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  1. Article: [Pembrolizumab plus nab-paclitaxel and platinum as first-line treatment in patients with recurrent or metastatic head and neck squamous-cell carcinoma: a prospective phaseⅡstudy].

    Chen, X R / Xie, Z C / Lu, H Z / Yang, J L / Gui, L

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2024  Volume 59, Issue 4, Page(s) 321–328

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Female ; Humans ; Aged ; Squamous Cell Carcinoma of Head and Neck/drug therapy ; Platinum ; Prospective Studies ; Paclitaxel/therapeutic use ; Head and Neck Neoplasms/drug therapy ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Albumins ; Antibodies, Monoclonal, Humanized
    Chemical Substances 130-nm albumin-bound paclitaxel ; pembrolizumab (DPT0O3T46P) ; Platinum (49DFR088MY) ; Paclitaxel (P88XT4IS4D) ; Albumins ; Antibodies, Monoclonal, Humanized
    Language Chinese
    Publishing date 2024-04-08
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20231013-00143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The diagnostic accuracy of the IFLIP system for binocular visual function anomalies assessment.

    Wang, J-Y / Chen, X-R / Peng, S / Zhu, L

    European review for medical and pharmacological sciences

    2023  Volume 27, Issue 12, Page(s) 5620–5626

    Abstract: Objective: This study aimed to evaluate the diagnostic accuracy of the intelligent flipper (IFLIP) system in identifying binocular vision anomalies.: Patients and methods: This study comprised 70 participants aged 18 to 22. Participants underwent ... ...

    Abstract Objective: This study aimed to evaluate the diagnostic accuracy of the intelligent flipper (IFLIP) system in identifying binocular vision anomalies.
    Patients and methods: This study comprised 70 participants aged 18 to 22. Participants underwent comprehensive eye assessments, including measurement of visual acuity, refraction, far and near cover test, stereopsis, and worth four dot test. The manual accommodation amplitude and facility, as well as the IFLIP system test, were also evaluated. The correlation between the indices of the IFLIP and manual accommodation tests was analyzed using multiple regression models, and the diagnostic ability of the IFLIP was characterized using Receiver Operating Curve (ROC) analysis. The significance level was 0.05.
    Results: The mean age of the 70 participants was 20.03±0.78 years. The mean manual and IFLIP accommodation facilities were 12.00±3.70 cycle per minute (CPM) and 10.01±2.77 CPM, respectively. No correlation was found between the indices of the IFLIP system and manual accommodative amplitude. However, the regression model showed that the contraction/relaxation ratio of the IFLIP system was positively correlated to the manual accommodation facility, and the average contraction time was negatively correlated with the manual accommodation facility. The ROC analysis proposed a cut-off of 10.15 CPM monocularly for the IFLIP accommodation facility assessment.
    Conclusions: This study indicated that the parameters obtained by the IFLIP system and the manual accommodation facility were comparable, and the IFLIP system had good sensitivity and specificity in the assessment of the accommodation facility, thus may serve as a promising tool for screening and diagnosis of binocular visual function anomalies in clinical and community settings.
    MeSH term(s) Humans ; Young Adult ; Adult ; Vision, Binocular ; Vision Tests ; Visual Acuity ; Accommodation, Ocular ; Sensitivity and Specificity
    Language English
    Publishing date 2023-07-03
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202306_32802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Conference proceedings: Mechanical engineering, manufacturing and automation technologies

    Chen, X. R

    selected, peer reviewed papers from the 2nd International Conference on Mechanical Design, Manufacturing and Automation (ICMDMA 2014), December 27-28, 2014, Huanggang, Hubei, China

    (Applied mechanics and materials ; 722)

    2015  

    Event/congress ICMDMA 2014 (2, 2014.12.27-28, Huanggang) ; International Conference on Mechanical Design, Manufacturing and Automation (2, 2014.12.27-28, Huanggang)
    Author's details ed. by X. R. Chen
    Series title Applied mechanics and materials ; 722
    Language English
    Size XIV, 453 S.
    Publisher ttp, Trans Tech Publ
    Publishing place Pfaffikon u.a.
    Document type Book ; Conference proceedings
    ISBN 9783038353980 ; 3038353981
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Article: [Primary coenzyme Q10 deficiency-7: a case report and literature review].

    Chen, X R / Xu, J P / Yao, Y H

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2020  Volume 58, Issue 11, Page(s) 928–932

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Ataxia/diagnosis ; Ataxia/genetics ; Child ; China ; Humans ; Infant ; Male ; Mitochondrial Diseases/diagnosis ; Mitochondrial Diseases/genetics ; Mitochondrial Proteins/genetics ; Muscle Weakness/diagnosis ; Muscle Weakness/genetics ; Mutation ; Ubiquinone/deficiency ; Ubiquinone/genetics
    Chemical Substances COQ4 protein, human ; Mitochondrial Proteins ; Ubiquinone (1339-63-5)
    Language Chinese
    Publishing date 2020-10-12
    Publishing country China
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20200610-00601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Chronic Obstructive Pulmonary Disease (COPD) management in the community: how could primary care team contribute?

    Chen, X R Catherine / Leung, S H / Li, Y C

    BMC family practice

    2020  Volume 21, Issue 1, Page(s) 184

    Abstract: Background: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease commonly encountered in primary care. This study aimed to audit COPD care at primary care clinics of Hong Kong and to work out improvement strategies.: Method: All ...

    Abstract Background: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease commonly encountered in primary care. This study aimed to audit COPD care at primary care clinics of Hong Kong and to work out improvement strategies.
    Method: All COPD patients aged 40 or above who had been followed up at 13 public primary care clinics of Kowloon Central Cluster (KCC) under the Hospital Authority of Hong Kong (HAHK) were included in this clinic audit. Evidence-based audit criteria and performance standards were established after thorough literature review. Phase 1 was from 1st April 2016 to 31st March 2017, with deficiencies of care identified. It was followed by a one-year implementation phase through which a series of improvement strategies were executed. Outcome of the enhancement was reviewed during Phase 2 from 1st April 2018 to 31st March 2019. Chi-square test and student's t test were used to detect statistically significant changes between Phase 1 and Phase 2.
    Results: A total of 2358 COPD cases were identified in Phase 1 where 658 of them were smokers. Of those smokers, 332 (50.5%) had been referred to Smoking Counselling and Cessation Service (SCCS) and 289 (43.9%) actually attended it. 991 cases (42%) received Seasonal Influenza Vaccine (SIV) and 938 cases (39.8%) received Pneumococcal Vaccine (PCV). 698 patients (29.6%) had spirometry done before and 423 patients (17.9%) had been admitted to hospital due to acute exacerbation of COPD (AECOPD). With the concerted effort taken during the implementation phase, Phase 2 data showed significant improvement in nearly all criteria. There was a marked increase in the SIV and PCV uptake rate, spirometry performance rate and most importantly, a significant reduction in AECOPD rate leading to hospital admission (13.5%, P = 0.000043). However, the referral rate and attendance rate of SCCS among smokers remained stagnant (P > 0.05).
    Conclusion: Via a systematic team approach, COPD care at primary care clinics of KCC under HAHK had been significantly improved for most of the audit criteria, which in turn reduced the burden of the healthcare system.
    MeSH term(s) Delivery of Health Care ; Humans ; Lung ; Primary Health Care ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Pulmonary Disease, Chronic Obstructive/therapy ; Spirometry
    Language English
    Publishing date 2020-09-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041495-X
    ISSN 1471-2296 ; 1471-2296
    ISSN (online) 1471-2296
    ISSN 1471-2296
    DOI 10.1186/s12875-020-01256-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Hypothyroidism caused by apatinib in patient with lung metastasis from rectal adenocarcinoma: a case report].

    Chen, X R / Chang, Z / Wang, H Q

    Zhonghua zhong liu za zhi [Chinese journal of oncology

    2019  Volume 41, Issue 12, Page(s) 959–960

    MeSH term(s) Adenocarcinoma/drug therapy ; Adenocarcinoma/pathology ; Antineoplastic Agents/therapeutic use ; Humans ; Hypothyroidism/chemically induced ; Lung Neoplasms/drug therapy ; Lung Neoplasms/secondary ; Pyridines/therapeutic use ; Rectal Neoplasms/drug therapy ; Rectal Neoplasms/pathology
    Chemical Substances Antineoplastic Agents ; Pyridines ; apatinib (5S371K6132)
    Language Chinese
    Publishing date 2019-12-18
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 603424-x
    ISSN 0253-3766
    ISSN 0253-3766
    DOI 10.3760/cma.j.issn.0253-3766.2019.12.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [A case of alimentary tract hemorrhage caused by Japanese red mushroom poisoning].

    Sun, Y Y / Chen, X R / Zhao, G J / Wu, B / Lu, Z Q

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2021  Volume 39, Issue 9, Page(s) 694–695

    MeSH term(s) Hemorrhage ; Humans ; Japan ; Mushroom Poisoning/complications
    Language Chinese
    Publishing date 2021-10-08
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 1050900-8
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.cn121094-20201027-00579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: One case of orbital apex syndrome caused by small cell lung cancer metastasis.

    Xu, L / Yu, M / Chen, X-R / Li, L-L / Ouyang, Q-R / Xiong, Q

    Revue neurologique

    2021  Volume 177, Issue 8, Page(s) 1032–1035

    MeSH term(s) Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/diagnostic imaging ; Orbital Diseases ; Orbital Neoplasms/complications ; Orbital Neoplasms/diagnosis ; Small Cell Lung Carcinoma/complications ; Small Cell Lung Carcinoma/diagnostic imaging ; Syndrome
    Language English
    Publishing date 2021-03-31
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 4593-7
    ISSN 2213-0004 ; 0035-3787
    ISSN (online) 2213-0004
    ISSN 0035-3787
    DOI 10.1016/j.neurol.2020.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Explaining recollection without remembering.

    Chen, X R / Gomes, C F A / Brainerd, C J

    Journal of experimental psychology. Learning, memory, and cognition

    2018  Volume 44, Issue 12, Page(s) 1921–1930

    Abstract: Recollection without remembering is a counterintuitive phenomenon that violates a traditional assumption of source memory models-namely, that accurate item memory is a necessary precondition for remembering source details that accompanied an item's ... ...

    Abstract Recollection without remembering is a counterintuitive phenomenon that violates a traditional assumption of source memory models-namely, that accurate item memory is a necessary precondition for remembering source details that accompanied an item's presentation. The dual-recollection model explains recollection without remembering as a by-product of the contrasting effects of target and context recollection on item tests versus source tests. We pitted that explanation against 2 others that preserve the traditional assumption, one based on hypothesized testing artifacts and the other derived from multivariate signal detection theory. Our experiments focused on a manipulation that, according to dual-recollection theory, should drive source memory and item memory in opposite directions. In 2 experiments, studied items were tagged with 3 source details (voice gender, taxonomic category, and list), such that either (a) the 3 details were consistent with each other or (b) 1 detail was inconsistent with the other 2. As predicted, source memory was better but item memory was worse when source details were consistent with each other. The recollection without remembering effect was observed in both experiments, and as predicted by dual-recollection theory, it was more robust when item memory was worse than when it was better. A further instance of recollection without remembering was detected that involved distractors rather than presented items. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
    MeSH term(s) Female ; Humans ; Male ; Mental Recall ; Models, Psychological ; Pattern Recognition, Physiological ; Reading ; Recognition (Psychology) ; Speech Perception ; Young Adult
    Language English
    Publishing date 2018-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 627313-0
    ISSN 1939-1285 ; 0278-7393
    ISSN (online) 1939-1285
    ISSN 0278-7393
    DOI 10.1037/xlm0000559
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Predictive values of serum 8-hydroxydeoxyguanosine on disease progression and prognosis of patients with sepsis].

    Chen, X R / Jiang, D W / Tang, Y H / Xu, C / Zhi, S C / Hong, G L / Lu, Z Q / Zhao, G J

    Zhonghua shao shang yu chuang mian xiu fu za zhi

    2022  Volume 38, Issue 3, Page(s) 207–214

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) 8-Hydroxy-2'-Deoxyguanosine ; Aged ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; ROC Curve ; Retrospective Studies ; Sepsis
    Chemical Substances 8-Hydroxy-2'-Deoxyguanosine (88847-89-6)
    Language Chinese
    Publishing date 2022-03-19
    Publishing country China
    Document type Journal Article ; Observational Study
    ISSN 2097-1109
    ISSN 2097-1109
    DOI 10.3760/cma.j.cn501120-20210910-00311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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