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Article ; Online: Leveraging Molecular Assays to Aid Decision-making in Large Indeterminate Thyroid Nodules-A Minimalist Approach.

Chen, Michelle M / Ho, Allen S

JAMA otolaryngology-- head & neck surgery

2022 Volume 148, Issue 4, Page(s) 383

MeSH term(s)	Biopsy, Fine-Needle ; Humans ; Retrospective Studies ; Thyroid Neoplasms/surgery ; Thyroid Nodule/surgery
Language	English
Publishing date	2022-02-17
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2701825-8
ISSN	2168-619X ; 2168-6181
ISSN (online)	2168-619X
ISSN	2168-6181
DOI	10.1001/jamaoto.2021.4433
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Article ; Online: Diagnostic Assessment (Imaging) and Staging of Laryngeal Cancer.

Itamura, Kyohei / Hsue, Victor B / Barbu, Anca M / Chen, Michelle M

Otolaryngologic clinics of North America

2023 Volume 56, Issue 2, Page(s) 215–231

Abstract: Diagnosis of larynx cancer relies on a detailed history and physical and objective assessment with endoscopy and imaging. Endoscopy is needed to assess for vocal fold function that directly affects staging. Computed tomography and MRI can be used to ... ...

Abstract	Diagnosis of larynx cancer relies on a detailed history and physical and objective assessment with endoscopy and imaging. Endoscopy is needed to assess for vocal fold function that directly affects staging. Computed tomography and MRI can be used to assess for tumor extent in relation to intra- and extra-laryngeal structures, especially paraglottic and pre-epiglottic space involvement as well as cartilage invasion. Accurate staging is critical for subsequent treatment decision-making regarding larynx preservation.
MeSH term(s)	Humans ; Laryngeal Neoplasms/diagnostic imaging ; Laryngeal Neoplasms/pathology ; Neoplasm Staging ; Larynx/diagnostic imaging ; Larynx/pathology ; Tomography, X-Ray Computed ; Vocal Cords/pathology
Language	English
Publishing date	2023-02-13
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	417489-6
ISSN	1557-8259 ; 0030-6665
ISSN (online)	1557-8259
ISSN	0030-6665
DOI	10.1016/j.otc.2022.12.006
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Article ; Online: Sinonasal Tumors Masquerading as Invasive Fungal Sinusitis (IFS).

Pak, Kaitlynne Y / Hsue, Victor B / Lee, Matthew K / Chen, Michelle M / Balzer, Bonnie / Wu, Arthur W / Tang, Dennis M

The Annals of otology, rhinology, and laryngology

2024 Volume 133, Issue 6, Page(s) 625–627

Abstract: Objectives: Fungal tissue invasion in the setting of sinonasal malignancy has been rarely described in the literature. Only a handful of studies have discussed cases of suspected chronic and acute IFS (CIFS and AIFS, respectively), having an underlying ... ...

Abstract	Objectives: Fungal tissue invasion in the setting of sinonasal malignancy has been rarely described in the literature. Only a handful of studies have discussed cases of suspected chronic and acute IFS (CIFS and AIFS, respectively), having an underlying undifferentiated sinonasal carcinoma, sinonasal teratocarcinosarcoma, and NK/T-cell lymphoma. Methods: Here, we describe 3 cases of carcinoma mimicking IFS from a single institution. Results: Each of our patients presented with sinonasal complaints as an outpatient in the setting of immunosuppression. Intranasal biopsies consistently were predominated by necrotic debris, with and without fungal elements, ultimately leading to a delay of oncologic care. The final pathologies included NK/T-cell lymphoma and SNEC. All patients were followed by radiation and chemotherapy, with 1 case of mortality. Conclusions: We aim to emphasize the importance of obtaining viable tissue as pathology specimens as the presence of necrosis with fungal elements may limit the diagnosis and ultimately delay the care of an underlying sinonasal carcinoma.
MeSH term(s)	Humans ; Diagnosis, Differential ; Sinusitis/diagnosis ; Sinusitis/microbiology ; Male ; Middle Aged ; Paranasal Sinus Neoplasms/diagnosis ; Paranasal Sinus Neoplasms/pathology ; Female ; Aged ; Invasive Fungal Infections/diagnosis ; Carcinoma/diagnosis ; Carcinoma/pathology ; Biopsy ; Tomography, X-Ray Computed ; Maxillary Sinus Neoplasms
Language	English
Publishing date	2024-03-16
Publishing country	United States
Document type	Journal Article ; Case Reports
ZDB-ID	120642-4
ISSN	1943-572X ; 0003-4894
ISSN (online)	1943-572X
ISSN	0003-4894
DOI	10.1177/00034894241238864
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Article ; Online: Complications of Transoral Robotic Surgery.

Sethi, Rosh K V / Chen, Michelle M / Malloy, Kelly M

Otolaryngologic clinics of North America

2020 Volume 53, Issue 6, Page(s) 1109–1115

Abstract: This article summarizes major and minor complications following transoral robotic surgery in the head and neck. Overall, transoral robotic surgery is extremely safe; however, surgeons must recognize inherent risks associated with major and severe ... ...

Abstract	This article summarizes major and minor complications following transoral robotic surgery in the head and neck. Overall, transoral robotic surgery is extremely safe; however, surgeons must recognize inherent risks associated with major and severe bleeding, dysphagia, and minor complications, including injury to nerves, mucosal surfaces, teeth, and the eyes. This article briefly discusses prevention and management strategies for common complications.
MeSH term(s)	Female ; Head/surgery ; Humans ; Natural Orifice Endoscopic Surgery/adverse effects ; Natural Orifice Endoscopic Surgery/methods ; Neck/surgery ; Postoperative Complications/etiology ; Postoperative Complications/prevention & control ; Postoperative Complications/therapy ; Robotic Surgical Procedures/adverse effects ; Robotic Surgical Procedures/methods
Language	English
Publishing date	2020-09-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	417489-6
ISSN	1557-8259 ; 0030-6665
ISSN (online)	1557-8259
ISSN	0030-6665
DOI	10.1016/j.otc.2020.07.017
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Article ; Online: Peace of Mind: A Role in Unnecessary Care?

Chen, Michelle M / Hughes, Tasha M / Dossett, Lesly A / Pitt, Susan C

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

2021 Volume 40, Issue 5, Page(s) 433–437

MeSH term(s)	Adaptation, Psychological ; Attitude of Health Personnel ; Clinical Decision-Making ; Decision Making, Shared ; Emotions ; Health Behavior ; Health Knowledge, Attitudes, Practice ; Humans ; Patient Participation ; Patient Safety ; Patient-Centered Care ; Quality of Life ; Risk Assessment ; Unnecessary Procedures/psychology
Language	English
Publishing date	2021-12-09
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	604914-x
ISSN	1527-7755 ; 0732-183X
ISSN (online)	1527-7755
ISSN	0732-183X
DOI	10.1200/JCO.21.01895
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Zs.A 1847: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Minimally Invasive Surgery in the United States, 2022: Understanding Its Value Using New Datasets.

Mattingly, Aviva S / Chen, Michelle M / Divi, Vasu / Holsinger, F Christopher / Saraswathula, Anirudh

The Journal of surgical research

2022 Volume 281, Page(s) 33–36

Abstract: Introduction: While minimally invasive surgery (MIS) has transformed the treatment landscape of surgical care, its utilization is not well understood. The newly released Nationwide Ambulatory Surgery Sample allows for more accurate estimates of MIS ... ...

Abstract	Introduction: While minimally invasive surgery (MIS) has transformed the treatment landscape of surgical care, its utilization is not well understood. The newly released Nationwide Ambulatory Surgery Sample allows for more accurate estimates of MIS volume in the United States-in combination with inpatient datasets. Materials and methods: Multiple nationwide databases from the Healthcare Cost and Utilization Project (HCUP) were used: the Nationwide Ambulatory Surgery Sample and National Inpatient Sample. The volume of MIS and robotic procedures were calculated from 2016 to 2018. An online query system, HCUPNet, was queried for inpatient stays from 1993 to 2014. Results: In 2017, 9.8 million inpatient major operating room procedures were analyzed, of which 11.1% were MIS and 2.5% were robotic-assisted, compared with 9.6 million inpatient operating room procedures (11.2% MIS and 2.9% robotic-assisted) in 2018. There were 10.6, 10.6, and 10.7 million ambulatory procedures in 2016, 2017, and 2018, respectively. Ambulatory MIS procedures showed an increasing trend across years, representing 16.9%, 17.4%, and 18%, respectively. HCUPNet data revealed an increase in inpatient MIS cases from 529,811 (8.9%) in 1993 to 1,443,446 (20.7%) in 2014. Conclusions: This study is the first to estimate national MIS volume across specialties in both inpatient and ambulatory hospital settings. We found a trend toward a higher proportion of MIS and robotic cases from 1997 to 2018. These data may help contribute to a more comprehensive understanding of MIS value within surgery and highlight limitations of current databases, especially when categorizing robotic cases on a national scale.
MeSH term(s)	United States ; Humans ; Minimally Invasive Surgical Procedures/methods ; Robotics ; Ambulatory Surgical Procedures ; Databases, Factual ; Inpatients ; Retrospective Studies ; Robotic Surgical Procedures
Language	English
Publishing date	2022-09-14
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80170-7
ISSN	1095-8673 ; 0022-4804
ISSN (online)	1095-8673
ISSN	0022-4804
DOI	10.1016/j.jss.2022.08.006
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Zs.A 178: Show issues

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Article ; Online: Impact of monoclonal antibody therapy for head and neck cancer on end-of-life care utilization and costs.

Benjamin, William J / Yalamanchi, Pratyusha / Taylor, Jeremy M G / Lenze, Nicholas / Worden, Francis P / Chinn, Steven B / Chen, Michelle M

Head & neck

2023 Volume 45, Issue 6, Page(s) 1468–1475

Abstract: Background: The impact of monoclonal antibody therapy (mAB) for advanced head and neck cancer on end-of-life health care utilization and costs has yet to be adequately studied.: Methods: Retrospective cohort study of patients aged 65 and over with a ... ...

Abstract	Background: The impact of monoclonal antibody therapy (mAB) for advanced head and neck cancer on end-of-life health care utilization and costs has yet to be adequately studied. Methods: Retrospective cohort study of patients aged 65 and over with a diagnosis of head and neck cancer between 2007 and 2017 within the SEER-Medicare registry assessing the impact of mAB therapy (i.e., cetuximab, nivolumab, or pembrolizumab) on end-of-life health care utilization (ED visits, inpatient admissions, ICU admissions, and hospice claims) and costs. Results: Of 12 544 patients with HNC, 270 (2.2%) utilized mAB therapy at the end-of-life period. On multivariable analyses adjusting for demographic and clinicopathologic characteristics, there was a significant association between mAB therapy and emergency department visits (OR: 1.38, 95% CI: 1.1-1.8, p = 0.01) and healthcare costs (β: $9760, 95% CI: 5062-14 458, p < 0.01). Conclusions: mAB use is associated with higher emergency department utilization and health care costs potentially due to infusion-related and drug toxicity expenses.
MeSH term(s)	Humans ; Aged ; United States ; Medicare ; Retrospective Studies ; Terminal Care ; Health Care Costs ; Head and Neck Neoplasms/drug therapy ; Nivolumab ; Death
Chemical Substances	Nivolumab (31YO63LBSN)
Language	English
Publishing date	2023-03-28
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	645165-2
ISSN	1097-0347 ; 0148-6403 ; 1043-3074
ISSN (online)	1097-0347
ISSN	0148-6403 ; 1043-3074
DOI	10.1002/hed.27359
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Zs.A 1493: Show issues

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Article ; Online: End-of-Life Costs and Hospice Utilization in Patients with Head and Neck Cancer.

Chen, Michelle M / Rosenthal, Eben L / Divi, Vasu

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

2019 Volume 161, Issue 3, Page(s) 439–441

Abstract: The Quality Oncology Practice Initiative has several metrics related to end-of life (EOL) care, including hospice enrollment ≤3 days, with lower scores signaling better performance. Of privately insured patients with head and neck cancer, 3.5% were ... ...

Abstract	The Quality Oncology Practice Initiative has several metrics related to end-of life (EOL) care, including hospice enrollment ≤3 days, with lower scores signaling better performance. Of privately insured patients with head and neck cancer, 3.5% were enrolled in hospice prior to death and 21.3% spent ≤3 days in hospice, indicating aggressive EOL care. Patients with late hospice enrollment had higher spending in the last 30 days of life (DOL). Patients in hospice ≤3 days spent $37,426, while those in hospice >3 days spent $24,418 (
MeSH term(s)	Facilities and Services Utilization/statistics & numerical data ; Female ; Head and Neck Neoplasms/therapy ; Hospice Care/economics ; Hospice Care/statistics & numerical data ; Humans ; Male ; Middle Aged ; Terminal Care/economics ; Time Factors
Language	English
Publishing date	2019-04-23
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	392085-9
ISSN	1097-6817 ; 0161-6439 ; 0194-5998
ISSN (online)	1097-6817
ISSN	0161-6439 ; 0194-5998
DOI	10.1177/0194599819846072
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Article ; Online: Morbidity and Mortality Associated With Robotic Head and Neck Surgery: An Inquiry of the Food and Drug Administration Manufacturer and User Facility Device Experience Database.

Chen, Michelle M / Holsinger, F Christopher

JAMA otolaryngology-- head & neck surgery

2016 Volume 142, Issue 4, Page(s) 405–406

MeSH term(s)	Head and Neck Neoplasms/surgery ; Humans ; Morbidity/trends ; Natural Orifice Endoscopic Surgery ; Postoperative Complications/epidemiology ; Robotics/legislation & jurisprudence ; Robotics/methods ; Survival Rate/trends ; United States/epidemiology ; United States Food and Drug Administration/legislation & jurisprudence
Language	English
Publishing date	2016-04
Publishing country	United States
Document type	Letter
ZDB-ID	2701825-8
ISSN	2168-619X ; 2168-6181
ISSN (online)	2168-619X
ISSN	2168-6181
DOI	10.1001/jamaoto.2015.3673
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Article: Diagnosis and Management of Congenital Sensorineural Hearing Loss.

Chen, Michelle M / Oghalai, John S

Current treatment options in pediatrics

2016 Volume 2, Issue 3, Page(s) 256–265

Abstract: Hearing loss is the most common sensory disorder in the USA. The diagnosis of congenital hearing loss starts with newborn hearing screening, which is best performed with auditory brainstem evoked responses in order to avoid the risk of missing auditory ... ...

Abstract	Hearing loss is the most common sensory disorder in the USA. The diagnosis of congenital hearing loss starts with newborn hearing screening, which is best performed with auditory brainstem evoked responses in order to avoid the risk of missing auditory neuropathy spectrum disorder. A careful history and physical exam can occasionally help reveal the etiology for congenital hearing loss. Imaging studies, either CT temporal bones or MRI of the internal auditory canals without gadolinium, and genetic testing, in particular for connexin 26, connexin 30, and Pendred syndrome, are the most useful diagnostic tests. Management of congenital hearing loss involves early fitting of amplification. Early cochlear implantation, preferably before 2 years of age, should be strongly considered for children with bilateral severe hearing loss.
Language	English
Publishing date	2016-07-08
Publishing country	Switzerland
Document type	Journal Article
ISSN	2198-6088
ISSN	2198-6088
DOI	10.1007/s40746-016-0056-6
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