LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 17

Search options

  1. Article: Adaptive optics, microscopy, and beyond: an interview with Professor Na Ji.

    Chen, Anderson

    Neurophotonics

    2024  Volume 11, Issue 2, Page(s) 20401

    Abstract: Prof. Na Ji (UC Berkeley) discusses her pioneering work and motivation in adaptive optics, microscopy, and beyond, in an interview with former trainee Anderson Chen (Prisma Therapeutics, Inc.). ...

    Abstract Prof. Na Ji (UC Berkeley) discusses her pioneering work and motivation in adaptive optics, microscopy, and beyond, in an interview with former trainee Anderson Chen (Prisma Therapeutics, Inc.).
    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type News
    ZDB-ID 2781943-7
    ISSN 2329-4248 ; 2329-423X
    ISSN (online) 2329-4248
    ISSN 2329-423X
    DOI 10.1117/1.NPh.11.2.020401
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Understanding Technology-Related Hidden Costs Associated With Virtual Care for Older Adults.

    Chen, Anderson / Chang, Tiffany / Chen, Lauren / Vahia, Ipsit V

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2023  Volume 31, Issue 8, Page(s) 653–654

    MeSH term(s) Humans ; Aged ; Virtual Reality ; Technology
    Language English
    Publishing date 2023-04-08
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2023.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Optical coherence tomography-based design for a real-time motion corrected scanning microscope.

    Tucker, Stephen S / Giblin, John T / Kiliç, Kivilcim / Chen, Anderson / Tang, Jianbo / Boas, David A

    Optics letters

    2023  Volume 48, Issue 14, Page(s) 3805–3808

    Abstract: While two-photon fluorescence microscopy is a powerful platform for the study of functional dynamics in living cells and tissues, the bulk motion inherent to these applications causes distortions. We have designed a motion tracking module based on ... ...

    Abstract While two-photon fluorescence microscopy is a powerful platform for the study of functional dynamics in living cells and tissues, the bulk motion inherent to these applications causes distortions. We have designed a motion tracking module based on spectral domain optical coherence tomography which compliments a laser scanning two-photon microscope with real-time corrective feedback. The module can be added to fluorescent imaging microscopes using a single dichroic and without additional contrast agents. We demonstrate that the system can track lateral displacements as large as 10
    MeSH term(s) Tomography, Optical Coherence ; Motion ; Microscopy, Confocal ; Artifacts ; Microscopy, Fluorescence
    Language English
    Publishing date 2023-07-14
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.490087
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: What We Know About Massively Multiplayer Online Role-Playing Games.

    Chen, Anderson / Mari, Sundus / Grech, Sabina / Levitt, James

    Harvard review of psychiatry

    2020  Volume 28, Issue 2, Page(s) 107–112

    Abstract: The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders defines internet gaming disorder without differentiating games from their respective genres, such as first-person shooter versus real-time strategy versus online gaming. Our ... ...

    Abstract The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders defines internet gaming disorder without differentiating games from their respective genres, such as first-person shooter versus real-time strategy versus online gaming. Our review of the literature on massively multiplayer online role-playing games (MMORPGs) suggests that MMORPGs are different from other games because they are the most addictive, and therefore deserve to be looked at separately. MMORPGs are internet platforms for online users to interact with each other in a virtual story line. The overview of the existing literature delineates the positive and negative aspects of MMORPGs and also the available evidence on neuroscientific and neuroanatomical correlates between internet gaming disorder and other addictions. Evidence shows that a player's characteristics and motivations can determine his or her risk of developing problematic play. Problematic MMORPG use may lead to mental disorders such as depression and addiction, and can negatively affect quality of life, and vice versa. Conversely, some players may benefit from being part of a social community and from using it as a learning platform or as a safe space to explore gender-identity issues. Brain circuitry and metabolism are changed through problematic MMORPG use, with the affected areas including the ventral striatum and left angular gyrus.
    MeSH term(s) Brain/physiopathology ; Humans ; Internet Addiction Disorder/physiopathology ; Internet Addiction Disorder/psychology ; Internet Addiction Disorder/therapy ; Mental Disorders/psychology ; Quality of Life
    Language English
    Publishing date 2020-03-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1174775-4
    ISSN 1465-7309 ; 1067-3229
    ISSN (online) 1465-7309
    ISSN 1067-3229
    DOI 10.1097/HRP.0000000000000247
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Opioid use and schizophrenia.

    Li, Kevin J / Chen, Anderson / DeLisi, Lynn E

    Current opinion in psychiatry

    2020  Volume 33, Issue 3, Page(s) 219–224

    Abstract: Purpose of review: To summarize the current literature regarding comorbid schizophrenia and opioid use disorder (OUD).: Recent findings: Epidemiological evidence is unclear on whether patients with schizophrenia have a higher rate of OUD. Patients ... ...

    Abstract Purpose of review: To summarize the current literature regarding comorbid schizophrenia and opioid use disorder (OUD).
    Recent findings: Epidemiological evidence is unclear on whether patients with schizophrenia have a higher rate of OUD. Patients with OUD have been shown to have a higher risk of developing schizophrenia. However, it is clear that patients with both schizophrenia and OUD are less likely to receive standard of care including medication-assisted treatment (MAT) for opiate use disorder and have worse outcomes compared with patients with schizophrenia who do not abuse opioids. OUD significantly increases the risk of converting patients from prodromal schizophrenia states to schizophrenia or schizoaffective disorder. Shared pathophysiology involving the kappa opioid receptor may help explain the relationships between schizophrenia and OUD. Second-generation antipsychotics, long-acting injectables, and MAT for OUD should be utilized in a dual-diagnosis and treatment approach for patients with schizophrenia and OUD.
    Summary: Exploration into the relationship between schizophrenia and opiate abuse is still in its infancy and requires a significant amount of future attention to clarify the epidemiology of this comorbidity, neurobiological relationship, shared genetic underpinnings, and possible treatments for both the psychotic symptoms and substance abuse.
    MeSH term(s) Antipsychotic Agents/therapeutic use ; Comorbidity ; Diagnosis, Dual (Psychiatry) ; Humans ; Opioid-Related Disorders/epidemiology ; Psychotic Disorders/drug therapy ; Psychotic Disorders/epidemiology ; Schizophrenia/drug therapy ; Schizophrenia/epidemiology
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2020-02-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ZDB-ID 645162-7
    ISSN 1473-6578 ; 0951-7367
    ISSN (online) 1473-6578
    ISSN 0951-7367
    DOI 10.1097/YCO.0000000000000593
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Screening, Assessment, and Pharmacologic Treatment of Mild Cognitive Impairment and Early Alzheimer's Disease: The Role for Monoclonal Antibodies.

    Weinberg, Marc S / Principe, Jessica L / Chen, Anderson / Chung, Sun Young / Arnold, Steven E / Stern, Theodore A

    The primary care companion for CNS disorders

    2023  Volume 25, Issue 6

    MeSH term(s) Humans ; Alzheimer Disease/complications ; Alzheimer Disease/diagnosis ; Alzheimer Disease/drug therapy ; Antibodies, Monoclonal ; Cognitive Dysfunction/complications ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/drug therapy ; Mental Disorders/therapy ; Psychiatry ; Hospitals, General ; Referral and Consultation
    Chemical Substances Antibodies, Monoclonal
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.23f03544
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Hypertensive Urgency and Emergency in Alcohol Withdrawal: A Literature Review.

    Bojdani, Ermal / Chen, Anderson / Zhang, Tina / Naqvi, Nida / Tahera, Dil

    The primary care companion for CNS disorders

    2019  Volume 21, Issue 6

    Abstract: Objective: To help clinicians recognize that hypertension, hypertensive urgency, and hypertensive emergency can arise in patients detoxifying from alcohol. Diagnostic and treatment implications are reviewed to help clinicians manage blood pressure in ... ...

    Abstract Objective: To help clinicians recognize that hypertension, hypertensive urgency, and hypertensive emergency can arise in patients detoxifying from alcohol. Diagnostic and treatment implications are reviewed to help clinicians manage blood pressure in these situations.
    Data sources: PubMed was searched with no restrictions on publication date or study type in June 2019 using the terms (alcohol withdrawal) AND hypertension.
    Study selection: Of 531 studies retrieved, all were reviewed, and articles older than 20 years were excluded. Of the remaining 158 articles, all were reviewed by full-text reading, and 17 were selected based on relevance. Seven UpToDate articles and 2 older papers were also included for relevance.
    Data extraction: Various other searches were also performed; however, no relevant hits resulted when the following terms were entered: (hypertensive urgency/emergency) AND alcohol withdrawal OR detoxification; (hypertensive urgency/emergency) AND (alcohol withdrawal OR detoxification) AND treatment-resistant hypertension.
    Results: Hypertension is typically self-limited in alcohol withdrawal syndrome; however, treatment is important to prevent hypertensive urgency or emergency. There is a paucity of data on how best to manage hypertension in patients withdrawing from alcohol, with treatment often individualized. Patients with underlying treatment-resistant hypertension may have more difficult-to-control blood pressure, especially in the first 24 hours of withdrawal.
    Conclusions: Multiple medications may be used to treat hypertension in the setting of alcohol withdrawal, with selection based on side effect profile and the patient's other comorbidities. In patients for whom there is concern for hypertensive urgency versus emergency, full medical evaluation is indicated to identify any potential end-organ damage.
    MeSH term(s) Alcohol-Related Disorders/complications ; Alcohol-Related Disorders/prevention & control ; Humans ; Hypertension/diagnosis ; Hypertension/etiology ; Hypertension/physiopathology ; Hypertension/therapy ; Risk Factors ; Substance Withdrawal Syndrome/complications ; Substance Withdrawal Syndrome/prevention & control ; Treatment Outcome
    Language English
    Publishing date 2019-12-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.19r02513
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Antipsychotics and the microbiota.

    Chen, Anderson / Park, Tae Yang / Li, Kevin J / DeLisi, Lynn E

    Current opinion in psychiatry

    2020  Volume 33, Issue 3, Page(s) 225–230

    Abstract: Purpose of review: The gut microbiota has been speculated to underpin metabolic changes associated with chronic antipsychotic use. The change in the gut microbiota can also cause abnormal absorbtion from the gut into the blood stream (leaky gut syndrome) ...

    Abstract Purpose of review: The gut microbiota has been speculated to underpin metabolic changes associated with chronic antipsychotic use. The change in the gut microbiota can also cause abnormal absorbtion from the gut into the blood stream (leaky gut syndrome) that can lead to inflammatory reactions, and thus, secondary damage to the brain and central nervous system. Our article aims to highlight relevant research on antipsychotic's effect on the microbiota and to point out future directions.
    Recent findings: Antipsychtoic use can result in specific microbiota changes, and it is important to differentiate this from the innate microbiota of the patient. It is important to treat these microbiota changes, as they are correlated with obesity, which is a negative contributor to the cardiovascular health of those suffering with schizophrenia. Ways to prevent antipsychotic-induced side-effects include antibiotic treatment, histamine 3 receptor blockade and metformin use.
    Summary: Given the dearth of current literature, more research is needed, however, to determine, which comes first in people with schizophrenia--an abnormal gut microbiota that elevates one's risk for schizophrenia or psychopharmacologic treatment of schizophrenia leading to secondary microbiota abnormalities or the negative symptoms of schizophrenia leading to obesity and its associated microbiota changes.
    MeSH term(s) Antipsychotic Agents/pharmacology ; Antipsychotic Agents/therapeutic use ; Gastrointestinal Microbiome/drug effects ; Humans ; Inflammation/microbiology ; Psychotic Disorders/drug therapy
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2020-02-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645162-7
    ISSN 1473-6578 ; 0951-7367
    ISSN (online) 1473-6578
    ISSN 0951-7367
    DOI 10.1097/YCO.0000000000000594
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: The Psychopharmacology Algorithm Project at the Harvard South Shore Program: An update on management of behavioral and psychological symptoms in dementia.

    Chen, Anderson / Copeli, Frank / Metzger, Eran / Cloutier, Alesia / Osser, David N

    Psychiatry research

    2020  Volume 295, Page(s) 113641

    Abstract: Geriatric patients with dementia frequently present with agitation, aggression, psychosis, and other behavioral and psychological symptoms of dementia (BPSD). We present an update of our previously published algorithms for the use of psychopharmacologic ... ...

    Abstract Geriatric patients with dementia frequently present with agitation, aggression, psychosis, and other behavioral and psychological symptoms of dementia (BPSD). We present an update of our previously published algorithms for the use of psychopharmacologic agents in these patients taking into account more recent studies and findings in meta-analyses, reviews, and other published algorithms. We propose three algorithms: BPSD in an emergent, urgent, and non-urgent setting. In the emergent setting when intramuscular (IM) administration is necessary, the first-line recommendation is for olanzapine (since IM aripiprazole, previously favored, is no longer available) and haloperidol injection is the second choice, followed by possible consideration of an IM benzodiazepine. In the urgent setting, the first line would be oral second-generation antipsychotics (SGAs) aripiprazole and risperidone. Perhaps next could be then prazosin, and lastly electroconvulsive therapy is a consideration. There are risks associated with these agents, and adverse effects can be severe. Dosing strategies, discontinuation considerations, and side effects are discussed. In the non-emergent setting, medications are proposed for use in the following order: trazodone, donepezil and memantine, antidepressants such as escitalopram and sertraline, SGAs, prazosin, and carbamazepine. Other options with less support but potential future promise are discussed.
    MeSH term(s) Academic Medical Centers/methods ; Aged ; Algorithms ; Antidepressive Agents/therapeutic use ; Antipsychotic Agents/therapeutic use ; Aripiprazole/therapeutic use ; Benzodiazepines/therapeutic use ; Citalopram/therapeutic use ; Dementia/diagnosis ; Dementia/psychology ; Dementia/therapy ; Electroconvulsive Therapy/methods ; Haloperidol/therapeutic use ; Humans ; Olanzapine/therapeutic use ; Psychopharmacology/methods ; Risperidone/therapeutic use
    Chemical Substances Antidepressive Agents ; Antipsychotic Agents ; Citalopram (0DHU5B8D6V) ; Benzodiazepines (12794-10-4) ; Aripiprazole (82VFR53I78) ; Haloperidol (J6292F8L3D) ; Risperidone (L6UH7ZF8HC) ; Olanzapine (N7U69T4SZR)
    Language English
    Publishing date 2020-12-13
    Publishing country Ireland
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 445361-x
    ISSN 1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
    ISSN (online) 1872-7123 ; 1872-7506
    ISSN 0925-4927 ; 0165-1781
    DOI 10.1016/j.psychres.2020.113641
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Treatment of Electroconvulsive Therapy-Emergent Hypomania and Mania: A Systematic Review of the Literature.

    Cloutier, Alesia A / Seiner, Stephen J / Solomon, Haley V / Jin, Shawn S / Chen, Anderson / Stolyar, Arkadiy / Forester, Brent P

    The Journal of clinical psychiatry

    2021  Volume 83, Issue 1

    Abstract: Objective:: Data Sources:: Study Selection:: Data Extraction:: Results:: Conclusions: ...

    Abstract Objective:
    Data Sources:
    Study Selection:
    Data Extraction:
    Results:
    Conclusions:
    MeSH term(s) Adolescent ; Adult ; Aged ; Bipolar Disorder/therapy ; Depressive Disorder/therapy ; Electroconvulsive Therapy/adverse effects ; Female ; Humans ; Male ; Mania/etiology ; Mania/therapy ; Middle Aged ; Young Adult
    Language English
    Publishing date 2021-11-16
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.21r13911
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top