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Article ; Online: A systematic review on multipotent carcinogenic agent, N-nitrosodiethylamine (NDEA), its major risk assessment, and precautions.

Janmeda, Pracheta / Jain, Divya / Chaudhary, Priya / Meena, Mukesh / Singh, Devendra

2024

Abstract: The International Agency for Research on Cancer has classified N-nitrosodiethylamine (NDEA) as a possible carcinogen and mutagenic substances, placing it in category 2A of compounds that are probably harmful to humans. It is found in nature and tobacco ... ...

Abstract	The International Agency for Research on Cancer has classified N-nitrosodiethylamine (NDEA) as a possible carcinogen and mutagenic substances, placing it in category 2A of compounds that are probably harmful to humans. It is found in nature and tobacco smoke, along with its precursors, and is also synthesized endogenously in the human body. The oral or parenteral administration of a minimal quantity of NDEA results in severe liver and kidney organ damage. The NDEA required bioactivation by CYP450 enzyme to form DNA adduct in the alkylation mechanism. Thus, this bioactivation directs oxidative stress and injury to cells due to the higher formation of reactive oxygen species and alters antioxidant system in tissues, whereas free radical scavengers guard the membranes from NDEA-directed injury in many enzymes. This might be one of the reasons in the etiology of cancer that is not limited to a certain target organ but can affect various organs and organ systems. Although there are various possible approaches for the treatment of NDEA-induced cancer, their therapeutic outcomes are still very dismal. However, several precautions were considered to be taken during handling or working with NDEA, as it considered being the best way to lower down the occurrence of NDEA-directed cancers. The present review was designed to enlighten the general guidelines for working with NDEA, possible mechanism, to alter the antioxidant line to cause malignancy in different parts of animal body along with its protective agents. Thus, revelation to constant, unpredictable stress situations even in common life may remarkably augment the toxic potential through the rise in the oxidative stress and damage of DNA.
Language	English
Publishing date	2024-01-11
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	604625-3
ISSN	1099-1263 ; 0260-437X
ISSN (online)	1099-1263
ISSN	0260-437X
DOI	10.1002/jat.4574
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Zs.A 1661: Show issues

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Article ; Online: Microscopic characterization, TLC fingerprinting and optimization of total lipid content from Euphorbia neriifolia (L.) using response surface methodology.

Chaudhary, Priya / Meena, Mukesh / Janmeda, Pracheta

Microscopy research and technique

2023 Volume 87, Issue 3, Page(s) 565–590

Abstract: Euphorbia neriifolia (EN) is a medicinal plant used to treat a variety of ailments in traditional systems. Despite numerous studies on pharmacological activities, no information was available on the microscopic study of this plant. This is the first ... ...

Abstract	Euphorbia neriifolia (EN) is a medicinal plant used to treat a variety of ailments in traditional systems. Despite numerous studies on pharmacological activities, no information was available on the microscopic study of this plant. This is the first study that has been attempted to fill this need by performing the light and field emission scanning electron microscopy (FESEM) of leaf, stem, and latex. The powder microscopy of several organs (leaves, stem, and bark) and exudate (latex) of EN was carried out using safranine, fast green, phloroglucinol, and other standard solutions at different magnifications. The chemical fingerprinting of petroleum ether extract was accomplished by using thin layer chromatography. The optimization of total lipid content from the EN leaf under ultrasound-assisted extraction (UAE) and soxhlet extraction (SE) procedure was determined using response surface methodology (RSM). The studied factors that affect the lipid content were: solvent ratio, extraction temperature, and extraction time. Several notable characteristics observed in the leaf of EN are amphistomatic leaves with anticlinical cell walls, anomocytic stomata, spongy mesophyll cells, elongated palisade cells, angular collenchyma, and U-shaped vascular bundle. The plano-convex midrib is covered by polygonal to oval-shaped cuticles and contains anomocytic stomata. The circular petiole has no trichomes and contains laticifers, crystals, and idioblasts. The circular stem was observed with trichomes, hypodermis, collenchyma, parenchymatous cells, central pith, pentagonal stellar region, cambium, and 2-4 times more xylem that of phloem. All of the powdered plant parts and exudate under study contained trichomes, xylem vessels, wood fibers, cork cells, starch grains, calcium oxalate crystals, idioblasts, lignified cork, tannin content, stone cells, and oil globules. The blackish-green colored petroleum ether extract with semi-solid consistency showed the greatest percent (%) yield of 4% in the latex of EN. The thin layer chromatography (TLC) examination of petroleum ether extract of EN leaf produced a maximum 6 spots with R
MeSH term(s)	Euphorbia ; Chromatography, Thin Layer ; Latex ; Solvents/chemistry ; Plant Extracts/chemistry ; Microscopy, Electron, Scanning ; Lipids ; Alkanes
Chemical Substances	naphtha (O3L624621X) ; Latex ; Solvents ; Plant Extracts ; Lipids ; Alkanes
Language	English
Publishing date	2023-11-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	1099714-3
ISSN	1097-0029 ; 1059-910X
ISSN (online)	1097-0029
ISSN	1059-910X
DOI	10.1002/jemt.24456
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Article ; Online: Etiology of lung carcinoma and treatment through medicinal plants, marine plants and green synthesized nanoparticles: A comprehensive review.

Chaudhary, Priya / Janmeda, Pracheta / Pareek, Aaushi / Chuturgoon, Anil A / Sharma, Rohit / Pareek, Ashutosh

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2024 Volume 173, Page(s) 116294

Abstract: Lung cancer, a leading global cause of mortality, poses a significant public health challenge primarily linked to tobacco use. While tobacco contributes to over 90% of cases, factors like dietary choices and radiation exposure also play a role. Despite ... ...

Abstract	Lung cancer, a leading global cause of mortality, poses a significant public health challenge primarily linked to tobacco use. While tobacco contributes to over 90% of cases, factors like dietary choices and radiation exposure also play a role. Despite potential benefits from early detection, cancer patients face hurdles, including drug resistance, chemotherapy side effects, high treatment costs, and limited healthcare access. Traditional medicinal plant knowledge has recently unveiled diverse cancer chemopreventive agents from terrestrial and marine sources. These phytochemicals regulate intricate molecular processes, influencing the immune system, apoptosis, cell cycle, proliferation, carcinogen elimination, and antioxidant levels. In pursuing cutting-edge strategies to combat the diverse forms of cancer, technological advancements have spurred innovative approaches. Researchers have focused on the green synthesis of metallic nanoparticles using plant metabolites. This method offers distinct advantages over conventional physical and chemical synthesis techniques, such as cost-effectiveness, biocompatibility, and energy efficiency. Metallic nanoparticles, through various pathways such as the generation of reactive oxygen species, modulation of enzyme activity, DNA fragmentation, disruption of signaling pathways, perturbation of cell membranes, and interference with mitochondrial function resulting in DNA damage, cell cycle arrest, and apoptosis, exhibit significant potential for preventive applications. Thus, the amalgamation of phytocompounds and metallic nanoparticles holds promise as a novel approach to lung cancer therapy. However, further refinements and advancements are necessary to enhance the environmentally friendly process of metallic nanoparticle synthesis.
MeSH term(s)	Humans ; Plants, Medicinal/metabolism ; Nanoparticles ; Metal Nanoparticles/chemistry ; Lung Neoplasms/drug therapy ; Lung ; Carcinoma ; Green Chemistry Technology ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Plant Extracts/chemistry
Chemical Substances	Plant Extracts
Language	English
Publishing date	2024-02-23
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	392415-4
ISSN	1950-6007 ; 0753-3322 ; 0300-0893
ISSN (online)	1950-6007
ISSN	0753-3322 ; 0300-0893
DOI	10.1016/j.biopha.2024.116294
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Article ; Online: Removal of emergent pollutants: A review on recent updates and future perspectives on polysaccharide-based composites vis-à-vis traditional adsorbents.

Nayak, Arunima / Chaudhary, Priya / Bhushan, Brij / Ghai, Kapil / Singh, Seema / Sillanpää, Mika

International journal of biological macromolecules

2024 Volume 258, Issue Pt 2, Page(s) 129092

Abstract: There is a growing incidence in the presence of emergent pollutants like the pesticides and pharmaceuticals in water bodies. The matter of environmental concern is their synthetic and persistent nature which has resulted in induced toxicity/damaging ... ...

Abstract	There is a growing incidence in the presence of emergent pollutants like the pesticides and pharmaceuticals in water bodies. The matter of environmental concern is their synthetic and persistent nature which has resulted in induced toxicity/damaging effect to the vital functioning of the different organs in the aquatic community. Traditional adsorbents have exhibited limitations like low stability and minimum reuse ability. Composites of such adsorbents with polysaccharides have demonstrated distinct features like improved surface area, porosity, adsorptivity; improved reusability and structural integrity; improved mechanical strength, thermal stability when applied for the removal of the emergent pollutants. The biocompatibility and biodegradability of such fabricated composites is established; thereby making the water treatment process cost effective, sustainable and environmentally friendly. The present review has dealt with an in-depth, up-dated literature compilation of traditional as well as polysaccharide based composite adsorbents and addressed their performance evaluation for the removal of pharmaceuticals and pesticides from wastewater. A comparative study has revealed the merits of polysaccharide based composites and discussions have been made with a focus on future research directions in the related area.
MeSH term(s)	Adsorption ; Environmental Pollutants ; Pesticides ; Polysaccharides ; Wastewater ; Water Pollutants, Chemical/chemistry ; Water Purification/methods
Chemical Substances	Environmental Pollutants ; Pesticides ; Polysaccharides ; Wastewater ; Water Pollutants, Chemical
Language	English
Publishing date	2024-01-01
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.129092
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Zs.B 2374: Show issues

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Article ; Online: Role of Fungi in Imparting General Disease Suppressiveness in Soil from Organic Field.

Khatri, Shivani / Chaudhary, Priya / Shivay, Yashbir S / Sharma, Shilpi

Microbial ecology

2023 Volume 86, Issue 3, Page(s) 2047–2059

Abstract: Soil microbial communities are key players responsible for imparting suppressive potential to the soil against soil-borne phytopathogens. Fungi have an immense potential to inhibit soil-borne phytopathogens, but the fungal counterpart has been less ... ...

Abstract	Soil microbial communities are key players responsible for imparting suppressive potential to the soil against soil-borne phytopathogens. Fungi have an immense potential to inhibit soil-borne phytopathogens, but the fungal counterpart has been less explored in this context. We assessed the composition of fungal communities in soil under long-term organic and conventional farming practice, and control soil. The disease-suppressive potential of organic field was already established. A comparative analysis of the disease suppressiveness contributed by the fungal component of soil from conventional and organic farms was assessed using dual culture assays. The quantification of biocontrol markers and total fungi was done; the characterization of fungal community was carried out using ITS-based amplicon sequencing. Soil from organic field exhibited higher disease-suppressive potential than that from conventional farming, against the pathogens selected for the study. Higher levels of hydrolytic enzymes such as chitinase and cellulase, and siderophore production were observed in soil from the organic field compared to the conventional field. Differences in community composition were observed under conventional and organic farming, with soil from organic field exhibiting specific enrichment of key biocontrol fungal genera. The fungal alpha diversity was lower in soil from the organic field compared to the conventional field. Our results highlight the role of fungi in contributing to general disease-suppressive ability of the soil against phytopathogens. The identification of fungal taxa specifically associated with organic farming can aid in understanding the mechanism of disease suppression under such a practice, and can be exploited to induce general disease suppressiveness in otherwise conducive soil.
MeSH term(s)	Soil ; Fungi/genetics ; Bacteria ; Agriculture/methods ; Organic Agriculture/methods ; Soil Microbiology
Chemical Substances	Soil
Language	English
Publishing date	2023-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	1462065-0
ISSN	1432-184X ; 0095-3628
ISSN (online)	1432-184X
ISSN	0095-3628
DOI	10.1007/s00248-023-02211-z
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Article: Imaging of Soft-Tissue Pseudotumors: A Pictorial Review

Chaudhary, Priya / Satija, Bhawna / Solanki, RS / Lal, Romesh / Agarwal, Kiran

Indographics

2024 Volume 03, Issue 01, Page(s) 238–245

Abstract: Soft-tissue pseudotumors are a myriad group of clinically palpable masses that mimic soft-tissue tumors. These mimickers may be misinterpreted as malignant sarcomas despite appropriate clinical and radiological evaluation, resulting in unwarranted ... ...

Abstract	Soft-tissue pseudotumors are a myriad group of clinically palpable masses that mimic soft-tissue tumors. These mimickers may be misinterpreted as malignant sarcomas despite appropriate clinical and radiological evaluation, resulting in unwarranted interventions and a diagnosis of a pseudotumors is achieved only after histopathological evaluation. A systematic approach is needed to achieve a definitive diagnosis or to limit the differential diagnosis by using imaging in conjunction with clinical history, physical examination, and anatomical location. The objective of this article is to provide an overview of the imaging features of some of the most common soft-tissue pseudotumors. Recognition of these pseudotumors is of paramount importance as no further investigation or intervention may be required in majority of the cases.
Keywords	pseudotumors ; soft-tissue mass ; tumor mimic
Language	English
Publishing date	2024-01-01
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	2583-8229
ISSN (online)	2583-8229
DOI	10.1055/s-0043-1778081
Database	Thieme publisher's database

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Article ; Online: Antipyretic Medicinal Plants, Phytocompounds, and Green Nanoparticles: An Updated Review.

Chaudhary, Priya / Sharma, Rohit / Rawat, Sonam / Janmeda, Pracheta

Current pharmaceutical biotechnology

2022 Volume 24, Issue 1, Page(s) 23–49

Abstract: Pyrexia itself is not a terminal condition. Basically, it occurs with mild to serious diseases affecting alarge population of the world. Other than a high body temperature, pyrexia is accompanied by several sickness behaviors, changes in physiological ... ...

Abstract	Pyrexia itself is not a terminal condition. Basically, it occurs with mild to serious diseases affecting alarge population of the world. Other than a high body temperature, pyrexia is accompanied by several sickness behaviors, changes in physiological and metabolic characteristics of the body system, and alterations in the immune responses. Various allopathic drugs are available to treat pyrexia by targeting the symptom or the pathogen itself. Drug-resistance has made control and treatment of vectors more difficult. However, many marginal people are obligated to utilize locally available medicinal plants for the treatment of various diseases due to limited access to synthetic drugs. Developments in the field of nanotechnology and phytochemical research towards the discovery of new antimicrobial agents have also drawn the interest of researchers towards the synthesis of green nanoparticles from plant extracts due to their several benefits over the other methods. Thus, the present report discusses the use of ethnomedicinal plants, phytocompounds, and the application of green nanoparticles synthesized from plant extracts to treat pyrexia.
MeSH term(s)	Humans ; Plants, Medicinal/chemistry ; Antipyretics/pharmacology ; Antipyretics/therapeutic use ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Plant Extracts/chemistry ; Nanoparticles ; Fever/drug therapy
Chemical Substances	Antipyretics ; Plant Extracts
Language	English
Publishing date	2022-03-30
Publishing country	Netherlands
Document type	Review ; Journal Article
ZDB-ID	2132197-8
ISSN	1873-4316 ; 1389-2010
ISSN (online)	1873-4316
ISSN	1389-2010
DOI	10.2174/1389201023666220330005020
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Article ; Online: Satellite hyperspectral imaging technology as a potential rapid pollution assessment tool for urban landfill sites: case study of Ghazipur and Okhla landfill sites in Delhi, India.

Dutta, Amitava / Chaudhary, Priya / Sharma, Shilpi / Lall, Brejesh

Environmental science and pollution research international

2022 Volume 30, Issue 55, Page(s) 116742–116750

Abstract: Hyperspectral imaging technology has been used for biochemical analysis of Earth's surface exploiting the spectral reflectance signatures of various materials. The new-generation Italian PRISMA (PRecursore IperSpettrale dellaMissione Applicativa) ... ...

Abstract	Hyperspectral imaging technology has been used for biochemical analysis of Earth's surface exploiting the spectral reflectance signatures of various materials. The new-generation Italian PRISMA (PRecursore IperSpettrale dellaMissione Applicativa) hyperspectral satellite launched by the Italian space agency (ASI) provides a unique opportunity to map various materials through spectral signature analysis for recourse management and sustainable development. In this study PRISMA hyperspectral satellite imagery-based multiple spectral indices were generated for rapid pollution assessment at Ghazipur and Okhla landfill sites in Delhi, India. It was found that the combined risk score for Okhla landfill site was higher than the Ghazipur landfill site. Various manmade materials identified, exploiting the hyperspectral imagery and spectral signature libraries, indicated presence of highly saline water, plastic (black, ABS, pipe, netting, etc.), asphalt tar, black tar paper, kerogen BK-Cornell, black paint and graphite, chalcocite minerals, etc. in large quantities in both the landfill sites. The methodology provides a rapid pollution assessment tool for municipal landfill sites.
MeSH term(s)	Waste Disposal Facilities ; Hyperspectral Imaging ; India ; Satellite Imagery ; Biological Products
Chemical Substances	Biological Products
Language	English
Publishing date	2022-08-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-22421-1
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Article: Assessing the environmental impact of air pollution on crops by monitoring air pollution tolerance index (APTI) and anticipated performance index (API)

Malav, Lal Chand / Kumar, Sandeep / Islam, Sadikul / Chaudhary, Priya / Khan, Shakeel A.

Environmental science and pollution research. 2022 July, v. 29, no. 33

2022

Abstract: Air pollutants adversely affect the physiological, biochemical parameters, and productivity of the crops, but scarce and meager reports are available to know the certain impact of air pollution on crops. The aim of the present study was to assess ... ...

Abstract	Air pollutants adversely affect the physiological, biochemical parameters, and productivity of the crops, but scarce and meager reports are available to know the certain impact of air pollution on crops. The aim of the present study was to assess environmental impact of air pollutants on biochemical parameters of the crops by monitoring two important indicators, i.e., Air Pollution Tolerance Index (APTI) and Anticipated Performance Index (API). These two indicators provide the sensitivity and the tolerance level of the crops towards the air pollutants. Seven different crops were selected in four different locations in the vicinity of a thermal power plant. The results depicted the maximum aerial particulate matter deposition on crop canopy (ADCC) in barley (Hordeum vulgare 2.15 mg/cm²) and wheat (Triticum aestivum 2.21 mg/cm²). The maximum APTI value was found in berseem (Trifolium alexandrinum, 9.45 and 11.44) during the first and second year of study, respectively. Results indicated that all crops were sensitive to air pollution in the selected area, but berseem (Trifolium alexandrinum) was less sensitive in comparison to other crops. API value showed that wheat (Triticum aestivum) and rice (Oryza sativa) were best-suited crops in the selected study area as compared to other crops. It has been found in the study that the API and APTI are two important indicators for the selection of crops in the severe air polluting area.
Keywords	Hordeum vulgare ; Oryza sativa ; Trifolium alexandrinum ; Triticum aestivum ; air ; air pollution ; barley ; canopy ; environmental impact ; particulates ; power plants ; research ; rice ; wheat
Language	English
Dates of publication	2022-07
Size	p. 50427-50442.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-19505-3
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Spreadable Virus of the 21stCentuary

Chaudhary, Priya / Janmeda, Pracheta

Environment Conservation Journal; Vol 21 No 1&; 13-18 ; 2278-5124 ; 0972-3099 ; 10.36953/ECJ.2020.2112

COVID-19

2020 Volume 2, Issue : Environment Conservation Journal

Abstract: The latest outbreak of a respiratory disease, known as coronavirus disease 19 (COVID-19), is the third virus spillover from animals to humans in the last two decades. The disease is caused by coronavirus and has converted into an epidemic in recent days. ...

Abstract	The latest outbreak of a respiratory disease, known as coronavirus disease 19 (COVID-19), is the third virus spillover from animals to humans in the last two decades. The disease is caused by coronavirus and has converted into an epidemic in recent days. It spread via direct contact or droplets of nasal-discharge from one human-to-another within the mean-incubation period of 6.5 days. Dyspnea, cough and fever are the most common symptoms in the patients of COVID-19, though along with diarrhea in 3% cases. Bilateral pulmonary with ground-glass opacity and consolidation has been observed in 98% cases of the disease by the help of computed tomography. The treatment process of COVID-19 with chloroquine and remdesivir drug is under the clinical trial worldwide and responding well to cure the disease. Under the prevalent circumstances, the main goal is to control the widespread infection of SARS-CoV-2 across the world and to aware the public regarding the possible preventive measures and treatments. However, the public health authorities should keep a close eye on the circumstances strictly, as the more we know about this novel coronavirus and its outbreak, the better we can respond or control the conditions worldwide.
Keywords	COVID-19 ; Disease ; Pandemic ; SARS-CoV-2 ; Symptoms ; Treatments ; Virus ; Biotechnology ; covid19
Subject code	630
Language	English
Publishing date	2020-06-09
Publisher	Action for Sustainable Efficacious development and Awareness
Publishing country	in
Document type	Article ; Online
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