LIVIVO - Search results -

Search results

Result 1 - 10 of total 188

Search options

Article ; Online: Engineering Chlorophyll, Bacteriochlorophyll, and Carotenoid Biosynthetic Pathways in

Chen, Guangyu E / Hunter, C Neil

ACS synthetic biology

2023 Volume 12, Issue 8, Page(s) 2236–2244

Abstract: The biosynthesis of chlorophylls (Chls) and bacteriochlorophylls (BChls) represents a key aspect of photosynthesis research. Our previous work assembled the complete pathway for the synthesis of ... ...

Abstract	The biosynthesis of chlorophylls (Chls) and bacteriochlorophylls (BChls) represents a key aspect of photosynthesis research. Our previous work assembled the complete pathway for the synthesis of Chl
MeSH term(s)	Chlorophyll/metabolism ; Bacteriochlorophylls/genetics ; Bacteriochlorophylls/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Biosynthetic Pathways/genetics ; Carotenoids/metabolism
Chemical Substances	Chlorophyll (1406-65-1) ; Bacteriochlorophylls ; Carotenoids (36-88-4)
Language	English
Publishing date	2023-08-02
Publishing country	United States
Document type	Letter ; Research Support, Non-U.S. Gov't
ISSN	2161-5063
ISSN (online)	2161-5063
DOI	10.1021/acssynbio.3c00237
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Spare Parts Stocking Decision Strategy and Service Logistics Cost Optimization of Two-Echelon Service Logistics System considering Multifailure Mode.

Wang, Ruiqi / Chen, Guangyu

publication RETRACTED

Computational intelligence and neuroscience

2022 Volume 2022, Page(s) 7607985

Abstract: For the repair level and spare parts stocking decision problems, generally METRIC type methods and level of repair analysis (LORA) are used separately. In practical engineering, the repair level of large-scale systems is usually judged according to the ... ...

Abstract	For the repair level and spare parts stocking decision problems, generally METRIC type methods and level of repair analysis (LORA) are used separately. In practical engineering, the repair level of large-scale systems is usually judged according to the failure modes. The method of judging the repair level by the maintenance success rate is no longer applicable. In the case of multiple failure modes of a large-scale system, considering the requirements of system availability, we build a spare parts stocking decision and service logistics cost optimization model of a two-echelon service logistics system. Aiming at the spare parts stocking allocation problem caused by multiple failure modes, we improve the iterative greedy heuristic algorithm to find the global optimal stocking allocation strategies. Finally, through the analysis of typical examples, the correctness and effectiveness of the model and algorithm are verified. The impact of multifailure mode spare parts stocking allocation strategies on availability and service logistics cost is analyzed. The research results are helpful to simplify the support engineering design process of system engineers and have certain theoretical and application value.
MeSH term(s)	Algorithms
Language	English
Publishing date	2022-03-08
Publishing country	United States
Document type	Journal Article ; Retracted Publication
ZDB-ID	2388208-6
ISSN	1687-5273 ; 1687-5273
ISSN (online)	1687-5273
ISSN	1687-5273
DOI	10.1155/2022/7607985
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Recent progress of heterogeneous catalysts for transfer hydrogenation under the background of carbon neutrality.

Chen, Guangyu / Ma, Jun / Gong, Wanbing / Li, Jiayi / Li, Zheyue / Long, Ran / Xiong, Yujie

Nanoscale

2024 Volume 16, Issue 3, Page(s) 1038–1057

Abstract: Under the background of carbon neutrality, the direct conversion of greenhouse ... ...

Abstract	Under the background of carbon neutrality, the direct conversion of greenhouse CO
Language	English
Publishing date	2024-01-18
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d3nr05207a
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Expressions of CXCR3 and PD-1 on T cells and their clinical relevance in colorectal cancer.

Wang, Sen / Zhang, Yangyang / Chen, Guangyu / Zhao, Peng / Wang, Xiaoming / Xu, Benling / Yuan, Long

International immunopharmacology

2024 Volume 132, Page(s) 111988

Abstract: Purpose: Clinical application of immunotherapy represented by Programmed Death-1 (PD-1) monoclonal antibody has changed the treatment paradigm for colorectal cancer (CRC), and tumor-infiltrating T lymphocytes are critical for anti-PD-1 therapy in CRC. ... ...

Abstract	Purpose: Clinical application of immunotherapy represented by Programmed Death-1 (PD-1) monoclonal antibody has changed the treatment paradigm for colorectal cancer (CRC), and tumor-infiltrating T lymphocytes are critical for anti-PD-1 therapy in CRC. However, there are few studies on the relationship between the expression CXCR3 on T lymphocytes and the clinical aspects of CRC. In this study, we analyzed the expression levels of CXCR3 and PD-1 in CD8 Methods: We detected the expressions of CXCR3 and PD-1 on T lymphocytes in peripheral blood of healthy donors as well as peripheral blood, tumor tissue and para-cancerous tissues of patients with CRC using flow cytometry. We also analyzed the relationship between the expressions of CXCR3 and PD-1 on T lymphocytes and the pathological characteristics of CRC using t test. Results: Expression of CXCR3 on tumor-infiltrating T lymphocytes was lower, whereas the expression of PD-1 was higher than that on para-cancerous tissues and PB in patients with CRC. In patients with lymph node metastasis of CRC, the expressions levels of CXCR3 Conclusion: Expressions of CXCR3 and PD-1 on tumor-infiltrating T lymphocytes are related to the development of CRC and metastasis, providing clues for exploring the pathogenesis of CRC and developing new strategies for tumor immunotherapy.
MeSH term(s)	Humans ; Receptors, CXCR3/metabolism ; Colorectal Neoplasms/immunology ; Colorectal Neoplasms/pathology ; Programmed Cell Death 1 Receptor/metabolism ; Female ; Male ; Middle Aged ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; CD8-Positive T-Lymphocytes/immunology ; Aged ; CD4-Positive T-Lymphocytes/immunology ; Lymphatic Metastasis ; Adult ; Clinical Relevance
Chemical Substances	Receptors, CXCR3 ; Programmed Cell Death 1 Receptor ; CXCR3 protein, human ; PDCD1 protein, human
Language	English
Publishing date	2024-04-08
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2043785-7
ISSN	1878-1705 ; 1567-5769
ISSN (online)	1878-1705
ISSN	1567-5769
DOI	10.1016/j.intimp.2024.111988
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 5408: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Insignificant Difference in Early Post-injury Gene Expression Between Patients with Burns Only and Those with Inhalation Injury: A Bioinformatics Analysis.

Jiang, Huihao / Dou, Zhe / Chen, Guangyu / Zhang, Guoan / Du, Weili

Journal of burn care & research : official publication of the American Burn Association

2023 Volume 44, Issue 6, Page(s) 1509–1518

Abstract: Airway obstruction is fatal but common among burn patients in the early period after inhalation injury, during which most tracheotomies are performed within 48 h post-injury. Inflammation is common in laryngoscopy; however, the related gene expression ... ...

Abstract	Airway obstruction is fatal but common among burn patients in the early period after inhalation injury, during which most tracheotomies are performed within 48 h post-injury. Inflammation is common in laryngoscopy; however, the related gene expression has rarely been studied. In this study, we obtained the data of healthy control and patient samples collected within 8-48 hours post-injury from the Gene Expression Omnibus database and classified them into 10 inhalation-injury patients, 6 burn-only, and 10 healthy controls. Differential gene expression was identified between the patient groups; however, principal component analysis and cluster analysis indicated a similarity between groups. Furthermore, enrichment analysis, Kyoto Encyclopedia of Genes and Genomes, and gene set enrichment analyses showed no significant differences in immune regulation and cell adjustment between the patient groups; but differences were shown when comparing either patient group to the healthy control group, including prominent regulation in inflammatory cells, infection, and cell adjustment. Thus, the gene expression in inhalation injury and burn-only patients does not significantly differ in the early period after injury, especially in inflammation, indicating the absence of specific diagnostic markers or anti-inflammatory treatment in inhalation injury patients, with the potential to identify more subtle differences. Further research is warranted.
MeSH term(s)	Humans ; Burns ; Burns, Inhalation/surgery ; Laryngoscopy ; Inflammation ; Gene Expression
Language	English
Publishing date	2023-06-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2224246-6
ISSN	1559-0488 ; 1559-047X
ISSN (online)	1559-0488
ISSN	1559-047X
DOI	10.1093/jbcr/irad085
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6223: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Protochlorophyllide synthesis by recombinant cyclases from eukaryotic oxygenic phototrophs and the dependence on Ycf54.

Chen, Guangyu E / Hunter, C Neil

The Biochemical journal

2020 Volume 477, Issue 12, Page(s) 2313–2325

Abstract: The unique isocyclic E ring of chlorophylls contributes to their role as light-absorbing pigments in photosynthesis. The formation of the E ring is catalyzed by the Mg-protoporphyrin IX monomethyl ester cyclase, and the O2-dependent cyclase in ... ...

Abstract	The unique isocyclic E ring of chlorophylls contributes to their role as light-absorbing pigments in photosynthesis. The formation of the E ring is catalyzed by the Mg-protoporphyrin IX monomethyl ester cyclase, and the O2-dependent cyclase in prokaryotes consists of a diiron protein AcsF, augmented in cyanobacteria by an auxiliary subunit Ycf54. Here, we establish the composition of plant and algal cyclases, by demonstrating the in vivo heterologous activity of O2-dependent cyclases from the green alga Chlamydomonas reinhardtii and the model plant Arabidopsis thaliana in the anoxygenic photosynthetic bacterium Rubrivivax gelatinosus and in the non-photosynthetic bacterium Escherichia coli. In each case, an AcsF homolog is the core catalytic subunit, but there is an absolute requirement for an algal/plant counterpart of Ycf54, so the necessity for an auxiliary subunit is ubiquitous among oxygenic phototrophs. A C-terminal ∼40 aa extension, which is present specifically in green algal and plant Ycf54 proteins, may play an important role in the normal function of the protein as a cyclase subunit.
MeSH term(s)	Amino Acid Sequence ; Arabidopsis/enzymology ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Burkholderiales/enzymology ; Chlamydomonas reinhardtii/enzymology ; Chloroplast Proteins/genetics ; Chloroplast Proteins/metabolism ; Escherichia coli/enzymology ; Oxygen/metabolism ; Oxygenases/genetics ; Oxygenases/metabolism ; Protochlorophyllide/biosynthesis ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sequence Homology
Chemical Substances	Arabidopsis Proteins ; Chloroplast Proteins ; EMB3143 protein, Arabidopsis ; Recombinant Proteins ; Protochlorophyllide (20369-67-9) ; Oxygenases (EC 1.13.-) ; magnesium protoporphyrin monomethyl ester oxidative cyclase (EC 1.14.13.-) ; Oxygen (S88TT14065)
Language	English
Publishing date	2020-05-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2969-5
ISSN	1470-8728 ; 0006-2936 ; 0306-3275 ; 0264-6021
ISSN (online)	1470-8728
ISSN	0006-2936 ; 0306-3275 ; 0264-6021
DOI	10.1042/BCJ20200221
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uc I Zs.110: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Preparation of Al-Si alloy from silicon cutting waste: Enabling oxide surface removing and silicon utilization improving via vacuum sintering

Chen, Guangyu / Li, Yan / Huang, Liuqing / Yang, Yuanhao / Sheng, Wang / Zhang, Chentong / Luo, Xuetao

Science of the Total Environment. 2023 Mar., v. 863 p.161038-

2023

Abstract: Environmentally harmful silicon cutting waste (SCW) generated during the production of silicon solar cells possesses a high reuse value. However, the presence of oxide surface and impurities restrict the Si-cores reuse. Herein, inspired by the structure ... ...

Abstract	Environmentally harmful silicon cutting waste (SCW) generated during the production of silicon solar cells possesses a high reuse value. However, the presence of oxide surface and impurities restrict the Si-cores reuse. Herein, inspired by the structure and composition of SCW, designed a combined process consisting of vacuum sintering and alloying to reuse SCW into Al-Si alloy at a low cost. Vacuum sintering promotes the reduction of the oxide surface by Si-core. Oxygen content was decreased by 92.54 %, demonstrating the successful removal of the oxide surface. The discharge of reduction products contributes to the densification, and the Si-core has converged into dense Vac-ceramic (Si block), rendering a relative density of 96.17 %. More importantly, during the alloying process, the formation of Vac-ceramic dredges the mass transfer pathway from Si-core to Al melt. As a result, the Si utilization rate increased about seven times compared with the direct reuse of pristine SCW. Compared with commercial Al-Si alloys, the Al-Si alloys prepared by reusing silicon cutting waste in this work have satisfactory mechanical properties. The method has the prominent advantages of being protective-atmosphere-free, additive-free, and scalability, and may be a promising candidate for the silicon cutting waste purifying and reusing field.
Keywords	alloys ; environment ; mass transfer ; oxygen ; silicon ; wastes ; Harmful solid waste recycling ; Silicon cutting waste ; Oxide surface removal ; Vacuum sintering ; Al-Si alloy
Language	English
Dates of publication	2023-03
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.161038
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 74/341: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article: [Diabetes with liver disease: mechanism and management].

Chen, Guangyu

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

2014 Volume 22, Issue 3, Page(s) 171–173

MeSH term(s)	Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/therapy ; Humans ; Liver Diseases/complications ; Liver Diseases/diagnosis ; Liver Diseases/therapy
Language	Chinese
Publishing date	2014-03
Publishing country	China
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1007-3418
ISSN	1007-3418
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Distinct Functional Connectivity Patterns for Intermittent Vs Constant Neuropathic Pain Phenotypes in Persistent Spinal Pain Syndrome Type 2 Patients.

Pahapill, Peter A / Arocho-Quinones, Elsa V / Chen, Guangyu / Swearingen, Brad / Tomas, Carissa W / Koch, Kevin M / Nencka, Andrew Scott

Journal of pain research

2024 Volume 17, Page(s) 1453–1460

Abstract: Background: Chronic low back pain (cLBP) has been associated with alterations in brain functional connectivity (FC) but based upon heterogeneous populations and single network analyses. Our goal is to study a more homogeneous cLBP population and focus ... ...

Abstract	Background: Chronic low back pain (cLBP) has been associated with alterations in brain functional connectivity (FC) but based upon heterogeneous populations and single network analyses. Our goal is to study a more homogeneous cLBP population and focus on multiple cross-network (CN) connectivity analysis. We hypothesize that within this population: 1) altered CN FC, involving emotion and reward/aversion functions are related to their pain levels and 2) altered relationships are dependent upon pain phenotype (constant neuropathic vs intermittent pain). Methods: In this case series, resting state fcMRI scans were obtained over a study duration of 60 months from 23 patients (13 constant neuropathic and 10 intermittent pain) with Persistent Spinal Pain Syndrome (PSPS Type 2) being considered for spinal cord stimulation (SCS) therapy at a single academic center. Images were acquired using a Discovery MR750 GE scanner. During the resting state acquisitions, they were asked to close their eyes and relax. The CN analysis was performed on 7 brain networks and compared to age-matched controls. Linear regression was used to test the correlation between CN connectivity and pain scores. Results: CN FC involving emotion networks (STM: striatum network index) was significantly lower than controls in all patients, regardless of pain phenotype (P < 0.003). Pain levels were positively correlated with emotional FC for intermittent pain but negatively correlated for constant pain. Conclusion: This is the first report of 1) altered CN FC involving emotion/reward brain circuitry in 2) a homogeneous population of cLBP patients with 3) two different pain phenotypes (constant vs intermittent) in PSPS Type 2 patients being considered for SCS. FC patterns were altered in cLBP patients as compared to controls and were characteristic for each pain phenotype. These data support fcMRI as a potential and objective tool in assessing pain levels in cLBP patients with different pain phenotypes.
Language	English
Publishing date	2024-04-12
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2495284-9
ISSN	1178-7090
ISSN	1178-7090
DOI	10.2147/JPR.S426640
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Comparison of totally laparoscopic and laparoscopic-assisted approach in gastrectomy with D2 lymphadenectomy for advanced gastric cancer after neoadjuvant chemotherapy: a retrospective comparative study.

Chen, Zhenyu / Chen, Guangyu / Li, Yan / Kou, Sha / Wang, Tao / Zhang, Lin / Cao, Yongkuan / Liu, Liye

Annals of surgical treatment and research

2024 Volume 106, Issue 4, Page(s) 218–224

Abstract: Purpose: Neoadjuvant chemotherapy is strongly recommended for advanced gastric cancer due to good local control and a high rate of R0 dissection with this strategy. Minimally invasive techniques such as laparoscopy-assisted or total laparoscopic ... ...

Abstract	Purpose: Neoadjuvant chemotherapy is strongly recommended for advanced gastric cancer due to good local control and a high rate of R0 dissection with this strategy. Minimally invasive techniques such as laparoscopy-assisted or total laparoscopic approaches is becoming more and more acceptable in the treatment for gastric cancer. However, the safety and efficiency of total laparoscopic D2 gastrectomy (TLG) for advanced gastric cancer after neoadjuvant chemotherapy have not been well evaluated. Methods: A retrospective study in a single center from 2014 to 2016 was conducted. A total of 65 locally advanced gastric cancers were treated by laparoscopy-assisted gastrectomy (LAG) or TLG. Parameters which include operation time, blood loss, complications, hospital stay, 3-year overall survival, and 3-year disease-free survival were used for comparison. Results: The time of operation in the TLG group was shorter than in the LAG group (P = 0.013), blood loss was less (P = 0.002) and time to first flatus was shorter (P = 0.039) in the TLG group than that in the LLG group. Intraoperative and postoperative complications were comparable in both groups. No significant difference was found in 3-year overall and disease-free survival. Conclusion: For patients with locally advanced gastric cancer after neoadjuvant chemotherapy, laparoscopic D2 gastrectomy can be considered as a safe and efficient alternative. A further multicenter prospective randomized controlled study is needed to elucidate the applicability of this technique for advanced gastric cancer.
Language	English
Publishing date	2024-03-29
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	3012234-X
ISSN	2288-6796 ; 2288-6575
ISSN (online)	2288-6796
ISSN	2288-6575
DOI	10.4174/astr.2024.106.4.218
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito