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  1. Article ; Online: Increasing legionella in Taiwan during COVID-19 pandemic.

    Chao, Chien-Ming / Lai, Chih-Cheng

    American journal of infection control

    2022  Volume 50, Issue 2, Page(s) 237–238

    MeSH term(s) COVID-19 ; Humans ; Legionella ; Pandemics ; SARS-CoV-2 ; Taiwan/epidemiology
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2021.10.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Epidemiology of extended-spectrum β-lactamases in

    Chao, Chien-Ming / Lai, Chih-Cheng / Yu, Wen-Liang

    Frontiers in microbiology

    2023  Volume 13, Page(s) 1060050

    Abstract: The emergence of antimicrobial resistance among microorganisms is a serious public health concern, and extended-spectrum β-lactamases (ESBL)- ... ...

    Abstract The emergence of antimicrobial resistance among microorganisms is a serious public health concern, and extended-spectrum β-lactamases (ESBL)-producing
    Language English
    Publishing date 2023-01-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.1060050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Effect on Combination Therapy and Antibiotic Duration.

    Chao, Chien-Ming / Lai, Chih-Cheng

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2021  Volume 73, Issue 8, Page(s) 1552

    MeSH term(s) Administration, Oral ; Anti-Bacterial Agents/therapeutic use ; Combined Modality Therapy ; Humans
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-05-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciab388
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Collateral Effect of COVID-19 on the Epidemiology of Airborne/Droplet-Transmitted Notifiable Infectious Diseases in Taiwan.

    Tang, Hung-Jen / Lai, Chih-Cheng / Chao, Chien-Ming

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 4

    Abstract: This study was conducted to compare the number of cases of airborne/droplet-transmitted notifiable infectious disease (NID) between the pandemic period (defined as from January 2020 to December 2021) and the pre-pandemic period (defined as the period ... ...

    Abstract This study was conducted to compare the number of cases of airborne/droplet-transmitted notifiable infectious disease (NID) between the pandemic period (defined as from January 2020 to December 2021) and the pre-pandemic period (defined as the period from January 2018 to December 2019). The annual case numbers of airborne/droplet-transmitted NIDs from 2018 to 2021 were collected for comparison. Fourteen airborne/droplet-transmitted NIDs including measles, rubella, pertussis, influenza with severe complications, invasive pneumococcal diseases (IPD), Q fever, mumps, meningococcal meningitis, varicella, legionellosis, invasive Haemophilus influenzae type b infection, hantavirus syndrome, TB, and multidrug-resistant TB (MDRTB), were included for the analysis. Overall, the annual case number of these 14 airborne/droplet-transmitted NID was 11,930, 12,747, 9477, and 8268 in 2018, 2019, 2020, and 2021, respectively, and the overall incidence was 50.3, 53.6, 39.8, 34.6 per 100,000 populations in in 2018, 2019, 2020, and 2021. The case number of influenza with severe complications had the largest reduction from the pre-pandemic period to the pandemic period, with a reduction of 3076 cases, followed by TB (-2904), IPD (-490), mumps (-292), measles (-292), pertussis (-57), MDRTB (-43), rubella (-35), Q fever (-20), varicella (-12), meningococcal meningitis (-5), invasive
    Language English
    Publishing date 2022-04-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11040478
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Changing Epidemiology of Respiratory Tract Infection during COVID-19 Pandemic.

    Tang, Hung-Jen / Lai, Chih-Cheng / Chao, Chien-Ming

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 3

    Abstract: The outbreak of COVID-19 has significantly changed the epidemiology of respiratory tract infection in several ways. The implementation of non-pharmaceutical interventions (NPIs) including universal masking, hand hygiene, and social distancing not only ... ...

    Abstract The outbreak of COVID-19 has significantly changed the epidemiology of respiratory tract infection in several ways. The implementation of non-pharmaceutical interventions (NPIs) including universal masking, hand hygiene, and social distancing not only resulted in a decline in reported SARS-CoV-2 cases but also contributed to the decline in the non-COVID-19 respiratory tract infection-related hospital utilization. Moreover, it also led to the decreased incidence of previous commonly encountered respiratory pathogens, such as influenza and
    Language English
    Publishing date 2022-02-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11030315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Inhaled ciclesonide for outpatients with COVID-19: A meta-analysis.

    Hsu, Chi-Kuei / Chao, Chien-Ming / Lai, Chih-Cheng

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2022  

    Language English
    Publishing date 2022-08-08
    Publishing country England
    Document type Letter
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    DOI 10.1016/j.jmii.2022.08.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19 associated mucormycosis - An emerging threat.

    Chao, Chien-Ming / Lai, Chih-Cheng / Yu, Wen-Liang

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2022  Volume 55, Issue 2, Page(s) 183–190

    Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly become a global threaten since its emergence in the end of 2019. Moreover, SARS-CoV-2 infection could also present with co-infection or ... ...

    Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly become a global threaten since its emergence in the end of 2019. Moreover, SARS-CoV-2 infection could also present with co-infection or secondary infection by other virus, bacteria, or fungi. Among them, mucormycosis is a rare but aggressive fungal disease and it mainly affects patients particularly with poorly controlled diabetes mellitus with diabetic ketoacidosis (DKA). We here did a comprehensive review of literature reporting COVID-19 associated with mucormycosis (CAM) cases, which have been reported worldwide. The prevalence is higher in India, Iran, and Egypt than other countries, particularly highest in the states of Gujarat and Maharashtra in India. Poor diabetic control and the administration of systemic corticosteroids are the common precipitating factors causing mucormycosis in the severe and critical COVID-19 patients. In addition, COVID-19 itself may affect the immune system resulting in vulnerability of the patients to mucormycosis. Appropriate treatments of CAM include strict glycemic control, extensive surgical debridement, and antifungal therapy with amphotericin B formulations.
    MeSH term(s) Antifungal Agents/therapeutic use ; COVID-19/complications ; Coinfection/drug therapy ; Diabetic Ketoacidosis/complications ; Diabetic Ketoacidosis/epidemiology ; Humans ; India/epidemiology ; Mucormycosis/drug therapy ; Mucormycosis/epidemiology ; SARS-CoV-2
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2022-01-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    DOI 10.1016/j.jmii.2021.12.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: COVID-19 Associated with Cryptococcosis: A New Challenge during the Pandemic.

    Chan, Khee-Siang / Lai, Chih-Cheng / Yu, Wen-Liang / Chao, Chien-Ming

    Journal of fungi (Basel, Switzerland)

    2022  Volume 8, Issue 10

    Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a great threat to global health. In addition to SARS-CoV-2 itself, clinicians should be alert to the possible occurrence of co-infection or ... ...

    Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a great threat to global health. In addition to SARS-CoV-2 itself, clinicians should be alert to the possible occurrence of co-infection or secondary infection among patients with COVID-19. The possible co-pathogens include bacteria, viruses, and fungi, but COVID-19-associated cryptococcosis is rarely reported. This review provided updated and comprehensive information about this rare clinical entity of COVID-19-associated cryptococcosis. Through an updated literature search till 23 August 2022, we identified a total of 18 culture-confirmed case reports with detailed information. Half (n = 9) of them were elderly. Fifteen (83.3%) of them had severe COVID-19 and ever received systemic corticosteroid. Disseminated infection with cryptococcemia was the most common type of cryptococcosis, followed by pulmonary and meningitis. Except one case of
    Language English
    Publishing date 2022-10-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8101111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Optimal Dose of Cefoperazone-Sulbactam for Acute Bacterial Infection in Patients with Chronic Kidney Disease.

    Chao, Chien-Ming / Lai, Chih-Cheng / Lee, Chen-Hsiang / Tang, Hung-Jen

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 5

    Abstract: The optimal dosage of cefoperazone-sulbactam for patients with chronic kidney disease (CKD) remains unclear. This study aimed to investigate two treatment strategies of cefoperazone-sulbactam-2 g/2 g twice daily and adjusted dose according to renal ... ...

    Abstract The optimal dosage of cefoperazone-sulbactam for patients with chronic kidney disease (CKD) remains unclear. This study aimed to investigate two treatment strategies of cefoperazone-sulbactam-2 g/2 g twice daily and adjusted dose according to renal function for patients with CKD. A total of 155 patients with CKD received cefoperazone-sulbactam either at a dose of 2 g/2 g twice daily (study group) or adjusted according to renal function (control group) for the treatment of acute bacterial infection. The primary outcome was the clinical response rate at day 14 and the secondary outcomes included treatment failure and all-cause death. The study group had a higher clinical response rate (80.0% vs. 65.0%) and a lower treatment failure rate (4.0% vs. 23.8%) as compared with the control group. Further multivariable analysis showed that compared with the control group, the study group had a higher clinical response rate (adjusted OR = 4.02; 95% CI, 1.49-10.81) and lower treatment failure rate (adjusted OR = 0.06; 95% CI, 0.01-0.28). In addition, no significant difference in all-cause mortality was observed between the study and the control group (adjusted OR = 1.95; 95% CI, 0.57-6.66). Finally, no significant difference was observed between the study and the control group in the risk of the adverse events (AEs)-diarrhea (
    Language English
    Publishing date 2022-04-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11050610
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Oral Janus kinase inhibitors for treating hospitalized patients with COVID-19: An updated systematic review and meta-analysis of randomized controlled trials.

    Tang, Hung-Jen / Weng, Teng-Song / Chen, Yu-Hung / Chao, Chien-Ming

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2022  

    Abstract: Objectives: This study investigated the clinical efficacy and safety of oral Janus kinase inhibitors (JAKis) in the treatment of hospitalized patients with COVID-19.: Methods: The PubMed, Embase, Cochrane Central Register of Controlled Trials, and ... ...

    Abstract Objectives: This study investigated the clinical efficacy and safety of oral Janus kinase inhibitors (JAKis) in the treatment of hospitalized patients with COVID-19.
    Methods: The PubMed, Embase, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov databases were searched for relevant articles written before January 29, 2022. Only randomized controlled trials (RCTs) that assessed the clinical efficacy and safety of oral JAKis in patients with COVID-19 were included.
    Results: In the pooled analysis of the 7 RCTs, the all-cause 28-day mortality rate in the study group receiving JAKis was significantly lower than that in the control group (9.4% [183/1941] vs. 10.9% [184/1687], risk ratio [RR] = 0.69, 95% confidence interval [CI], 0.58-0.81, I
    Conclusions: Oral JAKis can significantly reduce the risk of death among patients with COVID-19. In addition, JAKis are tolerable for hospitalized patients with COVID-19.
    Language English
    Publishing date 2022-08-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    DOI 10.1016/j.jmii.2022.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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