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  1. Article ; Online: Challenges for hepatitis B control in Asia-Pacific areas: Consolidating vaccination and rolling-out antiviral therapies.

    Chen, Pei-Jer

    Journal of gastroenterology and hepatology

    2024  

    Abstract: Chronic hepatitis B (CHB) was, and still is, a prevalent liver disease in the world, especially high in the Asia-Pacific areas. With the advent of preventive vaccines and effective viral suppression drugs and active implementations, CHB has gradually ... ...

    Abstract Chronic hepatitis B (CHB) was, and still is, a prevalent liver disease in the world, especially high in the Asia-Pacific areas. With the advent of preventive vaccines and effective viral suppression drugs and active implementations, CHB has gradually become under control. The world-wide prevalence reduces from 4.2% in 1980 to 3.2% in 2020 study. CHB patients receiving long-term antiviral therapies significantly improve the clinical outcomes, saving from end-stage liver diseases. Despite of these impressive progresses, to meet the WHO sustained development goals (SDG) for CHB control, a 90% reduction of incidence and a 65% reduction of mortality in year 2030, there is still a long way to go. In this review, four ongoing approaches have been proposed: (i) A continuous monitoring of long-term vaccine efficacy in vaccinated populations; (ii) consolidating the hepatitis B virus vaccination program against vaccine hesitancy and limited resources; (iii) rolling-out current oral antivirals to more CHB patients not only for diseases treatment but also for infection preventions; and (iv) development of curative therapies, both friendly-to-dispense and affordable. A coherent and persevere efforts by the society may succeed and achieve the SDG for CHB in the future.
    Language English
    Publishing date 2024-02-27
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 632882-9
    ISSN 1440-1746 ; 0815-9319
    ISSN (online) 1440-1746
    ISSN 0815-9319
    DOI 10.1111/jgh.16528
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  2. Article ; Online: Queer feminist assemblages against far-right anti- "Anti-Discrimination Law" in South Korea.

    Chen, Pei Jean

    Journal of lesbian studies

    2023  , Page(s) 1–7

    Abstract: Anti-feminist, anti-Queer politics, and Christianity have long been allies in South Korea fervently against any progressive movement involving women and sexual minorities. Since the 2010s, the societal context has shifted to include the long recession ... ...

    Abstract Anti-feminist, anti-Queer politics, and Christianity have long been allies in South Korea fervently against any progressive movement involving women and sexual minorities. Since the 2010s, the societal context has shifted to include the long recession and neoliberal structural reforms after the 1997 Asian Financial Crisis. As a result, far-right religious groups never cease attempts to divide society based on gender, sexuality, and the Anti-Discrimination Law" To prevent "sexual orientation" from being protected under the Anti-Discrimination Act, these groups accused sexual minorities and members of advocacy groups of being pro-North Korea and pro-communist. The anti- LGBTQ groups furthered their discourse in the name of "protecting national security;" simultaneously, sexual minorities and family members of the shipwreck victims, migrant workers, and even disabled persons were treated as "non-nationals" and "pro-North Korea." Against this backdrop, Queer feminist assemblage provides creative ways to articulate the controversies, with the alliance and lived experiences of minorities.
    Language English
    Publishing date 2023-07-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2221436-7
    ISSN 1540-3548 ; 1089-4160
    ISSN (online) 1540-3548
    ISSN 1089-4160
    DOI 10.1080/10894160.2023.2240551
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  3. Article ; Online: Evolution trend and mechanism of the rebound effect of agricultural chemical fertilizer

    CHEN Pei, CAI Rong

    Ziyuan Kexue, Vol 45, Iss 4, Pp 750-

    An empirical analysis of Shaanxi Province

    2023  Volume 761

    Abstract: Objective] Under the background of accelerating the development of green agricultural transformation, clarifying the impact and mechanism of agricultural technological progress on the “rebound effect” of chemical fertilizer is of great significance for ... ...

    Abstract [Objective] Under the background of accelerating the development of green agricultural transformation, clarifying the impact and mechanism of agricultural technological progress on the “rebound effect” of chemical fertilizer is of great significance for the formulation of fertilizer saving policies and green and sustainable development. [Methods] Based on the county data of Shaanxi Province from 2000 to 2019, the semi-parameter spatial lag model was used to measure the rebound effect of agricultural chemical fertilizer, and the trend of the rebound effect and the deep-level reasons behind the occurrence of the “tempering effect” or “excessive storage effect” were analyzed. On this basis, the fixed effect model was used to examine the mechanism of agricultural technology progress affecting the rebound effect of chemical fertilizer. [Results] The results show that: (1) The mean value of the rebound effect of chemical fertilizer in the sample areas was 0.250, showing a “partial rebound”, indicating that although agricultural technological progress reduced fertilizer, 25% of the fertilizer reduction was offset by a new round of fertilizer consumption demand brought about by technological progress. (2) The rebound effect of agricultural chemical fertilizer in the sample area fluctuated greatly in different years, and in some years chemical fertilizer use showed “excessive storage effect” or “backfire effect”. In general, the rebound effect of chemical fertilizer showed a downward trend. (3) The mechanism analysis showed that agricultural technology progress caused the rebound effect of agricultural chemical fertilizer through three mechanisms the improvement of fertilizer use efficiency, the expansion of farmland management scale, and the “non-grain” trend of planting structure change. [Conclusion] Greening of agricultural development should be strengthened, incorrect conception of fertilization should be changed, and multi-pronged policy measures should be taken to reduce the rebound effect of chemical fertilizer; ...
    Keywords |agricultural technology progress|rebound effect of agricultural chemical fertilizer|semi-parametric spatial lag model|fertilizer use efficiency|scale of agricultural land operation|planting structure|shaanxi province ; Environmental sciences ; GE1-350 ; Biology (General) ; QH301-705.5
    Subject code 630
    Language Chinese
    Publishing date 2023-04-01T00:00:00Z
    Publisher Science Press, PR China
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Reablement of Instrumental Activities of Daily Living for Patients With Stroke: A Randomized Crossover Trial.

    Chen, Pei-Tsen / Chiu, En-Chi

    The American journal of occupational therapy : official publication of the American Occupational Therapy Association

    2024  Volume 78, Issue 2

    Abstract: Importance: Reablement is a person-centered and goal-oriented rehabilitative intervention to optimize people's chances to live independently.: Objective: To investigate the effects of a reablement intervention on performance of instrumental ... ...

    Abstract Importance: Reablement is a person-centered and goal-oriented rehabilitative intervention to optimize people's chances to live independently.
    Objective: To investigate the effects of a reablement intervention on performance of instrumental activities of daily living (IADLs) in three aspects (i.e., actual performance, ability, and self-perceived difficulty) for patients with stroke.
    Design: A single-blinded, randomized crossover study.
    Setting: Participants' home and community.
    Participants: Twenty-seven patients with stroke.
    Interventions: Each participant received two interventions (IADL reablement and health education). Each intervention was administered for 6 wk. All participants were randomly assigned to one intervention and then received the other intervention after a 4-wk washout period.
    Outcomes and measures: Outcomes of actual performance and self-perceived difficulty were derived from the Frenchay Activities Index (FAI) and the difficulty dimension of the Participation Measure-3 Domains, 4 Dimensions (PM-3D4D), respectively. Outcomes of ability were measured with the Lawton Instrumental Activities of Daily Living Scale (LIADL) and the Canadian Occupational Performance Measure Performance score (COPM Performance).
    Results: No statistically significant differences were found in the three aspects between the IADL reablement and health education (ps = .148-.570). Compared with the health education, the IADL reablement showed better improvements on the FAI, LIADL, COPM Performance, and difficulty dimension of the PM-3D4D with trivial to small effect sizes (ds = 0.17-0.45).
    Conclusions and relevance: Our results reveal that the IADL reablement has the potential to increase the frequency of IADL administration, enhancing the capability to perform IADLs and reducing the self-perceived difficulty of carrying out IADLs. Plain-Language Summary: The results of this study showed positive outcomes for a reablement intervention that focuses on goal-oriented instrumental activities of daily living for patients with stroke. An IADL reablement intervention may be useful for improving the ability to carry out IADL tasks at home and in the community.
    MeSH term(s) Humans ; Activities of Daily Living ; Cross-Over Studies ; Canada ; Stroke
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 219403-x
    ISSN 1943-7676 ; 0272-9490 ; 0161-326X
    ISSN (online) 1943-7676
    ISSN 0272-9490 ; 0161-326X
    DOI 10.5014/ajot.2024.050288
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  5. Article: [Applying Problem Behavior Theory to Investigate the Factors Affecting Tobacco Products Use by Students at Eight Universities in the Greater Taipei Area].

    Zheng, Yun-Xuan / Chen, Pei-Ching

    Hu li za zhi The journal of nursing

    2024  Volume 70, Issue 2, Page(s) 46–57

    Abstract: Background: There is growing concern related to the recent rise in consumption of cigarettes, electronic cigarettes, and heated tobacco products. The government should pay more attention to the use of various tobacco products by university students.: ... ...

    Abstract Background: There is growing concern related to the recent rise in consumption of cigarettes, electronic cigarettes, and heated tobacco products. The government should pay more attention to the use of various tobacco products by university students.
    Purpose: Problem behavior theory was used in this study to explore the factors influencing the use of various tobacco products by university students in the Greater Taipei area.
    Methods: In this cross-sectional study, convenience sampling was used to select eight institutions of higher education in the Greater Taipei area. Eight departments recognized by the Ministry of Education were then listed on a table for use in randomizing the selection of third- and fourth-year undergraduate students. A total of 115 participants filled out the questionnaires included in the self-administered online survey. Data analysis was conducted using logistic regression.
    Results: The prevalence of tobacco-product use in the sample was 5.22%. Logistic regression analysis revealed having parents who smoked (adjusted odds ratio, AOR = 2.05), holding a positive attitude toward their parents' smoking (AOR = 4.23), having peers who smoked (AOR = 4.33), engaging in deviant behavior (AOR = 90.44), and having peers involved in deviant behavior (AOR = 103.99) to be associated with a higher likelihood of engaging in tobacco-product use.
    Conclusions / implications for practice: Family, peers and delinquency significantly influence the usage behavior of university students with regard to tobacco products. The government should allocate greater resources for tobacco harm prevention education aimed at the parents of university students. In addition, integrating tobacco harm education into campus curricula, utilizing social media for online digital education, and providing students with counseling and support measures are strategies that may help reduce the tobacco-product use among this vulnerable population.
    MeSH term(s) Humans ; Universities ; Cross-Sectional Studies ; Electronic Nicotine Delivery Systems ; Problem Behavior ; Tobacco Products ; Students/psychology
    Language Chinese
    Publishing date 2024-03-26
    Publishing country China (Republic : 1949- )
    Document type English Abstract ; Journal Article
    ISSN 0047-262X
    ISSN 0047-262X
    DOI 10.6224/JN.202404_71(2).07
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  6. Article ; Online: Integrating Genome-wide Polygenic Risk Scores with Non-genetic Models to Predict Surgical Site Infection after Total Knee Arthroplasty Using United Kingdom Biobank Data.

    Chen, Pei-Yu / Wen, Shu-Hui

    The Journal of arthroplasty

    2024  

    Abstract: Background: Prediction of the risk of developing surgical site infection (SSI) in patients following total knee arthroplasty (TKA) is of clinical importance. Genetic susceptibility is involved in developing TKA-related SSI. Previously reported models ... ...

    Abstract Background: Prediction of the risk of developing surgical site infection (SSI) in patients following total knee arthroplasty (TKA) is of clinical importance. Genetic susceptibility is involved in developing TKA-related SSI. Previously reported models for predicting SSI were constructed using non-genetic risk factors without incorporating genetic risk factors. To address this issue, we performed a genome-wide association study (GWAS) using the UK Biobank database.
    Methods: Adult patients who underwent primary TKA (n = 19,767) were analyzed and divided into SSI (n = 269) and non-SSI (n = 19,498) cohorts. Non-genetic covariates, including demographic data and preoperative comorbidities, were recorded. Genetic variants associated with SSI were identified by GWAS and included to obtain standardized polygenic risk scores (zPRS, an estimate of genetic risk). Prediction models were established through analyses of multivariable logistic regression and the receiver operating characteristic (ROC) curve.
    Results: There were four variants (rs117896641, rs111686424, rs8101598, and rs74648298) achieving genome-wide significance that were identified. The logistic regression analysis revealed seven significant risk factors: increasing zPRS, decreasing age, men, chronic obstructive pulmonary disease, diabetes mellitus, rheumatoid arthritis, and peripheral vascular disease. The areas under the ROC curve (AUC) were 0.628 and 0.708 when zPRS (model 1) and non-genetic covariates (model 2) were used as predictors, respectively. The AUC increased to 0.76 when both zPRS and non-genetic covariates (model 3) were used as predictors. A risk-prediction nomogram was constructed based on model 3 to visualize the relative effect of statistically significant covariates on the risk of SSI and predict the probability of developing SSI. Age and zPRS were the top two covariates that contributed to the risk, with younger age and higher zPRS associated with higher risks.
    Conclusion: Our GWAS identified four novel variants that were significantly associated with susceptibility to SSI following TKA. Integrating genome-wide zPRS with non-genetic risk factors improved the performance of the model in predicting SSI.
    Language English
    Publishing date 2024-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2024.05.022
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    Zs.A 2134: Show issues Location:
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  7. Article: Co-infection of

    Du, Zhu-Man / Chen, Pei

    World journal of clinical cases

    2023  Volume 11, Issue 29, Page(s) 7144–7149

    Abstract: Background: The co-infection of : Case summary: We report a case of a 40-year-old female patient with a history of contact with parrots who was diagnosed with : Conclusion: Coinfection ... ...

    Abstract Background: The co-infection of
    Case summary: We report a case of a 40-year-old female patient with a history of contact with parrots who was diagnosed with
    Conclusion: Coinfection with
    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v11.i29.7144
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  8. Article ; Online: Infrared characterization of hydrated products of glyoxal in aqueous solution.

    Chen, Pei-Rong / Chu, Li-Kang

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2023  Volume 306, Page(s) 123571

    Abstract: The simplest and most abundant dicarbonyl in the atmosphere, glyoxal ((CHO) ...

    Abstract The simplest and most abundant dicarbonyl in the atmosphere, glyoxal ((CHO)
    Language English
    Publishing date 2023-10-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2023.123571
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  9. Article ; Online: Carbon recycling with synthetic CO

    Chen, Pei-Ru / Xia, Peng-Fei

    Current opinion in biotechnology

    2023  Volume 85, Page(s) 103023

    Abstract: Carbon dioxide ( ... ...

    Abstract Carbon dioxide (CO
    MeSH term(s) Carbon Dioxide/metabolism ; Metabolic Engineering ; Heterotrophic Processes ; Carbon Cycle ; Biotechnology
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2023-11-25
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1052045-4
    ISSN 1879-0429 ; 0958-1669
    ISSN (online) 1879-0429
    ISSN 0958-1669
    DOI 10.1016/j.copbio.2023.103023
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    Zs.A 3071: Show issues Location:
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  10. Article ; Online: Does the duration matter? Effect of cochlear implantation on language development in Mandarin-speaking children with hearing loss.

    Lim, Tang Zhi / Chen, Pei-Hua

    Cochlear implants international

    2023  Volume 24, Issue 4, Page(s) 205–215

    Abstract: Objective: Several studies have shown that cochlear implantation (CI) can influence language development in children with severe-to-profound hearing loss. However, whether the age of implantation and duration of CI use influence language development ... ...

    Abstract Objective: Several studies have shown that cochlear implantation (CI) can influence language development in children with severe-to-profound hearing loss. However, whether the age of implantation and duration of CI use influence language development remains unclear, particularly in Mandarin-speaking children with hearing loss. Therefore, this study investigated the effects of CI-related variables on language development in these children.
    Methods: The present study recruited 133 Mandarin-speaking children with hearing loss, aged between 36 and 71 months chronologically, from a nonprofit organisation in Taiwan. The Revised Preschool Language Assessment (RPLA) was used to evaluate the children's language performance.
    Results: Children with hearing loss demonstrated delayed language comprehension and oral expression. Among them, 34% achieved age-appropriate language development. The duration of CI use had a significant direct effect on language-related abilities. Conversely, the age of implantation did not have a significant direct effect. Furthermore, the age of initial interventions (auditory-oral) had a significant direct effect only on language comprehension. Compared with the age of implantation, the duration of CI use was a significant mediator of language-related abilities.
    Conclusion: In Mandarin-speaking children with late CIs, the duration of CI use is a more effective mediator of language development than the age of implantation.
    MeSH term(s) Child ; Humans ; Child, Preschool ; Cochlear Implantation ; Cochlear Implants ; Speech Perception ; Deafness/surgery ; Language Development
    Language English
    Publishing date 2023-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2079515-4
    ISSN 1754-7628 ; 1467-0100
    ISSN (online) 1754-7628
    ISSN 1467-0100
    DOI 10.1080/14670100.2023.2194052
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