LIVIVO - Search results -

Search results

Result 1 - 10 of total 101

Search options

Article ; Online: Prognostic Nutritional Index and the Risk of Postoperative Complications After Spine Surgery: A Meta-Analysis.

Guo, Hubing / Yang, Lingxia / Liu, Jin / Yu, Xinfu / Chen, Liqi / Huang, Yufeng

2024

Abstract: Background: A low prognostic nutritional index (PNI) may reflect malnutrition, which has been associated with poor prognosis in patients with various clinical conditions. The aim of the systematic review and meta-analysis was to investigate the ... ...

Abstract	Background: A low prognostic nutritional index (PNI) may reflect malnutrition, which has been associated with poor prognosis in patients with various clinical conditions. The aim of the systematic review and meta-analysis was to investigate the association between preoperative PNI and risk of postoperative complications in adult patients after spine surgery. Methods: An extensive search was conducted on PubMed, Embase, and Web of Science to identify relevant cohort studies. Random-effects models were employed to combine the findings, taking into account the potential influence of heterogeneity. Results: Ten cohort studies involving 3,249 patients receiving spine surgeries were included. Pooled results showed that a low preoperative prognostic nutritional index (PNI) was associated with an increased risk of overall postoperative complications in these patients (odds ratio [OR]: 1.82, 95% confidence interval [CI]: 1.42 to 2.34, P < 0.001; I Conclusions: A preoperative low prognostic nutritional index (PNI) may be a risk factor of increased incidence of overall postoperative complications, postoperative delirium, and surgical site infection in adult patients after spine surgeries.
Language	English
Publishing date	2024-02-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2024.02.077
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1159: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Characteristics associated with trial of labor among patients with twin pregnancies.

Cipres, Danielle T / Cowherd, Rachael / Barry, Olivia H / Chen, Liqi / Yee, Lynn M

American journal of perinatology

2024

Abstract: Objective: This study aimed to identify patient and provider factors associated with undergoing trial of labor among eligible patients with twin gestations.: Study design: This retrospective cohort study of patients with twin gestations who received ... ...

Abstract	Objective: This study aimed to identify patient and provider factors associated with undergoing trial of labor among eligible patients with twin gestations. Study design: This retrospective cohort study of patients with twin gestations who received care at a large tertiary care center from 2000-2016 included individuals with live pregnancies greater than twenty-three weeks of gestation and cephalic-presenting twin. Patients with a prior uterine scar or contraindication to vaginal delivery were excluded from analyses. Maternal and clinical characteristics were compared among patients who did and did not undergo trial of labor. Multivariable logistic regression models included characteristics chosen a priori and those with bivariable associations with p <0.1. Interactions between parity and other significant variables in the primary models were also investigated. Results: Among 1888 eligible patients, 80.7% (N=1524) underwent trial of labor. Those undergoing trial of labor were more likely to be younger, multiparous, and have a maternal-fetal medicine physician as the delivering provider (p<0.01). Hypertensive disorders of pregnancy were less prevalent among patients undergoing trial of labor (20.2% vs. 27.8%, p<0.01). In multivariable analysis, advanced maternal age (aOR 0.55, 95% CI 0.40-0.74) and nulliparity (aOR 0.36, 95% CI 0.25-0.52) conferred a lower odds of trial of labor, while having a maternal-fetal medicine provider (aOR 2.74, 95% CI 1.55-4.83) was associated with higher odds. Interaction analyses demonstrated no significant interaction effects between parity and other characteristics. Among those undergoing trial of labor, 76.0% (1158/1524) had a successful vaginal delivery of both twins, with 48.1% (557/1158) having breech extraction of the second twin. Conclusion: In this cohort of twin gestations with a high frequency of trial of labor, patient and provider characteristics are associated with attempting vaginal delivery. Variation in provider practices suggests differing skills and comfort with twin vaginal delivery may influence route of delivery decision-making in patients with twins.
Language	English
Publishing date	2024-03-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	605671-4
ISSN	1098-8785 ; 0735-1631
ISSN (online)	1098-8785
ISSN	0735-1631
DOI	10.1055/a-2295-3329
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1929: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: KLF5 promotes the ossification process of ligamentum flavum by transcriptionally activating CX43.

Guo, Hubing / Yang, Lingxia / Liu, Jin / Chen, Liqi / Huang, Yufeng / Li, Jinsong

Journal of orthopaedic surgery and research

2024 Volume 19, Issue 1, Page(s) 244

Abstract: Background: Ossification of ligamentum flavum (OLF) is a prevalent degenerative spinal disease, typically causing severe neurological dysfunction. Kruppel-like factor 5 (KLF5) plays an essential role in the regulation of skeletal development. However, ... ...

Abstract	Background: Ossification of ligamentum flavum (OLF) is a prevalent degenerative spinal disease, typically causing severe neurological dysfunction. Kruppel-like factor 5 (KLF5) plays an essential role in the regulation of skeletal development. However, the mechanism KLF5 plays in OLF remains unclear, necessitating further investigative studies. Methods: qRT-PCR, immunofluorescent staining and western blot were used to measure the expression of KLF5. Alkaline Phosphatase (ALP) staining, Alizarin red staining (ARS), and the expression of Runt-related transcription factor 2 (RUNX2), osteopontin (OPN), and osteocalcin (OCN) were used to evaluate the osteogenic differentiation. Luciferase activity assay and ChIP-PCR were performed to investigate the molecular mechanisms. Results: KLF5 was significantly upregulated in OLF fibroblasts in contrast to normal ligamentum flavum (LF) fibroblasts. Silencing KLF5 diminished osteogenic markers and mineralized nodules, while its overexpression had the opposite effect, confirming KLF5's role in promoting ossification. Moreover, KLF5 promotes the ossification of LF by activating the transcription of Connexin 43 (CX43), and overexpressing CX43 could reverse the suppressive impact of KLF5 knockdown on OLF fibroblasts' osteogenesis. Conclusion: KLF5 promotes the OLF by transcriptionally activating CX43. This finding contributes significantly to our understanding of OLF and may provide new therapeutic targets.
MeSH term(s)	Humans ; Cells, Cultured ; Connexin 43/genetics ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; Ligamentum Flavum ; Ossification, Heterotopic/genetics ; Ossification, Heterotopic/metabolism ; Osteogenesis/genetics ; Transcription Factors/metabolism
Chemical Substances	Connexin 43 ; KLF5 protein, human ; Kruppel-Like Transcription Factors ; Transcription Factors ; GJA1 protein, human
Language	English
Publishing date	2024-04-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2252548-8
ISSN	1749-799X ; 1749-799X
ISSN (online)	1749-799X
ISSN	1749-799X
DOI	10.1186/s13018-024-04702-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Risk Factors for the Development of Shoulder Pain in Elite Sled Hockey Players.

Spangenberg, Jacqueline / Nussbaum, Ryan / Chen, Liqi / Jayabalan, Prakash

PM & R : the journal of injury, function, and rehabilitation

2021 Volume 13, Issue 12, Page(s) 1392–1398

Abstract: Background: Shoulder pain is one of the most common injuries in adaptive athletes. There are minimal prior studies that investigate shoulder pain prevalence and associated risk factors in sled hockey players.: Objective: To characterize the ... ...

Abstract	Background: Shoulder pain is one of the most common injuries in adaptive athletes. There are minimal prior studies that investigate shoulder pain prevalence and associated risk factors in sled hockey players. Objective: To characterize the prevalence of shoulder pain in elite-level adaptive sled hockey athletes and identify associated risk factors. Design: Cross-sectional observational study. Setting: 2019 USA Sled Hockey Classic in Chicago, IL from 7 February 2019 to 10 February 2019. Participants: Eighty-two elite sled hockey athletes who participated in a nationally sanctioned sports event. Interventions: Not applicable. Main outcome measures: The primary outcome of the study was to describe the experience of shoulder pain using player-reported outcomes of pain including: binary (yes/no) pain reporting in the last month, Performance-Corrected Wheelchair User's Shoulder Pain Index (PC-WUSPI) reporting pain in the last week, and Visual Analog Scale (VAS) reporting pain in the last month. Associations were assessed between the measurements of pain and characteristics of participants. Results: Of all participants, 70.5% endorsed shoulder pain in the last month. The average VAS for the past month was 2.13 and average PC-WUSPI for the past week was 15.46. Statistically significant associations were found between endorsement of pain in the last month and specific correlative factors including increased weight (P value .008; odds ratio [OR] 1.04, 95% confidence interval [CI] 1.01-1.07) and increased duration of manual wheelchair use (P-value .002; OR 1.13, 95% CI 1.04-1.22). Conclusion: Elite-level sled hockey athletes commonly report experiencing shoulder pain. There is evidence that an elite-level sled hockey player's weight and longer duration of manual wheelchair use are both associated with a greater likelihood for self-reporting shoulder pain rather than number of years of playing the sport.
MeSH term(s)	Athletes ; Cross-Sectional Studies ; Hockey ; Humans ; Risk Factors ; Shoulder Pain/epidemiology ; Shoulder Pain/etiology
Language	English
Publishing date	2021-03-03
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	2608988-9
ISSN	1934-1563 ; 1934-1482
ISSN (online)	1934-1563
ISSN	1934-1482
DOI	10.1002/pmrj.12553
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6951: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Double Network Physical Crosslinked Hydrogel for Healing Skin Wounds: New Formulation Based on Polysaccharides and Zn

Cui, Shenghao / Yang, Faming / Yu, Dingyi / Shi, Chao / Zhao, Di / Chen, Liqi / Chen, Jingdi

International journal of molecular sciences

2023 Volume 24, Issue 17

Abstract: Developing convenient, efficient, and natural wound dressings remain the foremost strategy for treating skin wounds. Thus, we innovatively combined the semi-dissolved acidified sol-gel conversion method with the internal gelation method to fabricate SA ( ... ...

Abstract	Developing convenient, efficient, and natural wound dressings remain the foremost strategy for treating skin wounds. Thus, we innovatively combined the semi-dissolved acidified sol-gel conversion method with the internal gelation method to fabricate SA (sodium alginate)/CS (chitosan)/Zn
MeSH term(s)	Hydrogels/pharmacology ; Skin ; Polysaccharides/pharmacology ; Alginates ; Zinc
Chemical Substances	Hydrogels ; Polysaccharides ; Alginates ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2023-08-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms241713042
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Characteristics Associated with Trial of Labor among Patients with Twin Pregnancies

Cipres, Danielle T. / Cowherd, Rachael B. / Barry, Olivia H. / Chen, Liqi / Yee, Lynn M.

American Journal of Perinatology

2024

Abstract: Objective: This study aimed to identify patient and provider factors associated with undergoing trial of labor (TOL) among eligible patients with twin gestations.: Study Design: This retrospective cohort study of patients with twin gestations who ... ...

Abstract	Objective: This study aimed to identify patient and provider factors associated with undergoing trial of labor (TOL) among eligible patients with twin gestations. Study Design: This retrospective cohort study of patients with twin gestations who received care at a large tertiary care center from 2000 to 2016 included individuals with live pregnancies greater than 23 weeks of gestation and cephalic-presenting twin. Patients with a prior uterine scar or contraindication to vaginal delivery were excluded from analyses. Maternal and clinical characteristics were compared among patients who did and did not undergo TOL. Multivariable logistic regression models included characteristics chosen a priori and those with bivariable associations with p < 0.1. Interactions between parity and other significant variables in the primary models were also investigated. Results: Among 1,888 eligible patients, 80.7% ( N = 1,524) underwent TOL. Those undergoing TOL were more likely to be younger, multiparous, and have a maternal–fetal medicine physician as the delivering provider ( p < 0.01). Hypertensive disorders of pregnancy were less prevalent among patients undergoing TOL (20.2 vs. 27.8%, p < 0.01). In multivariable analysis, advanced maternal age (adjusted odds ratio [aOR]: 0.55, 95% confidence interval [CI]: 0.40–0.74) and nulliparity (aOR: 0.36, 95% CI: 0.25–0.52) conferred a lower odds of TOL, while having a maternal–fetal medicine provider (aOR: 2.74, 95% CI: 1.55–4.83) was associated with higher odds. Interaction analyses demonstrated no significant interaction effects between parity and other characteristics. Among those undergoing a TOL, 76.0% (1,158/1,524) had a successful vaginal delivery of both twins, with 48.1% (557/1,158) having breech extraction of the second twin. Conclusion: In this cohort of twin gestations with a high frequency of TOL, patient and provider characteristics are associated with attempting vaginal delivery. Variation in provider practices suggests differing skills and comfort with twin vaginal delivery may influence route of delivery decision-making in patients with twins. Keypoints: Most patients with twin pregnancies undergoing TOL had successful vaginal deliveries. Having an MFM delivering provider was associated with higher odds of attempting twin TOL. Nulliparity and advanced maternal age were associated with lower odds of twin TOL.
Keywords	breech extraction ; delivery route ; maternal–fetal medicine ; trial of labor ; twin pregnancy ; vaginal delivery
Language	English
Publishing date	2024-03-26
Publisher	Thieme Medical Publishers, Inc.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	605671-4
ISSN	1098-8785 ; 0735-1631
ISSN (online)	1098-8785
ISSN	0735-1631
DOI	10.1055/a-2295-3329
Database	Thieme publisher's database

In stock of ZB MED Cologne/Königswinter

Zs.A 1929: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Marine-Derived Bioactive Peptides Self-Assembled Multifunctional Materials: Antioxidant and Wound Healing

Yu, Dingyi / Cui, Shenghao / Chen, Liqi / Zheng, Shuang / Zhao, Di / Yin, Xinyu / Yang, Faming / Chen, Jingdi

Antioxidants. 2023 May 31, v. 12, no. 6

2023

Abstract: Peptide self-assembling materials have received significant attention from researchers in recent years, emerging as a popular field in biological, environmental, medical, and other new materials studies. In this study, we utilized controllable enzymatic ... ...

Abstract	Peptide self-assembling materials have received significant attention from researchers in recent years, emerging as a popular field in biological, environmental, medical, and other new materials studies. In this study, we utilized controllable enzymatic hydrolysis technology (animal proteases) to obtain supramolecular peptide self-assembling materials (CAPs) from the Pacific oyster (Crassostrea gigas). We conducted physicochemical analyses to explore the pro-healing mechanisms of CAPs on skin wounds in both in vitro and in vivo experiments through a topical application. The results demonstrated that CAPs exhibit a pH-responsive behavior for self-assembly and consist of peptides ranging from 550 to 2300 Da in molecular weight, with peptide chain lengths of mainly 11–16 amino acids. In vitro experiments indicated that CAPs display a procoagulant effect, free radical scavenging activity, and promote the proliferation of HaCaTs (112.74% and 127.61%). Moreover, our in vivo experiments demonstrated that CAPs possess the ability to mitigate inflammation, boost fibroblast proliferation, and promote revascularization, which accelerates the epithelialization process. Consequently, a balanced collagen I/III ratio in the repaired tissue and the promotion of hair follicle regeneration were observed. With these remarkable findings, CAPs can be regarded as a natural and secure treatment option with high efficacy for skin wound healing. The potential of CAPs to be further developed for traceless skin wound healing is an exciting area for future research and development.
Keywords	Crassostrea gigas ; animals ; antioxidants ; collagen ; enzymatic hydrolysis ; fibroblasts ; free radicals ; hair follicles ; inflammation ; molecular weight ; peptides ; proteinases ; research and development ; topical application
Language	English
Dates of publication	2023-0531
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2704216-9
ISSN	2076-3921
ISSN	2076-3921
DOI	10.3390/antiox12061190
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: The demographic and disability characteristics of individuals who regularly attend an urban adaptive fitness center: An observational study.

Nalla, Sindhoori / Huang, Kevin / Spangenberg, Jacqueline / Chen, Liqi / Jayabalan, Prakash

PM & R : the journal of injury, function, and rehabilitation

2021 Volume 14, Issue 12, Page(s) 1454–1460

Abstract: Introduction: While it is well known that regular physical activity provides significant physical and psychosocial health benefits, people with disabilities have disproportionately lower rates of exercise compared to the able-bodied population. Reduced ... ...

Abstract	Introduction: While it is well known that regular physical activity provides significant physical and psychosocial health benefits, people with disabilities have disproportionately lower rates of exercise compared to the able-bodied population. Reduced levels of physical activity can put this population at an increased risk of chronic health conditions, highlighting the importance of ensuring that our communities have accessible adaptive fitness opportunities. Objectives: To evaluate the demographic and disability characteristics in individuals who regularly attend a specialized urban adaptive fitness center, to provide foundational understanding about the population that uses such resources. Design: Cross-sectional study SETTING: Specialized urban adaptive fitness center PARTICIPANTS: Sixty-three (n = 63) participants who regularly attend an urban Adaptive Sports and Fitness Center INTERVENTION: Not applicable MAIN OUTCOME MEASURE: World Health Organization (WHO) Disability Assessment Schedule (WHODAS) 2.0, evaluating disability in six domains: cognition, mobility, self-care, getting along, life activities, and participation. Results were converted into scores ranging from 0 (no disability) to 100 (total disability) and compared to WHO published norms for the general population and a demographics intake form. Results: Participants with mean age of 52.9 ±14.3 years were grouped into three diagnostic categories: spinal cord injury (30.2%), traumatic brain injury/stroke (36.5%), and other neurologic disease/chronic medical disease (33.3%). A total of 45.9% live alone, 96.8% exercise at least twice/week, and 43.5% participate in adaptive sports. Participants travel 8.0 miles on average for attendance. WHODAS disability summary score was 26.48 (86th percentile). Conclusions: Although adaptive fitness center participants had a higher level of disability than 80% to 90% of the general population, regular participation was realistic and feasible. Further understanding of the barriers in those who do not engage in such facilities is needed.
MeSH term(s)	Humans ; Adult ; Middle Aged ; Aged ; Cross-Sectional Studies ; Fitness Centers ; Disabled Persons/psychology ; Disability Evaluation ; World Health Organization
Language	English
Publishing date	2021-11-18
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	2608988-9
ISSN	1934-1563 ; 1934-1482
ISSN (online)	1934-1563
ISSN	1934-1482
DOI	10.1002/pmrj.12720
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6951: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Distributions of water-soluble ions in size-aggregated aerosols over the Southern Ocean and coastal Antarctica.

Xu, Guojie / Chen, Liqi / Xu, Tianyi / He, Shichang / Gao, Yuan

Environmental science. Processes & impacts

2021 Volume 23, Issue 9, Page(s) 1316–1327

Abstract: To investigate mass size distributions of water-soluble ions in aerosols in the marine boundary layer (MBL) over the Southern Ocean, size-segregated (0.056-18 μm in aerodynamic diameter) aerosols were collected on the ... ...

Abstract	To investigate mass size distributions of water-soluble ions in aerosols in the marine boundary layer (MBL) over the Southern Ocean, size-segregated (0.056-18 μm in aerodynamic diameter) aerosols were collected on the 28
MeSH term(s)	Aerosols/analysis ; Air Pollutants/analysis ; Antarctic Regions ; Ecosystem ; Environmental Monitoring ; Ions/analysis ; Oceans and Seas ; Water
Chemical Substances	Aerosols ; Air Pollutants ; Ions ; Water (059QF0KO0R)
Language	English
Publishing date	2021-09-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2703814-2
ISSN	2050-7895 ; 2050-7887
ISSN (online)	2050-7895
ISSN	2050-7887
DOI	10.1039/d1em00089f
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 7401: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Relationship of anthropometric measurements and percent body fat mass to cardiovascular disease risk factors in adults with cerebral palsy.

Kivlehan, Emily / Gaebler-Spira, Deborah / Chen, Liqi / Garrett, Ariane / Wysocki, Nicole / Marciniak, Christina

PM & R : the journal of injury, function, and rehabilitation

2022 Volume 15, Issue 2, Page(s) 192–202

Abstract: Introduction: Adults with cerebral palsy (CP) face high morbidity from cardiovascular disease (CVD). Of concern, classic screening parameters are inconsistent in identifying CVD risk in this population. Dual-energy x-ray absorptiometry (DEXA), which ... ...

Abstract	Introduction: Adults with cerebral palsy (CP) face high morbidity from cardiovascular disease (CVD). Of concern, classic screening parameters are inconsistent in identifying CVD risk in this population. Dual-energy x-ray absorptiometry (DEXA), which provides direct measurements of fat mass (FM), may be an alternative screening method. Objective: To evaluate whether FM measurement with DEXA is feasible in screening adults with CP and compare FM and anthropometric measures to CVD risk factors. Design: Cross-sectional study. Setting: Outpatient rehabilitation hospital. Participants: Forty-seven adults with CP. Main outcome measures: Weight, height, waist circumference (WC), and hip circumference (HC) were measured; waist-to-hip ratio (WHR) and body mass index (BMI) were calculated. Blood pressure (BP), FM by DEXA, hemoglobin A1c (HbA1c), and lipid measurements were obtained. Logistic regression models investigated odds ratios (ORs) and 95% confidence intervals (CIs) between anthropometric measurements/FM and CVD risk factors; correlations were assessed using Pearson correlation coefficients. Results: Elevated BP or hypertension diagnosis was present in 47.8%; HbA1c ≥5.7% in 22.2%; and high-density lipoprotein (HDL) level below optimal for 33.3%. DEXA FM was obtained in 29 of 47 participants, as surgical metal and positioning limited many studies. Excess FM was noted in 75.9% versus 41.3% overweight/obese by BMI. WC correlated with HbA1c (r = 0.46, p = .002), HDL (r = -0.36, p = .018), and triglyceride (TG) levels (r = 0.30, p = .045); however at-risk WC values were associated only with odds of elevated HbA1c (OR 8.53, 95% CI 1.46-50.05; p = .018). HC correlated with HbA1c levels (r = 0.38, p = .011) and systolic BPs (r = 0.35, p = .019); similarly, ORs for elevated HC were weakly associated with elevated HbA1c and BPs (OR 1.08, 95% CI 1.01-1.16; p = .024 and OR 1.07, 95% CI 1.01-1.14; p = .024, respectively). WHR correlated with TGs; however few TG levels were elevated. FM measures were not associated with at-risk lab values or BPs. Conclusions: DEXA FM measurements may not be feasible for CVD screening in many adults with CP. Although CVD risk factors are frequently present, anthropometric measurements commonly used for general population screening may not translate well to adults with CP.
MeSH term(s)	Humans ; Adult ; Cardiovascular Diseases/epidemiology ; Risk Factors ; Glycated Hemoglobin ; Cerebral Palsy/complications ; Cross-Sectional Studies ; Body Mass Index ; Adipose Tissue
Chemical Substances	Glycated Hemoglobin
Language	English
Publishing date	2022-07-04
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2608988-9
ISSN	1934-1563 ; 1934-1482
ISSN (online)	1934-1563
ISSN	1934-1482
DOI	10.1002/pmrj.12797
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6951: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito