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  1. Article: [Etiological treatment of central nervous system infection in children].

    Chen, Y H

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2022  Volume 60, Issue 2, Page(s) 166–168

    MeSH term(s) Central Nervous System Infections/drug therapy ; Child ; Humans ; Nervous System Malformations
    Language Chinese
    Publishing date 2022-01-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20211203-01018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Background and thoughts on"The optimal use of glucocorticoids for patients with chronic obstructive pulmonary disease: a Chinese expert consensus (2021)"].

    Chen, Y H

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

    2021  Volume 44, Issue 12, Page(s) 1034–1036

    MeSH term(s) Asians ; China ; Consensus ; Glucocorticoids/therapeutic use ; Humans ; Pulmonary Disease, Chronic Obstructive/drug therapy
    Chemical Substances Glucocorticoids
    Language Chinese
    Publishing date 2021-12-16
    Publishing country China
    Document type Journal Article
    ZDB-ID 1027965-9
    ISSN 1001-0939
    ISSN 1001-0939
    DOI 10.3760/cma.j.cn112147-20210929-00686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ovoid palatal patch: a portentous sign in dermatomyositis.

    Liu, H-L / Chen, Y-H

    QJM : monthly journal of the Association of Physicians

    2022  Volume 116, Issue 5, Page(s) 377–378

    MeSH term(s) Humans ; Dermatomyositis/diagnosis
    Language English
    Publishing date 2022-12-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcac279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Critical care management and thinking of perihematomal edema after intracerebral hemorrhage].

    Wang, R Z / Chen, Y H

    Zhonghua yi xue za zhi

    2022  Volume 102, Issue 29, Page(s) 2231–2235

    Abstract: The prognosis of patients with spontaneous intracerebral hemorrhage (sICH) is poor. It is of great significance to improve the neurological function of these patients and make them return to society. However, to date, no treatment has been proved to ... ...

    Abstract The prognosis of patients with spontaneous intracerebral hemorrhage (sICH) is poor. It is of great significance to improve the neurological function of these patients and make them return to society. However, to date, no treatment has been proved to significantly improve the neurological prognosis of sICH patients. The perihematomal edema (PHE) is a quantifiable marker of secondary brain injury (SBI) after ICH. It is associated with dysfunction of ion channels of vascular endothelial cells, inflammatory response induced-blood brain barrier dysfunction, and iron deposition caused by red blood cell degradation after ICH. Given that the space-occupying effect of PHE, the direct relation with SBI, long growth course and variable growth of PHE among individuals, interrupting the expansion of PHE has become a therapeutic target to improve neurological outcomes in ICH patients. Conducting an integrated and individualized strategy of critical care management and performing the corresponding pre-clinical and translational clinical research targeting the pathophysiological mechanism, nature course, and risk factors of PHE deserves further exploration.
    MeSH term(s) Brain Edema/etiology ; Brain Edema/therapy ; Cerebral Hemorrhage/complications ; Cerebral Hemorrhage/drug therapy ; Critical Care ; Edema/complications ; Endothelial Cells ; Humans
    Language Chinese
    Publishing date 2022-08-04
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20220429-00968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Etiologic diagnosis, treatment and prognosis of bacterial meningitis from the clinical features].

    Chen, Y H

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2019  Volume 57, Issue 10, Page(s) 743–745

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Humans ; Meningitis, Bacterial/diagnosis ; Meningitis, Bacterial/drug therapy ; Meningitis, Bacterial/etiology ; Meningitis, Bacterial/microbiology ; Prognosis
    Chemical Substances Anti-Bacterial Agents
    Language Chinese
    Publishing date 2019-10-08
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.issn.0578-1310.2019.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Applying Linguistic VIKOR and Entropy to Evaluate Competitive Ability of Medical Tourism in Taiwan

    Chen, Y. H.

    2nd IEEE Eurasia Conference on Biomedical Engineering, Healthcare and Sustainability 2020, ECBIOS 2020

    Abstract: Tourism is a high profit and low-cost industry Medical tourism is one kind of tourism type This kind of tourism type is high threshold and can bring more profit for government However, a few of literatures research about competitive ability of medical ... ...

    Abstract Tourism is a high profit and low-cost industry Medical tourism is one kind of tourism type This kind of tourism type is high threshold and can bring more profit for government However, a few of literatures research about competitive ability of medical tourism This study collects relative literature and interview some expert to design the criteria to evaluate competitive ability of medical tourism And then, linguistic VIKOR and Entropy are used to evaluate competitive ability of medical tourism among China, Taiwan, Japan, South Korea © 2020 IEEE
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #891468
    Database COVID19

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  7. Article: [The westward migration of Tongji Medical College during the Anti-Japanese War].

    Ke, Y P / Chen, Y H / Deng, J P

    Zhonghua yi shi za zhi (Beijing, China : 1980)

    2022  Volume 52, Issue 1, Page(s) 48–57

    Abstract: Tongji Medical College began its "education Long March" after the Battle of Shanghai in 1937, with six westward migrations across almost 10,000 kilometers over eight years. It first moved to the city of Shanghai because Tongji Medical College had to rent ...

    Abstract Tongji Medical College began its "education Long March" after the Battle of Shanghai in 1937, with six westward migrations across almost 10,000 kilometers over eight years. It first moved to the city of Shanghai because Tongji Medical College had to rent space in Shanghai, then moved to Jinhua in Zhejiang Province soon afterwards. After that it migrated to Ganzhou and Jian in Jiangxi Province, then He County in Guangxi Province and Kunming in Yunnan Province, ultimately locating in Li Village in Sichuan Province. Tongji Medical College was operated by Chinese and implemented high-level administration and teaching under the difficult conditions during the Anti-Japanese War. As a result, Tongji Medical College made advances in the medical field, such those by Professor Wu Mengchao. It also made advancements in research and treatment, such as identifying pathogenesis of a local epidemic and offering some treatment methods, and popularised medical knowledge for local people by exhibitions and news paper columns. It also established the Number One and the Number Five UMC Trauma Centre, participating in battlefield treatment. The German teachers of Tongji Medical College, who did not move to the west, established a German Medical School in Shanghai. Tongji Medical College returned back to Shanghai, incorporating the German Medical School in Shanghai after the Anti-Japanese War.
    MeSH term(s) China/epidemiology ; Epidemics ; Humans ; Knowledge ; Male ; Schools, Medical/history ; Universities/history
    Language Chinese
    Publishing date 2022-05-15
    Publishing country China
    Document type Journal Article
    ZDB-ID 1052411-3
    ISSN 0255-7053
    ISSN 0255-7053
    DOI 10.3760/cma.j.cn112155-20210122-00017-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Treatment strategy for gastrointestinal tumor under the outbreak of novel coronavirus pneumonia in China].

    Chen, Y H / Peng, J S

    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

    2020  Volume 23, Issue 2, Page(s) I–IV

    Abstract: The outbreak of the novel coronavirus pneumonia (NCP) has become a public health emergency in China. Chinese authorities and health agencies had devoted great efforts to control this disease. As surgeons specialized in the treatment of gastrointestinal ... ...

    Abstract The outbreak of the novel coronavirus pneumonia (NCP) has become a public health emergency in China. Chinese authorities and health agencies had devoted great efforts to control this disease. As surgeons specialized in the treatment of gastrointestinal tumors, we should always be aware of the prevention for NCP and incorporate this awareness into every detail of clinical practice. For the patients with gastrointestinal tumors, pre-admission screening should be done in order to rule out NCP. Real-time RT-PCR panel and chest CT scan should be conducted for patients with fever (>37.3℃), travel history to Hubei Province within 14 days, or contact history with residents from Wuhan district within 14 days. Prevention measures for both medical staffs and the screen-negative admitted patients should also be enhanced because false negative is possible. Medical instruments should be properly discarded or disinfected according to standardized procedures established by the local center for disease control and prevention (CDC). Surgical operation should be reduced at a minimal level to prevent cross infection in this special period.Surgical intervention for benign tumor should be postponed. For malignant tumor, multidisciplinary therapy (MDT) is recommended and non-surgical anti-tumor therapy should be selected with higher priority. Neoadjuvant therapy is highly recommended for gastrointestinal cancer at advanced stages that meet the indications of NCCN guideline (gastric cancer T stage ≥ 2/rectal cancer T stage ≥ 3/unresectable colon cancer). Gastric or esophagogastricjunction (EGJ) malignant tumor with obstruction can be managed with gastric tube decompression or stent placement to relieve the symptoms. Transnasal enteral feeding tube intubation/percutaneous endoscopic gastrostomy could be adopted to ensure enteral nutrition supply. For colorectal malignancy with simple intestinal obstruction, stent placement can achieve a high success rate, which not only helps avoid emergency surgery, but also creates a better condition for subsequent surgery. Transcatheter arterial embolization for hemostasis is an alternative choice for gastrointestinal tumor with bleeding. However, emergency operation still must be performed for patients with acute uncontrolled bleeding, obstruction or after other alternative treatment measures fail. All cases with suspicious or confirmed with NCP must be reported to the local CDC department. All invasive intervention must be performed in a designated isolation area. Tertiary prevention measure must be adopted for all anesthetists with additional face mask or medical goggle protection to prevent respiratory droplet transmission. Preventive enterostomy is preferable in lower digestive tract surgery. Thoroughly disinfecting the operating room after surgery is necessary. Fever after surgery must be carefully differentiated whether it's caused by post-surgery abdominal infection/inflammation or NCP. Single-room isolation and related examinations should be performed according to the standard procedures. We believe that with the unprecedentedly joint efforts of doctors and patients, we will eventually win this war against NCP.
    MeSH term(s) Betacoronavirus ; COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; China ; Clinical Laboratory Techniques ; Coronavirus ; Coronavirus Infections/diagnosis ; Coronavirus Infections/prevention & control ; Disease Outbreaks ; Humans ; Mass Screening ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/prevention & control ; Rectal Neoplasms/therapy ; Rectal Neoplasms/virology ; SARS-CoV-2
    Chemical Substances COVID-19 Vaccines ; Covid-19 aAPC vaccine
    Keywords covid19
    Language Chinese
    Publishing date 2020-02-18
    Publishing country China
    Document type Journal Article
    ISSN 1671-0274
    ISSN 1671-0274
    DOI 10.3760/cma.j.issn.1671-0274.2020.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Predicting adverse drug effects: A heterogeneous graph convolution network with a multi-layer perceptron approach.

    Chen, Y-H / Shih, Y-T / Chien, C-S / Tsai, C-S

    PloS one

    2022  Volume 17, Issue 12, Page(s) e0266435

    Abstract: We apply a heterogeneous graph convolution network (GCN) combined with a multi-layer perceptron (MLP) denoted by GCNMLP to explore the potential side effects of drugs. Here the SIDER, OFFSIDERS, and FAERS are used as the datasets. We integrate the drug ... ...

    Abstract We apply a heterogeneous graph convolution network (GCN) combined with a multi-layer perceptron (MLP) denoted by GCNMLP to explore the potential side effects of drugs. Here the SIDER, OFFSIDERS, and FAERS are used as the datasets. We integrate the drug information with similar characteristics from the datasets of known drugs and side effect networks. The heterogeneous graph networks explore the potential side effects of drugs by inferring the relationship between similar drugs and related side effects. This novel in silico method will shorten the time spent in uncovering the unseen side effects within routine drug prescriptions while highlighting the relevance of exploring drug mechanisms from well-documented drugs. In our experiments, we inquire about the drugs Vancomycin, Amlodipine, Cisplatin, and Glimepiride from a trained model, where the parameters are acquired from the dataset SIDER after training. Our results show that the performance of the GCNMLP on these three datasets is superior to the non-negative matrix factorization method (NMF) and some well-known machine learning methods with respect to various evaluation scales. Moreover, new side effects of drugs can be obtained using the GCNMLP.
    MeSH term(s) Humans ; Neural Networks, Computer ; Algorithms ; Drug-Related Side Effects and Adverse Reactions ; Machine Learning
    Language English
    Publishing date 2022-12-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0266435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [GNB2L1 gene expression and clinical value in hepatocellular carcinoma based on bioinformatics].

    Fan, L Y / Sun, C L / Chen, Y H / Gao, G S

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2022  Volume 30, Issue 9, Page(s) 954–961

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/pathology ; Computational Biology ; Liver Neoplasms/pathology ; Protein Subunits/genetics ; Protein Subunits/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; RNA, Messenger ; Guanine Nucleotides ; Gene Expression ; Biomarkers, Tumor/genetics
    Chemical Substances Protein Subunits ; RNA, Messenger ; Guanine Nucleotides ; Biomarkers, Tumor
    Language Chinese
    Publishing date 2022-10-27
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20211014-00509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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