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  1. Article: Multiple criteria decision analytic methods in management with T-spherical fuzzy information.

    Chen, Ting-Yu

    Artificial intelligence review

    2023  , Page(s) 1–71

    Abstract: With a focus on T-spherical fuzzy (T-SF) sets, the aim of this paper is to create a split-new appraisal mechanism and an innovative decision analytic method for use with multiple-criteria assessment and selection in uncertain situations. The T-SF frame ... ...

    Abstract With a focus on T-spherical fuzzy (T-SF) sets, the aim of this paper is to create a split-new appraisal mechanism and an innovative decision analytic method for use with multiple-criteria assessment and selection in uncertain situations. The T-SF frame is the latest recent advancement in fuzzy settings and uses four facets (consisting of membership grades of positivity, neutrality, negativity, and refusal) to elucidate complex uncertainties, thereby evidently reducing information loss, in anticipation of fully manifesting indistinct and equivocal information. This paper adds to the body of knowledge regarding multiple criteria choice modeling by raising T-SF correlation-oriented measurements connected to the fixed and displaced ideal/anti-ideal benchmarks and by creating an approachable appraisal mechanism for advancing a T-SF decision analytic methodology. Consider, in particular, the performance ratings of available options in terms of judging criteria under the T-SF type of uncertainties. This research gives correlation-oriented measurements focusing on two varieties of maximum and square root functions in T-SF situations, which serve as a solid foundation for an efficacious appraisal mechanism from two views of anchored judgments corresponding to the fixed and displaced benchmarks. The T-SF Minkowski distance index is generated to integrate the outranking and outranked identifiers relying on correlation-oriented measurements for figuring out the local outranking and outranked indices. The T-SF decision analytic procedures are constructed using a new appraisal significance index that is founded on certain valuable insights of correlation-oriented maximizing and minimizing indices as well as global outranking and outranked indices. Additionally, a concrete location selection dilemma is dealt with in this research to showcase the applicability and efficiency of the suggested T-SF decision analytic methodology. Sensitivity analyses and comparative studies are carried out to investigate substantial modifications in pertinent parameters and to confirm the robustness of the predominance relationships among the available options. The suggested approaches are adaptable, flexible, and reliable, according to the application outcomes and comparison findings. This research provides four scientific contributions: (1) the utilization of T-SF correlation coefficients as the basis for prioritization analysis involving multiple criteria assessments, (2) the evolution of the T-SF Minkowski distance index to model outranking decision-making processes, (3) the creation of a reliable appraisal mechanism based on T-SF correlation-oriented measurements for intelligent decision support, and (4) the advancement of computational tools and procedures (e.g., correlation-oriented maximizing and minimizing indices, global outranking and outranked indices, and appraisal significance indices) to perform the decision analytic procedure in T-SF settings. In terms of managerial implications, the solution findings support the employment of the fixed ideal/anti-ideal benchmarking mechanism, as its measurements and indices are easy to operate and suitably sensitive. Next, in practical implementations of the T-SF decision analytic procedure, it is advised to utilize the T-SF Manhattan distance index for calculating convenience. Finally, the T-SF decision analytic techniques offer fundamental ideas and measurements appropriate for manipulating T-SF information in complex decision situations, thereby increasing the application potential in the area of decision-making with information uncertainty.
    Language English
    Publishing date 2023-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1479828-1
    ISSN 1573-7462 ; 0269-2821
    ISSN (online) 1573-7462
    ISSN 0269-2821
    DOI 10.1007/s10462-023-10461-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: An Argument-Based Validation of an Asynchronous Written Interaction Task.

    Chen, Ting

    Frontiers in psychology

    2022  Volume 13, Page(s) 889488

    Abstract: Interactional competence has attracted increasing attention due to its significance for language users. Previous studies concerning interactional competence mainly focus on synchronous interaction tasks, while the utilization of asynchronous interaction ... ...

    Abstract Interactional competence has attracted increasing attention due to its significance for language users. Previous studies concerning interactional competence mainly focus on synchronous interaction tasks, while the utilization of asynchronous interaction tasks is relatively under-explored despite the importance of asynchronous interaction in real life. Taking the "Responding To Forum Posts" (RTFP) task used in the International Undergraduate English Entrance Examination (IUEEE) at Shanghai Jiao Tong University (SJTU) as an example, the study aims to validate the use of asynchronous interaction tasks in the assessment of learner's interactional competence. 49 students' performances on the RTFP task were collected through a prototype test of the IUEEE in 2021. The data were analyzed through content analysis, analysis of variance, and ordinal logistic regression. The results showed that the task elicited a wide range of interactional features and test-takers at different proficiency levels differed significantly in the variety of features and the amount of emotion-based interaction. The study also found significant correlations between some of the features and test takers' overall performance on interactional competence. The study has provided validity evidence for the RTFP task in the assessment of interactional competence and thrown light on the construct of asynchronous written interactional competence.
    Language English
    Publishing date 2022-06-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.889488
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Research progress in the relationship between PREX1 gene and tumor pathogenesis

    Chen Ting, Zhou Yu

    Xin yixue, Vol 54, Iss 12, Pp 845-

    2023  Volume 848

    Abstract: Phosphatidylinositol-3, 4, 5-triphosphate-dependent Rac exchange factor 1 (PREX1) is a coding gene that is abnormally expressed in a variety of tumors. As a guanine nucleotide exchange factor (RacGEF) of small GTP binding protein Rac1, PREX1 gene-encoded ...

    Abstract Phosphatidylinositol-3, 4, 5-triphosphate-dependent Rac exchange factor 1 (PREX1) is a coding gene that is abnormally expressed in a variety of tumors. As a guanine nucleotide exchange factor (RacGEF) of small GTP binding protein Rac1, PREX1 gene-encoded protein can form PREX1/Rac pathway through activating Rac1, crosstalk with a variety of classical signaling pathways, participate in the regulation of various receptor reactions in the tumor process, affect the epithelial-mesenchymal transformation process of the tumor microenvironment and play a role in tumor proliferation,metastasis and prognosis.
    Keywords phosphatidylinositol-3, 4, 5-triphosphate-dependent rac exchange factor 1 gene|signaling pathway|epithelial-mesenchymal transformation|tumor|pathogenesis ; Medicine ; R
    Language Chinese
    Publishing date 2023-12-01T00:00:00Z
    Publisher Editorial Office of Journal of New Medicine
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online: On the Importance of Noise Scheduling for Diffusion Models

    Chen, Ting

    2023  

    Abstract: We empirically study the effect of noise scheduling strategies for denoising diffusion generative models. There are three findings: (1) the noise scheduling is crucial for the performance, and the optimal one depends on the task (e.g., image sizes), (2) ... ...

    Abstract We empirically study the effect of noise scheduling strategies for denoising diffusion generative models. There are three findings: (1) the noise scheduling is crucial for the performance, and the optimal one depends on the task (e.g., image sizes), (2) when increasing the image size, the optimal noise scheduling shifts towards a noisier one (due to increased redundancy in pixels), and (3) simply scaling the input data by a factor of $b$ while keeping the noise schedule function fixed (equivalent to shifting the logSNR by $\log b$) is a good strategy across image sizes. This simple recipe, when combined with recently proposed Recurrent Interface Network (RIN), yields state-of-the-art pixel-based diffusion models for high-resolution images on ImageNet, enabling single-stage, end-to-end generation of diverse and high-fidelity images at 1024$\times$1024 resolution (without upsampling/cascades).

    Comment: tech report
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Graphics ; Computer Science - Machine Learning ; Computer Science - Multimedia
    Subject code 006
    Publishing date 2023-01-26
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Evolved distance measures for circular intuitionistic fuzzy sets and their exploitation in the technique for order preference by similarity to ideal solutions.

    Chen, Ting-Yu

    Artificial intelligence review

    2022  Volume 56, Issue 7, Page(s) 7347–7401

    Abstract: Circular intuitionistic fuzzy (C-IF) sets are an up-and-coming tool for enforcing indistinct and imprecise information in variable and convoluted decision-making situations. C-IF sets, as opposed to typical intuitionistic fuzzy sets, are better suited ... ...

    Abstract Circular intuitionistic fuzzy (C-IF) sets are an up-and-coming tool for enforcing indistinct and imprecise information in variable and convoluted decision-making situations. C-IF sets, as opposed to typical intuitionistic fuzzy sets, are better suited for identifying the evaluation data with uncertainty in intricate realistic decision situations. The architecture of the technique for order preference by similarity to ideal solutions (TOPSIS) provides powerful evaluation tools to aid decision-making in intuitionistic fuzzy conditions. To address appraisal issues associated with decision analysis involving extremely convoluted information, this paper propounds a novel C-IF TOPSIS approach in the context of C-IF uncertainty. This research makes three significant contributions. First, based on the three- and four-term operating rules, this research introduces C-IF Minkowski distance measures, which are new generalized representations of distance metrics applicable to C-IF values and C-IF sets. Such general C-IF distance metrics can alleviate the constraints of established C-IF distance measures, provide usage resiliency through parameter settings, and broaden the applicability of metric analysis. Second, unlike existing C-IF TOPSIS methods, this research fully utilizes C-IF information characteristics and extends the core structure of the classic TOPSIS to C-IF contexts. With the newly developed C-IF Minkowski metrics, this study faithfully demonstrates the trade-off evaluation and compromise decision rules in the TOPSIS framework. Third, this research builds on the core strengths of the pioneered C-IF Minkowski distance measures to create innovative C-IF TOPSIS techniques utilizing four different combinations, including displaced and fixed anchoring frameworks, as well as three- and four-term representations. Such a refined C-IF TOPSIS methodology can assist decision-makers in proactively addressing increasingly sophisticated decision-making problems in practical settings. Finally, this research employs two innovative prioritization algorithms to address a site selection issue of large-scale epidemic hospitals to illustrate the superior capabilities of the C-IF TOPSIS methodology over some current related approaches.
    Language English
    Publishing date 2022-12-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1479828-1
    ISSN 1573-7462 ; 0269-2821
    ISSN (online) 1573-7462
    ISSN 0269-2821
    DOI 10.1007/s10462-022-10318-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Red blood cell folate and benign prostatic hyperplasia: results from the NHANES 2001-2008.

    Chen, TingTing / Huang, YuanPeng

    The aging male : the official journal of the International Society for the Study of the Aging Male

    2024  Volume 27, Issue 1, Page(s) 2336625

    Abstract: Background: Benign prostatic hyperplasia (BPH) affects 30% of men worldwide, folate is essential for life. However, few studies have investigated the relationship between folate levels and BPH. The present study aims to explore the relationship between ... ...

    Abstract Background: Benign prostatic hyperplasia (BPH) affects 30% of men worldwide, folate is essential for life. However, few studies have investigated the relationship between folate levels and BPH. The present study aims to explore the relationship between red blood cell (RBC) folate, a better indicator of long-term folate intake, and BPH in United States (US) men.
    Methods: We used statistics from four cycles of the "National Health and Nutrition Examination Survey" (NHANES2001-2008), RBC folate data come from laboratory data and BPH date come from questionnaire data. A multivariate conditional logistic regression model and subgroup analysis were using to assess the association between RBC folate and BPH.
    Results: 647 males from four survey cycles in the NHANES2001-2008, of which, 574 men (88.7%) had BPH. After adjusting for potential confounders, a considerable correlation was observed between RBC folate and BPH; With the first quintiles of RBC folate as the reference, multivariable-adjusted odds ratios (ORs) and confidence intervals (95% CIs) of the second, third, fourth, and the highest quintiles were 1.19 (0.58 ∼ 2.44), 1.39 (0.65 ∼ 2.97), 2.27 (0.96 ∼ 5.39), 2.26 (1.35 ∼ 3.76) and 5.37 (1.85 ∼ 15.59), respectively.
    Conclusions: Individuals with high levels of RBC folate were associated with an increased risk of self-reported benign prostatic hyperplasia of US men.
    MeSH term(s) Humans ; Male ; Prostatic Hyperplasia/blood ; Prostatic Hyperplasia/epidemiology ; Folic Acid/blood ; Nutrition Surveys ; Middle Aged ; United States/epidemiology ; Erythrocytes/chemistry ; Erythrocytes/metabolism ; Aged ; Adult ; Logistic Models ; Risk Factors
    Chemical Substances Folic Acid (935E97BOY8)
    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2108146-3
    ISSN 1473-0790 ; 1368-5538
    ISSN (online) 1473-0790
    ISSN 1368-5538
    DOI 10.1080/13685538.2024.2336625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: WOUND MANAGEMENT WITH AND WITHOUT MODIFIED CHOUKROUN'S PLATELET-RICH FIBRIN IN RESCUED FORMOSAN PANGOLINS (

    Chen, Ting-Yu

    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians

    2021  Volume 52, Issue 2, Page(s) 779–786

    Abstract: Trauma is a key threat to wild Formosan pangolins ( ...

    Abstract Trauma is a key threat to wild Formosan pangolins (
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2174930-9
    ISSN 1937-2825 ; 1042-7260
    ISSN (online) 1937-2825
    ISSN 1042-7260
    DOI 10.1638/2017-0252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: CRISPR/Cas12a trans-cleavage triggered by cleavage ligation of dumbbell DNA for specific detection of human 8-oxoguanine DNA glycosylase activity.

    Cui, Chenyu / Chen, Ting-Hsuan

    Mikrochimica acta

    2023  Volume 190, Issue 12, Page(s) 468

    Abstract: Human 8-oxoguanine DNA glycosylase (hOGG1) is an essential enzyme that recognizes and removes 8-oxoguanine (8-oxoG), a common DNA oxidative damage caused by reactive oxygen species, to maintain genomic integrity of living organisms. Abnormal expression ... ...

    Abstract Human 8-oxoguanine DNA glycosylase (hOGG1) is an essential enzyme that recognizes and removes 8-oxoguanine (8-oxoG), a common DNA oxidative damage caused by reactive oxygen species, to maintain genomic integrity of living organisms. Abnormal expression of hOGG1 has been proved to be associated with different diseases such as cancer and neurogenerative disorders, making it a potential biomarker and therapeutic target. In this study, we report the development of  a novel strategy for detecting hOGG1 activity based on CRISPR/Cas12a trans-cleavage triggered by cleavage ligation of a dumbbell DNA probe (DBP) designed with a 3' overhang and an 8-oxoG modification. When hOGG1 is present, it cleaves the DBP at the 8-oxoG site, forming a 5' phosphate termini and exposing a single-strand region allowing complementary to the 3' overhang. After hybridization, the 3' and 5' termini in the juxtaposition are ligated by T4 DNA ligase, leading to a closed DBP for CRISPR/Cas12a-crRNA to recognize and initiate the trans-cleavage of the surrounding ssDNAs with fluorophore and quencher. The method achieves a limit of detection (LOD) with 370 μU/mL and high selectivity. Furthermore, it demonstrates a good compatibility for detecting hOGG1 activity in cell lysates, suggesting a good performance for further application in disease diagnosis and scientific research.
    MeSH term(s) Humans ; CRISPR-Cas Systems ; DNA Glycosylases ; DNA/genetics ; DNA/metabolism ; Guanine
    Chemical Substances 8-hydroxyguanine (5614-64-2) ; DNA Glycosylases (EC 3.2.2.-) ; DNA (9007-49-2) ; Guanine (5Z93L87A1R)
    Language English
    Publishing date 2023-11-16
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-023-06050-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Reply to Kim et al. Acute Hemorrhagic Encephalomyelitis in the Context of MOG Antibody-Associated Disease. Comment on "Chen et al. Rapid Progressive Fatal Acute Hemorrhagic Encephalomyelitis.

    Chen, Hung-Chieh / Chen, Ting-Bin

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 23

    Abstract: We want to express our appreciation for the insightful comments [ ... ]. ...

    Abstract We want to express our appreciation for the insightful comments [...].
    Language English
    Publishing date 2023-11-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13233549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Microsurgical complication associated with vaccine-induced immune thrombotic thrombocytopenia (VITT): A case report.

    Hung, Chen-Ting / Hsu, Honda

    Medicine

    2023  Volume 102, Issue 7, Page(s) e33013

    Abstract: Rationale: The use of ChAdOx1 nCoV-19 (Astra Zeneca) vaccine has proven beneficial, but in a limited number of the general population, it was found to be associated with vaccine-induced immune thrombotic thrombocytopenia (VITT). However, there have been ...

    Abstract Rationale: The use of ChAdOx1 nCoV-19 (Astra Zeneca) vaccine has proven beneficial, but in a limited number of the general population, it was found to be associated with vaccine-induced immune thrombotic thrombocytopenia (VITT). However, there have been no reports of this complication occurring in a microsurgical free tissue transfer.
    Patient concerns: A 49-year-old man developed an acute myocardial infarction 3 weeks after receiving his first dose of ChAdOx1 nCoV-19 in June 2021. Three months later, he presented with right third toe wet gangrene with extension into the plantar foot nine days after receiving his second dose of ChAdOx1 nCoV-19 vaccine.
    Diagnosis: Based on recent exposure to vaccination, the timing of inoculation before the development of his symptoms, and serology tests (platelet, D-dimer, and anti-PF4 antibodies), the patient was diagnosed with VITT.
    Interventions: Fasciectomy and sequestrectomy were performed for wound bed preparation. Limb salvage was done using free vastus lateralis muscle flap and skin graft for reconstruction.
    Outcome: The flap was complicated by persistent microthrombi leading to superficial necrosis without vascular pedicle compromise. Repeated debridement of the superficial necrosis was done. Three months after the development of VITT, no further new superficial necrosis was seen. A well-contoured flap was seen 5 months after the initial surgery.
    Lessons: We believe this is the first case describing microthrombi in the free flap due to VITT after microsurgical reconstruction. Patients and surgeons should be advised of this possible risk when contemplating microsurgery once VITT has developed after ChAdOx1 nCoV-19 administration.
    MeSH term(s) Humans ; Male ; Middle Aged ; ChAdOx1 nCoV-19/adverse effects ; Free Tissue Flaps ; Purpura, Thrombocytopenic, Idiopathic/chemically induced ; Thrombosis/chemically induced ; COVID-19/prevention & control
    Chemical Substances ChAdOx1 nCoV-19 (B5S3K2V0G8)
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000033013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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