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  1. Article ; Online: Femtosecond laser-assisted cataract surgery for complex cataracts - A review.

    Chen, David Z / Chee, Soon-Phaik

    Indian journal of ophthalmology

    2024  Volume 72, Issue 5, Page(s) 629–636

    Abstract: Since its inception in 2009, femtosecond laser-assisted cataract surgery (FLACS) has become an alternative to conventional phacoemulsification cataract surgery (CPCS). Clinical studies were unable to demonstrate superior visual outcomes, but revealed ... ...

    Abstract Since its inception in 2009, femtosecond laser-assisted cataract surgery (FLACS) has become an alternative to conventional phacoemulsification cataract surgery (CPCS). Clinical studies were unable to demonstrate superior visual outcomes, but revealed reduced endothelial cell loss. More recently, the cost-effectiveness of FLACS over CPCS in routine cataract surgeries has been challenged. However, the unique abilities of FLACS to customize anterior capsulotomies precisely, soften and fragment the nucleus without capsular bag stress, and create corneal incisions may have special utility in complex cataract and less-common scenarios. In this article, we review the unique role of FLACS in complex cataract surgeries and how it could play a role to improve the safety and predictability of nonroutine cataract surgery.
    MeSH term(s) Humans ; Laser Therapy/methods ; Cataract Extraction/methods ; Cataract/complications ; Visual Acuity
    Language English
    Publishing date 2024-04-22
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/IJO.IJO_2996_23
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  2. Article: Comparison of complication rates between femtosecond laser-assisted cataract surgery and conventional phacoemulsification cataract surgery.

    Jin, Eric Y / Chen, David Z

    International journal of ophthalmology

    2023  Volume 16, Issue 1, Page(s) 156–158

    Language English
    Publishing date 2023-01-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2663246-9
    ISSN 2227-4898 ; 2222-3959
    ISSN (online) 2227-4898
    ISSN 2222-3959
    DOI 10.18240/ijo.2023.01.25
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  3. Article ; Online: Rupture of a posterior polar cataract after peribulbar block.

    Chen, David Z / Hernstadt, David J / Lin, Hazel A / Chee, Soon-Phaik

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

    2024  

    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Letter
    ZDB-ID 80091-0
    ISSN 1715-3360 ; 0008-4182
    ISSN (online) 1715-3360
    ISSN 0008-4182
    DOI 10.1016/j.jcjo.2024.03.008
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  4. Article: Clinical outcome of bacterial endogenous endophthalmitis in 15 patients.

    Goenadi, Catherina J / Chew, Kean Lee / Gopal, Lingam / Chen, David Z

    Annals of the Academy of Medicine, Singapore

    2023  Volume 52, Issue 1, Page(s) 44–47

    MeSH term(s) Humans ; Endophthalmitis/drug therapy ; Endophthalmitis/microbiology ; Eye Infections, Bacterial/drug therapy ; Eye Infections, Bacterial/microbiology ; Anti-Bacterial Agents/therapeutic use ; Retrospective Studies
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-02-01
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    DOI 10.47102/annals-acadmedsg.2022407
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  5. Article: Neuro-Behçet's disease presenting as isolated intracranial hypertension.

    Lin, Hazel A / Chen, David Z / Tan, Clement WT

    Annals of the Academy of Medicine, Singapore

    2021  Volume 50, Issue 1, Page(s) 88–89

    MeSH term(s) Behcet Syndrome/complications ; Behcet Syndrome/diagnosis ; Humans ; Intracranial Hypertension/diagnosis ; Intracranial Hypertension/etiology ; Magnetic Resonance Imaging
    Language English
    Publishing date 2021-02-24
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    DOI 10.47102/annals-acadmedsg.2020189
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  6. Article: Teleophthalmology and its evolving role in a COVID-19 pandemic: A scoping review.

    Chong, Jiamin Charmaine / Tan, Chai-Hoon Nowel / Chen, David Z

    Annals of the Academy of Medicine, Singapore

    2021  Volume 50, Issue 1, Page(s) 61–76

    Abstract: Introduction: Teleophthalmology may assist the healthcare sector in adapting to limitations imposed on clinical practice by a viral pandemic. A scoping review is performed in this study to assess the current applications of teleophthalmology for its ... ...

    Abstract Introduction: Teleophthalmology may assist the healthcare sector in adapting to limitations imposed on clinical practice by a viral pandemic. A scoping review is performed in this study to assess the current applications of teleophthalmology for its suitability to diagnose, monitor or manage ophthalmological conditions with accuracy.
    Methods: A search of PubMed was conducted for teleophthalmology-related articles published from 1 January 2018 to 4 May 2020. Only articles that focused on the use of teleophthalmology in terms of diagnosis and management, as well as its benefits and detriments, were included. The Mixed Methods Appraisal Tool (MMAT) was used to assess the quality of the included articles.
    Results: A total of 38 articles were assessed at the full-text level. There were 2 qualitative studies and 1 quantitative randomised controlled trial, while the majority were either quantitative descriptive studies (19, 50.0%) or quantitative non-randomised studies (16, 42.1%). Overall, 8 studies described reducing manpower requirements, 4 described reducing direct patient-doctor contact, 17 described storage of medical imaging and clinical data, and 9 described real-time teleconferencing. The MMAT analysis revealed limitations in appropriate sampling strategy in both quantitative non-randomised studies (9 of 16, 56.3%) and quantitative descriptive studies (9 of 19, 47.4%). Cost-effectiveness of teleophthalmology was not performed in any included study.
    Conclusion: This current review of the various aspects of teleophthalmology describes how it may potentially assist the healthcare sector to cope with the limitations imposed by a viral pandemic through technology. Further research is required to evaluate the cost-effectiveness of the various strategies.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/transmission ; Humans ; Ophthalmology/organization & administration ; Telemedicine/organization & administration
    Language English
    Publishing date 2021-02-17
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    DOI 10.47102/annals-acadmedsg.2020459
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  7. Article ; Online: Association between sleep and myopia in children and adolescents: a systematic review and meta-analysis.

    Jin, Eric / Lee, Chae Eun / Li, Hengtong / Tham, Yih-Chung / Chen, David Z

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

    2023  

    Abstract: Purpose: There is a scarcity of literature focusing on sleep's impact on myopia in children despite an epidemic rise of myopia among the age group and the importance of early prevention. As such, this systematic review-meta-analysis aims to evaluate the ...

    Abstract Purpose: There is a scarcity of literature focusing on sleep's impact on myopia in children despite an epidemic rise of myopia among the age group and the importance of early prevention. As such, this systematic review-meta-analysis aims to evaluate the association between various aspects of sleep and myopia in children and adolescents aged 0-19 years.
    Methods: We searched PubMed, EMBASE, and Cochrane Library on 08/12/2022 for studies reporting sleep in relation to myopia among children and adolescents. Myopia was defined as spherical equivalent refraction < -0.5 diopter. The primary outcome was the relationship between sleep duration and myopia prevalence. Secondary outcomes include the effect of sleep quality, bedtime, and waketime on myopia prevalence, incidence, and progression. Odds ratio (OR) was estimated with a 95% confidence interval (95% CI).
    Results: Eighteen studies (49,277 participants) were included in the review, and six studies (14,116 participants) were included in the meta-analysis for the primary outcome. There was no significant correlation between sleep and myopia prevalence (OR = 0.905, 95% CI = 0.782 to 1.047). Some studies suggested that better sleep quality (2 of 6 studies), earlier bedtime (3 of 5 studies), and later waketimes (2 of 3 studies) had protective effects on myopia.
    Conclusion: Sleep duration did not affect myopia prevalence in children, while other aspects of sleep had plausible but inconclusive impacts on myopia development and progression. More research with diverse populations and standardized methods of reporting is needed.
    Language English
    Publishing date 2023-12-13
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 8435-9
    ISSN 1435-702X ; 0721-832X
    ISSN (online) 1435-702X
    ISSN 0721-832X
    DOI 10.1007/s00417-023-06338-0
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  8. Article ; Online: A data-driven approach to evaluate factors affecting resident performance in cataract surgery.

    Tan, Darren Ngiap Hao / Tan, Marcus / Liew, Hariz / Shen, Liang / Ngiam, Kee Yuan / Chen, David Z

    International ophthalmology

    2023  Volume 43, Issue 9, Page(s) 3269–3277

    Abstract: Purpose: To evaluate the operative duration and clinical performance of ophthalmology residents performing standard phacoemulsification cataract surgeries using information available from electronic health records (EHR).: Methods: This is a ... ...

    Abstract Purpose: To evaluate the operative duration and clinical performance of ophthalmology residents performing standard phacoemulsification cataract surgeries using information available from electronic health records (EHR).
    Methods: This is a retrospective cohort study. De-identified surgical records of all standard phacoemulsifications performed in a tertiary institution between 1st January 2015 and 8th August 2018 were retrieved from the hospital EHR. The main outcome measures were improvement in operative duration with case experience, corrected distance visual acuity (CDVA) improvement, and intra-operative complication rates.
    Results: Twelve ophthalmology residents performed a total of 1427 standard phacoemulsifications. The median operative duration was 27 min (interquartile range, 22-34 min), which improved from 31 to 24 min (before the 101st case [Group 1] versus 101st case onwards [Group 2], p < 0.001). Gradient change analysis (non-linear regression) showed significant reduction until the 100th case (p = 0.043). Older patients (0.019), worse pre-operative CDVA (0.343), and surgery performed by Group 1 (1.115) were significantly associated with operative duration above 30 min. LogMAR CDVA improved from a mean of 0.57 ± 0.52 pre-operatively to 0.10 ± 0.18 post-operatively (p < 0.001). Posterior capsule rupture (PCR) rate decreased from 4.0% [Group 1] to 2.1% [Group 2] (p = 0.096), while overall complication rate decreased from 8.9% to 3.1% (p < 0.001).
    Conclusion: The median operative duration reduced consistently with surgical experience for the first 100 cases. Older patients, poorer pre-operative VA, and surgical experience of less than 100 cases were significantly associated with an operative duration above 30 min. There was a statistically significant decrease in complication rate between Group 1 and 2.
    MeSH term(s) Humans ; Ophthalmology ; Retrospective Studies ; Cataract Extraction ; Phacoemulsification ; Cataract
    Language English
    Publishing date 2023-05-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-023-02730-1
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  9. Article ; Online: Risk of keratinocyte carcinomas following extracorporeal photopheresis among lung transplant recipients: A retrospective cohort study.

    Chen, David Z / Wang, Cynthia X / Huecker, Julia B / Russell, Aaron J / Anadkat, Milan J

    Journal of the American Academy of Dermatology

    2023  Volume 90, Issue 2, Page(s) 388–390

    MeSH term(s) Humans ; Photopheresis ; Transplant Recipients ; Retrospective Studies ; Lung ; Lung Transplantation/adverse effects ; Carcinoma ; Keratinocytes ; Skin Neoplasms/etiology ; Graft Rejection
    Language English
    Publishing date 2023-10-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.09.067
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  10. Article: Microbial patterns of

    Chen, David Z / Chai, Charmaine / Tan, Anna / Ray, Manotosh

    Annals of the Academy of Medicine, Singapore

    2021  Volume 50, Issue 6, Page(s) 494–496

    MeSH term(s) Acanthamoeba Keratitis/diagnosis ; Acanthamoeba Keratitis/epidemiology ; Hospitals ; Humans ; Referral and Consultation ; Retrospective Studies ; Singapore/epidemiology
    Language English
    Publishing date 2021-07-09
    Publishing country Singapore
    Document type Journal Article ; Observational Study
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    DOI 10.47102/annals-acadmedsg.2020507
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