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Article ; Online: The impact of psychological capital on green and organizational performance: Empirical research measuring psychological and subjective health of green building industries.

Chen, Si-Xu / Tang, Yuan

2023 Volume 10, Page(s) 1030028

Abstract: Introduction: Green building (GB) technologies have been introduced to reduce the negative effect of the building and construction industry on the economy, the ecosystem, and society. A more thorough and accurate knowledge of the factors for ... ...

Abstract	Introduction: Green building (GB) technologies have been introduced to reduce the negative effect of the building and construction industry on the economy, the ecosystem, and society. A more thorough and accurate knowledge of the factors for implementation is required to stimulate the wider adoption of GB technologies. The theoretical framework for this study is developed using psychological capital (PC), self-determination theory (SDT), and green theory. The study addresses gaps in the research in this field. The effect of PC on psychological health (PH), green innovation ambidexterity (GIA), and subjective health (SH), and the impact of GIA on green performance (GP) are determined. The effect of PH and SH on organizational performance (OP) is also determined. Methods: The information for this study is collected from a variety of sources in the Chinese GB industry. The subjects for this study are Chinese employees of GB-based companies. Using a convenience sampling method, a total of 504 employees were selected. The employees' answers to a restricted, self-administered survey are used to generate the data. Results: Data from this study shows that PC has a significant effect on GIA, SH, and PH and that GIA has a substantial impact on GP. Both SH and PH significantly affect OP. Discussion: This study encourages managers in the green building industry to support fresh concepts in order to gain a competitive edge by implementing and promoting innovative cultures, especially in terms of service delivery and customer understanding, because innovation plays a critical role in these industries.
MeSH term(s)	Humans ; Construction Industry ; Diagnostic Self Evaluation ; Ecosystem ; Asian People ; Empirical Research
Language	English
Publishing date	2023-01-19
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.1030028
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Article: Design of an endoscopic OCT probe based on piezoelectric tube with quartered outside electrodes.

Hu, Jinyuan / Wu, Sujian / Shi, Guohua / Fan, Jinyu / Yu, Haoyang / Chen, Sixu

Frontiers in bioengineering and biotechnology

2024 Volume 12, Page(s) 1391630

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2024-04-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2719493-0
ISSN	2296-4185
ISSN	2296-4185
DOI	10.3389/fbioe.2024.1391630
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Article ; Online: Erratum to: Bioinformatic analysis for potential biological processes and key targets of heart failure-related stroke.

Liu, Chiyu / Chen, Sixu / Zhang, Haifeng / Chen, Yangxin / Gao, Qingyuan / Chen, Zhiteng / Liu, Zhaoyu / Wang, Jingfeng

Journal of Zhejiang University. Science. B

2024 Volume 25, Issue 4, Page(s) 359

Abstract: The original version of this article (Liu et al., 2021) unfortunately contained a mistake: statement of equal contribution is missing. This correction article shows that Chiyu LIU and Sixu CHEN contributed equally to this work. The original article has ... ...

Abstract	The original version of this article (Liu et al., 2021) unfortunately contained a mistake: statement of equal contribution is missing. This correction article shows that Chiyu LIU and Sixu CHEN contributed equally to this work. The original article has been corrected.
Language	English
Publishing date	2024-04-05
Publishing country	China
Document type	Journal Article
ZDB-ID	2247290-3
ISSN	1862-1783 ; 1673-1581
ISSN (online)	1862-1783
ISSN	1673-1581
DOI	10.1631/jzus.B20e0544
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Article: Preparation and characterization of PLA‐lemon essential oil nanofibrous membranes for the preservation of Mongolian cheese

Chen, Sixu / Wang, Pengyang / Meng, Wenzhao / Wu, Lingling / Saldaña, Marleny D. A. / Fan, Xiaoli / Jin, Ye / Sun, Wenxiu

Journal of food processing and preservation. 2022 May, v. 46, no. 5

2022

Abstract: Mongolian cheese is easily contaminated by foodborne microorganisms, causing foodborne diseases and endangering public health. This study aimed to fabricate and characterize polylactic acid nanofibrous membranes loaded with lemon essential oil (PLNM), ... ...

Abstract	Mongolian cheese is easily contaminated by foodborne microorganisms, causing foodborne diseases and endangering public health. This study aimed to fabricate and characterize polylactic acid nanofibrous membranes loaded with lemon essential oil (PLNM), estimating their potential to be used as a novel antibacterial material for limiting the development of pathogenic microorganisms on the cheese surface. Results showed that the fibrous diameter, water contact angle, and cumulative release of the PLNM increased with lemon essential oil incorporation. Meanwhile, the PLNM can inhibit four pathogenic microorganisms and two spoilage microorganisms. According to TVC, we found that the PLNM can effectively inhibit microorganisms within the safety threshold for 8 days at 25 ± 1°C, and extended the shelf life of Mongolian cheese by 2 days. The PLNM had an excellent antibacterial effect and the potential for application in Mongolian cheese preservation. PRACTICAL APPLICATIONS: As a characteristic dairy product of Inner Mongolia, Mongolian cheese is popular because of its unique flavor. However, cheese's susceptibility to microbes has reduced its sales radius. The polylactic acid nanofibrous membranes loaded with lemon essential oil (PLNM) prepared in this study can effectively inhibit the growth of pathogenic microorganisms on the cheese surface. Results showed that PLNM effectively extended the shelf life of Mongolian cheese to 8 days at 25 ± 1°C.
Keywords	antibacterial properties ; antibiotics ; cheeses ; contact angle ; essential oils ; flavor ; lemons ; nanofibers ; polylactic acid ; public health ; shelf life ; spoilage ; China
Language	English
Dates of publication	2022-05
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	243448-9
ISSN	1745-4549 ; 0145-8892
ISSN (online)	1745-4549
ISSN	0145-8892
DOI	10.1111/jfpp.16552
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Article ; Online: A facile and smart strategy to enhance bone regeneration with efficient vitamin D

Ye, Shuxi / Wen, Jing / Ye, Wen-Hao / Li, Zhen / Huang, Xiaomeng / Chen, Sixu / Ma, Jian-Chao / Wu, Yaohong / Chen, Rongchun / Cui, Zhong-Kai

Journal of controlled release : official journal of the Controlled Release Society

2024 Volume 370, Page(s) 140–151

Abstract: The spontaneous healing of critical-sized bone defects is often limited, posing an increased risk of complications and suboptimal outcomes. Osteogenesis, a complex process central to bone formation, relies significantly on the pivotal role of osteoblasts. ...

Abstract	The spontaneous healing of critical-sized bone defects is often limited, posing an increased risk of complications and suboptimal outcomes. Osteogenesis, a complex process central to bone formation, relies significantly on the pivotal role of osteoblasts. Despite the well-established osteogenic properties of vitamin D
Language	English
Publishing date	2024-04-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	632533-6
ISSN	1873-4995 ; 0168-3659
ISSN (online)	1873-4995
ISSN	0168-3659
DOI	10.1016/j.jconrel.2024.04.033
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Article: The increase in bone resorption in early-stage type I diabetic mice is induced by RANKL secreted by increased bone marrow adipocytes

Yang, Jiazhi / Chen, Sixu / Zong, Zhaowen / Yang, Lei / Liu, Daocheng / Bao, Quanwei / Du, Wenqiong

Biochemical and biophysical research communications. 2020 Apr. 30, v. 525, no. 2

2020

Abstract: Bone marrow adipose tissue (BMAT) has recently been found to induce osteoclastogenesis by secreting RANKL. Although Type 1 diabetes mellitus (T1DM) has been reported to be associated with increased BMAT and bone loss, little is known about the ... ...

Abstract	Bone marrow adipose tissue (BMAT) has recently been found to induce osteoclastogenesis by secreting RANKL. Although Type 1 diabetes mellitus (T1DM) has been reported to be associated with increased BMAT and bone loss, little is known about the relationship between BMAT and osteoclasts in T1DM. We studied the role of BMAT in the alterations of osteoclast activities in early-stage T1DM, by using a streptozotocin-induced T1DM mouse model. Our results showed that osteoclast activity was enhanced in the long bones of T1DM mice, accompanied by increased protein expression of RANKL. However, RANKL mRNA levels in bone tissues of T1DM mice remained unchanged. Meanwhile, we found that BMAT was significantly increased in the long bones of T1DM mice, and both mRNA and protein levels of RANKL were elevated in the diabetic BMAT. More importantly, RANKL protein was mainly expressed on the cell membranes of the increased adipocytes, most of which were located next to the metaphyseal region. These results suggest that the enhanced bone resorption in early-stage diabetic mice is induced by RANKL derived from BMAT rather than the bone tissue itself.
Keywords	adipocytes ; adipose tissue ; bone formation ; bone marrow ; bone resorption ; insulin-dependent diabetes mellitus ; mice ; osteoclasts ; protein synthesis ; research
Language	English
Dates of publication	2020-0430
Size	p. 433-439.
Publishing place	Elsevier Inc.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	205723-2
ISSN	0006-291X ; 0006-291X
ISSN (online)	0006-291X
ISSN	0006-291X
DOI	10.1016/j.bbrc.2020.02.079
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Article: Development of sunlight‐driven photodynamic inactivation film to extend the shelf life of chilled mutton

Wang, Pengyang / Saldaña, Marleny D. A. / Hao, Yu / Chen, Sixu / Wu, Jianxin / Jin, Ye / Sun, Wenxiu

Journal of food processing and preservation. 2021 Oct., v. 45, no. 10

2021

Abstract: In this study, sunlight‐driven photodynamic inactivation film (PIF) was created. It aimed to inhibit the growth of pathogenic microorganisms and extend the shelf life of chilled mutton. Polyvinyl alcohol film was used as the substrate, on which 3,3′,4,4′‐ ...

Abstract	In this study, sunlight‐driven photodynamic inactivation film (PIF) was created. It aimed to inhibit the growth of pathogenic microorganisms and extend the shelf life of chilled mutton. Polyvinyl alcohol film was used as the substrate, on which 3,3′,4,4′‐benzophenone tetracarboxylic dianhydride was grafted by using polyphosphoric acid. The PIF can effectively generate 2,306 μg/g reactive oxygen species under sunlight driving and can be reused for three times. The antibacterial test showed that it can inhibit five pathogenic microorganisms. Later we applied the PIF to chilled mutton. Microbiological analysis results showed the PIF can effectively inhibit the growth of microorganisms on the mutton surface within the safety threshold for 15 days. In addition, total volatile base nitrogen reached the maximum threshold (20 mg/100 g) on the 14th day, and extended the shelf life to 15 days. The PIF had an excellent sterilization effect and the potential of application prospects as responsive packaging. PRACTICAL APPLICATIONS: Chilled mutton is one of the most popular convenient meat products, but microbial pollution greatly shortens its shelf life. The photodynamic inactivation film (PIF) prepared in this study can effectively inhibit the growth of selected foodborne pathogenic microorganisms and spoilage microorganisms that cause its spoilage. The storage experiments of chilled mutton further proved that PIF can effectively prolong the shelf life of chilled mutton.
Keywords	mutton ; pollution ; polyvinyl alcohol ; reactive oxygen species ; shelf life ; solar radiation ; spoilage ; total volatile basic nitrogen
Language	English
Dates of publication	2021-10
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	243448-9
ISSN	1745-4549 ; 0145-8892
ISSN (online)	1745-4549
ISSN	0145-8892
DOI	10.1111/jfpp.15814
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Article ; Online: First-aid Training for Combatants Without Systematic Medical Education Experience on the Battlefield: Establishment and Evaluation of the Curriculum in China.

Qin, Hao / Liu, Daocheng / Chen, Sixu / Lyv, Mingrui / Yang, Lei / Bao, Quanwei / Zong, Zhaowen

Military medicine

2020 Volume 185, Issue 9-10, Page(s) e1822–e1828

Abstract: Introduction: For combatants without systematic medical education experience (CSMEE), it is necessary to participate in first-aid on the battlefield, but currently there is no effective training curriculum for CSMEE in Chinese military.: Materials and ...

Abstract	Introduction: For combatants without systematic medical education experience (CSMEE), it is necessary to participate in first-aid on the battlefield, but currently there is no effective training curriculum for CSMEE in Chinese military. Materials and methods: A list of first-aid techniques based on expert consensus was formed, and then a curriculum was established according to the list. The effectiveness of the curriculum was further evaluated by comparing the scores among group A (the reserve officers trained by this curriculum), group B (the reserve officers in the military medical college trained by professional medic training system), and group C (the fresh officers trained by the Outline of Military Training and Assessment of Chinese military), through a 5-station assessment in a simulated battlefield environment, which included the following 5 techniques: tourniquet for massive extremities hemorrhage, thyrocricocentesis, thoracentesis, fixation of long bone fractures, and wound dressing with hemostatic bandage. Results: The training curriculum entitled "Implementation and Assessment Standards of First-aid Training for Combatants on the Battlefield" was established. The comparison of average scores in the 5-station assessment showed that group A had better scores than group C in tourniquet for massive extremity hemorrhage, thyrocricocentesis, and thoracentesis, with no significant differences compared with group B. Also, no significant difference between groups A and B in overall completion time and overall scores was observed, whereas an excellent candidate rate in overall score of group B was better than that of group A (87.4% vs. 80.9%, χ2 = 4.40, p = 0.036), and group A was better than group C (80.9% vs. 37.5%, χ2 = 62.01, p < 0.001). Conclusion: The established training curriculum is indeed effective, which improved the CSMEE's first-aid capacity on the battlefield, and is equivalent to the level of medics.
MeSH term(s)	China ; Curriculum ; Education, Medical ; First Aid ; Humans ; Tourniquets
Language	English
Publishing date	2020-06-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	391061-1
ISSN	1930-613X ; 0026-4075
ISSN (online)	1930-613X
ISSN	0026-4075
DOI	10.1093/milmed/usaa152
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Article ; Online: The increase in bone resorption in early-stage type I diabetic mice is induced by RANKL secreted by increased bone marrow adipocytes.

Yang, Jiazhi / Chen, Sixu / Zong, Zhaowen / Yang, Lei / Liu, Daocheng / Bao, Quanwei / Du, Wenqiong

Biochemical and biophysical research communications

2020 Volume 525, Issue 2, Page(s) 433–439

Abstract	Bone marrow adipose tissue (BMAT) has recently been found to induce osteoclastogenesis by secreting RANKL. Although Type 1 diabetes mellitus (T1DM) has been reported to be associated with increased BMAT and bone loss, little is known about the relationship between BMAT and osteoclasts in T1DM. We studied the role of BMAT in the alterations of osteoclast activities in early-stage T1DM, by using a streptozotocin-induced T1DM mouse model. Our results showed that osteoclast activity was enhanced in the long bones of T1DM mice, accompanied by increased protein expression of RANKL. However, RANKL mRNA levels in bone tissues of T1DM mice remained unchanged. Meanwhile, we found that BMAT was significantly increased in the long bones of T1DM mice, and both mRNA and protein levels of RANKL were elevated in the diabetic BMAT. More importantly, RANKL protein was mainly expressed on the cell membranes of the increased adipocytes, most of which were located next to the metaphyseal region. These results suggest that the enhanced bone resorption in early-stage diabetic mice is induced by RANKL derived from BMAT rather than the bone tissue itself.
MeSH term(s)	Adipocytes/metabolism ; Adipocytes/pathology ; Animals ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Bone Resorption/etiology ; Bone Resorption/metabolism ; Bone Resorption/pathology ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/metabolism ; Diabetes Mellitus, Type 1/pathology ; Male ; Mice ; Mice, Inbred C57BL ; RANK Ligand/analysis ; RANK Ligand/metabolism
Chemical Substances	RANK Ligand ; Tnfsf11 protein, mouse
Language	English
Publishing date	2020-02-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	205723-2
ISSN	1090-2104 ; 0006-291X ; 0006-291X
ISSN (online)	1090-2104 ; 0006-291X
ISSN	0006-291X
DOI	10.1016/j.bbrc.2020.02.079
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Article: TCF12 regulates the TGF-β/Smad2/3 signaling pathway to accelerate the progression of osteoarthritis by targeting CXCR4.

Zheng, Hui / Fang, Jianli / Lu, Wei / Liu, Youhui / Chen, Sixu / Huang, Guangxin / Zou, Yuming / Hu, Shu / Zheng, Yongxu / Fang, Hang / Zhang, Rongkai

Journal of orthopaedic translation

2023 Volume 44, Page(s) 35–46

Abstract: Objective: Osteoarthritis (OA), which involves total joint damage and dysfunction, is a leading cause of disability worldwide. However, its exact pathogenesis remains unclear. Here, we identified TCF12 as an important regulator of the progression of OA.! ...

Abstract	Objective: Osteoarthritis (OA), which involves total joint damage and dysfunction, is a leading cause of disability worldwide. However, its exact pathogenesis remains unclear. Here, we identified TCF12 as an important regulator of the progression of OA. Methods: qRT-PCR, immunoblotting and immunohistochemistry (IHC) were used to detect the expression level of TCF12. The interaction of TCF12 with its downstream factor CXCR4 was assessed by Western blotting, immunofluorescence, qRT-PCR and luciferase assays. A mouse model was generated to examine the functions and mechanism of TCF12 in vivo. Result: TCF12 expression was upregulated in chondrocytes stimulated with IL-1β and osteoarthritic chondrocytes. TCF12 upregulates the expression of CXCR4 and leads to dysfunction of the TGF-β signaling pathway. Furthermore, knockdown of TCF12 alleviated cartilage damage in a mouse model generated by destabilization of the medial meniscus (DMM). Conclusion: TCF12 aggravates the progression of OA by targeting CXCR4 and then activating the TGF-β signaling pathway, suggesting that TCF12 may be a new target for the treatment of OA. The translational potential of this article: Transcription Factor 12(TCF12), is known to regulate cell development and differentiation, It has been widely studied in various organs and diseases, but its role in OA remains unclear. Here, we identified Transcription Factor 12(TCF12) as an important regulator mediating chondrocyte senescence and cartilage extracellular matrix degradation indicating its role in OA. We found that TCF12 expression was upregulated both locally and systemically as OA advanced in patients with OA, and in mice after DMM surgery to induce OA. TCF12 expression caused striking progressive articular cartilage damage, synovial hyperplasia in OA mice, and remarkably, it was relieved by intra-articular administration of mutant mouse TCF12 lentiviral vector (shTCF12). Furthermore, TCF12 upregulated the expression of CXCR4, leading to exacerbation of experimental OA partially through activation of TGF-β signaling in chondrocytes. TCF12 expression was upregulated in chondrocytes treated with IL-1β and osteoarthritic chondrocytes. Our findings established an essential role of TCF12 in chondrocyte senescence and cartilage extracellular matrix degradation during OA, and identified intra-articular injection of TCF12 as a potential therapeutic strategy for OA prevention and treatment.
Language	English
Publishing date	2023-12-27
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2747531-1
ISSN	2214-031X
ISSN	2214-031X
DOI	10.1016/j.jot.2023.11.006
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