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  1. Article ; Online: Primary cardiac rhabdomyosarcoma in a mitral valve involved with rheumatic disease.

    Izzat, Mohammad Bashar / Kara Tahhan, Nour / Izzat, Ahmad Walid / Chatty, Eyad M

    Asian cardiovascular & thoracic annals

    2024  Volume 32, Issue 2-3, Page(s) 136–139

    Abstract: A 51-year-old female underwent emergency mitral valve replacement for mitral stenosis with an undetermined mass which was attached to the anterior mitral leaflet. Histopathological testing of the excised specimen confirmed the diagnosis of rheumatic ... ...

    Abstract A 51-year-old female underwent emergency mitral valve replacement for mitral stenosis with an undetermined mass which was attached to the anterior mitral leaflet. Histopathological testing of the excised specimen confirmed the diagnosis of rheumatic mitral disease in combination with a primary rhabdomyosarcoma. Postoperative adjuvant chemotherapy with pazopanib hydrochloride was given. At 10 months of follow-up, repeated computed tomographic screening has not shown any signs of local recurrence or secondary metastases. The potential for the existence of primary rhabdomyosarcomas should be borne in mind when faced with undetermined masses on mitral leaflets, even in the presence of rheumatic disease.
    MeSH term(s) Female ; Humans ; Middle Aged ; Mitral Valve/surgery ; Mitral Valve Insufficiency/surgery ; Rheumatic Heart Disease/surgery ; Mitral Valve Stenosis/surgery ; Heart Neoplasms/pathology ; Rheumatic Diseases/complications ; Rhabdomyosarcoma/complications ; Rhabdomyosarcoma/pathology ; Mediastinal Neoplasms/complications ; Thymus Neoplasms
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1400468-9
    ISSN 1816-5370 ; 0218-4923
    ISSN (online) 1816-5370
    ISSN 0218-4923
    DOI 10.1177/02184923231225991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Successful management strategy for giant primary hepatic rhabdomyosarcoma in 15-year-old male: a case report.

    Brimo Alsaman, Muhamad Zakaria / Ghanem, Roaa / Nahas, Mohamad Ali / Chatty, Eyad M / Hasan, Hasan A / Othman, Zeinab Nabil / Horoub, Rafat

    Journal of surgical case reports

    2024  Volume 2024, Issue 1, Page(s) rjad707

    Abstract: Primary hepatic rhabdomyosarcoma is an exceedingly rare type of sarcomas. A 15-year-old boy was admitted to the hospital with abdominal pain. Serial investigation showed a giant heterogeneous mass, with a diameter of 15 cm, located in the right lobe of ... ...

    Abstract Primary hepatic rhabdomyosarcoma is an exceedingly rare type of sarcomas. A 15-year-old boy was admitted to the hospital with abdominal pain. Serial investigation showed a giant heterogeneous mass, with a diameter of 15 cm, located in the right lobe of the liver (segment 4a, 4b, 5, 6, 7, 8), with clear margins, non-homogeneous density in computerized tomography and the Positron Emission Tomography Scan Multi Slice revealed a peripherally slightly metabolically active hepatic mass (205 × 134 × 208 mm). Histopathological examination and the Immunohistochemical showed embryonal rhabdomyosarcoma. The management strategy involved multiple cycles of ifosfamide and doxorubicin and monitoring the tumor size, until the tumor size was suitable for the surgery. The management of hepatic rhabdomyosarcoma is a surgical challenge due to the late onset of symptoms, a limited number of reported cases, and poor prognosis. Surgical excision is the treatment of choice for primary hepatic rhabdomyosarcoma and combination between chemotherapy, surgery showed good results.
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjad707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Synovial sarcoma of the maxillary sinus - A rare condition managed with a rationalized surgery.

    Hannoun, Burhan / Hannoun, Ibrahim / Bara, Albaraa / Alassaf, Areej / Chatty, Eyad M

    Annals of medicine and surgery (2012)

    2021  Volume 67, Page(s) 102538

    Abstract: Introduction: and importance: Synovial sarcoma is a type of spindle cell tumors with unknown cellular origin. It can present anywhere throughout the body; however, its onset in the maxillary sinus is an extremely rare condition, making it hard to ... ...

    Abstract Introduction: and importance: Synovial sarcoma is a type of spindle cell tumors with unknown cellular origin. It can present anywhere throughout the body; however, its onset in the maxillary sinus is an extremely rare condition, making it hard to diagnose. This tumor occurs equally, without predilection for males or females, and the incidence peaks in the age of 35. The diagnosis is confirmed by histopathological study, and the main treatment is complete surgical excision.
    Case presentation: We are reporting a case of a 53-year-old male with a left sided hearing loss accompanied by a left sided nasal block and a vague facial and dental pain.
    Clinical discussion: Magnetic Resonance Imaging (MRI) showed a heterogeneously enhancing tumor in the maxillary sinus that extended to the pterygopalatine fossa and other surrounding structures, and a biopsy showed the tumor to be a synovial sarcoma. The tumor was managed with a less aggressive curative surgery, and was put on an adjuvant radiotherapy, and is being followed regularly; with no recurrence 5 months after therapy.
    Conclusion: In conclusion, we are writing this report to introduce a case of synovial sarcoma in a rare location that was managed by a "cosmetically oriented" curative surgery, satisfactory results and prognosis.
    Language English
    Publishing date 2021-07-03
    Publishing country England
    Document type Case Reports
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2021.102538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Rhabdomyosarcoma of the uterus with multiple metastases in a post-menopausal woman.

    Alkhaledi, Ahmad / Hanafi, Ibrahem / Alsabe, Hassan / Chatty, Eyad M

    Oxford medical case reports

    2019  Volume 2019, Issue 3, Page(s) omz017

    Abstract: Rhabdomyosarcoma (RMS) is a malignant soft tissue tumor, usually presenting in the head and neck in children, with frequent metastases to the lungs. In this report, we present a rare case of a post-menopausal RMS patient who presented with walking ... ...

    Abstract Rhabdomyosarcoma (RMS) is a malignant soft tissue tumor, usually presenting in the head and neck in children, with frequent metastases to the lungs. In this report, we present a rare case of a post-menopausal RMS patient who presented with walking difficulties after hysterectomy. A computerized tomography scan revealed metastases spreading to the mediastinum, retroperitoneum, lungs, liver and bones. On a protocol of Gemcitabine and Carboplatin, the patient showed stability in the dimensions of the masses with significant improvement in her quality of life.
    Language English
    Publishing date 2019-03-29
    Publishing country England
    Document type Case Reports
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omz017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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