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  1. Book ; Online ; E-Book: Introduction to scanning tunneling microscopy

    Chen, C. Julian

    (Monographs on the physics and chemistry of materials)

    2021  

    Abstract: The scanning tunnelling microscope (STM) was invented by Binnig and Rohrer and received a Nobel Prize of Physics in 1986. Together with the atomic force microscope (AFM), it provides non-destructive atomic and subatomic resolution on surfaces. Especially, ...

    Author's details C. Julian Chen
    Series title Monographs on the physics and chemistry of materials
    Abstract The scanning tunnelling microscope (STM) was invented by Binnig and Rohrer and received a Nobel Prize of Physics in 1986. Together with the atomic force microscope (AFM), it provides non-destructive atomic and subatomic resolution on surfaces. Especially, in recent years, internal details of atomic and molecular wavefunctions are observed and mapped with negligible disturbance. This is a reference book on the topic.
    Keywords Scanning tunneling microscopy
    Subject code 502.825
    Language English
    Size 1 online resource (275 pages) :, illustrations (black and white).
    Edition Third edition.
    Publisher Oxford University Press
    Publishing place Oxford, England
    Document type Book ; Online ; E-Book
    Note This edition also issued in print: 2021.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-5231-4120-4 ; 0-19-188990-3 ; 0-19-259856-2 ; 0-19-885655-5 ; 978-1-5231-4120-3 ; 978-0-19-188990-5 ; 978-0-19-259856-1 ; 978-0-19-885655-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Visible Light Communication (VLC)

    Chen, Chen

    2022  

    Keywords Technology: general issues ; History of engineering & technology ; visible light communication (VLC) ; dimming control ; constant transmission efficiency ; error performance ; light-emitting diode (LED) ; visible light communications ; deep learning ; bit error rate ; orthogonal frequency division multiplexing ; index modulation ; POF ; FSO ; LiFi ; LED ; orthogonal frequency division multiplexing (OFDM) ; power efficiency ; peak-to-average-power ratio (PAPR) ; pre-distorted enhanced ; underwater optical wireless communication (UOWC) ; ADO-OFDM ; gamma-gamma function ; full-duplex ; long-reach ; photon counting ; vehicular visible light communication (VVLC) ; intelligent reflecting surface (IRS) ; the number of mirrors ; energy efficiency (EE) ; carrierless amplitude and phase (CAP) modulation ; pairwise coding (PWC) ; dual-mode index modulation (DM) ; chaotic encryption ; visible light positioning (VLP) ; free-space communication ; RGB LED ; non-orthogonal multiple access (NOMA) ; superposition constellation adjustment ; successive interference cancellation ; bit error ratio ; NOMA triangle ; underwater wireless optical communication ; temporal dispersion ; bandwidth limitation ; Monte Carlo method ; maximum likelihood sequence estimation ; visible light communication ; nonlinear equalization ; reservoir computing ; neural network (NN) ; autoencoder (AE) ; transceiver design ; nonlinearity ; VLC ; predistortion ; coefficient approximation ; BLSTM ; orthogonal frequency-division multiplexing ; sampling frequency offset ; visible light communications (VLC) ; mmWave communications ; channel modeling ; channel propagation characteristics ; path loss ; delay spread (DS) ; Ricean K-factor ; cluster characteristics ; n/a
    Language 0|e
    Size 1 electronic resource (240 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021610584
    ISBN 9783036540887 ; 3036540881
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: Mapping the terrain: a scoping review of empirical studies on the big five personality traits and QoL in China.

    Chen, Cuiren

    Frontiers in psychology

    2024  Volume 14, Page(s) 1335657

    Abstract: The relationship between personality traits and Quality of Life (QoL) has garnered increasing scholarly attention, particularly within the context of China. This scoping review synthesizes existing literature on the connection between the Big Five ... ...

    Abstract The relationship between personality traits and Quality of Life (QoL) has garnered increasing scholarly attention, particularly within the context of China. This scoping review synthesizes existing literature on the connection between the Big Five personality traits (Openness, Conscientiousness, Extraversion, Agreeableness, and Neuroticism) and QoL among the Chinese population. The review explores correlations, measurement instruments, and theoretical frameworks employed in these studies. The study's significance lies in the profound implications for healthcare policies, organizational behavior, and social welfare programs in China, where rapid social and economic changes impact well-being. Investigating personality traits' impact on QoL can inform tailored interventions benefiting diverse Chinese subpopulations. This review addresses three primary research questions: (1) How do the Big Five personality traits correlate with QoL in different Chinese subpopulations, and what are the mediating or moderating factors? (2) What instruments assess these traits and QoL in the Chinese cultural context, and how are they validated? (3) What theoretical or disciplinary frameworks guide this research in China? Following a systematic PRISMA-ScR framework and a customized "C-BFQLC" protocol, the study identified 170 relevant documents. After rigorous screening, ten studies met the inclusion criteria, constituting 5.03% of the initial records. This scoping review critically examines the interplay between the Big Five personality traits and QoL in China, a context marked by rapid socioeconomic changes and cultural diversity. Employing a systematic approach guided by the PRISMA-ScR framework and our unique 'C-BFQLC' protocol, we meticulously analyzed 170 documents, selecting nine that met our rigorous inclusion criteria. Despite the emerging nature of this research area in the Chinese context, our study reveals significant insights into how individual personality traits influence various dimensions of well-being. The implications of these findings are profound, extending beyond academic discourse to inform healthcare policies, organizational behavior, and social welfare programs in China. Our review not only offers a comprehensive synthesis of the current research landscape but also identifies critical gaps in the literature. It emphasizes the urgent need for further culturally nuanced research to understand the complex dynamics of personality traits and QoL in China. This work lays a foundational framework for future investigations and the development of tailored interventions aimed at enhancing the well-being of diverse Chinese populations, including the elderly, people with disabilities, and specific occupational groups.
    Language English
    Publishing date 2024-01-12
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1335657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Correlation of structure with function: The role of optical coherence tomography in neuro-ophthalmology.

    Chen, Celia

    Clinical & experimental ophthalmology

    2024  Volume 52, Issue 2, Page(s) 135–136

    MeSH term(s) Humans ; Ophthalmology/methods ; Tomography, Optical Coherence/methods ; Optic Nerve Diseases
    Language English
    Publishing date 2024-03-07
    Publishing country Australia
    Document type Editorial
    ZDB-ID 2014008-3
    ISSN 1442-9071 ; 1442-6404
    ISSN (online) 1442-9071
    ISSN 1442-6404
    DOI 10.1111/ceo.14360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Conference proceedings ; Online: Turbulence mixing processes in typhoon boundary layer under high wind speed condition during landfall

    Chen, C.

    XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

    2023  

    Abstract: This study investigated surface layer turbulence characteristics and parameters using 20 Hz eddy covariance data collected from five heights with winds up to 42.27 m s–1 when Super Typhoon Maria (2018) made landfall. The dependence of these parameters ... ...

    Abstract This study investigated surface layer turbulence characteristics and parameters using 20 Hz eddy covariance data collected from five heights with winds up to 42.27 m s–1 when Super Typhoon Maria (2018) made landfall. The dependence of these parameters including eddy diffusivities for momentum (Km) and heat (Kt), vertical mixing length (Lm), and strain rate (S) on wind speed (un), height, and radii was examined. The results show that momentum fluxes (τ), turbulent kinetic energy (TKE), and Km had a parabolic dependence on un at all five heights outside three times the RMW, the maximum of Km and S increased from the surface to a maximum value at a height of 50 m, and then decreased with greater heights. However, Km and S were nearly constant with wind and height within two to three times the RMW from the typical cyclone (TC) center before landfall. Our results also found the |τ|, TKE, and Km were larger than over oceanic areas at any given wind, and Km was about one to two orders of magnitude bigger than Kt. The turbulence characteristic and parameters’ change with height and radii from the TC center should be accounted for in sub-grid scale physical processes of momentum fluxes in numerical TC models.
    Subject code 551
    Language English
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: The relationship between parental depression and child internalizing and externalizing problems: The roles of parenting stress and child maltreatment.

    Chen, Chen

    Frontiers in public health

    2023  Volume 11, Page(s) 962951

    Abstract: Introduction: Although the relationships between parental mental health and child internalizing and externalizing problems have been explored by previous studies, the pathways between these two variables need further exploration. The present study aims ... ...

    Abstract Introduction: Although the relationships between parental mental health and child internalizing and externalizing problems have been explored by previous studies, the pathways between these two variables need further exploration. The present study aims to explore the relationships between parental depression and child internalizing and externalizing problems and to examine the roles of parenting stress and child maltreatment in those relationships within the Chinese cultural context.
    Method: Data were collected from 855 Chinese families with preschool-aged children, and mediation analysis was used to examine the pathways between these variables.
    Results: The results show that parental depression is positively associated with child internalizing and externalizing problems, and child maltreatment and the combination of parenting stress and child maltreatment mediated the relationships between parental depression and child internalizing and externalizing problems, respectively. These findings suggest that parental depression not only has a direct effect on child internalizing and externalizing problems but also has an indirect effect
    Discussion: Decreasing the levels of parenting stress and child maltreatment should be applied in interventions to break the relationships between parental depression and child internalizing and externalizing problems within the Chinese cultural context.
    MeSH term(s) Child, Preschool ; Humans ; Child ; Parenting/psychology ; Depression/psychology ; Child Abuse ; Child Behavior/psychology ; Parents/psychology
    Language English
    Publishing date 2023-02-07
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.962951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Inhibiting degradation of 2-arachidonoylglycerol as a therapeutic strategy for neurodegenerative diseases.

    Chen, Chu

    Pharmacology & therapeutics

    2023  Volume 244, Page(s) 108394

    Abstract: Endocannabinoids are endogenous lipid signaling mediators that participate in a variety of physiological and pathological processes. 2-Arachidonoylglycerol (2-AG) is the most abundant endocannabinoid and is a full agonist of G-protein-coupled cannabinoid ...

    Abstract Endocannabinoids are endogenous lipid signaling mediators that participate in a variety of physiological and pathological processes. 2-Arachidonoylglycerol (2-AG) is the most abundant endocannabinoid and is a full agonist of G-protein-coupled cannabinoid receptors (CB1R and CB2R), which are targets of Δ
    MeSH term(s) Animals ; Endocannabinoids/metabolism ; Neurodegenerative Diseases/drug therapy ; Neuroinflammatory Diseases ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use
    Chemical Substances glyceryl 2-arachidonate (8D239QDW64) ; Endocannabinoids ; Neuroprotective Agents
    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 194735-7
    ISSN 1879-016X ; 0163-7258
    ISSN (online) 1879-016X
    ISSN 0163-7258
    DOI 10.1016/j.pharmthera.2023.108394
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: 10th anniversary of discovering cGAMP: synthesis and beyond.

    Chen, Chuo

    Organic chemistry frontiers : an international journal of organic chemistry

    2023  Volume 10, Issue 4, Page(s) 1086–1098

    Abstract: The discovery of cGAMP in 2012 filled an important gap in our understanding of innate immune signaling. It has been known for over a century that DNA can induce immune responses, but the underlying mechanism was not clear. With the identification of ... ...

    Abstract The discovery of cGAMP in 2012 filled an important gap in our understanding of innate immune signaling. It has been known for over a century that DNA can induce immune responses, but the underlying mechanism was not clear. With the identification of STING as a key player in interferon induction, the DNA detector that activates STING was the last missing link in TBK1-IRF3 signaling. Somewhat unexpectedly, it turns out that nature relays the DNA danger signal through a small molecule. cGAMP is a cyclic dinucleotide produced from cyclodimerization of ATP and GTP upon detection of cytosolic DNA by cGAS, a previously uncharacterized protein, to promote the assembly of the STING signalosome. This article covers a personal account of the discovery of cGAMP, a short history of the relevant nucleotide chemistry, and a summary of the latest development in this field of research in chemistry. It is the author's hope that, with a historic perspective, the readers can better appreciate the synergy between chemistry and biology in drug development.
    Language English
    Publishing date 2023-01-25
    Publishing country England
    Document type Journal Article
    ISSN 2052-4110
    ISSN 2052-4110
    DOI 10.1039/d2qo02033e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: TDP-43 is a key molecule accelerating development of Alzheimer's disease following traumatic brain injury.

    Chen, Chu

    Neural regeneration research

    2023  Volume 19, Issue 5, Page(s) 955–956

    Language English
    Publishing date 2023-10-20
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.385301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: To go or not to go in phase 2/3 oncology trials, a critical question with a unified answer.

    Chen, Cong

    Contemporary clinical trials

    2023  Volume 128, Page(s) 107146

    Abstract: The decision on how fast to go from single-arm Phase 1 after efficacy single-detection to randomized-controlled Phase 2/3 in oncology drug development is multifaceted and complex, if not often contentious. To facilitate the process, we have incorporated ... ...

    Abstract The decision on how fast to go from single-arm Phase 1 after efficacy single-detection to randomized-controlled Phase 2/3 in oncology drug development is multifaceted and complex, if not often contentious. To facilitate the process, we have incorporated all viable options including the under-utilized adaptive Phase 2/3 designs into a comprehensive decision matrix for completeness and transparency. Illustrated with the 2-in-1 adaptive Phase 2/3 design, a formal decision analysis that explicitly optimizes the tradeoff between cost and benefit reveals a surprisingly robust efficacy bar for Go-No Go transition. It implies that similar robust bars exist for other adaptive Phase 2/3 designs, which remove a major hurdle for their wider adoption in practice.
    MeSH term(s) Humans ; Neoplasms/drug therapy ; Medical Oncology ; Research Design ; Drug Development
    Language English
    Publishing date 2023-03-13
    Publishing country United States
    Document type Clinical Trial, Phase III ; Clinical Trial, Phase II ; Journal Article
    ZDB-ID 2182176-8
    ISSN 1559-2030 ; 1551-7144
    ISSN (online) 1559-2030
    ISSN 1551-7144
    DOI 10.1016/j.cct.2023.107146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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