Article ; Online: Surface plasmon biosensor based on Bi
Applied optics
2022 Volume 61, Issue 13, Page(s) 3711–3719
Abstract: This theoretical investigation proposes the preliminary stage detection of cancer cells using a prism-based surface plasmon resonance biosensor. The surface plasmon resonance (SPR) biosensor is label-free and rapid; it supports real-time investigations, ... ...
| Abstract | This theoretical investigation proposes the preliminary stage detection of cancer cells using a prism-based surface plasmon resonance biosensor. The surface plasmon resonance (SPR) biosensor is label-free and rapid; it supports real-time investigations, including greater sensitivity, and it has an enormous possibility for detecting different forms of cancer. The refractive index alteration of cancer cells is 1.360-1.401. The performance of the SPR sensor has been analyzed. The different types of cancer cells for skin, cervical, blood, adrenal, and breast (type I and II) have been analyzed, and sensitivities of 292, 384, 229, 242, 254, and 261 (degree/RIU) have been achieved, respectively. A high figure of merit of 115.2 |
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| MeSH term(s) | Humans ; HeLa Cells ; Surface Plasmon Resonance ; Biosensing Techniques ; Refractometry ; Neoplasms/diagnosis |
| Language | English |
| Publishing date | 2022-10-03 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 1539-4522 |
| ISSN (online) | 1539-4522 |
| DOI | 10.1364/AO.454789 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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