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  1. Article ; Online: ChatGPT's Performance in Cardiac Arrest and Bradycardia Simulations Using the American Heart Association's Advanced Cardiovascular Life Support Guidelines: Exploratory Study.

    Pham, Cecilia / Govender, Romi / Tehami, Salik / Chavez, Summer / Adepoju, Omolola E / Liaw, Winston

    Journal of medical Internet research

    2024  Volume 26, Page(s) e55037

    Abstract: Background: ChatGPT is the most advanced large language model to date, with prior iterations having passed medical licensing examinations, providing clinical decision support, and improved diagnostics. Although limited, past studies of ChatGPT's ... ...

    Abstract Background: ChatGPT is the most advanced large language model to date, with prior iterations having passed medical licensing examinations, providing clinical decision support, and improved diagnostics. Although limited, past studies of ChatGPT's performance found that artificial intelligence could pass the American Heart Association's advanced cardiovascular life support (ACLS) examinations with modifications. ChatGPT's accuracy has not been studied in more complex clinical scenarios. As heart disease and cardiac arrest remain leading causes of morbidity and mortality in the United States, finding technologies that help increase adherence to ACLS algorithms, which improves survival outcomes, is critical.
    Objective: This study aims to examine the accuracy of ChatGPT in following ACLS guidelines for bradycardia and cardiac arrest.
    Methods: We evaluated the accuracy of ChatGPT's responses to 2 simulations based on the 2020 American Heart Association ACLS guidelines with 3 primary outcomes of interest: the mean individual step accuracy, the accuracy score per simulation attempt, and the accuracy score for each algorithm. For each simulation step, ChatGPT was scored for correctness (1 point) or incorrectness (0 points). Each simulation was conducted 20 times.
    Results: ChatGPT's median accuracy for each step was 85% (IQR 40%-100%) for cardiac arrest and 30% (IQR 13%-81%) for bradycardia. ChatGPT's median accuracy over 20 simulation attempts for cardiac arrest was 69% (IQR 67%-74%) and for bradycardia was 42% (IQR 33%-50%). We found that ChatGPT's outputs varied despite consistent input, the same actions were persistently missed, repetitive overemphasis hindered guidance, and erroneous medication information was presented.
    Conclusions: This study highlights the need for consistent and reliable guidance to prevent potential medical errors and optimize the application of ChatGPT to enhance its reliability and effectiveness in clinical practice.
    MeSH term(s) Humans ; Bradycardia ; Heart Arrest/therapy ; American Heart Association ; United States ; Advanced Cardiac Life Support/methods ; Algorithms ; Practice Guidelines as Topic
    Language English
    Publishing date 2024-04-22
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/55037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Hazards of Using ChatGPT: A Call to Action for Medical Education Researchers.

    Liaw, Winston / Chavez, Summer / Pham, Cecilia / Tehami, Salik / Govender, Romi

    PRiMER (Leawood, Kan.)

    2023  Volume 7, Page(s) 27

    Language English
    Publishing date 2023-08-21
    Publishing country United States
    Document type Journal Article
    ISSN 2575-7873
    ISSN (online) 2575-7873
    DOI 10.22454/PRiMER.2023.295710
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  3. Article: Pediatric firearm injury epidemiology at a level 1 trauma center from 2019 to 2021: including time of the COVID-19 pandemic.

    Orantes, Cynthia / Chan, Hei Kit / Walter, Daniel / Chavez, Summer / Ugalde, Irma T

    Injury epidemiology

    2023  Volume 10, Issue Suppl 1, Page(s) 41

    Abstract: Background: Firearms are a leading cause of death in children. The demand for firearms increased following COVID-19 "stay-at home orders" in March 2020, resulting in record-breaking firearm sales and background checks. We aim to describe the changes in ... ...

    Abstract Background: Firearms are a leading cause of death in children. The demand for firearms increased following COVID-19 "stay-at home orders" in March 2020, resulting in record-breaking firearm sales and background checks. We aim to describe the changes in pediatric firearm-related injuries, demographics, and associated risk factors at a Level 1 trauma center in Houston before and during the COVID 19 pandemic.
    Results: The total number of pediatric firearm-related injury cases increased during March 15th to December 31st, 2020 and 2021 compared to the same time period in 2019 (104 verses 89 verses 78). The demographic group most affected across years were males (87% in 2019 vs 82% in 2020 and 87% in 2021) between 14 and 17 years old (83% in 2019 vs 81% in 2020 and 76% in 2021). There was an increase in firearm injuries among black youth across all years (28% in 2019 vs 41% in 2020 vs 49% in 2021). Injuries in those with mental illness (10% in 2019 vs 24% in 2020 vs 17% in 2021), and injuries where the shooter was a known family member or friend (14% in 2019 vs 18% in 2020 vs. 15% in 2021), increased from 2019 to 2020.
    Conclusion: The total number of pediatric firearm-related injuries increased during the COVID-19 pandemic compared to the previous year despite a decline in overall pediatric emergency department visits. Increases in pediatric firearm-related injuries in already vulnerable populations should prompt further hospital initiatives including counseling on safe firearm storage, implementation of processes to identify children at risk for firearm injuries, and continued research to mitigate the risk of injury and death associated with firearms in our community.
    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2764253-7
    ISSN 2197-1714
    ISSN 2197-1714
    DOI 10.1186/s40621-023-00448-3
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  4. Article ; Online: Updated estimates of sepsis hospitalizations at United States academic medical centers.

    Chan, Hei Kit / Khose, Swapnil / Chavez, Summer / Patel, Bela / Wang, Henry E

    Journal of the American College of Emergency Physicians open

    2022  Volume 3, Issue 4, Page(s) e12782

    Abstract: Objective: Sepsis is a major public health problem. Understanding the epidemiology of sepsis subtypes is important to quantify the magnitude of the problem and identify targets for system wide treatment strategies. We sought to describe the current ... ...

    Abstract Objective: Sepsis is a major public health problem. Understanding the epidemiology of sepsis subtypes is important to quantify the magnitude of the problem and identify targets for system wide treatment strategies. We sought to describe the current national epidemiology of community-acquired (CAS), hospital-acquired (HAS) and healthcare-associated sepsis (HCAS) hospitalizations among academic medical centers in the United States using current discharge diagnosis taxonomies.
    Methods: Retrospective analysis of patient discharge data from the Vizient Clinical Data Base/Resource Manager. We identified sepsis hospitalizations using four ICD-10 coding strategies: (1) "Martin" sepsis codes (21 ICD-10 codes), (2) "Angus" sepsis codes (ICD-10 infection + ICD-10 organ dysfunction), (3) Medicare "SEP-1" codes (28 ICD-10 codes), and (4) "explicit sepsis" codes (ICD-10 R65.20 and R65.21). Using present-on-admission flags for each diagnosis, we also distinguished: (1) community-acquired sepsis (CAS), (2) hospital-acquired sepsis (HAS), and (3) healthcare associated sepsis (HCAS).
    Results: Among 22,655,240 hospitalizations, the number and incidence of sepsis hospitalizations were: (1) Martin (n = 1,718,257, 75.8 per 1000 hospitalizations), (2) Angus (n = 2,749,163, 121.3 per 1000), (3) SEP-1 (n = 1,624,909, 71.7 per 1000), and (4) explicit sepsis (n = 655,853, 28.9 per 1000). CAS was the most common sepsis subtype. HAS exhibited higher adjusted mortality than CAS. ICU admission was highest for HAS (Martin, 1.5%; Angus, 1.5%; SEP-1, 1.6%; Explicit, 1.9%).
    Conclusions: These results illustrate the prevalence of sepsis at US academic medical centers using the most current sepsis classification taxonomies and discharge diagnosis codes. These results highlight important considerations when using hospital discharge data to characterize the epidemiology of sepsis.
    Language English
    Publishing date 2022-07-16
    Publishing country United States
    Document type Journal Article
    ISSN 2688-1152
    ISSN (online) 2688-1152
    DOI 10.1002/emp2.12782
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  5. Article ; Online: Further considerations regarding lipid emulsion for LAST.

    Montrief, Tim / Chavez, Summer / Gottlieb, Michael / Brady, William J / Long, Brit

    The American journal of emergency medicine

    2022  Volume 59, Page(s) 170–171

    MeSH term(s) Anesthetics, Local ; Fat Emulsions, Intravenous/therapeutic use ; Humans ; Lipids
    Chemical Substances Anesthetics, Local ; Fat Emulsions, Intravenous ; Lipids
    Language English
    Publishing date 2022-07-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2022.07.027
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  6. Article ; Online: Local anesthetic systemic toxicity: A narrative review for emergency clinicians.

    Long, Brit / Chavez, Summer / Gottlieb, Michael / Montrief, Tim / Brady, William J

    The American journal of emergency medicine

    2022  Volume 59, Page(s) 42–48

    Abstract: Introduction: Emergency clinicians utilize local anesthetics for a variety of procedures in the emergency department (ED) setting. Local anesthetic systemic toxicity (LAST) is a potentially deadly complication.: Objective: This narrative review ... ...

    Abstract Introduction: Emergency clinicians utilize local anesthetics for a variety of procedures in the emergency department (ED) setting. Local anesthetic systemic toxicity (LAST) is a potentially deadly complication.
    Objective: This narrative review provides emergency clinicians with the most current evidence regarding the pathophysiology, evaluation, and management of patients with LAST.
    Discussion: LAST is an uncommon but potentially life-threatening complication of local anesthetic use that may be encountered in the ED. Patients at extremes of age or with organ dysfunction are at higher risk. Inadvertent intra-arterial or intravenous injection, as well as repeated doses and higher doses of local anesthetics are associated with greater risk of developing LAST. Neurologic and cardiovascular manifestations can occur. Early recognition and intervention, including supportive care and intravenous lipid emulsion 20%, are the mainstays of treatment. Using ultrasound guidance, aspirating prior to injection, and utilizing the minimal local anesthetic dose needed are techniques that can reduce the risk of LAST.
    Conclusions: This focused review provides an update for the emergency clinician to manage patients with LAST.
    MeSH term(s) Anesthesia, Local ; Anesthetics, Local/adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Fat Emulsions, Intravenous/therapeutic use ; Humans ; Injections
    Chemical Substances Anesthetics, Local ; Fat Emulsions, Intravenous
    Language English
    Publishing date 2022-06-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2022.06.017
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  7. Article ; Online: Malaria: A focused review for the emergency medicine clinician.

    Long, Brit / MacDonald, Austin / Liang, Stephen Y / Brady, William J / Koyfman, Alex / Gottlieb, Michael / Chavez, Summer

    The American journal of emergency medicine

    2023  Volume 77, Page(s) 7–16

    Abstract: Introduction: Malaria is a potentially fatal parasitic disease transmitted by the Anopheles mosquito. A resurgence in locally acquired infections has been reported in the U.S.: Objective: This narrative review provides a focused overview of malaria ... ...

    Abstract Introduction: Malaria is a potentially fatal parasitic disease transmitted by the Anopheles mosquito. A resurgence in locally acquired infections has been reported in the U.S.
    Objective: This narrative review provides a focused overview of malaria for the emergency clinician, including the epidemiology, presentation, diagnosis, and management of the disease.
    Discussion: Malaria is caused by Plasmodium and is transmitted by the Anopheles mosquito. Disease severity can range from mild to severe. Malaria should be considered in any returning traveler from an endemic region, as well as those with unexplained cyclical, paroxysms of symptoms or unexplained fever. Patients most commonly present with fever and rigors but may also experience cough, myalgias, abdominal pain, fatigue, vomiting, and diarrhea. Hepatomegaly, splenomegaly, pallor, and jaundice are findings associated with malaria. Although less common, severe malaria is precipitated by microvascular obstruction with complications of anemia, acidosis, hypoglycemia, multiorgan failure, and cerebral malaria. Peripheral blood smears remain the gold standard for diagnosis, but rapid diagnostic tests are available. Treatment includes specialist consultation and antimalarial drugs tailored depending on chloroquine resistance, geographic region of travel, and patient comorbidities. Supportive care may be required, and patients with severe malaria will require resuscitation. Most patients will require admission for treatment and further monitoring.
    Conclusion: Emergency medicine clinicians should be aware of the presentation, diagnosis, evaluation, and management of malaria to ensure optimal outcomes.
    MeSH term(s) Animals ; Humans ; Antimalarials/therapeutic use ; Plasmodium ; Chloroquine ; Travel ; Malaria, Cerebral/drug therapy ; Fever/drug therapy
    Chemical Substances Antimalarials ; Chloroquine (886U3H6UFF)
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2023.11.035
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  8. Article ; Online: Ebola virus disease: A review for the emergency medicine clinician.

    Chavez, Summer / Koyfman, Alex / Gottlieb, Michael / Brady, William J / Carius, Brandon M / Liang, Stephen Y / Long, Brit

    The American journal of emergency medicine

    2023  Volume 70, Page(s) 30–40

    Abstract: Introduction: Ebolavirus, the causative agent of Ebola virus disease (EVD) has been responsible for sporadic outbreaks mainly in sub-Saharan Africa since 1976. EVD is associated with high risk of transmission, especially to healthcare workers during ... ...

    Abstract Introduction: Ebolavirus, the causative agent of Ebola virus disease (EVD) has been responsible for sporadic outbreaks mainly in sub-Saharan Africa since 1976. EVD is associated with high risk of transmission, especially to healthcare workers during patient care.
    Objective: The purpose of this review is to provide a concise review of EVD presentation, diagnosis, and management for emergency clinicians.
    Discussion: EVD is spread through direct contact, including blood, bodily fluids or contact with a contaminated object. Patients may present with non-specific symptoms such as fevers, myalgias, vomiting, or diarrhea that overlap with other viral illnesses, but rash, bruising, and bleeding may also occur. Laboratory analysis may reveal transaminitis, coagulopathy, and disseminated intravascular coagulation. The average clinical course is approximately 8-10 days with an average case fatality rate of 50%. The mainstay of treatment is supportive care, with two U.S. Food and Drug Administration-approved monoclonal antibody treatments (Ebanga and Inmazeb). Survivors of the disease may have a complicated recovery, marked by long-term symptoms.
    Conclusion: EVD is a potentially deadly condition that can present with a wide range of signs and symptoms. Emergency clinicians must be aware of the presentation, evaluation, and management to optimize the care of these patients.
    MeSH term(s) Humans ; Hemorrhagic Fever, Ebola/diagnosis ; Hemorrhagic Fever, Ebola/epidemiology ; Hemorrhagic Fever, Ebola/therapy ; Ebolavirus ; Hemorrhage/epidemiology ; Fever/epidemiology ; Disease Outbreaks ; Emergency Medicine
    Language English
    Publishing date 2023-04-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2023.04.037
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  9. Article ; Online: Response from the authors: Advanced ventilation strategies in patients with Fontan-type circulation.

    Chavez, Summer / Brady, William J / Gottlieb, Michael / Carius, Brandon M / Liang, Stephen Y / Koyfman, Alex / Long, Brit

    The American journal of emergency medicine

    2023  Volume 66, Page(s) 155–156

    MeSH term(s) Humans ; Fontan Procedure ; Pulmonary Ventilation
    Language English
    Publishing date 2023-01-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2023.01.011
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  10. Article ; Online: Mimics of Monkeypox: Considerations for the emergency medicine clinician.

    Long, Brit / Liang, Stephen Y / Carius, Brandon M / Chavez, Summer / Gottlieb, Michael / Koyfman, Alex / Brady, William J

    The American journal of emergency medicine

    2023  Volume 65, Page(s) 172–178

    Abstract: Introduction: Mpox, formerly known as monkeypox, is a public health emergency most commonly presenting with a painful rash and several systemic findings. However, there are several conditions that may mimic its presentation.: Objective: This ... ...

    Abstract Introduction: Mpox, formerly known as monkeypox, is a public health emergency most commonly presenting with a painful rash and several systemic findings. However, there are several conditions that may mimic its presentation.
    Objective: This narrative review provides a focused overview of mpox mimics for emergency clinicians.
    Discussion: Mpox is a global health emergency. The disease is primarily spread through contact, followed by the development of a centrifugally-spread rash that evolves from macules to papules to vesicles to pustules. This is often associated with lymphadenopathy and fever. As the rash is one of the most common presenting signs of the infection, patients mpox may present to the emergency department (ED) for further evaluation. There are a variety of mimics of mpox, including smallpox, varicella, primary and secondary syphilis, acute retroviral syndrome, and genital herpes simplex virus.
    Conclusion: Knowledge of mpox and its mimics is vital for emergency clinicians to differentiate these conditions and ensure appropriate diagnosis and management.
    MeSH term(s) Humans ; Mpox (monkeypox) ; Exanthema ; Emergency Medicine ; Emergency Service, Hospital ; Fever
    Language English
    Publishing date 2023-01-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2023.01.007
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