling

    Science bulletin

    2023  Band 68, Heft 10, Seite(n) 961–963

    Sprache Englisch
    Erscheinungsdatum 2023-05-02
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2816140-3
    ISSN 2095-9281 ; 2095-9273
    ISSN (online) 2095-9281
    ISSN 2095-9273
    DOI 10.1016/j.scib.2023.04.039
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