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Book ; Online ; E-Book: Assessment of polymeric materials for biomedical applications

Chaudhary, Vijay / Gupta, Sumit, |c Dr / Gupta, Pallav, |c Dr / Das, Partha Pratim

(Emerging Materials and Technologies Series)

2024

Abstract: This book explains various facets of polymeric materials in biomedical filed including overview of various toxicology assessments of polymeric materials, polymeric materials for drug delivery system. Design & analysis of polymeric materials based ... ...

Author's details	edited by Vijay Chaudhary, Sumit Gupta, Pallav Gupta, Partha Pratim Das
Series title	Emerging Materials and Technologies Series
Abstract	This book explains various facets of polymeric materials in biomedical filed including overview of various toxicology assessments of polymeric materials, polymeric materials for drug delivery system. Design & analysis of polymeric materials based components using ANSYS Software alongwith additively manufactured artificial organs is included.
Keywords	Biomedical materials ; Polymers
Language	English
Size	1 online resource (217 pages)
Edition	First edition.
Publisher	CRC Press
Publishing place	Boca Raton, FL
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	9781032333243 ; 1-00-331913-0 ; 1-003-31913-0 ; 1-000-95225-8 ; 1032333243 ; 978-1-00-331913-9 ; 978-1-003-31913-9 ; 978-1-000-95225-4
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: An Interesting Case of Refractory Thrombotic Thrombocytopenic Purpura in the First Trimester of a Twin Pregnancy.

Jacob, Giuseppina / Dhaliwal, Amanpreet / Chaudhary, Vijay

Cureus

2023 Volume 15, Issue 10, Page(s) e47153

Abstract: Thrombotic thrombocytopenic purpura (TTP) is a rare pregnancy complication characterized by microangiopathic hemolytic anemia and consumption thrombocytopenia. We herein describe the case report of a 32-year-old woman who was six weeks pregnant with ... ...

Abstract	Thrombotic thrombocytopenic purpura (TTP) is a rare pregnancy complication characterized by microangiopathic hemolytic anemia and consumption thrombocytopenia. We herein describe the case report of a 32-year-old woman who was six weeks pregnant with twins and developed thrombotic thrombocytic purpura (TTP). The patient had a history of sickle cell trait, migraines, and preeclampsia. She presented with complaints of nausea, fatigue, sore throat, and cough and was found to be anemic with a hemoglobin of 7 g/dl and thrombocytopenic with a platelet count of 8 x 10
Language	English
Publishing date	2023-10-16
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.47153
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Au-TiO

Chaudhary, Vijay Shanker / Kumar, Dharmendra / Kumar, Santosh

IEEE transactions on nanobioscience

2023 Volume 22, Issue 3, Page(s) 562–569

Abstract: A surface plasmon resonance (SPR) refractometric sensor based on gold (Au) and titanium dioxide ( ... ...

Abstract	A surface plasmon resonance (SPR) refractometric sensor based on gold (Au) and titanium dioxide (TiO
MeSH term(s)	Humans ; Female ; Surface Plasmon Resonance ; Gold ; HeLa Cells ; Breast Neoplasms
Chemical Substances	titanium dioxide (15FIX9V2JP) ; Gold (7440-57-5)
Language	English
Publishing date	2023-06-29
Publishing country	United States
Document type	Journal Article
ISSN	1558-2639
ISSN (online)	1558-2639
DOI	10.1109/TNB.2022.3219104
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Article ; Online: How do root fungi of Alnus nepalensis and Schima wallichii recover during succession of abandoned land?

Balami, Sujan / Vašutová, Martina / Chaudhary, Vijay Kumar / Cudlín, Pavel

Mycorrhiza

2023 Volume 33, Issue 5-6, Page(s) 321–332

Abstract: Alnus nepalensis and Schima wallichii are native tree species accompanying succession in abandoned agricultural land in the middle mountainous region of central Nepal. To understand how root fungi recover during spontaneous succession, we analyzed the ... ...

Abstract	Alnus nepalensis and Schima wallichii are native tree species accompanying succession in abandoned agricultural land in the middle mountainous region of central Nepal. To understand how root fungi recover during spontaneous succession, we analyzed the diversity and composition of arbuscular mycorrhizal (AM), ectomycorrhizal (ECM), and total fungi in tree fine roots from three land use types, short-term abandoned land (SA), long-term abandoned land (LA), and regenerated forest (RF) as a reference. Additionally, ECM morphotypes were examined. The results showed different speeds of succession in the studied fungal groups. While the change in the AM fungal community appears to be rapid and LA resembles the composition of RF, the total fungi in the abandoned land types are similar to each other but differed significantly from RF. Interestingly, the relative abundance of Archaeosporaceae followed a trend differing between the tree species (SA < LA in A. nepalensis, but SA > LA in S. wallichii). Unlike AM and total fungi, there was no significant difference in the ECM community of A. nepalensis between land use types, probably due to their low species diversity (9 ECM morphotypes, 31 ECM operational taxonomic units). However, Cortinarius sp. was significantly more abundant in RF than in the other land use types, whereas Alnicola, Tomentella, and Russula preferred young stages. Our results suggest that for both studied tree species the AM fungal succession could reach the stage of regenerated forest relatively fast. In the case of total fungi, because of hyperdiversity and composed of species specialized to a variety of environments and substrates, the transition was expected to be delayed in abandoned land where the vegetation was still developing and the ecosystem was not as complex as that found in mature forests.
MeSH term(s)	Mycorrhizae ; Alnus ; Soil Microbiology ; Forests ; Ecosystem ; Trees/microbiology ; Agaricales ; Soil ; Fungi
Chemical Substances	Soil
Language	English
Publishing date	2023-09-13
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1087945-6
ISSN	1432-1890 ; 0940-6360
ISSN (online)	1432-1890
ISSN	0940-6360
DOI	10.1007/s00572-023-01124-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Sustainable Polysaccharide Hydrogels Based on Dynamic Schiff Base Linkages as Versatile Building Blocks for Fabricating Advanced Functional Materials

Shekhar, Shashank / Chaudhary, Vijay / Sharma, Bhasha / Kumar, Amit / Bhagi, Ajay Kumar / Singh, Kiran Pal

J Polym Environ. 2023 Apr., v. 31, no. 4 p.1257-1278

2023

Abstract: Polysaccharides are an idiosyncratic source of organic natural materials apropos structural diversity, functionalities, and abundance. In their indigenous state, few of their functionalities inhabit their material form as hydrogels, consequently ... ...

Abstract	Polysaccharides are an idiosyncratic source of organic natural materials apropos structural diversity, functionalities, and abundance. In their indigenous state, few of their functionalities inhabit their material form as hydrogels, consequently proffering molecular tactics to be exploited. Recently, polysaccharide-based hydrogels utilizing the Schiff base bonds or dynamic imine chemistry as crosslinks have been widely explored owing to their high sensitivity, good flexibility, enhanced recyclability, stimuli-responsiveness, and tissue adhesion. The polysaccharide-derived Schiff base hydrogels bestow elementary fabrication, self-healing properties, and injectibility under physiological conditions, resulting in mechanical forces that result in the augmentation of gel precursors. These hierarchical constructs can be tuned for mechanically, morphologically, and biochemically different microenvironments, thus finding numerous applications in a variety of fields. Herein, we comprehensively analyze the constitutive nature, state-of-the-art design principles, gelling mechanism, and structural or mechanical properties of dynamic polysaccharide-Schiff-based hydrogels. In a dynamic covalent bond polysaccharide framework, various interactions such as hydrogen bonding, hydrophobic interactions, and metal–ligand interactions produce toughness, high strength, and environmental responsiveness. We propound that polysaccharide hydrogels based on dynamic Schiff base linkages proffer advantages owing to the dynamic interfacial imine formation that can translate changes in bonding to macroscopic outputs. Emerging strategies that may enhance and ameliorate the properties, current scope and functionalities along with current challenges to the field have been assessed to impart guidelines for the rational design of these dynamic hydrogel systems.
Keywords	adhesion ; chemical bonding ; crosslinking ; hydrogels ; hydrogen ; hydrophobicity ; imines ; polysaccharides ; schiff bases
Language	English
Dates of publication	2023-04
Size	p. 1257-1278.
Publishing place	Springer US
Document type	Article ; Online
Note	Review
ZDB-ID	2017207-2
ISSN	1572-8919 ; 1572-8900 ; 1566-2543
ISSN (online)	1572-8919 ; 1572-8900
ISSN	1566-2543
DOI	10.1007/s10924-022-02685-x
Database	NAL-Catalogue (AGRICOLA)

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Article: Timing of Surgery and Pre-operative Physiological Parameters as Clinical Predictors of Surgical Outcomes in Traumatic Subaxial Cervical Spine Fractures and Dislocations.

Khanna, Aman / Menon, Hari / Chaudhary, Vijay / Sidhdhapuria, Pratik / Patel, Kandarp / Narang, Chandan

Revista brasileira de ortopedia

2023 Volume 58, Issue 4, Page(s) e586–e591

Abstract: ... ...

Abstract	Objective
Language	English
Publishing date	2023-08-30
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2411301-3
ISSN	1982-4378 ; 0102-3616
ISSN (online)	1982-4378
ISSN	0102-3616
DOI	10.1055/s-0043-1772240
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Emulsion PCR made easy.

Verma, Vaishali / Gupta, Amita / Chaudhary, Vijay K

BioTechniques

2020 Volume 69, Issue 1, Page(s) 421–426

Abstract: Emulsion PCR (ePCR) is an important technique that permits amplification of DNA molecules in physically separated picoliter-volume water-in-oil droplets, and thus avoids formation of unproductive chimeras and other artifacts between similar DNA sequences. ...

Abstract	Emulsion PCR (ePCR) is an important technique that permits amplification of DNA molecules in physically separated picoliter-volume water-in-oil droplets, and thus avoids formation of unproductive chimeras and other artifacts between similar DNA sequences. However, the recovery of ePCR products involves repeated extraction with hazardous organic solvents followed by purification using silica-based columns, making the overall process cumbersome. In this benchmark, we have described a quick ePCR extraction protocol for the purification of ePCR products, which directly employs silica-based DNA purification columns; products purified using this method have been found to be compatible with gene cloning and next-generation sequencing applications. The method described here makes ePCR easy, safe and within the reach of every laboratory.
Language	English
Publishing date	2020-04-27
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	48453-2
ISSN	1940-9818 ; 0736-6205
ISSN (online)	1940-9818
ISSN	0736-6205
DOI	10.2144/btn-2019-0161
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Isolated Myeloid Sarcoma: A Diagnostic Dilemma.

Aslam, Hafiz M / Veeraballi, Sindhusha / Saeed, Zabila / Weil, Andrew / Chaudhary, Vijay

Cureus

2022 Volume 14, Issue 1, Page(s) e21200

Abstract: Myeloid sarcoma (MS)/granulocytic sarcoma/myeloblastoma/chloroma is a rare extramedullary proliferation of blast cells of one or more myeloid lineages along with the destruction of the normal architecture of adjacent tissue. Isolated MS is a rare entity ... ...

Abstract	Myeloid sarcoma (MS)/granulocytic sarcoma/myeloblastoma/chloroma is a rare extramedullary proliferation of blast cells of one or more myeloid lineages along with the destruction of the normal architecture of adjacent tissue. Isolated MS is a rare entity with an incidence of 0.7 out of 1 million children and 2 out of 1 million adults. Varied clinical presentation, the rarity of the diagnosis, inadequate immunophenotyping, and lack of available literature makes the disease difficult to manage. Here, we report a case of MS in a 44-year-old male with an initial presentation of testicular mass without bone marrow involvement, causing diagnostic challenges. In this case report, we discuss the pathogenesis, diagnostic challenges, and therapeutic options of MS.
Language	English
Publishing date	2022-01-13
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.21200
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Momento da cirurgia e parâmetros fisiológicos pré-operatórios como fatores preditivos clínicos de desfechos cirúrgicos em fraturas e luxações traumáticas subaxiais da coluna cervical

Khanna, Aman / Menon, Hari / Chaudhary, Vijay / Sidhdhapuria, Pratik / Patel, Kandarp / Narang, Chandan

Revista Brasileira de Ortopedia

2023 Volume 58, Issue 04, Page(s) e586–e591

Abstract: Objetivo: Avaliar os fatores de risco e os desfechos em indivíduos submetidos ao tratamento cirúrgico de lesões subaxiais da coluna cervical em relação ao momento da cirurgia e aos parâmetros fisiológicos pré-operatórios dos pacientes.: Métodos: O ... ...

Abstract	Objetivo: Avaliar os fatores de risco e os desfechos em indivíduos submetidos ao tratamento cirúrgico de lesões subaxiais da coluna cervical em relação ao momento da cirurgia e aos parâmetros fisiológicos pré-operatórios dos pacientes. Métodos: O estudo incluiu 26 pacientes com fraturas e luxações subaxiais da coluna cervical. Dados demográficos, investigação radiológica apropriada e parâmetros fisiológicos, como frequência respiratória, pressão arterial, frequência cardíaca, pressão parcial de oxigênio (PaO 2 ) e escalas de disfunção da American Spine Injury Association (ASIA), foram documentados. No período pré-operatório, os pacientes foram divididos em dois grupos. O grupo instável (I) continha pacientes com parâmetros fisiológicos anormais e o grupo estável (E) era composto por pacientes com parâmetros fisiológicos dentro da faixa de normalidade. Os pacientes foram ainda subdivididos em grupos de tratamento precoce e tardio de acordo com o momento da cirurgia como I precoce, I tardio, E precoce e E tardio. Todos os pacientes foram chamados para consultas de acompanhamento em 1, 6 e 12 meses. Resultados: Cinquenta e seis por cento dos pacientes do grupo E apresentaram melhora neurológica em um grau ASIA e desfecho bom independentemente do momento da cirurgia. Os desfechos em pacientes do grupo I com parâmetros fisiológicos instáveis e submetidos à intervenção cirúrgica precoce foram maus. Conclusão: Este estudo conclui que a intervenção cirúrgica precoce em pacientes com instabilidade fisiológica teve forte associação como fator de risco no desfecho final em termos de mortalidade e morbidade. Além disso, não foi possível estabelecer nenhuma associação positiva de melhora em pacientes com estabilidade fisiológica em relação ao momento da cirurgia. ; Objective: To evaluate the risk factors and outcomes in patients surgically treated for subaxial cervical spine injuries with respect of the timing of surgery and preoperative physiological parameters of the patient. Methods: 26 patients with sub-axial cervical spine fractures and dislocations were enrolled. Demographic data of patients, appropriate radiological investigation, and physiological parameters like respiratory rate, blood pressure, heart rate, PaO2 and ASIA impairment scale were documented. They were divided pre-operatively into 2 groups. Group U with patients having abnormal physiological parameters and Group S including patients having physiological parameters within normal range. They were further subdivided into early and late groups according to the timing of surgery as U early, U late, S early and S late. All the patients were called for follow-up at 1, 6 and 12 months. Results: 56 percent of patients in Group S had neurological improvement by one ASIA grade and a good outcome irrespective of the timing of surgery. Patients in Group U having unstable physiological parameters and undergoing early surgical intervention had poor outcomes. Conclusion: This study concludes that early surgical intervention in physiologically unstable patients had a strong association as a risk factor in the final outcome of the patients in terms of mortality and morbidity. Also, no positive association of improvement in physiologically stable patients with respect to the timing of surgery could be established.
Keywords	vértebras cervicais ; duração da cirurgia ; fatores de risco ; estudos prospectivos ; cervical vertebrae ; operative time ; risk factors ; prospective studies
Language	Portuguese
Publishing date	2023-08-01
Publisher	Thieme Revinter Publicações Ltda.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2411301-3
ISSN	1982-4378 ; 0102-3616 ; 1982-4378
ISSN (online)	1982-4378
ISSN	0102-3616 ; 1982-4378
DOI	10.1055/s-0043-1772240
Database	Thieme publisher's database

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Article ; Online: An efficient ORF selection system for DNA fragment libraries based on split beta-lactamase complementation.

Verma, Vaishali / Joshi, Gopal / Gupta, Amita / Chaudhary, Vijay K

PloS one

2020 Volume 15, Issue 7, Page(s) e0235853

Abstract: PCR-based amplification of annotated genes has allowed construction of expression clones at genome-scale using classical and recombination-based cloning technologies. However, genome-scale expression and purification of proteins for down-stream ... ...

Abstract	PCR-based amplification of annotated genes has allowed construction of expression clones at genome-scale using classical and recombination-based cloning technologies. However, genome-scale expression and purification of proteins for down-stream applications is often limited by challenges such as poor expression, low solubility, large size of multi-domain proteins, etc. Alternatively, DNA fragment libraries in expression vectors can serve as the source of protein fragments with each fragment encompassing a function of its whole protein counterpart. However, the random DNA fragmentation and cloning result in only 1 out of 18 clones being in the correct open-reading frame (ORF), thus, reducing the overall efficiency of the system. This necessitates the selection of correct ORF before expressing the protein fragments. This paper describes a highly efficient ORF selection system for DNA fragment libraries, which is based on split beta-lactamase protein fragment complementation. The system has been designed to allow seamless transfer of selected DNA fragment libraries into any downstream vector systems using a restriction enzyme-free cloning strategy. The strategy has been applied for the selection of ORF using model constructs to show near 100% selection of the clone encoding correct ORF. The system has been further validated by construction of an ORF-selected DNA fragment library of 30 genes of M. tuberculosis. Further, we have successfully demonstrated the cytosolic expression of ORF-selected protein fragments in E. coli.
MeSH term(s)	Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cloning, Molecular/methods ; Escherichia coli ; Gene Library ; Genetic Complementation Test/methods ; Mycobacterium tuberculosis ; Open Reading Frames ; beta-Lactamases/genetics ; beta-Lactamases/metabolism
Chemical Substances	Bacterial Proteins ; beta-Lactamases (EC 3.5.2.6)
Language	English
Publishing date	2020-07-23
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0235853
Database	MEDical Literature Analysis and Retrieval System OnLINE

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