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  1. Article: Changes in peripheral blood T lymphocyte subsets predict disease progression in patients with rheumatoid arthritis.

    Tan, Jie / Chen, Jialiang

    American journal of translational research

    2022  Volume 14, Issue 2, Page(s) 1068–1075

    Abstract: Objective: To explore the correlation between abnormal changes in peripheral blood T lymphocyte subsets and disease progression in patients with active rheumatoid arthritis (RA).: Methods: This is a retrospective study, in which 53 patients with ... ...

    Abstract Objective: To explore the correlation between abnormal changes in peripheral blood T lymphocyte subsets and disease progression in patients with active rheumatoid arthritis (RA).
    Methods: This is a retrospective study, in which 53 patients with active RA were selected as the study subjects and 50 healthy people were selected as the control group. Lymphocyte subsets were determined in both arms. According to whether CD4/CD8 ratio increased, RA patients were subdivided into an elevated CD4/CD8 group and a non-elevated CD4/CD8 group, and compared to the control group. The risk factors affecting the disease progression of patients with active RA were analyzed.
    Results: CD4
    Conclusions: When an autoimmune disorder occurs in patients with active RA, CD8
    Language English
    Publishing date 2022-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A quantitative method for in situ pump-beam metrology in 4D ultrafast electron microscopy.

    Chen, Jialiang / Flannigan, David J

    Ultramicroscopy

    2022  Volume 234, Page(s) 113485

    Abstract: We report a method for measuring spot size and focusing conditions of the femtosecond (fs) excitation laser in situ at the specimen location in 4D ultrafast electron microscopy (UEM). The method makes use of threshold laser ablation behaviors of thin ... ...

    Abstract We report a method for measuring spot size and focusing conditions of the femtosecond (fs) excitation laser in situ at the specimen location in 4D ultrafast electron microscopy (UEM). The method makes use of threshold laser ablation behaviors of thin amorphous carbon membranes. For Gaussian beam profiles and for ablation threshold fluence values, we analytically derive expressions describing the relationship between ablated hole size and the actual laser spot size. Using these expressions, we developed experimental procedures for characterizing the shape and spot size of the pump beam at the specimen. We demonstrate the viability of the approach for incident excitation wavelengths of 343 nm and 515 nm, thus illustrating the applicability of the method to a range of optical wavelengths without modification. Further, we show that by measuring ablated hole size as a function of focusing condition, a full metrological characterization of the Gaussian beam propagation properties can be performed. Finally, we find good agreement for spot sizes determined with this method and with those determined by extrapolation from measurements taken outside the microscope column. Overall, this method is a simple, cost-effective means for accurate and precise determination of key pump-beam parameters in situ at the specimen location in UEM experiments.
    Language English
    Publishing date 2022-02-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1479043-9
    ISSN 1879-2723 ; 0304-3991
    ISSN (online) 1879-2723
    ISSN 0304-3991
    DOI 10.1016/j.ultramic.2022.113485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Curative effect of anti-fibrosis Chinese patent medicines combined with ursodeoxycholic acid for primary biliary cholangitis: A systematic review and meta-analysis.

    Bi, Yufei / Shi, Ke / Chen, Jialiang / Wang, Xianbo

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1159222

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2023-03-21
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1159222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Case Report of a Chronic Wound Due to Venous Insufficiency Following a Traumatic Arteriovenous Fistula.

    Chen, Jialiang / Chebli, Louis

    Open journal of clinical diagnostics

    2021  Volume 11, Issue 2, Page(s) 47–51

    Abstract: Chronic lower limb wounds are common. They can be of arterial or venous origin. In this article, we will present a clinical case of a 30-year-old patient with a chronic injury to the right medial malleolus. In his history, we can note a gunshot wound to ... ...

    Abstract Chronic lower limb wounds are common. They can be of arterial or venous origin. In this article, we will present a clinical case of a 30-year-old patient with a chronic injury to the right medial malleolus. In his history, we can note a gunshot wound to the right leg. Ultrasonography and CT angiography helped in the diagnosis of traumatic arteriovenous fistula. The patient underwent a fistula embolization which allowed the wound to heal. The clinical presentation, additional examinations and the latest treatment recommendations will be discussed in this article.
    Language English
    Publishing date 2021-06-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2667293-5
    ISSN 2162-5824 ; 2162-5816
    ISSN (online) 2162-5824
    ISSN 2162-5816
    DOI 10.4236/ojcd.2021.112003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Correction to "Site-Specific Tagging of Proteins with Paramagnetic Ions for Determination of Protein Structures in Solution and in Cells".

    Su, Xun-Cheng / Chen, Jia-Liang

    Accounts of chemical research

    2021  Volume 54, Issue 24, Page(s) 4596

    Language English
    Publishing date 2021-12-02
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1483291-4
    ISSN 1520-4898 ; 0001-4842
    ISSN (online) 1520-4898
    ISSN 0001-4842
    DOI 10.1021/acs.accounts.1c00702
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  6. Article: Interfacial Polarization Control Engineering and Ferroelectric PZT/Graphene Heterostructure Integrated Application.

    Bi, Kaixi / Han, Shuqi / Chen, Jialiang / Bi, Xiaoxue / Yang, Xiangyu / Niu, Liya / Mei, Linyu

    Nanomaterials (Basel, Switzerland)

    2024  Volume 14, Issue 5

    Abstract: Integration and miniaturization are the inevitable trends in the development of electronic devices. PZT and graphene are typical ferroelectric and carbon-based materials, respectively, which have been widely used in various fields. Achieving high-quality ...

    Abstract Integration and miniaturization are the inevitable trends in the development of electronic devices. PZT and graphene are typical ferroelectric and carbon-based materials, respectively, which have been widely used in various fields. Achieving high-quality PZT/graphene heterogeneous integration and systematically studying its electrical properties is of great significance. In this work, we reported the characterization of a PZT film based on the sol-gel method. Additionally, the thickness of the PZT film was pushed to the limit size (~100 nm) by optimizing the process. The test results, including the remnant and leakage current, show that the PZT film is a reliable and suitable platform for further graphene-integrated applications. The non-destructive regulation of the electrical properties of graphene has been studied based on a domain-polarized substrate and strain-polarized substrate. The domain structures in the PZT film exhibit different geometric structures with ~0.3 V surface potential. The I-V output curves of graphene integrated on the surface of the PZT film exhibited obvious rectification characteristics because of p/n-doping tuned by an interfacial polarized electric field. In contrast, a ~100 nm thick PZT film makes it easy to acquire a larger strain gradient for flexural potential. The tested results also show a rectification phenomenon, which is similar to domain polarization substrate regulation. Considering the difficulty of measuring the flexural potential, the work might provide a new approach to assessing the flexural polarized regulation effect. A thinner ferroelectric film/graphene heterojunction and the polarized regulation of graphene will provide a platform for promoting low-dimension film-integrated applications.
    Language English
    Publishing date 2024-02-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano14050432
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  7. Article ; Online: Associations between serum testosterone levels and overactive bladder in women: a cross-sectional research of NHANES 2011 to 2016.

    Li, Wenshuang / Huang, Junlong / Chen, Jialiang / Zhang, Chi / Luo, Ruixiang / Liu, Bolong / Zhou, Xiangfu

    International urology and nephrology

    2024  

    Abstract: Purpose: Androgen receptors are expressed in the pelvic floor and lower urinary tract. However, the association between serum testosterone and overactive bladder (OAB) in women remains unclear. This study aimed to investigate their association in a ... ...

    Abstract Purpose: Androgen receptors are expressed in the pelvic floor and lower urinary tract. However, the association between serum testosterone and overactive bladder (OAB) in women remains unclear. This study aimed to investigate their association in a nationally representative population.
    Methods: In this cross-sectional study, we collected data on female participants older than 20 years with serum total testosterone measurements and OAB questionnaires from the 2011-2016 National Health and Nutrition Examination Survey (NHANES). Survey-weighted logistic regression models were used to analyze the relationship between testosterone and OAB in women.
    Results: Data on 4991 women was analyzed in this study, of whom 25.9% had OAB symptoms. Women with lower serum testosterone had an increased frequency of urge urinary incontinence and nocturia compared to participants with enough testosterone. The multivariate logistic models showed that those women with a testosterone level less than 18.5 ng/dL had significantly higher odds of OAB compared to those with a testosterone level greater than 18.5 ng/dL [OR 95% CI = 1.271 (1.073-1.505), P = 0.0076]. Separate interaction analyses revealed no significant effect of age, BMI, diabetes, education, alcohol use and menopause on the association between serum testosterone and OAB. Sensitivity analyses demonstrated that additional variables (depression, stroke and stress urinary incontinence) had no significant effect on this relationship.
    Conclusions: Low serum testosterone is associated with an increased likelihood of OAB in women. This supports the potential therapeutic role of testosterone supplementation in women with OAB. Given the direct and indirect effects of testosterone on the pelvic floor and lower urinary tract, a potential mechanism for this relationship can be further explored in translational studies.
    Language English
    Publishing date 2024-03-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 204048-7
    ISSN 1573-2584 ; 0301-1623 ; 0042-1162
    ISSN (online) 1573-2584
    ISSN 0301-1623 ; 0042-1162
    DOI 10.1007/s11255-024-03996-9
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  8. Article ; Online: Building structure-borne noise measurements and estimation due to train operations in tunnel.

    Li, Xuming / Chen, Yekai / Zou, Chao / Wang, Hao / Zheng, Bokai / Chen, Jialiang

    The Science of the total environment

    2024  Volume 926, Page(s) 172080

    Abstract: The perception of structure-borne noise is particularly salient when train passes through the tunnel under the buildings, which has a negative impact on human health. In the process of constructing buildings along metro lines, it is crucial to estimate ... ...

    Abstract The perception of structure-borne noise is particularly salient when train passes through the tunnel under the buildings, which has a negative impact on human health. In the process of constructing buildings along metro lines, it is crucial to estimate indoor structure-borne noise levels in order to enhance design and prevent any negative impact on human comfort. This study conducted measurements of structure-borne noise, reverberation time, and train-induced vibrations in Guangzhou, China to investigate the generation, propagation, and dissipation mechanisms of structure-borne noise. An approach based on Short-Time Fourier Transform and Schroeder integral was proposed for obtaining frequency-dependent reverberation time. Additionally, a deep learning-based approach incorporating indoor vibrations, frequency-dependent reverberation time, and room parameters as inputs was proposed based on Genetic Algorithm-Artificial Neural Network. The estimated structure-borne noise levels demonstrated good agreement with measured values, indicating the feasibility of the approach. The finding of this research facilitates a clear comprehension of the generation, distribution, and dissipation mechanisms of indoor structure-borne noise for engineers while also enabling convenient acquisition of indoor structure-borne noise. The estimated noise levels can be effectively utilized during building design processes along metro lines to mitigate adverse impacts on human comfort.
    Language English
    Publishing date 2024-03-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.172080
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  9. Article ; Online: Effective assessment of lanthanide ion delivery into live cells by paramagnetic NMR spectroscopy.

    Chen, Jia-Liang / Yang, Yin / Shi, Tiesheng / Su, Xun-Cheng

    Chemical communications (Cambridge, England)

    2023  Volume 59, Issue 70, Page(s) 10552–10555

    Abstract: We report an effective assessment of lanthanide ion ( ... ...

    Abstract We report an effective assessment of lanthanide ion (Ln
    MeSH term(s) Lanthanoid Series Elements/chemistry ; Magnetic Resonance Spectroscopy/methods ; Proteins/chemistry ; Ions ; Indicators and Reagents
    Chemical Substances Lanthanoid Series Elements ; Proteins ; Ions ; Indicators and Reagents
    Language English
    Publishing date 2023-08-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc03135g
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  10. Article: Nonlinear correlation between fatty liver index and carotid intima media thickness among individuals undergoing health examination.

    Zhou, Yuanchen / Duan, Shaojie / Wang, Rongrui / Chen, Jialiang / Yao, Shukun

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1120581

    Abstract: Background: Fatty liver index (FLI) is a predictor of non-alcohol fatty liver disease (NAFLD). This study aimed to assess the association between FLI and carotid intima media thickness (CIMT).: Methods: In this cross-sectional study, we enrolled 277 ... ...

    Abstract Background: Fatty liver index (FLI) is a predictor of non-alcohol fatty liver disease (NAFLD). This study aimed to assess the association between FLI and carotid intima media thickness (CIMT).
    Methods: In this cross-sectional study, we enrolled 277 individuals for health examination from the China-Japan Friendship Hospital. Blood sampling and ultrasound examinations were conducted. Multivariate logistic regression and restricted cubic spline analyses were performed to evaluate the association between FLI and CIMT.
    Results: Overall, 175 (63.2%) and 105 (37.9%) individuals had NAFLD and CIMT, respectively. The multivariate logistic regression analyses results showed that high FLI was independently associated with a high risk of increased CIMT, T2 vs. T1 (odds ratio [OR], 95% confidence interval [CI]): 2.41, 1.10-5.25, p = 0.027; T3 vs. T1 (OR, 95% CI): 1.58, 0.68-3.64, p = 0.285. The association between FLI and increased CIMT exhibited a J-shaped curve (nonlinear, p = 0.019). In the threshold analysis, the OR for developing increased CIMT was 1.031 (95% CI: 1.011-1.051, p = 0.0023) in participants with FLI < 64.247.
    Conclusion: The relationship between FLI and increased CIMT in the health examination population is J-shaped, with an inflection point of 64.247.
    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease/diagnostic imaging ; Non-alcoholic Fatty Liver Disease/epidemiology ; Carotid Intima-Media Thickness ; Risk Factors ; Cross-Sectional Studies ; China/epidemiology
    Language English
    Publishing date 2023-03-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1120581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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