LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 4612

Search options

  1. Article: Effects of Natural Products on Fructose-Induced Nonalcoholic Fatty Liver Disease (NAFLD)

    Chen, Qian

    Nutrients, 9(2):96

    2017  

    Abstract: As a sugar additive, fructose is widely used in processed foods and beverages. Excessive fructose consumption can cause hepatic steatosis and dyslipidemia, leading to the development of metabolic syndrome. Recent research revealed that fructose-induced ... ...

    Abstract As a sugar additive, fructose is widely used in processed foods and beverages. Excessive fructose consumption can cause hepatic steatosis and dyslipidemia, leading to the development of metabolic syndrome. Recent research revealed that fructose-induced nonalcoholic fatty liver disease (NAFLD) is related to several pathological processes, including: (1) augmenting lipogenesis; (2) leading to mitochondrial dysfunction; (3) stimulating the activation of inflammatory pathways; and (4) causing insulin resistance. Cellular signaling research indicated that partial factors play significant roles in fructose-induced NAFLD, involving liver X receptor (LXR)α, sterol regulatory element binding protein (SREBP)-1/1c, acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), stearoyl-CoA desaturase (SCD), peroxisome proliferator–activated receptor α (PPARα), leptin nuclear factor-erythroid 2-related factor 2 (Nrf2), nuclear factor kappa B (NF-κB), tumor necrosis factor α (TNF-α), c-Jun amino terminal kinase (JNK), phosphatidylinositol 3-kinase (PI3K) and adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK). Until now, a series of natural products have been reported as regulators of NAFLD in vivo and in vitro. This paper reviews the natural products (e.g., curcumin, resveratrol, and (−)-epicatechin) and their mechanisms of ameliorating fructose-induced NAFLD over the past years. Although, as lead compounds, natural products usually have fewer activities compared with synthesized compounds, it will shed light on studies aiming to discover new drugs for NAFLD.
    Keywords fructose-induced NAFLD ; inflammatory pathways ; insulin resistance ; lipogenesis ; mitochondrial dysfunction ; natural products
    Language English
    Document type Article
    Database Repository for Life Sciences

    More links

    Kategorien

  2. Book ; Online: Osteoarthritis : Progress in Basic Research and Treatment

    Chen, Qian

    2015  

    Keywords Immunology
    Size 1 electronic resource (274 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021049963
    ISBN 9789535172437 ; 9535172433
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

  3. Book ; Conference proceedings: International Conference on Osteoporosis and Bone Research

    Chen, Qian

    [Oct 28 - 31, 2010 in Shenzhen, China]

    (Bone ; 47, Suppl. 3)

    2010  

    Event/congress International Conference on Osteoporosis and Bone Research (2010, Shenzhen)
    Author's details guest ed.: Qian Chen
    Series title Bone ; 47, Suppl. 3
    Collection
    Language English
    Size S. S331 - S458
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT016647277
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  4. Book ; Online: Osteoarthritis : Diagnosis, Treatment and Surgery

    Chen, Qian

    2012  

    Keywords Immunology
    Size 1 electronic resource (418 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021046340
    ISBN 9789535168546 ; 9535168541
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

  5. Article ; Online: Beyond Snowflakes: Heterogeneity in Nanomaterials.

    Chen, Qian

    Nano letters

    2021  Volume 22, Issue 1, Page(s) 3–5

    MeSH term(s) Nanostructures
    Language English
    Publishing date 2021-12-27
    Publishing country United States
    Document type Editorial ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.1c03400
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Review on article of effects of tenofovir alafenamide and entecavir in chronic hepatitis B virus patients.

    Sun, Yu-Tong / Chen, Qian-Qian

    World journal of hepatology

    2024  Volume 16, Issue 1, Page(s) 109–111

    Abstract: This letter comments on the article which reported that tenofovir alafenamide may increase blood lipid levels compared with entecavir in patients with chronic hepatitis B published ... ...

    Abstract This letter comments on the article which reported that tenofovir alafenamide may increase blood lipid levels compared with entecavir in patients with chronic hepatitis B published on
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2573703-X
    ISSN 1948-5182
    ISSN 1948-5182
    DOI 10.4254/wjh.v16.i1.109
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Experimental study of synergistic reinforcement of silty clay with glutinous rice paste and MICP.

    Hu, Qizhi / Chen, Qian

    PloS one

    2023  Volume 18, Issue 5, Page(s) e0284633

    Abstract: The use of microbially induced calcium carbonate precipitation (MICP) technology can improve the mechanical properties of silty clay, and glutinous rice paste can enhance microbial activity, improve the conversion rate of CaCO3 precipitation, and help ... ...

    Abstract The use of microbially induced calcium carbonate precipitation (MICP) technology can improve the mechanical properties of silty clay, and glutinous rice paste can enhance microbial activity, improve the conversion rate of CaCO3 precipitation, and help increase soil strength. An MICP solidification test of silty clay was carried out by adding different concentrations of aged glutinous rice slurry and cementing liquid, and unconfined compressive strength tests and scanning electron microscope analysis of the solidified samples were carried out. The strength growth mechanism of the glutinous rice paste was investigated, and the results revealed that glutinous rice slurry can improve the enzymatic activity of microorganisms, that is, the microorganisms can produce more urease to decompose urea, and as the amount of urease increases, the concentration of the cementing solution increases, and the calcium carbonate generated by the MICP precipitates. When the concentration of the added cooked glutinous rice slurry was 5%, the unconfined compressive strength of the soil was the largest. In addition, the scanning electron microscope analysis revealed that cooled glutinous rice slurry can be used as a bridge to generate a large amount of ineffective carbonic acid. Calcium atoms are connected together to form effective calcium carbonate, which fills in the pores of the soil as a whole, increasing the compactness of the soil and greatly improving its macroscopic mechanical strength.
    MeSH term(s) Calcium Carbonate ; Clay ; Oryza ; Urease ; Soil
    Chemical Substances Calcium Carbonate (H0G9379FGK) ; Clay (T1FAD4SS2M) ; Urease (EC 3.5.1.5) ; Soil
    Language English
    Publishing date 2023-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0284633
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Greening the BRI countries through economic and political reforms.

    Chen, Qian / Madni, Ghulam Rasool

    PloS one

    2023  Volume 18, Issue 11, Page(s) e0294967

    Abstract: Preserving the environment and promoting sustainable development are essential objectives for a state aimed at improving the standard of living for present and future generations. The depletion of natural resources and environmental degradation are ... ...

    Abstract Preserving the environment and promoting sustainable development are essential objectives for a state aimed at improving the standard of living for present and future generations. The depletion of natural resources and environmental degradation are serious concerns for policymakers worldwide. However, to fulfill its role effectively, a state must have strong institutional capacity. Studies have shown that inadequate governance and weak institutional quality are associated with environmental degradation, lower economic growth, unfavorable development outcomes, and increased inequality. Economic and political reforms are necessary to overcome these issues, while the concept of institutional reforms to save the environment is novel and hardly discussed in the earlier literature, especially in the context of BRI countries. So, this study explores the impact of economic and political reforms on the environment by applying a difference-in-differences approach to the data of 45 BRI economies from 2000 to 2022. The empirical findings reveal a negative relationship between economic and political reforms on ecological footprints, emphasizing the need for institutional reform to preserve the environment in the BRI region. Institutional reforms have a significant contribution to environmental sustainability by fostering better governance, political stability, and an environment conducive to reforms-driven decision-making. These reforms can help address the environmental challenges associated with large-scale infrastructure and economic development projects like the BRI, ultimately contributing to a more sustainable future.
    MeSH term(s) Economic Development ; Sustainable Development ; Carbon Dioxide
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0294967
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab.

    Chen, Qian / Niu, Yu-Lin

    World journal of clinical cases

    2023  Volume 11, Issue 25, Page(s) 6012–6018

    Abstract: Background: Since its initial detection in 2019, coronavirus disease 2019 (COVID-19) pneumonia has rapidly spread throughout the world in a global pandemic. However, reports of COVID-19 pneumonia among patients following kidney transplantation have been ...

    Abstract Background: Since its initial detection in 2019, coronavirus disease 2019 (COVID-19) pneumonia has rapidly spread throughout the world in a global pandemic. However, reports of COVID-19 pneumonia among patients following kidney transplantation have been limited and no uniform treatment guidelines for these patients have yet to be established.
    Case summary: Here, we report the case of a 39-year-old patient recovering from kidney transplantation who contracted perioperative COVID-19 pneumonia that was successfully controlled with oral paxlovid and a single intravenous drip infusion of tocilizumab following the discontinuation of immunosuppressive drugs.
    Conclusion: Given the rapid spread of severe acute respiratory syndrome coronavirus 2 infections, clinicians should be aware of the potential for more cases of COVID-19 among patients following kidney transplantation and be familiar with appropriate treatment options and likely clinical outcomes.
    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v11.i25.6012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Invited Commentary on "Septum Plays No Role in the Pathophysiology or Treatment of Aponeurotic Blepharoptosis" : The Role of Orbital Septum in Correcting Blepharoptosis.

    Chen, Qian / Li, Gaofeng

    Aesthetic plastic surgery

    2023  Volume 48, Issue 3, Page(s) 352–354

    MeSH term(s) Humans ; Blepharoptosis/diagnosis ; Blepharoptosis/surgery ; Blepharoplasty ; Eyelids/surgery ; Face ; Oculomotor Muscles/surgery
    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Letter
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-023-03789-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top