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  1. Article ; Online: ASO Author Reflections: The Challenging Journey from cCR to pCR After Neoadjuvant Treatment for Esophageal Squamous Cell Carcinoma.

    Chen, Ke-Neng

    Annals of surgical oncology

    2024  

    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-024-15035-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4042: Show issues Location:
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  2. Article ; Online: Factors to Consider in Surgical Resection of Pulmonary Metastatic Carcinoma.

    Chen, Ke-Neng

    Annals of surgical oncology

    2023  Volume 30, Issue 3, Page(s) 1297–1298

    MeSH term(s) Humans ; Lung Neoplasms/surgery ; Lung Neoplasms/secondary ; Carcinoma, Renal Cell/surgery ; Kidney Neoplasms/surgery ; Pneumonectomy
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Editorial
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-022-13059-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Advances in Understanding Marine Heatwaves and Their Impacts

    Oliver, Eric C. J. / Wernberg, Thomas / Benthuysen, Jessica / Chen, Ke

    2020  

    Keywords Science: general issues ; Oceanography (seas) ; marine heatwaves ; extreme events ; ocean and atmosphere interactions ; marine ecosystems ; marine resources ; climate change ; climate variability ; climate prediction
    Size 1 electronic resource (314 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231442
    ISBN 9782889636976 ; 2889636976
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: C and G are frequently mutated into T and A in coding regions of human genes.

    Wang, Yong / Chen, Ke-Ping

    Molecular genetics and genomics : MGG

    2024  Volume 299, Issue 1, Page(s) 23

    Abstract: Nucleotide mutations in human genes have long been a hot subject for study because some of them may lead to severe human diseases. Understanding the general mutational process and evolutionary trend of human genes could help answer such questions as why ... ...

    Abstract Nucleotide mutations in human genes have long been a hot subject for study because some of them may lead to severe human diseases. Understanding the general mutational process and evolutionary trend of human genes could help answer such questions as why certain diseases occur and what challenges we face in protecting human health. In this study, we conducted statistics on 89,895 single-nucleotide variations identified in coding regions of 18,339 human genes. The results show that C and G are frequently mutated into T and A in human genes. C/G (C or G)-to-T/A mutations lead to reduction of hydrogen bonds in double-stranded DNA because C-G and T-A base pairs are maintained by three and two hydrogen bonds respectively. C-to-T and G-to-A mutations occur predominantly in human genes because they not only reduce hydrogen bonds but also belong to transition mutation. Reduction of hydrogen bonds could reduce energy consumption not only in separating double strands of mutated DNA for transcription and replication but also in disrupting stem-loop structure of mutated mRNA for translation. It is thus considered that to reduce hydrogen bonds (and thus to reduce energy consumption in gene expression) is one of the driving forces for nucleotide mutation. Moreover, codon mutation is positively correlated to its content, suggesting that most mutations are not targeted on changing any specific codons (amino acids) but are merely for reducing hydrogen bonds. Our study provides an example of utilizing single-nucleotide variation data to infer evolutionary trend of human genes, which can be referenced to conduct similar studies in other organisms.
    MeSH term(s) Humans ; Mutation ; DNA/genetics ; Codon ; Biological Evolution ; Nucleotides/genetics
    Chemical Substances DNA (9007-49-2) ; Codon ; Nucleotides
    Language English
    Publishing date 2024-03-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2044817-X
    ISSN 1617-4623 ; 1617-4615
    ISSN (online) 1617-4623
    ISSN 1617-4615
    DOI 10.1007/s00438-024-02118-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1198: Show issues Location:
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  5. Thesis ; Online: Ecosystem service benefits in a perennial fruit crop

    Chen, Ke

    how do insect pollinators, arbuscular mycorrhizal fungi and soil organic matter shape raspberry production?

    2022  

    Abstract: Future agriculture faces a twofold challenge: increasing yields to safeguard food security while simultaneously reducing its environmental impact. Ecological intensification has been proposed as a solution to this challenge. It entails the integration of ...

    Abstract Future agriculture faces a twofold challenge: increasing yields to safeguard food security while simultaneously reducing its environmental impact. Ecological intensification has been proposed as a solution to this challenge. It entails the integration of ecosystem service management into farming practices to enhance or maintain yields while minimizing artificial inputs and environmental externalities. An increasing number of empirical studies have shown beneficial effects of ecosystem services on crop production, but the majority of these studies have focused on the effects of only a single ecosystem service in isolation. In contrast, in real-world agricultural systems, crop yield is shaped by several ecosystem services simultaneously. These different ecosystem services may interact (positively or negatively) and their interactions may furthermore depend on agricultural management practices. To assess the potential of ecological intensification in promoting yields and reducing external inputs, it is essential to understand the combined effects of different ecosystem services on agricultural production. The aim of this thesis was to examine whether and to what extent different ecosystem services interactively shape crop yield, and whether and how this is affected by agricultural management. Focusing on raspberry (Rubus idaeus L.), a globally important perennial fruit crop, I examined the potential interactive effects of the ecosystem services provided by insect pollinators, arbuscular mycorrhizal fungi (AMF) and soil organic matter (SOM) on the quantity and quality of raspberry production, and whether these effects were influenced by artificial fertilizer inputs.Natural relatives of commercial raspberry are widespread in temperate forests. These natural relatives depend entirely on several ecosystem services for survival and reproduction. Therefore, investigating the effects of ecosystem services on natural raspberry production would be informative to fully understand their importance, and could act as a ...
    Keywords Life Science
    Subject code 630
    Language English
    Publisher Wageningen University
    Publishing country nl
    Document type Thesis ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Use of Gerontechnology to Assist Older Adults to Cope with the COVID-19 Pandemic.

    Chen, Ke

    Journal of the American Medical Directors Association

    2020  Volume 21, Issue 7, Page(s) 983–984

    MeSH term(s) Adaptation, Psychological ; Aged ; Attitude to Computers ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Health Services Accessibility ; Humans ; Internet ; Long-Term Care ; Nursing Homes ; Pandemics ; Pneumonia, Viral/epidemiology ; Robotics/instrumentation ; SARS-CoV-2 ; Self Care ; Social Isolation/psychology ; Telemedicine ; Video Games ; Wearable Electronic Devices
    Keywords covid19
    Language English
    Publishing date 2020-05-21
    Publishing country United States
    Document type Letter
    ZDB-ID 2171030-2
    ISSN 1538-9375 ; 1525-8610
    ISSN (online) 1538-9375
    ISSN 1525-8610
    DOI 10.1016/j.jamda.2020.05.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5971: Show issues Location:
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  7. Article ; Online: Why do older people love and hate assistive technology? ‒ an emotional experience perspective.

    Chen, Ke

    Ergonomics

    2020  Volume 63, Issue 12, Page(s) 1463–1474

    Abstract: Assistive technology is increasingly valued to support older people with functional decline and disabilities. Inspired by classical theories on technology acceptance, emotional experience, and psychological needs, this study aimed to better understand ... ...

    Abstract Assistive technology is increasingly valued to support older people with functional decline and disabilities. Inspired by classical theories on technology acceptance, emotional experience, and psychological needs, this study aimed to better understand the use of assistive technology by older people. Qualitative semi-structured interviews were conducted with 50 community-dwelling older adults in Hong Kong (mean age = 67.47, standard deviation = 7.96). Thematic analysis was used to generate themes. Positive and negative emotional experiences emerged as two themes. The theme of positive emotional experiences is associated with enhanced security, independence, and relativeness. However, assistive technology may also produce anxiety, frustration, stigma, isolation, and risks that induce negative emotional experiences. These findings indicate that older users' emotional and psychological concerns should be addressed and reflected in the process of assistive technology product design and implementation.
    MeSH term(s) Aged ; Aged, 80 and over ; Disabled Persons/psychology ; Emotions ; Female ; Humans ; Independent Living ; Male ; Middle Aged ; Qualitative Research ; Self-Help Devices
    Language English
    Publishing date 2020-08-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1920-3
    ISSN 1366-5847 ; 0014-0139
    ISSN (online) 1366-5847
    ISSN 0014-0139
    DOI 10.1080/00140139.2020.1808714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Chinese Expert Consensus on Clinical Application of Oral Ginkgo biloba Preparations (2020).

    Chen, Ke-Ji

    Chinese journal of integrative medicine

    2021  Volume 27, Issue 3, Page(s) 163–169

    MeSH term(s) China ; Consensus ; Ginkgo biloba ; Plant Extracts/therapeutic use
    Chemical Substances Plant Extracts
    Language English
    Publishing date 2021-01-09
    Publishing country China
    Document type Journal Article
    ZDB-ID 2171254-2
    ISSN 1993-0402 ; 1672-0415
    ISSN (online) 1993-0402
    ISSN 1672-0415
    DOI 10.1007/s11655-021-3289-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5823: Show issues Location:
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  9. Article ; Online: Commentary: The debate between surgery and stereotactic body radiation therapy in treatment of early non-small cell lung cancer: A new connotation is needed for an old topic.

    Chen, Ke-Neng

    JTCVS open

    2021  Volume 9, Page(s) 264–267

    Language English
    Publishing date 2021-10-05
    Publishing country Netherlands
    Document type Editorial
    ISSN 2666-2736
    ISSN (online) 2666-2736
    DOI 10.1016/j.xjon.2021.09.045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Commentary: Pay Attention to the Comprehensive Prevention of Acute Lung Injury after Esophagectomy.

    Chen, Ke-Neng

    Seminars in thoracic and cardiovascular surgery

    2021  Volume 34, Issue 2, Page(s) 747–749

    MeSH term(s) Acute Lung Injury/diagnosis ; Acute Lung Injury/etiology ; Acute Lung Injury/prevention & control ; Esophageal Neoplasms/surgery ; Esophagectomy/adverse effects ; Humans ; Treatment Outcome
    Language English
    Publishing date 2021-05-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1038278-1
    ISSN 1532-9488 ; 1043-0679
    ISSN (online) 1532-9488
    ISSN 1043-0679
    DOI 10.1053/j.semtcvs.2021.04.041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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