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  1. Book: Special issue: Food safety in China

    Chen, Kevin Z.

    (Journal of integrative agriculture ; Vol. 14, No. 11 (2015))

    2015  

    Title variant Food safety in China
    Author's details Kevin Chen, guest editor of JIA, International Food Policy Research Institute (IFPRI)
    Series title Journal of integrative agriculture ; Vol. 14, No. 11 (2015)
    Collection
    Language English
    Size Seite 2137-2400, Illustrationen, Diagramme, Karten
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT019313634
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  2. Book: Earthquake lessons from China

    Chen, Kevin Z. / Zhang, Qiang / Hsu, Claire

    coping and rebuilding strategies

    2016  

    Author's details edited by Kevin Z. Chen, Qiang Zhang, and Claire Hsu
    Language English
    Size xiv, 144 Seiten, Illustrationen
    Publisher International Food Policy Research Institute
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index. - A peer-reviewed publication. - Enthält 6 Beiträge
    HBZ-ID HT018988695
    ISBN 978-0-89629-874-3 ; 0-89629-874-4
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  3. Article ; Online: Optimal Population Coding for Dynamic Input by Nonequilibrium Networks.

    Chen, Kevin S

    Entropy (Basel, Switzerland)

    2022  Volume 24, Issue 5

    Abstract: The efficient coding hypothesis states that neural response should maximize its information about the external input. Theoretical studies focus on optimal response in single neuron and population code in networks with weak pairwise interactions. However, ...

    Abstract The efficient coding hypothesis states that neural response should maximize its information about the external input. Theoretical studies focus on optimal response in single neuron and population code in networks with weak pairwise interactions. However, more biological settings with asymmetric connectivity and the encoding for dynamical stimuli have not been well-characterized. Here, we study the collective response in a kinetic Ising model that encodes the dynamic input. We apply gradient-based method and mean-field approximation to reconstruct networks given the neural code that encodes dynamic input patterns. We measure network asymmetry, decoding performance, and entropy production from networks that generate optimal population code. We analyze how stimulus correlation, time scale, and reliability of the network affect optimal encoding networks. Specifically, we find network dynamics altered by statistics of the dynamic input, identify stimulus encoding strategies, and show optimal effective temperature in the asymmetric networks. We further discuss how this approach connects to the Bayesian framework and continuous recurrent neural networks. Together, these results bridge concepts of nonequilibrium physics with the analyses of dynamics and coding in networks.
    Language English
    Publishing date 2022-04-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e24050598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: An Improved A* Search Algorithm for Road Networks Using New Heuristic Estimation

    Chen, Kevin Y.

    2022  

    Abstract: Finding the shortest path between two points in a graph is a fundamental problem that has been well-studied over the past several decades. Shortest path algorithms are commonly applied to modern navigation systems, so our study aims to improve the ... ...

    Abstract Finding the shortest path between two points in a graph is a fundamental problem that has been well-studied over the past several decades. Shortest path algorithms are commonly applied to modern navigation systems, so our study aims to improve the efficiency of an existing algorithm on large-scale Euclidean networks. The current literature lacks a deep understanding of certain algorithms' performance on these types of networks. Therefore, we incorporate a new heuristic function, called the $k$-step look-ahead, into the A* search algorithm and conduct a computational experiment to evaluate and compare the results on road networks of varying sizes. Our main findings are that this new heuristic yields a significant improvement in runtime, particularly for larger networks when compared to standard A*, as well as that a higher value of $k$ is needed to achieve optimal efficiency as network size increases. Future research can build upon this work by implementing a program that automatically chooses an optimal $k$ value given an input network. The results of this study can be applied to GPS routing technologies or other navigation devices to speed up the time needed to find the shortest path from an origin to a destination, an essential objective in daily life.

    Comment: 12 pages, 9 figures, submitted to ALENEX 2023
    Keywords Computer Science - Data Structures and Algorithms
    Subject code 000
    Publishing date 2022-07-30
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: A Case of Postpartum Obsessive-Compulsive Disorder in a First-Time Father.

    Chen, Kevin W / Schultz, Luke / Hughes, Neil

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54547

    Abstract: Obsessive-Compulsive Disorder (OCD) is a well-recognized psychiatric condition characterized by distressing obsessions and compulsions. While the perinatal period is a known trigger for OCD in women, less attention has been given to its occurrence in men, ...

    Abstract Obsessive-Compulsive Disorder (OCD) is a well-recognized psychiatric condition characterized by distressing obsessions and compulsions. While the perinatal period is a known trigger for OCD in women, less attention has been given to its occurrence in men, particularly new fathers. This case report examines the unique presentation of postpartum-onset OCD (ppOCD) in a first-time father. A 33-year-old father presented eight months after the birth of his first child with distressing intrusive thoughts related to harming his eight-month-old daughter. These thoughts were ego-dystonic, causing significant distress, and led to a rapid deterioration in his mental health. Intrusive thoughts included a desire to leave his daughter in a busy street and place her in a hot oven. The patient became severely depressed, experienced significant weight loss, and was unable to perform daily activities of living. He repeatedly denied any intent to act on these thoughts. Following a visit to the ED, the patient was admitted to a psychiatric facility and started on escitalopram and aripiprazole. Approximately one month post-discharge, the patient reported significant symptom improvement, and after two months, his symptoms were well-controlled. He was successfully tapered off aripiprazole due to remission of symptoms and adverse effects. This case report highlights the need for greater awareness and screening of ppOCD in both men and women during the perinatal period. Utilizing existing screening tools and well-established pharmacological treatments for OCD can significantly improve the recognition and management of this distressing disorder in fathers, ultimately improving their quality of life and that of their families. Further research is needed to better understand the prevalence and specific management of male ppOCD.
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54547
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Alcohol-associated liver disease and the COVID-19 pandemic in New Zealand-a single centre retrospective analysis.

    Chen, Kevin Yy / Wang, Michael Tm / Schauer, Cameron

    The New Zealand medical journal

    2024  Volume 137, Issue 1593, Page(s) 99–104

    MeSH term(s) Humans ; COVID-19 ; New Zealand/epidemiology ; Pandemics ; Retrospective Studies ; Liver Diseases/epidemiology ; Liver Diseases/etiology
    Language English
    Publishing date 2024-04-12
    Publishing country New Zealand
    Document type Letter
    ZDB-ID 390590-1
    ISSN 1175-8716 ; 0028-8446 ; 0110-7704
    ISSN (online) 1175-8716
    ISSN 0028-8446 ; 0110-7704
    DOI 10.26635/6965.6471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Biologic Augmentation of Isolated Meniscal Repair.

    Chen, Kevin / Aggarwal, Sarthak / Baker, Hayden / Athiviraham, Aravind

    Current reviews in musculoskeletal medicine

    2024  

    Abstract: Purpose of review: The limited blood supply and intrinsic healing capacity of the meniscus contributes to suboptimal tissue regeneration following injury and surgical repair. Biologic augmentation techniques have been utilized in combination with ... ...

    Abstract Purpose of review: The limited blood supply and intrinsic healing capacity of the meniscus contributes to suboptimal tissue regeneration following injury and surgical repair. Biologic augmentation techniques have been utilized in combination with isolated meniscal repair to improve tissue regeneration. Several innovative strategies such as Platelet-Rich Plasma (PRP), fibrin clots, mesenchymal stem cells (MSCs), bone marrow stimulation, meniscal scaffolds, and meniscal wrapping, are being explored to enhance repair outcomes. This article provides a comprehensive review of recent findings and conclusions regarding biologic augmentation techniques.
    Recent findings: Studies on PRP reveal mixed outcomes, with some suggesting benefits in reducing failure rates of isolated meniscal repair, while others question its efficacy. Fibrin clots and PRF (Platelet-rich fibrin), although promising, show inconsistent results and lack sufficient evidence for definitive conclusions. MSCs demonstrate potential in preclinical studies, but clinical trials have been limited and inconclusive. Bone marrow stimulation appears effective in certain contexts, but its broader applicability remains uncertain. Meniscal scaffolds, including CMI (Collagen Meniscal Implants) and Actifit (polyurethane scaffolds), show encouraging short- and mid-term outcomes but have not consistently surpassed traditional methods in the long term. Meniscal wrapping is infrequently studied but demonstrates positive short-term results with certain applications. The review reveals a diverse range of outcomes for biologic augmentation in meniscal repair. While certain techniques show promise, particularly in specific scenarios, the overall efficacy of these methods has yet to reach a consensus. The review underscores the necessity for standardized, high-quality research to establish the definitive effectiveness of these biologic augmentation methods.
    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2407827-X
    ISSN 1935-9748 ; 1935-973X
    ISSN (online) 1935-9748
    ISSN 1935-973X
    DOI 10.1007/s12178-024-09898-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Neuraxial Anesthesia and Analgesia During Cardiothoracic Surgery: A Narrative Review.

    Chen, Kevin / Gashler, Kyle / Li, Tommy / Nguyen, Anvinh

    Current pain and headache reports

    2024  

    Abstract: Purpose of review: The purpose of this review is to synthesize and examine the literature on the use of neuraxial anesthesia and analgesia during cardiothoracic surgery. As cardiothoracic procedures often require systemic anticoagulation, neuraxial ... ...

    Abstract Purpose of review: The purpose of this review is to synthesize and examine the literature on the use of neuraxial anesthesia and analgesia during cardiothoracic surgery. As cardiothoracic procedures often require systemic anticoagulation, neuraxial techniques are quite often underutilized due to the theoretical risk of epidural hematoma. In this review, we seek to examine the literature to review the indications and contraindications and to explore if neuraxial anesthesia and analgesia has a role in cardiothoracic surgery.
    Recent findings: Neuraxial techniques have multiple advantages during cardiothoracic surgery including coronary vasodilation, decreased sympathetic surge, and a decreased cortisol level leading to overall reduction in stress response. Multiple studies have shown an improvement in pain scores, reduction in pulmonary complications, faster extubation times, with minimal complications when neuraxial techniques are utilized in cardiothoracic surgeries. Given the numerous advantages and minimal complications of neuraxial techniques in cardiothoracic surgeries, we hope its utilization continues to increase. Moving forward, we hope additional studies continue to reaffirm the benefits of neuraxial anesthesia and analgesia for cardiothoracic surgeries to improve its utilization.
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2055062-5
    ISSN 1534-3081 ; 1531-3433
    ISSN (online) 1534-3081
    ISSN 1531-3433
    DOI 10.1007/s11916-024-01235-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Sino-Asia agricultural trade and development cooperation

    Rui, Mao / Chen, Kevin Z. / Chen, Kevin

    Progress, challenges, and outlook

    2023  

    Abstract: This book includes twelve chapters on agricultural trade and cooperation in Asia, which cover both the review of agricultural development in selected countries and analyses of their development linkages through trade and cooperation. Specific attention ... ...

    Abstract This book includes twelve chapters on agricultural trade and cooperation in Asia, which cover both the review of agricultural development in selected countries and analyses of their development linkages through trade and cooperation. Specific attention has been given to agricultural trade between China and the rest of developing Asia, as China has become the second largest country in agricultural trade, and the unique importance remains for trade partners in Asia due to geographic proximity. Following the outbreak of the COVID-19 pandemic, we also reveal how the global regime of agricultural trade and the Sino-Asia agricultural trade, in particular, has been affected. Overall, the book aims to enhance understanding of the progress, challenges, and outlooks of the Sino-Asia agricultural trade and highlight the room for further cross-country collaborations in agricultural development.

    PR

    IFPRI5; DCA; 3 Building Inclusive and Efficient Markets, Trade Systems, and Food Industry

    Development Strategies and Governance (DSG); Transformation Strategies

    340 pages
    Keywords agriculture ; agricultural trade ; cooperation ; economics ; Coronavirus ; coronavirus disease ; Coronavirinae ; COVID-19 ; Sino-Asia agricultural trade
    Subject code 381
    Language English
    Publisher Royal Collins Publishing Company
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Stem cell therapy for central nervous system disorders: Metabolic interactions between transplanted cells and local microenvironments.

    Sakowski, Stacey A / Chen, Kevin S

    Neurobiology of disease

    2022  Volume 173, Page(s) 105842

    Abstract: Stem cell therapy is a promising and rapidly advancing treatment strategy for a multitude of neurologic disorders. Yet, while early phase clinical trials are being pursued in many disorders, the mechanism of action often remains unclear. One important ... ...

    Abstract Stem cell therapy is a promising and rapidly advancing treatment strategy for a multitude of neurologic disorders. Yet, while early phase clinical trials are being pursued in many disorders, the mechanism of action often remains unclear. One important potential mechanism by which stem cells provide neuroprotection is through metabolic signaling with diseased neurons, glia, and other cell types in the nervous system microenvironment. Early studies exploring such interactions report normalization of glucose metabolism, induction of protective mitochondrial genes, and even interactions with supportive neurovasculature. Local metabolic conditions also impact stem cell biology, which can have a large impact on transplant viability and efficacy. Epigenetic changes that occur in the donor prior to collection of stem cells, and even during in vitro culture conditions, may have effects on stem cell biology that are carried into the host upon stem cell transplantation. Transplanted stem cells also face potentially toxic metabolic microenvironments at the targeted transplant site. Novel approaches for metabolically "preconditioning" stem cells prior to transplant harness metabolic machinery to optimize stem cell survival upon transplant. Ultimately, an improved understanding of the metabolic cross-talk between implanted stem cells and the local nervous system environment, in both disease and injury states, will increase the likelihood of success in translating stem cell therapy to early trials in neurological disease.
    MeSH term(s) Central Nervous System Diseases/therapy ; Glucose ; Humans ; Neurons/physiology ; Stem Cell Transplantation
    Chemical Substances Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-08-18
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1211786-9
    ISSN 1095-953X ; 0969-9961
    ISSN (online) 1095-953X
    ISSN 0969-9961
    DOI 10.1016/j.nbd.2022.105842
    Database MEDical Literature Analysis and Retrieval System OnLINE

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