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  1. Book: Facilitating treatment adherence in pain medicine

    Cheatle, Martin D. / Fine, Perry G.

    2017  

    Author's details edited by Martin D. Cheatle, Perry G. Fine
    Keywords Pain Management / psychology ; Patient Compliance / psychology ; Analgesics / therapeutic use ; Physician-Patient Relations
    Language English
    Size x, 193 Seiten, Illustrationen
    Publisher Oxford University Press
    Publishing place New York
    Publishing country United States
    Document type Book
    HBZ-ID HT019471153
    ISBN 978-0-19-060007-5 ; 0-19-060007-1
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2017 A 1747 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: Balancing the Risks and Benefits of Opioid Therapy for Patients with Chronic Nonmalignant Pain: Have We Gone Too Far or Not Far Enough?

    Cheatle, Martin D

    Pain medicine (Malden, Mass.)

    2018  Volume 19, Issue 4, Page(s) 642–645

    MeSH term(s) Analgesics, Opioid ; Chronic Pain ; Humans ; Opioid-Related Disorders ; Prescriptions ; Risk Assessment
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2018-03-22
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2015903-1
    ISSN 1526-4637 ; 1526-2375
    ISSN (online) 1526-4637
    ISSN 1526-2375
    DOI 10.1093/pm/pny037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Impact of Prescription Drug Monitoring Programs and Prescribing Guidelines on Opioid Prescribing Behaviors: A Time for Institutional and Regulatory Changes.

    Cheatle, Martin D

    Pain medicine (Malden, Mass.)

    2017  Volume 18, Issue 5, Page(s) 823–824

    MeSH term(s) Analgesics, Opioid/therapeutic use ; Humans ; Practice Guidelines as Topic ; Practice Patterns, Physicians' ; Prescription Drug Monitoring Programs
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2017-04-18
    Publishing country England
    Document type Editorial
    ZDB-ID 2015903-1
    ISSN 1526-4637 ; 1526-2375
    ISSN (online) 1526-4637
    ISSN 1526-2375
    DOI 10.1093/pm/pnx083
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  4. Article ; Online: Suicidal thoughts and behaviors in patients with chronic pain, with and without co-occurring opioid use disorder.

    Cheatle, Martin D / Giordano, Nicholas A / Themelis, Kristy / Tang, Nicole K Y

    Pain medicine (Malden, Mass.)

    2023  Volume 24, Issue 8, Page(s) 941–948

    Abstract: Background: Individuals with chronic pain and a co-occurring substance use disorder present higher risk of suicide, but the individual and joint impacts of chronic pain and substance use disorders on suicide risk are not well defined. The objective of ... ...

    Abstract Background: Individuals with chronic pain and a co-occurring substance use disorder present higher risk of suicide, but the individual and joint impacts of chronic pain and substance use disorders on suicide risk are not well defined. The objective of this study was to exam the factors associated with suicidal thoughts and behaviors in a cohort of patients with chronic non-cancer pain (CNCP), with or without concomitant opioid use disorder (OUD).
    Design: Cross sectional cohort design.
    Setting: Primary care clinics, pain clinics, and substance abuse treatment facilities in Pennsylvania, Washington, and Utah.
    Subjects: In total, 609 adults with CNCP treated with long-term opioid therapy (>/= 6 months) who either developed an OUD (cases, n = 175) or displayed no evidence of OUD (controls, n = 434).
    Methods: The predicted outcome was elevated suicidal behavior in patients with CNCP as indicated by a Suicide Behavior Questionnaire-Revised (SBQ-R) score of 8 or above. The presence of CNCP and OUD were key predictors. Covariates included demographics, pain severity, psychiatric history, pain coping, social support, depression, pain catastrophizing and mental defeat.
    Results: Participants with CNCP and co-occurring OUD had an increased odds ratio of 3.44 in reporting elevated suicide scores as compared to participants with chronic pain only. Multivariable modeling revealed that mental defeat, pain catastrophizing, depression, and having chronic pain, and co-occurring OUD significantly increased the odds of elevated suicide scores.
    Conclusions: Patients with CNCP and co-morbid OUD are associated with a 3-fold increase in risk of suicide.
    MeSH term(s) Adult ; Humans ; Analgesics, Opioid/adverse effects ; Suicidal Ideation ; Chronic Pain/drug therapy ; Chronic Pain/epidemiology ; Chronic Pain/psychology ; Cross-Sectional Studies ; Opioid-Related Disorders/epidemiology ; Opioid-Related Disorders/drug therapy
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2023-04-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2015903-1
    ISSN 1526-4637 ; 1526-2375
    ISSN (online) 1526-4637
    ISSN 1526-2375
    DOI 10.1093/pm/pnad043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Facing the challenge of pain management and opioid misuse, abuse and opioid-related fatalities.

    Cheatle, Martin D

    Expert review of clinical pharmacology

    2016  Volume 9, Issue 6, Page(s) 751–754

    MeSH term(s) Analgesics, Opioid/administration & dosage ; Analgesics, Opioid/adverse effects ; Chronic Pain/drug therapy ; Drug Overdose/epidemiology ; Humans ; Opioid-Related Disorders/epidemiology ; Prescription Drug Misuse/statistics & numerical data
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2016-06
    Publishing country England
    Document type Journal Article
    ISSN 1751-2441
    ISSN (online) 1751-2441
    DOI 10.1586/17512433.2016.1160776
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Biopsychosocial Approach to Assessing and Managing Patients with Chronic Pain.

    Cheatle, Martin D

    The Medical clinics of North America

    2016  Volume 100, Issue 1, Page(s) 43–53

    Abstract: Chronic pain affects nearly one-third of the American population. Chronic pain can lead to a variety of problems for a pain sufferer, including developing secondary medical problems, depression, functional and vocational disability, opioid abuse and ... ...

    Abstract Chronic pain affects nearly one-third of the American population. Chronic pain can lead to a variety of problems for a pain sufferer, including developing secondary medical problems, depression, functional and vocational disability, opioid abuse and suicide. Current pain care models are deficient in providing a necessary comprehensive approach. Most patients with chronic pain are managed by primary care clinicians who are typically ill prepared to effectively and efficiently manage these cases. A biopsychosocial approach to evaluate and treat chronic pain is clinically and economically efficacious, but unique delivery systems are required to meet the challenge of access to specialty care.
    MeSH term(s) Adaptation, Psychological ; Analgesics, Opioid/therapeutic use ; Chronic Pain/psychology ; Chronic Pain/therapy ; Humans ; Medication Adherence/psychology ; Pain Management/methods ; Practice Guidelines as Topic ; Precision Medicine/methods ; Psychotherapy/methods ; Spirituality ; United States
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 215710-x
    ISSN 1557-9859 ; 0025-7125
    ISSN (online) 1557-9859
    ISSN 0025-7125
    DOI 10.1016/j.mcna.2015.08.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Trajectories and predictors of high-occurrence pain flares in ambulatory cancer patients on opioids.

    Meghani, Salimah H / Quinn, Ryan / Robinson, Andrew / Chittams, Jesse / Vapiwala, Neha / Naylor, Mary / Cheatle, Martin / Knafl, George J

    JNCI cancer spectrum

    2024  Volume 8, Issue 1

    Abstract: Background: Pain flares have a substantive impact on the quality of life and well-being of patients with cancer. We identified longitudinal trajectories (clusters) of cancer pain flares in ambulatory patients and sociodemographic and clinical predictors ...

    Abstract Background: Pain flares have a substantive impact on the quality of life and well-being of patients with cancer. We identified longitudinal trajectories (clusters) of cancer pain flares in ambulatory patients and sociodemographic and clinical predictors of these trajectories.
    Methods: In a prospective cohort study using ecological momentary assessment (mEMA), we collected patient-reported daily pain flare ratings data over 5 months and identified predictors and correlates using validated measures.
    Results: The mean age of the sample (N = 270) was 60.9 years (SD = 11.2), 64.8% were female, and 32.6% self-identified as African American. Four pain flare clusters were identified. The "high-occurrence" cluster (23% of patients) experienced 5.5 (SD = 5.47) daily flares, whereas low-moderate clusters (77%) reported 2.4 (SD = 2.74) daily flares (P < .000). Those in the high-occurrence cluster reported higher pain scores (P = .000), increased pain-related interference (P = .000), depressive symptoms (P = .023), lower quality of life (P = .001), and reduced pain self-efficacy (P = .006). Notably, 67.2% of those prescribed opioids as needed (PRN only) were in the high-occurrence pain flare cluster, compared with 27.9% with PRN and around-the-clock opioid prescriptions (P = .024). Individual predictors of high-occurrence pain flares were income below $30 000, unemployment, being African American, lower education level, Medicaid insurance, current opioid misuse (COMM), baseline inpatient hospital stay duration, and PRN-only opioid regimen. In the multiple predictor model, lower education level, unemployment, COMM score, extended inpatient duration, and PRN-only opioid regimen remained significant.
    Conclusion: In ambulatory patients with cancer, high occurrence of pain flares may be mitigated by attention to opioid prescription factors and addressing social determinants of health needs of underserved patients.
    MeSH term(s) United States ; Humans ; Female ; Middle Aged ; Male ; Analgesics, Opioid/therapeutic use ; Prospective Studies ; Quality of Life ; Symptom Flare Up ; Pain/drug therapy ; Neoplasms/complications ; Neoplasms/epidemiology
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ISSN 2515-5091
    ISSN (online) 2515-5091
    DOI 10.1093/jncics/pkae003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Prescription Opioid Misuse, Abuse, Morbidity, and Mortality: Balancing Effective Pain Management and Safety.

    Cheatle, Martin D

    Pain medicine (Malden, Mass.)

    2015  Volume 16 Suppl 1, Page(s) S3–8

    Abstract: Objective: The burgeoning rate of prescription opioid misuse, abuse, addiction, and opioid related overdose deaths has gained substantial professional and national media attention. This manuscript provides a narrative review and critique of the ... ...

    Abstract Objective: The burgeoning rate of prescription opioid misuse, abuse, addiction, and opioid related overdose deaths has gained substantial professional and national media attention. This manuscript provides a narrative review and critique of the literature on prescription opioid misuse, abuse, addiction and opioid-related mortality and discusses future research needs in this area.
    Design: Current literature on misuse, abuse, addiction and opioid related fatalities was reviewed in patients with chronic noncancer pain receiving long-term prescription opioid therapy.
    Results: There have been inconclusive results on the efficacy of long-term opioid therapy in patients with chronic pain but moderate level evidence of dose-dependent risk of harm. The estimated prevalence of prescription opioid abuse and opioid use disorders ranges from <1% to 40% due to the paucity of uniform definitions of what constitutes misuse, abuse, and addiction but several recent studies have developed unique methodology to more accurately assess these states in the pain population. The rate of opioid-related overdose deaths is not inconsequential and a number of patient related and medication specific risk factors have been identified that may provide a basis for risk mitigation strategies.
    Conclusions: Accurately assessing the prevalence of misuse, abuse, and addiction in the pain population has been challenging due to inconsistent definitions between studies. Additional high-quality research is needed in this area utilizing consistent definitions and in reducing the risk of opioid-related overdose fatalities.
    MeSH term(s) Analgesics, Opioid/adverse effects ; Analgesics, Opioid/therapeutic use ; Chronic Pain/drug therapy ; Drug Overdose/epidemiology ; Drug Overdose/prevention & control ; Humans ; Pain Management/adverse effects ; Prescription Drug Misuse/mortality ; Prescription Drug Misuse/prevention & control ; Prescriptions
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2015-10
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2015903-1
    ISSN 1526-4637 ; 1526-2375
    ISSN (online) 1526-4637
    ISSN 1526-2375
    DOI 10.1111/pme.12904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Suicidal ideation in patients with chronic pain: The risk-benefit of pharmacotherapy.

    Cheatle, Martin D

    Pain

    2014  Volume 155, Issue 12, Page(s) 2446–2447

    MeSH term(s) Antidepressive Agents/adverse effects ; Chronic Pain/complications ; Depression ; Humans ; Suicidal Ideation ; Suicide, Attempted/psychology
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2014-09-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 193153-2
    ISSN 1872-6623 ; 0304-3959
    ISSN (online) 1872-6623
    ISSN 0304-3959
    DOI 10.1016/j.pain.2014.09.032
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  10. Article ; Online: Assessing suicide risk in patients with chronic pain and depression.

    Cheatle, Martin D

    The Journal of family practice

    2014  Volume 63, Issue 6 Suppl, Page(s) S6–S11

    Abstract: Nearly one-half of all patients seen in primary care experience persistent pain, and major depressive disorder is a common comorbidity with chronic pain. ...

    Abstract Nearly one-half of all patients seen in primary care experience persistent pain, and major depressive disorder is a common comorbidity with chronic pain.
    MeSH term(s) Causality ; Chronic Pain/epidemiology ; Chronic Pain/psychology ; Comorbidity ; Depression/diagnosis ; Depression/epidemiology ; Depression/psychology ; Humans ; Male ; Middle Aged ; Risk Assessment ; Suicide/psychology ; Suicide/statistics & numerical data ; United States
    Language English
    Publishing date 2014-07-02
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 197883-4
    ISSN 1533-7294 ; 0094-3509
    ISSN (online) 1533-7294
    ISSN 0094-3509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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