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  1. Article ; Online: Effect of Children’s Weight Status on Physical Activity and Sedentary Behavior during Physical Education, Recess, and After School

    Zachary C. Pope / Charles Huang / David Stodden / Daniel J. McDonough / Zan Gao

    Journal of Clinical Medicine, Vol 9, Iss 2651, p

    2020  Volume 2651

    Abstract: Children’s body mass index may affect physical activity (PA) participation. Therefore, this study examined the effect of children’s weight status on underserved elementary school children’s PA and sedentary behavior (SB) throughout the segmented day. ... ...

    Abstract Children’s body mass index may affect physical activity (PA) participation. Therefore, this study examined the effect of children’s weight status on underserved elementary school children’s PA and sedentary behavior (SB) throughout the segmented day. Participants were 138 children ( <math display="inline"><semantics><mover><mi mathvariant="normal">X</mi><mo>¯</mo></mover></semantics></math> age = 8.14 years). Children’s height and weight were measured with subsequent classification of children as healthy weight or overweight/obese. Durations of moderate-to-vigorous PA (MVPA), light PA (LPA), and SB during physical education (PE), morning recess, lunch recess, after school, and overall were assessed via accelerometry over three days. Independent t-tests evaluated differences in children’s MVPA, LPA, and SB during each daily segment by weight status. Significantly higher MVPA was observed for children of healthy weight status versus children with overweight/obesity during morning recess, t (136) = 2.15, p = 0.03, after school, t (136) = 2.68, p < 0.01, and overall, t (136) = 2.65, p < 0.01. Interestingly, comparisons of children of healthy weight status and children with overweight/obesity’s LPA and SB during the after-school segment revealed a trend wherein children with overweight/obesity participated in slightly greater LPA/less SB than children of healthy weight status. Higher MVPA was observed among children of healthy weight versus children with overweight/obesity during most daily segments. Concerted efforts should focus on increasing MVPA among children with overweight/obesity.
    Keywords accelerometry ; body mass index ; obesity ; overweight ; pediatrics ; physical activity ; Medicine ; R
    Subject code 796
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Whole transcriptome–based skin virome profiling in typical epidermodysplasia verruciformis reveals α-, β-, and γ-HPV infections

    Amir Hossein Saeidian / Leila Youssefian / Mahtab Naji / Hamidreza Mahmoudi / Samantha M. Barnada / Charles Huang / Karim Naghipoor / Amir Hozhabrpour / Jason S. Park / Flavia Manzo Margiotta / Fatemeh Vahidnezhad / Zahra Saffarian / Kambiz Kamyab-Hesari / Mohammad Tolouei / Niloofar Faraji / Seyyede Zeinab Azimi / Ghazal Namdari / Parvin Mansouri / Jean-Laurent Casanova /
    Vivien Béziat / Emmanuelle Jouanguy / Jouni Uitto / Hassan Vahidnezhad

    JCI Insight, Vol 8, Iss

    2023  Volume 5

    Abstract: HPVs are DNA viruses include approximately 450 types that are classified into 5 genera (α-, β-, γ-, μ-, and ν-HPV). The γ- and β-HPVs are present in low copy numbers in healthy individuals; however, in patients with an inborn error of immunity, certain ... ...

    Abstract HPVs are DNA viruses include approximately 450 types that are classified into 5 genera (α-, β-, γ-, μ-, and ν-HPV). The γ- and β-HPVs are present in low copy numbers in healthy individuals; however, in patients with an inborn error of immunity, certain species of β-HPVs can cause epidermodysplasia verruciformis (EV), manifesting as recalcitrant cutaneous warts and skin cancer. EV presents as either typical or atypical. Manifestations of typical EV are limited to the skin and are caused by abnormal keratinocyte-intrinsic immunity to β-HPVs due to pathogenic sequence variants in TMC6, TMC8, or CIB1. We applied a transcriptome-based computational pipeline, VirPy, to RNA extracted from normal-appearing skin and wart samples of patients with typical EV to explore the viral and human genetic determinants. In 26 patients, 9 distinct biallelic mutations were detected in TMC6, TMC8, and CIB1, 7 of which are previously unreported to our knowledge. Additionally, 20 different HPV species, including 3 α-HPVs, 16 β-HPVs, and 1 γ-HPV, were detected, 8 of which are reported here for the first time to our knowledge in patients with EV (β-HPV-37, -47, -80, -151, and -159; α-HPV-2 and -57; and γ-HPV-128). This study expands the TMC6, TMC8, and CIB1 sequence variant spectrum and implicates new HPV subtypes in the pathogenesis of typical EV.
    Keywords Dermatology ; Genetics ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher American Society for Clinical investigation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Exploring scenarios of light pollution from coastal development reaching sea turtle nesting beaches near Cabo Pulmo, Mexico

    Gregory M. Verutes / Charles Huang / Ricardo Rodríguez Estrella / Kara Loyd

    Global Ecology and Conservation, Vol 2, Iss , Pp 170-

    2014  Volume 180

    Abstract: New coastal development may offer economic benefits to resort builders and even local communities, but these projects can also impact local ecosystems, key wildlife, and the draw for tourists. We explore how light from Cabo Cortés, a proposed coastal ... ...

    Abstract New coastal development may offer economic benefits to resort builders and even local communities, but these projects can also impact local ecosystems, key wildlife, and the draw for tourists. We explore how light from Cabo Cortés, a proposed coastal development in Baja California Sur, Mexico, may alter natural light cues used by sea turtle hatchlings. We adapt a viewshed approach to model exterior light originating from the resort under plausible zoning scenarios. This spatially explicit information allows stakeholders to evaluate the likely impact of alternative development options. Our model suggests that direct light’s ability to reach sea turtle nesting beaches varies greatly by source location and height—with some plausible development scenarios leading to significantly less light pollution than others. Our light pollution maps can enhance decision-making, offering clear guidance on where to avoid elevated lamps or when to recommend lighting restrictions. Communities can use this information to participate in development planning to mitigate ecological, aesthetic and economic impacts from artificial lighting. Though tested in Mexico, our approach and free, open-source software can be applied in other places around the world to better understand and manage the threats of light pollution to sea turtles. Keywords: Artificial light, Viewshed analysis, Sea turtle conservation, Coastal resort management, InVEST
    Keywords Ecology ; QH540-549.5
    Subject code 333
    Language English
    Publishing date 2014-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge.

    Imanuel Lerman / Bryan Davis / Mingxiong Huang / Charles Huang / Linda Sorkin / James Proudfoot / Edward Zhong / Donald Kimball / Ramesh Rao / Bruce Simon / Andrea Spadoni / Irina Strigo / Dewleen G Baker / Alan N Simmons

    PLoS ONE, Vol 14, Iss 2, p e

    2019  Volume 0201212

    Abstract: The mechanisms by which noninvasive vagal nerve stimulation (nVNS) affect central and peripheral neural circuits that subserve pain and autonomic physiology are not clear, and thus remain an area of intense investigation. Effects of nVNS vs sham ... ...

    Abstract The mechanisms by which noninvasive vagal nerve stimulation (nVNS) affect central and peripheral neural circuits that subserve pain and autonomic physiology are not clear, and thus remain an area of intense investigation. Effects of nVNS vs sham stimulation on subject responses to five noxious thermal stimuli (applied to left lower extremity), were measured in 30 healthy subjects (n = 15 sham and n = 15 nVNS), with fMRI and physiological galvanic skin response (GSR). With repeated noxious thermal stimuli a group × time analysis showed a significantly (p < .001) decreased response with nVNS in bilateral primary and secondary somatosensory cortices (SI and SII), left dorsoposterior insular cortex, bilateral paracentral lobule, bilateral medial dorsal thalamus, right anterior cingulate cortex, and right orbitofrontal cortex. A group × time × GSR analysis showed a significantly decreased response in the nVNS group (p < .0005) bilaterally in SI, lower and mid medullary brainstem, and inferior occipital cortex. Finally, nVNS treatment showed decreased activity in pronociceptive brainstem nuclei (e.g. the reticular nucleus and rostral ventromedial medulla) and key autonomic integration nuclei (e.g. the rostroventrolateral medulla, nucleus ambiguous, and dorsal motor nucleus of the vagus nerve). In aggregate, noninvasive vagal nerve stimulation reduced the physiological response to noxious thermal stimuli and impacted neural circuits important for pain processing and autonomic output.
    Keywords Medicine ; R ; Science ; Q
    Subject code 150
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Exploring scenarios of light pollution from coastal development reaching sea turtle nesting beaches near Cabo Pulmo, Mexico

    Verutes, Gregory M / Charles Huang / Ricardo Rodríguez Estrella / Kara Loyd

    Global Ecology and Conservation. 2014 Dec., v. 2

    2014  

    Abstract: New coastal development may offer economic benefits to resort builders and even local communities, but these projects can also impact local ecosystems, key wildlife, and the draw for tourists. We explore how light from Cabo Cortés, a proposed coastal ... ...

    Abstract New coastal development may offer economic benefits to resort builders and even local communities, but these projects can also impact local ecosystems, key wildlife, and the draw for tourists. We explore how light from Cabo Cortés, a proposed coastal development in Baja California Sur, Mexico, may alter natural light cues used by sea turtle hatchlings. We adapt a viewshed approach to model exterior light originating from the resort under plausible zoning scenarios. This spatially explicit information allows stakeholders to evaluate the likely impact of alternative development options. Our model suggests that direct light’s ability to reach sea turtle nesting beaches varies greatly by source location and height—with some plausible development scenarios leading to significantly less light pollution than others. Our light pollution maps can enhance decision-making, offering clear guidance on where to avoid elevated lamps or when to recommend lighting restrictions. Communities can use this information to participate in development planning to mitigate ecological, aesthetic and economic impacts from artificial lighting. Though tested in Mexico, our approach and free, open-source software can be applied in other places around the world to better understand and manage the threats of light pollution to sea turtles.
    Keywords aesthetics ; beaches ; computer software ; decision making ; economic impact ; ecosystems ; financial economics ; lamps ; models ; nesting ; planning ; pollution ; sea turtles ; solar radiation ; stakeholders ; tourists ; wildlife ; zoning ; Mexico
    Language English
    Dates of publication 2014-12
    Size p. 170-180.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 2814786-8
    ISSN 2351-9894
    ISSN 2351-9894
    DOI 10.1016/j.gecco.2014.09.001
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Delineating Biophysical Environments of the Sunda Banda Seascape, Indonesia

    Mingshu Wang / Gabby N. Ahmadia / Iliana Chollett / Charles Huang / Helen Fox / Anton Wijonarno / Marguerite Madden

    International Journal of Environmental Research and Public Health, Vol 12, Iss 2, Pp 1069-

    2015  Volume 1082

    Abstract: The Sunda Banda Seascape (SBS), located in the center of the Coral Triangle, is a global center of marine biodiversity and a conservation priority. We proposed the first biophysical environmental delineation of the SBS using globally available satellite ... ...

    Abstract The Sunda Banda Seascape (SBS), located in the center of the Coral Triangle, is a global center of marine biodiversity and a conservation priority. We proposed the first biophysical environmental delineation of the SBS using globally available satellite remote sensing and model-assimilated data to categorize this area into unique and meaningful biophysical classes. Specifically, the SBS was partitioned into eight biophysical classes characterized by similar sea surface temperature, chlorophyll a concentration, currents, and salinity patterns. Areas within each class were expected to have similar habitat types and ecosystem functions. Our work supplemented prevailing global marine management schemes by focusing in on a regional scale with finer spatial resolution. It also provided a baseline for academic research, ecological assessments and will facilitate marine spatial planning and conservation activities in the area. In addition, the framework and methods of delineating biophysical environments we presented can be expanded throughout the whole Coral Triangle to support research and conservation activities in this important region.
    Keywords biophysical environments ; Sunda Banda Seascape ; remote sensing ; self-organizing map ; sea surface temperature ; chlorophyll a ; currents ; salinity ; marine conservation ; Medicine ; R
    Subject code 333
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Walk on the wild side

    Andrew Balmford / Jonathan M H Green / Michael Anderson / James Beresford / Charles Huang / Robin Naidoo / Matt Walpole / Andrea Manica

    PLoS Biology, Vol 13, Iss 2, p e

    estimating the global magnitude of visits to protected areas.

    2015  Volume 1002074

    Abstract: How often do people visit the world's protected areas (PAs)? Despite PAs covering one-eighth of the land and being a major focus of nature-based recreation and tourism, we don't know. To address this, we compiled a globally-representative database of ... ...

    Abstract How often do people visit the world's protected areas (PAs)? Despite PAs covering one-eighth of the land and being a major focus of nature-based recreation and tourism, we don't know. To address this, we compiled a globally-representative database of visits to PAs and built region-specific models predicting visit rates from PA size, local population size, remoteness, natural attractiveness, and national income. Applying these models to all but the very smallest of the world's terrestrial PAs suggests that together they receive roughly 8 billion (8 x 109) visits/y-of which more than 80% are in Europe and North America. Linking our region-specific visit estimates to valuation studies indicates that these visits generate approximately US $600 billion/y in direct in-country expenditure and US $250 billion/y in consumer surplus. These figures dwarf current, typically inadequate spending on conserving PAs. Thus, even without considering the many other ecosystem services that PAs provide to people, our findings underscore calls for greatly increased investment in their conservation.
    Keywords Biology (General) ; QH301-705.5
    Subject code 333
    Language English
    Publishing date 2015-02-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The Coral Triangle Atlas

    Annick Cros / Nurulhuda Ahamad Fatan / Alan White / Shwu Jiau Teoh / Stanley Tan / Christian Handayani / Charles Huang / Nate Peterson / Ruben Venegas Li / Hendra Yusran Siry / Ria Fitriana / Jamison Gove / Tomoko Acoba / Maurice Knight / Renerio Acosta / Neil Andrew / Doug Beare

    PLoS ONE, Vol 9, Iss 6, p e

    an integrated online spatial database system for improving coral reef management.

    2014  Volume 96332

    Abstract: In this paper we describe the construction of an online GIS database system, hosted by WorldFish, which stores bio-physical, ecological and socio-economic data for the 'Coral Triangle Area' in South-east Asia and the Pacific. The database has been built ... ...

    Abstract In this paper we describe the construction of an online GIS database system, hosted by WorldFish, which stores bio-physical, ecological and socio-economic data for the 'Coral Triangle Area' in South-east Asia and the Pacific. The database has been built in partnership with all six (Timor-Leste, Malaysia, Indonesia, The Philippines, Solomon Islands and Papua New Guinea) of the Coral Triangle countries, and represents a valuable source of information for natural resource managers at the regional scale. Its utility is demonstrated using biophysical data, data summarising marine habitats, and data describing the extent of marine protected areas in the region.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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