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  1. Article: Preparation of CS-LS/AgNPs Composites and Photocatalytic Degradation of Dyes.

    Wu, Jiabao / Chen, Xinpeng / Li, Aijing / Xing, Tieling / Chen, Guoqiang

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 5

    Abstract: Synthetic dyes are prone to water pollution during use, jeopardizing biodiversity and human health. This study aimed to investigate the adsorption and photocatalytic assist potential of sodium lignosulfonate (LS) in in situ reduced silver nanoparticles ( ... ...

    Abstract Synthetic dyes are prone to water pollution during use, jeopardizing biodiversity and human health. This study aimed to investigate the adsorption and photocatalytic assist potential of sodium lignosulfonate (LS) in in situ reduced silver nanoparticles (AgNPs) and chitosan (CS)-loaded silver nanoparticles (CS-LS/AgNPs) as adsorbents for Rhodamine B (RhB). The AgNPs were synthesized by doping LS on the surface of chitosan for modification. Fourier transform infrared (FT-IR) spectrometry, energy-dispersive spectroscopy (EDS), scanning electron microscopy (SEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) were used to confirm the synthesis of nanomaterials. The adsorption and photocatalytic removal experiments of RhB were carried out under optimal conditions (initial dye concentration of 20 mg/L, adsorbent dosage of 0.02 g, time of 60 min, and UV power of 250 W), and the kinetics of dye degradation was also investigated, which showed that the removal rate of RhB by AgNPs photocatalysis can reach 55%. The results indicated that LS was highly effective as a reducing agent for the large-scale production of metal nanoparticles and can be used for dye decolorization. This work provides a new catalyst for the effective removal of dye from wastewater, and can achieve high-value applications of chitosan and lignin.
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17051214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ubiquitination in the regulation of autophagy.

    Cen, Xueyan / Li, Ziling / Chen, Xinpeng

    Acta biochimica et biophysica Sinica

    2023  Volume 55, Issue 9, Page(s) 1348–1357

    Abstract: Autophagy, an efficient and effective approach to clear rapidly damaged organelles, macromolecules, and other harmful cellular components, enables the recycling of nutrient materials and supply of nutrients to maintain cellular homeostasis. ... ...

    Abstract Autophagy, an efficient and effective approach to clear rapidly damaged organelles, macromolecules, and other harmful cellular components, enables the recycling of nutrient materials and supply of nutrients to maintain cellular homeostasis. Ubiquitination plays an important regulatory role in autophagy. This paper summarizes the most recent progress in ubiquitin modification in various stages of autophagy, including initiation, elongation, and termination. Moreover, this paper shows that ubiquitination is an important way through which selective autophagy achieves substrate specificity. Furthermore, we note the distinction between monoubiquitination and polyubiquitination in the regulation of autophagy. Compared with monoubiquitination, polyubiquitination is a more common strategy to regulate the activity of the autophagy molecular machinery. In addition, the role of ubiquitination in the closure and fusion of autophagosomes warrants further study. This article not only clarifies the regulatory mechanism of autophagy but also contributes to a deeper understanding of the importance of ubiquitination modification.
    MeSH term(s) Autophagy ; Ubiquitination ; Autophagosomes ; Ubiquitin ; Cognition
    Chemical Substances Ubiquitin
    Language English
    Publishing date 2023-11-29
    Publishing country China
    Document type Journal Article
    ZDB-ID 2175256-4
    ISSN 1745-7270 ; 0582-9879 ; 1672-9145
    ISSN (online) 1745-7270
    ISSN 0582-9879 ; 1672-9145
    DOI 10.3724/abbs.2023149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Preparation of Fe

    Chen, Xinpeng / Li, Aijing / Yao, Ping / Wang, Jiapeng / Xing, Tieling / Chen, Guoqiang

    Langmuir : the ACS journal of surfaces and colloids

    2024  Volume 40, Issue 13, Page(s) 7147–7157

    Abstract: In this work, sea urchin-like magnetic ... ...

    Abstract In this work, sea urchin-like magnetic Fe
    Language English
    Publishing date 2024-03-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.4c00290
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Static sitting posture control during writing tasks in idiopathic scoliosis among freshmen.

    Xia, Qing / Chen, Xinpeng / Wei, Huanxia / Zhou, Guoliang / Dong, Jingmei

    Journal of orthopaedic surgery and research

    2023  Volume 18, Issue 1, Page(s) 735

    Abstract: Background: The posture control deficit is one important dysfunction in adolescent idiopathic scoliosis (AIS) patients, which is related to the development of the disease. However, it is not apparent whether AIS could affect static sitting posture ... ...

    Abstract Background: The posture control deficit is one important dysfunction in adolescent idiopathic scoliosis (AIS) patients, which is related to the development of the disease. However, it is not apparent whether AIS could affect static sitting posture control in late adolescence.
    Objective: This study aims to compare static sitting posture control in idiopathic scoliosis freshmen with normal peers to reveal possible differences in posture stability between them during writing tasks.
    Methods: In total, there were 10 AIS patients and 11 normal college students chosen for the writing task test. Data on the distribution of gluteal pressure during sitting were gathered. The comparison between these two groups was made using the independent sample t-test.
    Results: The total excursion (TE) of the center of pressure (COP) of the AIS group considerably increased in comparison with the control group (CON) (p = 0.029). The AIS group's average COP velocity in the anteroposterior (AP) direction was significantly higher than the CON group (p = 0.048). The peak gluteal pressure on the right side was significantly higher in the AIS group than in the CON group (p = 0.039). The right gluteal contact area dynamic variation was significantly higher in the AIS group compared to the CON group (p = 0.025).
    Conclusions: AIS patients showed increased gluteal pressure and lower sitting posture stability during writing tasks.
    MeSH term(s) Adolescent ; Humans ; Scoliosis ; Sitting Position ; Posture ; Kyphosis ; Postural Balance
    Language English
    Publishing date 2023-09-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2252548-8
    ISSN 1749-799X ; 1749-799X
    ISSN (online) 1749-799X
    ISSN 1749-799X
    DOI 10.1186/s13018-023-04228-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A biomechanical evaluation of firefighters' musculoskeletal loads when carrying self-contained breathing apparatus in walking and running.

    Wang, Shitan / Feng, Chenglong / Chen, Xinpeng / Shan, Mianjia / Niu, Wenxin

    Journal of safety research

    2023  Volume 87, Page(s) 1–14

    Abstract: Introduction: Musculoskeletal loading data are needed to design ergonomic intervention for firefighters. This study aimed to quantify the firefighters' musculoskeletal loads during self-contained breathing apparatus (SCBA) carriage and evaluate the ... ...

    Abstract Introduction: Musculoskeletal loading data are needed to design ergonomic intervention for firefighters. This study aimed to quantify the firefighters' musculoskeletal loads during self-contained breathing apparatus (SCBA) carriage and evaluate the effectiveness of shoulder strap length variation for the prevention of SCBA-related injuries.
    Method: Twelve firefighters (height: 174.6 ± 2.4 cm, mass: 67 ± 3.5 kg, BMI = 22 ± 1 kg/m
    Results: Walking with SCBA increased the rectus femoris force and hip reaction force by 34.92% [F = 53.629; p < 0.001; η
    Conclusions: Results revealed that rectus femoris activity, hip and knee exertion was sensitive to SCBA carriage. The variation of shoulder strap length has potential to influence the risk of low back pain (LBP).
    Practical applications: The findings suggest that fire services promote targeting physical training at firefighters' hip and knee regions. Test firefighters in this study were not advisable to adjust their shoulder strap at loose-fitting condition. The compatibility design of the trunk morphology and SCBA back-mounted frame was suggested for the management of LBP.
    MeSH term(s) Humans ; Firefighters ; Personal Protective Equipment ; Respiratory Protective Devices ; Running/physiology ; Walking/physiology ; Musculoskeletal System ; Musculoskeletal Physiological Phenomena ; Weight-Bearing/physiology
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Clinical Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2015321-1
    ISSN 1879-1247 ; 0022-4375
    ISSN (online) 1879-1247
    ISSN 0022-4375
    DOI 10.1016/j.jsr.2023.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The influence of high-order chromatin state in the regulation of stem cell fate.

    Chen, Xinpeng / Lin, Haiyan / Li, Guohong

    Biochemical Society transactions

    2022  

    Abstract: In eukaryotic cells, genomic DNA is hierarchically compacted by histones into chromatin, which is initially assembled by the nucleosome and further folded into orderly and flexible structures that include chromatin fiber, chromatin looping, topologically ...

    Abstract In eukaryotic cells, genomic DNA is hierarchically compacted by histones into chromatin, which is initially assembled by the nucleosome and further folded into orderly and flexible structures that include chromatin fiber, chromatin looping, topologically associated domains (TADs), chromosome compartments, and chromosome territories. These distinct structures and motifs build the three-dimensional (3D) genome architecture, which precisely controls spatial and temporal gene expression in the nucleus. Given that each type of cell is characterized by its own unique gene expression profile, the state of high-order chromatin plays an essential role in the cell fate decision. Accumulating evidence suggests that the plasticity of high-order chromatin is closely associated with stem cell fate. In this review, we summarize the biological roles of the state of high-order chromatin in embryogenesis, stem cell differentiation, the maintenance of stem cell identity, and somatic cell reprogramming. In addition, we highlight the roles of epigenetic factors and pioneer transcription factors (TFs) involved in regulating the state of high-order chromatin during the determination of stem cell fate and discuss how H3K9me3-heterochromatin restricts stem cell fate. In summary, we review the most recent progress in research on the regulatory functions of high-order chromatin dynamics in the determination and maintenance of stem cell fate.
    Language English
    Publishing date 2022-12-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 184237-7
    ISSN 1470-8752 ; 0300-5127
    ISSN (online) 1470-8752
    ISSN 0300-5127
    DOI 10.1042/BST20220763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: HAPLN3 inhibits apoptosis and promotes EMT of clear cell renal cell carcinoma via ERK and Bcl-2 signal pathways

    Ding, Yi / Xiong, Shida / Chen, Xinpeng / Pan, Qiufeng / Fan, Jiawen / Guo, Ju

    J Cancer Res Clin Oncol. 2023 Jan., v. 149, no. 1, p. 79-90

    2023  , Page(s) 79–90

    Abstract: Hyaluronan and proteoglycan link protein 3 (HAPLN3) is a member of the hyaluronan and proteoglycan link protein family expressed in the extracellular matrix closely associated with the development and occurrence of various malignant tumors; yet, its ... ...

    Abstract Hyaluronan and proteoglycan link protein 3 (HAPLN3) is a member of the hyaluronan and proteoglycan link protein family expressed in the extracellular matrix closely associated with the development and occurrence of various malignant tumors; yet, its function in clear cell renal cell cancer (ccRCC) is still poorly understood. The following study investigated the progress and mechanism of HAPLN3 on ccRCC using bioinformatics analysis and in vitro experiments. In order to determine whether HAPLN3 is differentially expressed in ccRCC, we analyzed data from the Cancer Genome Atlas (TCGA) and GSE40435 and further validated them in the Human Protein Atlas (HPA) database. Simultaneously, the TCGA dataset was utilized to study the relationship between HAPLN3 expression and the progression of ccRCC and its prognostic value in ccRCC. Gene enrichment analysis (GSEA) was used to explore HAPLN3-related signaling pathways in ccRCC. The TIMER database investigates the link for both HAPLN3 and immune cell infiltration. Different ccRCC cell lines the role of HAPLN3 on cell biological behavior in vitro. HAPLN3 was increased in ccRCC, and its high expression was related to the patients' survival rates and clinical characteristics. GSEA showed that HAPLN3 is mainly enriched in proliferative and metastatic pathways. In addition, HAPLN3 was an independently associated significant predictor in patients with ccRCC. Functional experiments demonstrated that HAPLN3 could promote the proliferation, migration, and invasion of ccRCC cells through the ERK1/2 signaling pathway. To sum up, our data suggest that HAPLN3 may serve as a new prognostic biomarker and potential therapeutic target for ccRCC.
    Keywords apoptosis ; bioinformatics ; biomarkers ; data collection ; databases ; extracellular matrix ; genes ; humans ; hyaluronic acid ; metastasis ; proteoglycans ; renal cell carcinoma ; therapeutics
    Language English
    Dates of publication 2023-01
    Size p. 79-90
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 134792-5
    ISSN 1432-1335 ; 0171-5216 ; 0084-5353 ; 0943-9382
    ISSN (online) 1432-1335
    ISSN 0171-5216 ; 0084-5353 ; 0943-9382
    DOI 10.1007/s00432-022-04421-3
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: One-step preparation of superhydrophobic cotton fabric based on thiol-ene click chemistry

    Chen, Xinpeng / Chu, Runshan / Xing, Tieling / Chen, Guoqiang

    Colloids and surfaces. 2021 Feb. 20, v. 611

    2021  

    Abstract: This study has attempted to use the click chemistry reaction, wherein vinyl trimethoxysilane (VTMS) and mercaptan react under ultraviolet (UV) light to produce a hydrophobic reagent and hydrolyse under appropriate conditions. The hydrolysed product is ... ...

    Abstract This study has attempted to use the click chemistry reaction, wherein vinyl trimethoxysilane (VTMS) and mercaptan react under ultraviolet (UV) light to produce a hydrophobic reagent and hydrolyse under appropriate conditions. The hydrolysed product is dehydrated and condensed with cotton fabric at high temperatures to obtain superhydrophobicity. Herein, the effect of different carbon chain length reactants on the hydrophobicity of cotton fabric was discussed, and it was found that different products showed different hydrophobicity. The static contact angle was 159°, and the sliding angle was 7.2°. The chemical structure and morphological changes of the surface of the fiber after the modification were characterised using Fourier-transform infrared, scanning electron microscopy, X-ray photoelectron spectroscopy, and energy-dispersive spectroscopy. The results showed that the surface of the modified cotton fiber was wrapped by a micron-level polymer resistant to UV, acids, acetone solvents, and water washing. Thus, this novel preparation approach developed a superhydrophobic cotton with multiple functions, such as self-cleaning and oil–water separation and has promising applications in complex fields.
    Keywords X-ray photoelectron spectroscopy ; acetone ; carbon ; chemical structure ; contact angle ; cotton fabric ; energy-dispersive X-ray analysis ; hydrolysis ; hydrophobicity ; lint cotton ; polymers
    Language English
    Dates of publication 2021-0220
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1500517-3
    ISSN 0927-7757
    ISSN 0927-7757
    DOI 10.1016/j.colsurfa.2020.125803
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Fabrication of Robust Superhydrophobic Polyester Fabrics with Photothermal Conversion and Oil-Water Separation Performance through Deposition of Natural Polyphenols.

    Chen, Xinpeng / Wang, Jiapeng / Xie, Ailing / Wang, Boan / Wu, Jiabao / Chen, Guoqiang / Xing, Tieling

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 44, Page(s) 15817–15827

    Abstract: Superhydrophobic polyester (PET) fabrics were created by increasing fabric surface roughness and decreasing surface energy through interactions between natural polyphenols, ferrous sulfate heptahydrate, and hexadecyltrimethoxysilane. The superhydrophobic ...

    Abstract Superhydrophobic polyester (PET) fabrics were created by increasing fabric surface roughness and decreasing surface energy through interactions between natural polyphenols, ferrous sulfate heptahydrate, and hexadecyltrimethoxysilane. The superhydrophobic fabric can be obtained with different natural polyphenols, including tannic acid, ferulic acid, gallic acid, guaiacol, and caffeic acid. Durability tests were carried out on the superhydrophobic PET fabric, investigating resistance to washing, rubbing, UV aging, acids, alkalis, and organic reagents. The results demonstrate the stability and versatility of modified PET in complex environments. The modified superhydrophobic PET fabric exhibited exceptional oil-water separation and self-cleaning properties, exhibiting a water contact angle of 161.3° and a sliding angle of 4°. In addition, the modified fabric demonstrated a remarkable photothermal conversion efficiency, with the surface temperature increasing from 29.1 to 72 °C in 300 s, and it maintained a degree of photothermal conversion capability even upon completion of four cycles. This study offers novel perspectives on extending the utilization of natural polyphenols for constructing durable, robust, and multifunctional superhydrophobic fabrics.
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c02508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The Role of Multifidus in the Biomechanics of Lumbar Spine: A Musculoskeletal Modeling Study.

    Wang, Kuan / Deng, Zhen / Chen, Xinpeng / Shao, Jiang / Qiu, Lulu / Jiang, Chenghua / Niu, Wenxin

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 1

    Abstract: Background: The role of multifidus in the biomechanics of lumbar spine remained unclear.: Purpose: This study aimed to investigate the role of multifidus in the modeling of lumbar spine and the influence of asymmetric multifidus atrophy on the ... ...

    Abstract Background: The role of multifidus in the biomechanics of lumbar spine remained unclear.
    Purpose: This study aimed to investigate the role of multifidus in the modeling of lumbar spine and the influence of asymmetric multifidus atrophy on the biomechanics of lumbar spine.
    Methods: This study considered five different multifidus conditions in the trunk musculoskeletal models: group 1 (with entire multifidus), group 2 (without multifidus), group 3 (multifidus with half of maximum isometric force), group 4 (asymmetric multifidus atrophy on L5/S1 level), and group 5 (asymmetric multifidus atrophy on L4/L5 level). In order to test how different multifidus situations would affect the lumbar spine, four trunk flexional angles (0°, 30°, 60°, and 90°) were simulated. The calculation of muscle activation and muscle force was done using static optimization function in OpenSim. Then, joint reaction forces of L5/S1 and L4/L5 levels were calculated and compared among the groups.
    Results: The models without multifidus had the highest normalized compressive forces on the L4/L5 level in trunk flexion tasks. In extreme cases produced by group 2 models, the normalized compressive forces on L4/L5 level were 444% (30° flexion), 568% (60° flexion), and 576% (90° flexion) of upper body weight, which were 1.82 times, 1.63 times, and 1.13 times as large as the values computed by the corresponding models in group 1. In 90° flexion, the success rate of simulation in group 2 was 49.6%, followed by group 3 (84.4%), group 4 (89.6%), group 5 (92.8%), and group 1 (92.8%).
    Conclusions: The results demonstrate that incorporating multifidus in the musculoskeletal model is important for increasing the success rate of simulation and decreasing the incidence of overestimation of compressive load on the lumbar spine. Asymmetric multifidus atrophy has negligible effect on the lower lumbar spine in the trunk flexion posture. The results highlighted the fine-tuning ability of multifidus in equilibrating the loads on the lower back and the necessity of incorporating multifidus in trunk musculoskeletal modeling.
    Language English
    Publishing date 2023-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10010067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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