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Article: Resection and reconstruction for primary sternal tumors.

Chapelier, Alain

2010 Volume 20, Issue 4, Page(s) 529–534

Abstract: Radical resection can offer a definitive cure of primary malignant sternal tumors, but the surgical management may be difficult because of the local aggressiveness of these tumors and a high recurrence rate. This article describes improvements in ... ...

Abstract	Radical resection can offer a definitive cure of primary malignant sternal tumors, but the surgical management may be difficult because of the local aggressiveness of these tumors and a high recurrence rate. This article describes improvements in reconstruction techniques with musculocutaneous flaps that have made coverage of wide sternal defects reliable. A rigid reinforcement of the sternum can now be achieved with titanium bars and clips after a total sternectomy. Large sternal defects are safely reconstructed with a musculocutaneous flap. The completeness of the resection and the histologic grade of the tumors are the strongest survival predictors.
MeSH term(s)	Bone Neoplasms/diagnosis ; Bone Neoplasms/pathology ; Bone Neoplasms/surgery ; Humans ; Manubrium/pathology ; Manubrium/surgery ; Reconstructive Surgical Procedures ; Sternum ; Surgical Flaps
Language	English
Publishing date	2010-11
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2149218-9
ISSN	1558-5069 ; 1547-4127
ISSN (online)	1558-5069
ISSN	1547-4127
DOI	10.1016/j.thorsurg.2010.06.002
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Article ; Online: Use of 3-dimensional computed tomography for planning a complex sleeve bronchoplasty with total parenchyma-sparing resection of a carcinoid tumour in the right main bronchus.

Betser, Léa / De Wolf, Julien / Glorion, Matthieu / Chapelier, Alain

Interactive cardiovascular and thoracic surgery

2019 Volume 29, Issue 4, Page(s) 638–640

Abstract: Bronchoplasty is frequently required for radical resection of central typical carcinoid tumours. As sleeve bronchoplasty can be a complex procedure, an accurate evaluation of the tumour location is mandatory. Although the endobronchial part of the tumour ...

Abstract	Bronchoplasty is frequently required for radical resection of central typical carcinoid tumours. As sleeve bronchoplasty can be a complex procedure, an accurate evaluation of the tumour location is mandatory. Although the endobronchial part of the tumour can be easily evaluated by bronchoscopy, the exo-bronchial part is difficult to analyse with a standard computed tomography (CT) scan. A three-dimensional (3D) CT scan could be used to identify this exo-bronchial component of the tumour when planning a reconstruction. Herein, we present a case of a 59-year-old woman with a typical central carcinoid tumour of the right main bronchus. After 3D modelling, we successfully performed a total parenchyma-sparing resection with an intermedius bronchus reimplantation into the carina associated with the right upper bronchus anastomosis in the lateral trachea. The follow-up was uneventful. An endoscopy at 3 months showed excellent results.
MeSH term(s)	Anastomosis, Surgical ; Bronchial Neoplasms/diagnostic imaging ; Bronchial Neoplasms/surgery ; Carcinoid Tumor/diagnostic imaging ; Carcinoid Tumor/surgery ; Humans ; Imaging, Three-Dimensional ; Male ; Middle Aged ; Reconstructive Surgical Procedures ; Surgery, Computer-Assisted ; Thoracic Surgical Procedures ; Tomography, X-Ray Computed ; Trachea/surgery
Language	English
Publishing date	2019-05-21
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivz124
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Zs.A 5730: Show issues

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Article ; Online: A Horseshoe Intralobar Lung Sequestration Resection by Bilateral Robot-Assisted Surgery.

Dagorno, Claire / Sarsam, Matthieu / Brun, Anne-Laure / Longchampt, Elisabeth / Sage, Edouard / Chapelier, Alain / Glorion, Matthieu

The Annals of thoracic surgery

2021 Volume 113, Issue 2, Page(s) e95–e97

Abstract: We present the case of a 20-year-old male patient presenting a right lower intralobar pulmonary "horseshoe" sequestration extending into the left cavity supplied by 4 aberrant arteries from the thoracic descending aorta. The surgical approach for this ... ...

Abstract	We present the case of a 20-year-old male patient presenting a right lower intralobar pulmonary "horseshoe" sequestration extending into the left cavity supplied by 4 aberrant arteries from the thoracic descending aorta. The surgical approach for this exceptional and challenging presentation was based on thorough analysis of the chest computed tomography scan aided by 3-dimensional reconstructions. The latter helped us better understand this complex malformation. Surgery was done by robot-assisted bilateral approach with en bloc extraction through the left side.
MeSH term(s)	Bronchopulmonary Sequestration/diagnosis ; Bronchopulmonary Sequestration/surgery ; Humans ; Male ; Pneumonectomy/methods ; Robotic Surgical Procedures/methods ; Thoracic Surgery, Video-Assisted/methods ; Tomography, X-Ray Computed ; Young Adult
Language	English
Publishing date	2021-04-28
Publishing country	Netherlands
Document type	Case Reports ; Video-Audio Media
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2021.04.040
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Article ; Online: Results of Lung Transplantation for Cystic Fibrosis With Selected Donors Over 65 Years Old.

Glorion, Matthieu / Sarsam, Matthieu / Roux, Antoine / Stern, Marc / Belousova, Natalia / Fessler, Julien / Pricopi, Ciprian / De Wolf, Julien / Picard, Clement / Brugière, Olivier / De Miranda, Sandra / Grenet, Dominique / Tachon, Guillaume / Cerf, Charles / Parquin, Francois / Le Guen, Morgan / Chapelier, Alain / Vallée, Alexandre / Sage, Edouard

Transplant international : official journal of the European Society for Organ Transplantation

2023 Volume 36, Page(s) 11180

Abstract: Lung transplantation is limited by the shortage of suitable donors. Many programs have begun to use extended criteria donors. Donors over 65 years old are rarely reported, especially for young cystic fibrosis recipients. This monocentric study was ... ...

Abstract	Lung transplantation is limited by the shortage of suitable donors. Many programs have begun to use extended criteria donors. Donors over 65 years old are rarely reported, especially for young cystic fibrosis recipients. This monocentric study was conducted for cystic fibrosis recipients from January 2005 to December 2019, comparing two cohorts according to lung donor age (<65 years or ≥65 years). The primary objective was to assess the survival rate at 3 years using a Cox multivariable model. Of the 356 lung recipients, 326 had donors under 65 years, and 30 had donors over 65 years. Donors' characteristics did not differ significantly in terms of sex, time on mechanical ventilation before retrieval, and partial pressure of arterial oxygen/fraction of inspired oxygen ratio. There were no significant differences in post-operative mechanical ventilation duration and incidence of grade 3 primary graft dysfunction between the two groups. At 1, 3, and 5 years, the percentage of predicted forced expiratory volume in 1 s (
MeSH term(s)	Humans ; Aged ; Cystic Fibrosis/surgery ; Tissue and Organ Procurement ; Retrospective Studies ; Treatment Outcome ; Tissue Donors ; Lung Transplantation/methods ; Lung ; Oxygen
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2023-06-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	639435-8
ISSN	1432-2277 ; 0934-0874
ISSN (online)	1432-2277
ISSN	0934-0874
DOI	10.3389/ti.2023.11180
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Article ; Online: The role of three-dimensional reconstructions in understanding the intersegmental plane: an anatomical study of segment 6.

Sarsam, Matthieu / Glorion, Matthieu / de Wolf, Julien / Cassiano, Francesco / Puyo, Philippe / Sage, Edouard / Chapelier, Alain

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

2020 Volume 58, Issue 4, Page(s) 763–767

Abstract: Objectives: The identification of the intersegmental plane during lung segmentectomies remains a practical difficulty, notably with minimally invasive approaches. The intraoperative techniques are based on demarcating either the bronchial or the ... ...

Abstract	Objectives: The identification of the intersegmental plane during lung segmentectomies remains a practical difficulty, notably with minimally invasive approaches. The intraoperative techniques are based on demarcating either the bronchial or the vascular territories. The goal of this study was to evaluate the use of 3-dimensional reconstructions in understanding the intersegmental plane of segment 6. Methods: Between March and September 2018, Synapse 3-dimensional programme was used to carry out bilateral venous, arterial and bronchial segmentations of segment 6. All computed tomography (CT) scans were contrast-enhanced and of a high resolution (0.6 mm slices). The patients had normal results on respiratory function tests. The volumes obtained from each of the 3 modalities were then compared. The results are presented as mean and standard deviation and as median and interquartile ranges for lung volume measurements. Results: During the aforementioned period, 15 high-resolution chest CT scans were selected (8 men and 7 women). The median age was 70 years. In all of the studied segments (N = 30, 15 right S6 and 15 left S6), the segmental volume of the vein was greater than the segmental volumes of the bronchus and the artery. A significant difference was found between the segmental volumes obtained from the 3 modalities (P = 0.001). The segmental volume of the vein was significantly higher than the segmental volume of the bronchus (P < 0.001) and the segmental volume of the artery (P < 0.001). On the other hand, the segmental volume of the artery was significantly higher than the segmental volume of the bronchus (P = 0.01). Conclusions: Within the limits of this study, the segmental venous volume of S6 was greater than the volumes of the segmental bronchial and arterial volumes. Thus, depending solely on bronchial techniques might lead to leaving a border zone in venous congestion.
MeSH term(s)	Aged ; Female ; Humans ; Imaging, Three-Dimensional ; Lung/diagnostic imaging ; Lung Neoplasms/surgery ; Male ; Pneumonectomy ; Tomography, X-Ray Computed
Language	English
Publishing date	2020-05-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	639293-3
ISSN	1873-734X ; 1010-7940 ; 1567-4258
ISSN (online)	1873-734X
ISSN	1010-7940 ; 1567-4258
DOI	10.1093/ejcts/ezaa123
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Article ; Online: Optimal Management With Radical Resection of Obstructive Primary Chondrosarcoma of the Trachea.

Moret, Aurélien / Glorion, Matthieu / Gonin, François / Longchampt, Elisabeth / Colin, Charlotte / Mignon, François / Sage, Edouard / Chapelier, Alain

The Annals of thoracic surgery

2020 Volume 111, Issue 6, Page(s) e393–e395

Abstract: We report 2 cases of chondrosarcoma of the trachea. This etiology of tracheal tumors is exceptional, and only a few cases have been reported so far. The optimal management for these 2 cases was challenging. First an interventional bronchoscopy was ... ...

Abstract	We report 2 cases of chondrosarcoma of the trachea. This etiology of tracheal tumors is exceptional, and only a few cases have been reported so far. The optimal management for these 2 cases was challenging. First an interventional bronchoscopy was required for biopsy and to prevent airway obstruction. Second a radical en bloc resection with free margins was performed through a sternotomy in the first case and by a cervicotomy in the second case. Fifty and 6 months after surgery the 2 patients are alive with no local or distant recurrence.
MeSH term(s)	Aged ; Airway Obstruction/etiology ; Chondrosarcoma/complications ; Chondrosarcoma/surgery ; Female ; Humans ; Male ; Tracheal Neoplasms/complications ; Tracheal Neoplasms/surgery ; Tracheotomy
Language	English
Publishing date	2020-12-19
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2020.09.066
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Article ; Online: Radical Carinal Resection for a Glomic Tumor.

Bellier, Jocelyn / Sage, Edouard / Gonin, François / Longchampt, Elisabeth / Chapelier, Alain

The Annals of thoracic surgery

2016 Volume 102, Issue 2, Page(s) e143–5

Abstract: We report the case of a 33-year-old woman who presented with increasing dyspnea secondary to a tumor arising from the carina. After desobstruction by bronchoscopy, the pathologic analysis revealed a glomic tumor. Carinal resection and reconstruction were ...

Abstract	We report the case of a 33-year-old woman who presented with increasing dyspnea secondary to a tumor arising from the carina. After desobstruction by bronchoscopy, the pathologic analysis revealed a glomic tumor. Carinal resection and reconstruction were performed with venoarterial extracorporeal membrane oxygenation support. The patient's postoperative course was uneventful, and the long-term result was excellent.
MeSH term(s)	Adult ; Bronchoscopy/methods ; Dyspnea/diagnosis ; Dyspnea/etiology ; Extracorporeal Membrane Oxygenation/methods ; Female ; Follow-Up Studies ; Glomus Tumor/diagnostic imaging ; Glomus Tumor/surgery ; Humans ; Rare Diseases ; Reconstructive Surgical Procedures/methods ; Risk Assessment ; Sternotomy/methods ; Tomography, X-Ray Computed/methods ; Trachea/surgery ; Tracheal Neoplasms/diagnostic imaging ; Tracheal Neoplasms/surgery ; Treatment Outcome
Language	English
Publishing date	2016-08
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2016.01.023
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Article ; Online: Extracorporeal membrane oxygenation for grade 3 primary graft dysfunction after lung transplantation: Long-term outcomes.

Bellier, Jocelyn / Lhommet, Pierre / Bonnette, Pierre / Puyo, Philippe / Le Guen, Morgan / Roux, Antoine / Parquin, François / Chapelier, Alain / Sage, Edouard

Clinical transplantation

2019 Volume 33, Issue 3, Page(s) e13480

Abstract: Introduction: Extracorporeal membrane oxygenation (ECMO) is an efficient and innovative therapeutic tool for primary graft dysfunction (PGD). However, its effect on survival and long-term lung function is not well known. This study evaluated those ... ...

Abstract	Introduction: Extracorporeal membrane oxygenation (ECMO) is an efficient and innovative therapeutic tool for primary graft dysfunction (PGD). However, its effect on survival and long-term lung function is not well known. This study evaluated those parameters in patients with PGD requiring ECMO. Method: This single-center, retrospective study included patients who underwent LTx at our institute between January 2007 and December 2013. Patients and disease characteristics, survival, and pulmonary function tests were recorded. Results: A total of 309 patients underwent LTx during the study period and 211 were included. The patients were predominantly male (53.5%), the median age was 39 years, and the primary pathology was suppurative disease (53.1%). ECMO for PGD was mandatory in 24 (11.7%) cases. Mortality at 3 months in the ECMO group was 50% (N = 12). However, long-term survival after PGD did not correlate with ECMO. Forced expiratory volume and vital capacity were significantly reduced in patients with PGD requiring ECMO, especially those with idiopathic pulmonary fibrosis. Conclusion: Veno-arterial ECMO appears to be suitable for management of PGD after LTx. Patients with PGD requiring ECMO show increased initial mortality; however, long-term survival was comparable with that of other patients in the study. Lung function does not appear to be related to PGD requiring ECMO.
MeSH term(s)	Adolescent ; Adult ; Aged ; Extracorporeal Membrane Oxygenation/mortality ; Female ; Follow-Up Studies ; Forced Expiratory Volume ; Graft Survival ; Humans ; Lung Transplantation/adverse effects ; Lung Transplantation/mortality ; Male ; Middle Aged ; Postoperative Complications ; Primary Graft Dysfunction/diagnosis ; Primary Graft Dysfunction/etiology ; Primary Graft Dysfunction/immunology ; Prognosis ; Respiratory Function Tests ; Retrospective Studies ; Risk Factors ; Survival Rate ; Young Adult
Language	English
Publishing date	2019-02-21
Publishing country	Denmark
Document type	Clinical Trial ; Journal Article
ZDB-ID	639001-8
ISSN	1399-0012 ; 0902-0063
ISSN (online)	1399-0012
ISSN	0902-0063
DOI	10.1111/ctr.13480
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Article ; Online: Cannabis use and lung cancer: time to stop overlooking the problem?

Betser, Léa / Glorion, Matthieu / Mordant, Pierre / Caramella, Caroline / Ghigna, Maria-Rosa / Besse, Benjamin / Planchard, David / Le Pavec, Jérome / Chapelier, Alain / Friard, Sylvie / Gounant, Valérie / Castier, Yves / Levy, Antonin / Mercier, Olaf / Fabre, Dominique / Fadel, Elie / Pradere, Pauline

The European respiratory journal

2021 Volume 57, Issue 5

MeSH term(s)	Cannabis ; Humans ; Lung Neoplasms ; Marijuana Smoking
Language	English
Publishing date	2021-05-20
Publishing country	England
Document type	Letter
ZDB-ID	639359-7
ISSN	1399-3003 ; 0903-1936
ISSN (online)	1399-3003
ISSN	0903-1936
DOI	10.1183/13993003.04132-2020
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Article ; Online: Real-Time Computed Tomography Highlights Pulmonary Parenchymal Evolution During Ex Vivo Lung Reconditioning.

Sage, Edouard / De Wolf, Julien / Puyo, Philippe / Bonnette, Pierre / Glorion, Matthieu / Salley, Nicolas / Roux, Antoine / Liu, Ngai / Chapelier, Alain

The Annals of thoracic surgery

2017 Volume 103, Issue 6, Page(s) e535–e537

Abstract: Ex vivo lung perfusion (EVLP) has been developed as a method to reassess and recondition marginal lungs. However, evaluation during procedures is limited to a combination of physiologic variables such as gas exchange, pulmonary mechanics, and pulmonary ... ...

Abstract	Ex vivo lung perfusion (EVLP) has been developed as a method to reassess and recondition marginal lungs. However, evaluation during procedures is limited to a combination of physiologic variables such as gas exchange, pulmonary mechanics, and pulmonary vascular resistance. The aim of this study was to analyze the feasibility of real-time computed tomographic (CT) imaging to improve the evaluation of the lung during EVLP procedures.
MeSH term(s)	Donor Selection ; Humans ; Lung Transplantation ; Organ Preservation ; Tomography, X-Ray Computed ; Transplantation Conditioning
Language	English
Publishing date	2017-06
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2016.12.029
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