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Article: Sustainable entrepreneurship out of entrepreneurial opportunity identification: The mediating role of psychological capital.

Zhang, Hongxin / Chen, Hongxia

2023 Volume 14, Page(s) 1129855

Abstract: Introduction: The aim of the present study, was to examine the simultaneous effects of entrepreneurial opportunity identification (EOI) and psychological capital (PC) on university students' entrepreneurial intention (EI). Compared with necessity-driven ...

Abstract	Introduction: The aim of the present study, was to examine the simultaneous effects of entrepreneurial opportunity identification (EOI) and psychological capital (PC) on university students' entrepreneurial intention (EI). Compared with necessity-driven entrepreneurship, opportunity-driven entrepreneurship is more sustainable. Scholars have shown that EOI is key to forming EI, but little has been discussed about its association with PC. Methods: A total of 555 university students in China were enrolled by means of convenience sampling. Descriptive statistics and correlation analysis of variables were performed using SPSS 21.0 software. Structural equation modeling analysis (SEM) with AMOS 21.0 was used to examine the structural effects of EOI and PC on university students' EI. Results: According to the results, university students' EOI and PC had a positive and insignificant influence on their levels of EI. Furthermore, PC was found to fully mediate the impact of EOI on EI. Discussion: The present study could shed light on new instructions to examine the interaction between the cognitive and psychological components of EI in the field of entrepreneurship. It is recommended that educators and practitioners should pay regard to the role of EOI and PC.
Language	English
Publishing date	2023-03-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2023.1129855
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Advances in the beneficial effects of nutrition on stroke-related Sarcopenia: A narrative review.

Gao, Zhiqiang / Chen, Hongxia

Medicine

2023 Volume 102, Issue 24, Page(s) e34048

Abstract: Stroke is one of the most common causes of disability in adults. Sarcopenia is a syndrome characterized by progressive systemic muscle loss and functional decline. The decrease in skeletal muscle mass and muscle function throughout the body after stroke ... ...

Abstract	Stroke is one of the most common causes of disability in adults. Sarcopenia is a syndrome characterized by progressive systemic muscle loss and functional decline. The decrease in skeletal muscle mass and muscle function throughout the body after stroke cannot be explained by neurological motor disorders due to brain injury alone, it is considered to be a secondary sarcopenia known as stroke-related sarcopenia. Mounting evidences showed that stroke-related sarcopenia might promote the occurrence and development of sarcopenia through various pathogenesis such as muscle atrophy, dysphagia, inflammation, and malnutrition, etc. At present, the main indicators used to assess malnutrition in patients with stroke-related sarcopenia include temporalis muscle thickness, calf circumference, phase angle, geriatric nutritional risk index and mini-nutritional assessment short-form, etc. Currently, there is no particularly effective method to curb its progression, but supplementation with essential amino acids, whey protein combined with vitamin D, high energy diet, avoiding Polypharmacy, as well as increasing physical activity level and reducing sedentary lifestyle may improve the malnutrition status of stroke patients, and increase the muscle mass and skeletal muscle index, further delay or even prevent the development of stroke-related sarcopenia. This article reviews the latest research progress on the characteristics, epidemiology, pathogenesis and the role of nutrition in stroke-related sarcopenia, so as to provide reference for the clinical treatment and rehabilitation of stroke-related sarcopenia.
MeSH term(s)	Humans ; Aged ; Sarcopenia/therapy ; Sarcopenia/complications ; Nutritional Status ; Muscle, Skeletal/physiology ; Malnutrition/therapy ; Malnutrition/complications ; Stroke/complications ; Stroke/metabolism
Language	English
Publishing date	2023-06-16
Publishing country	United States
Document type	Review ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000034048
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Article ; Online: COVID-19 victimization experience and university students' smartphone addiction: the mediating role of emotional intelligence.

Chen, Hongxia / Zhang, Hong-Xin

BMC public health

2023 Volume 23, Issue 1, Page(s) 1410

Abstract: Objectives: During the post-COVID-19 era, everyone has the risk of contracting the virus and becoming the victims of COVID-19. Examining the relationship between the COVID-19 victimization experience and its effects is more urgent. The aim of present ... ...

Abstract	Objectives: During the post-COVID-19 era, everyone has the risk of contracting the virus and becoming the victims of COVID-19. Examining the relationship between the COVID-19 victimization experience and its effects is more urgent. The aim of present study is to propose a mediation model to investigate the association between COVID-19 victimization experience and smartphone addiction, and the mediating role of emotional intelligence. Methods: A online questionnaire including the COVID-19 Victimization Experience Scale, the Smartphone Addiction Scale, and the Emotional Intelligence Scale among Chinese university students, were employed in this study. Finally, 1154 valid questionnaires were collected. The reliability and confirmatory factor analysis results showed that all three scales had good reliability and validity. Results: Structural Equation Model (SEM) demonstrated that COVID-19 victimization experience significantly predicted smartphone addiction in university students, and emotional intelligence partially mediated the association between COVID-19 victimization experience and smartphone addiction. Bootstrap results furthermore tested the rigor of the mediating effect. Conclusion: COVID-19 victimization experience was a important variables in predicting university students's martphone addiction, and emotional intelligence was a protective factor in decreasing the negative effect of COVID-19 victimization experience on addictive behaviors. It is suggested that instructors should integrate emotional intelligence training programs into mental health courses so as to improve students' emotional intelligence ability.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Internet Addiction Disorder ; Reproducibility of Results ; Universities ; Emotional Intelligence ; Students
Language	English
Publishing date	2023-07-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-023-16355-7
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Article: Comparison of different preoperative objective nutritional indices for evaluating 30-d mortality and complications after liver transplantation.

Li, Chuan / Chen, Hong-Xia / Lai, Yan-Hua

World journal of gastrointestinal surgery

2024 Volume 16, Issue 1, Page(s) 143–154

Abstract: Background: The nutritional status is closely related to the prognosis of liver transplant recipients, but few studies have reported the role of preoperative objective nutritional indices in predicting liver transplant outcomes.: Aim: To compare the ... ...

Abstract	Background: The nutritional status is closely related to the prognosis of liver transplant recipients, but few studies have reported the role of preoperative objective nutritional indices in predicting liver transplant outcomes. Aim: To compare the predictive value of various preoperative objective nutritional indicators for determining 30-d mortality and complications following liver transplantation (LT). Methods: A retrospective analysis was conducted on 162 recipients who underwent LT at our institution from December 2019 to June 2022. Results: This study identified several independent risk factors associated with 30-d mortality, including blood loss, the prognostic nutritional index (PNI), the nutritional risk index (NRI), and the control nutritional status. The 30-d mortality rate was 8.6%. Blood loss, the NRI, and the PNI were found to be independent risk factors for the occurrence of severe postoperative complications. The NRI achieved the highest prediction values for 30-d mortality [area under the curve (AUC) = 0.861, Conclusion: The NRI has good predictive value for 30-d mortality and severe complications following LT. The NRI could be an effective tool for transplant surgeons to evaluate perioperative nutritional risk and develop relevant nutritional therapy.
Language	English
Publishing date	2024-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573700-4
ISSN	1948-9366
ISSN	1948-9366
DOI	10.4240/wjgs.v16.i1.143
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Article: A case report of atypical chronic myeloid leukemia with complete hematological and major molecular response to Venetoclax/Azacitidine treatment.

Chen, Hongxia / Wang, Ning / Li, Yin / Xie, Xiaohong / Yang, Yi

Frontiers in oncology

2024 Volume 14, Page(s) 1327834

Abstract: Atypical Chronic Myeloid Leukemia (aCML), a myeloproliferative neoplasm with poor prognosis, was reclassified as aCML by the ICC classification, and as MDS/MPN with neutrophilia by the WHO 2022 classification. Due to the heterogeneity of its clinical ... ...

Abstract	Atypical Chronic Myeloid Leukemia (aCML), a myeloproliferative neoplasm with poor prognosis, was reclassified as aCML by the ICC classification, and as MDS/MPN with neutrophilia by the WHO 2022 classification. Due to the heterogeneity of its clinical features and the lack of unique biomarkers, as well as limited treatment options, aCML currently lacks a standardized treatment protocol. In this case report, we reviewed a young man diagnosed with aCML who achieved complete clinical and hematologic remission subsequent to receiving a therapeutic regimen combining Venetoclax and Azacitidine.
Language	English
Publishing date	2024-03-25
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2024.1327834
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Article: Low-Velocity Impact and Post-Impact Residual Flexural Properties of Kevlar/EP Three-Dimensional Angle-Interlock Composites.

Shi, Juanjuan / Guo, Yanwen / Huang, Xiaomei / Chen, Hongxia / Cao, Haijian

Materials (Basel, Switzerland)

2024 Volume 17, Issue 3

Abstract: In this study, five three-dimensional angle-interlock fabrics with different warp and weft densities were fabricated using 1000D Kevlar filaments. The Kevlar/EP composites were prepared by vacuum-assisted molding techniques. The low-velocity impact ... ...

Abstract	In this study, five three-dimensional angle-interlock fabrics with different warp and weft densities were fabricated using 1000D Kevlar filaments. The Kevlar/EP composites were prepared by vacuum-assisted molding techniques. The low-velocity impact property of the composite was tested, focusing on the effects of the warp and weft densities, impact energy, impactor shape, and impactor diameter. The damage area, dent depth, and crack lengths in the warp and weft direction were used to evaluate the impact performance, and the specimens were compared with plain-weave composites with similar areal densities. The dominant failure mode of the conical impactor was fiber fracture, while the dominant failure mode of the hemispherical impactor was fiber-resin debonding. The cylindrical impactor showed only minor resin fragmentation. The residual flexural strength of the composite after impact was tested to provide insights into its mechanical properties. The study findings will provide a theoretical basis for the optimization of the design of impact-resistant structures using such materials and facilitate their engineering applications.
Language	English
Publishing date	2024-01-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma17030681
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Article ; Online: Sunlight propelled two-dimensional nanorobots with enhanced mechanical damage of bacterial membrane

Mao, Zhihui / Peng, Xinsheng / Chen, Hongxia

Water Research. 2023 May, v. 235 p.119900-

2023

Abstract: Bacterial pollution in water sources poses a serious threat to human health and causes a water crisis. To treat it efficiently and ecologically, many studies have explored the antibacterial properties of two-dimensional nanomaterials in water, but their ... ...

Abstract	Bacterial pollution in water sources poses a serious threat to human health and causes a water crisis. To treat it efficiently and ecologically, many studies have explored the antibacterial properties of two-dimensional nanomaterials in water, but their static antibacterial modes limit their effectiveness. In this work, we designed a facile and effective antibacterial nanorobots by loading super small gold nanorods (sAuNR) onto the surface of MXene nanosheets (MXene@sAuNR). The plasmon resonance effect of sAuNR can enhance the optical absorption cross section of the nanorobots, thereby improving their motion ability under irradiation and then causing cell membrane mechanical damage to bacteria. Our research proved that nanorobots with good optical driving characteristics displayed gratifying antibacterial properties even at ultra-low concentration as 5 µg/mL within 30 min. Furthermore, the nanorobots showed satisfactory antibacterial efficiency in real river samples under sunlight irradiation. These nanorobots presented in this study provides valuable insights towards designing self-energy collection and self-driving antibacterial materials that overcome the shortcomings of conventional static antibacterial methods. As sunlight is the cheapest and natural light source, these nanorobots have opened an effective and sustainable way for large-scale treatment of bacterial pollution in water.
Keywords	absorption ; cell membranes ; gold ; human health ; irradiation ; mechanical damage ; nanorods ; nanosheets ; pollution ; research ; rivers ; solar radiation ; water ; Antibacterial nanorobots ; MXene nanosheets ; Optical driving
Language	English
Dates of publication	2023-05
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	202613-2
ISSN	1879-2448 ; 0043-1354
ISSN (online)	1879-2448
ISSN	0043-1354
DOI	10.1016/j.watres.2023.119900
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Silver nanoparticles deposited on a cotton fabric surface

Chen, Hongxia / Zhang, Guangyu / Zhang, Wei / Gao, Weidong

RSC advances

2023 Volume 13, Issue 17, Page(s) 11450–11456

Abstract: This study introduces a new method for the synthesis of silver nanoparticles on a cotton fabric surface by ... ...

Abstract	This study introduces a new method for the synthesis of silver nanoparticles on a cotton fabric surface by an
Language	English
Publishing date	2023-04-12
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d3ra00989k
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Article: SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA.

Zhang, Qi / Hao, Rongjiao / Chen, Hongxia / Zhou, Gangqiao

Cell death discovery

2023 Volume 9, Issue 1, Page(s) 319

Abstract: Human single-stranded DNA-binding protein homologs hSSB1 (SOSSB1) and hSSB2 (SOSSB2) make a vital impact on maintaining genome stability as the B subunits of the sensor of single-stranded DNA complex (SOSS). However, whether and how SOSSB1 and SOSSB2 ... ...

Abstract	Human single-stranded DNA-binding protein homologs hSSB1 (SOSSB1) and hSSB2 (SOSSB2) make a vital impact on maintaining genome stability as the B subunits of the sensor of single-stranded DNA complex (SOSS). However, whether and how SOSSB1 and SOSSB2 modulate mutual expression is unclear. This study, demonstrated that the depletion of SOSSB1 in cells enhances the stability of the SOSSB2 protein, and conversely, SOSSB2 depletion enhances the stability of the SOSSB1 protein. The levels of SOSSB1 and SOSSB2 proteins are mutually regulated through their competitive binding with SOSSA which associates with the highly conservative OB-fold domain in SOSSB1 and SOSSB2. The destabilized SOSSB1 and SOSSB2 proteins can be degraded via the proteasome pathway. Additionally, the simultaneous loss of SOSSB1 and SOSSB2 aggravates homologous recombination (HR)-mediated DNA repair defects, enhances cellular radiosensitivity and promotes cell apoptosis. In conclusion, in this study, we showed that SOSSB1 and SOSSB2 positively regulate HR repair and the interaction between SOSSA and SOSSB1 or SOSSB2 prevents the degradation of SOSSB1 and SOSSB2 proteins via the proteasome pathway.
Language	English
Publishing date	2023-08-28
Publishing country	United States
Document type	Journal Article
ISSN	2058-7716
ISSN	2058-7716
DOI	10.1038/s41420-023-01619-3
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Article ; Online: Huatanmaitong tablet alleviate cerebral ischemic reperfusion injury with hyperlipidaemia in rats by regulating OATPs/VEGF axis.

Sun, Shuangxi / Wang, Qi / Chen, Hongxia / Pan, Ruihuan

Cellular and molecular biology (Noisy-le-Grand, France)

2023 Volume 69, Issue 13, Page(s) 235–240

Abstract: Stroke is the top priority pathogenesis of disability and death globally, affecting people worldwide. The presence of high levels of lipids in the blood has been confirmed as a vital factor of ischemic stroke. We aim to examine the effectiveness of ... ...

Abstract	Stroke is the top priority pathogenesis of disability and death globally, affecting people worldwide. The presence of high levels of lipids in the blood has been confirmed as a vital factor of ischemic stroke. We aim to examine the effectiveness of Huatanmaitong tablet in hyperlipidemia rats that have experienced an ischemic stroke. We created a rat model of middle cerebral artery occlusion (MCAO) with hyperlipidemia as a basis. Following 8 weeks of high-fat diet, the model rats underwent MCAO surgery. Subsequently, the rats were administered huatanmaitong tablets and lipitor tablets as treatments. Therefore there are five groups, CONTROL, MCAO, hyperlipidemia (HLP), Huatanmaitong tablet (HTMTT) and Lipitor (LIPITOR) groups respective ly. To assess the efficacy of the medication, the serum lipid levels of rats were measured both prior to and following administration. Hematoxylin eosin staining was used to observe the alterations in the brain and liver structures within each group. VEGF and OATPs related factors were detected in brain, liver by using immunohistochemistry, Western blotting, and Quantitative PCR. After the model was established successfully, the infarct volume and behavioral scores of the model group, hyperlipidemia group, Huatan Maitong tablet group and Lipitor group had statistical differences (P<0.05). Blood lipid levels of rats were measured before and after treatment, and it was found that Huatanmaitong tablets effectively reduced these levels. Hematoxylin and eosin staining of the brain and liver showed that huatanmaitong tablets maintained the microstructure stability. Western blotting and real-time PCR revealed that Huatanmaitong tablets improved the expression level of organic anion transport (OATP1B1, OATP2B1) in rat tissues with ischemic stroke, enhancing the transmembrane transport of exogenous substances and maintaining homeostatic balance. Additionally, it down-regulated the expression of VEGF in various organs such as the brain, and liver, demonstrating the ability of Huatanmaitong tablets to remove phlegm, blood stasis, and promote circulation by regulating serum lipid levels, organic anion transport peptide, and VEGF in rats. The behavioral score of ischemic stroke rats can be improved and the neurological impairment symptoms of rats can be alleviated by Huatanmaitong tablet through the regulation of OATPS/VEGF axis.
MeSH term(s)	Animals ; Rats ; Anions ; Atorvastatin/pharmacology ; Hyperlipidemias/drug therapy ; Infarction, Middle Cerebral Artery/drug therapy ; Ischemic Stroke/drug therapy ; Rats, Sprague-Dawley ; Reperfusion Injury/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Drugs, Chinese Herbal/pharmacology
Chemical Substances	Anions ; Atorvastatin (A0JWA85V8F) ; Vascular Endothelial Growth Factor A ; Drugs, Chinese Herbal
Language	English
Publishing date	2023-12-10
Publishing country	France
Document type	Journal Article
ZDB-ID	1161779-2
ISSN	1165-158X ; 0145-5680
ISSN (online)	1165-158X
ISSN	0145-5680
DOI	10.14715/cmb/2023.69.13.35
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