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  1. Book ; Online: Soil Degradation, Soil Pollution and Ecological Restoration

    Sun, Bo / Liu, Ming / Chen, Yan

    2023  

    Keywords Research & information: general ; coal mining ; soil reclamation ; bacterial community ; bacterial diversity ; high-throughput sequencing ; farmland consolidation ; cultivated land quality ; soil basic physical and chemical properties ; heavy metals ; microorganisms ; karst areas ; soil depth ; land use types ; soil metal elements ; soil enzyme activity ; soil fungal community and diversity ; soil erodibility ; saturated hydraulic conductivity ; soil nutrients ; opencast coalmine ; Loess Plateau ; GLCM ; texture feature ; soda saline-alkali soil ; soil surface crack ; Songnen Plain ; antibiotics in soils ; microbial community ; soil degradation ; soil oxidoreductases ; compost fertility ; industries of concern ; source apportionment ; spatial patterns ; prevention distance ; soil health ; biochar ; manure ; soil structure ; vertisol ; agricultural environment ; soil and water resources ; agricultural engineering ; synergetic development strategy ; soil ; absolute altitude ; Jaworzyna Krynicka ; contamination
    Language English
    Size 1 electronic resource (202 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030645461
    ISBN 9783036589589 ; 3036589589
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: The Relationship Between Personality Traits, Emotional Stability and Mental Health in Art Vocational and Technical College Students During Epidemic Prevention and Control.

    Chen, Yan Ni

    Psychology research and behavior management

    2023  Volume 16, Page(s) 2857–2867

    Abstract: Objective: To investigate the relationship between the personality traits, emotional stability and mental health state of students in vocational and technical colleges of art under epidemic prevention and control based on latent trait-state theory.: ... ...

    Abstract Objective: To investigate the relationship between the personality traits, emotional stability and mental health state of students in vocational and technical colleges of art under epidemic prevention and control based on latent trait-state theory.
    Methods: Using the stratified sampling method, we selected 1569 students in vocational and technical colleges of art as research subjects. From 1 April 2022 to 5 April 2022, we conducted an online survey using the Eysenck Personality Questionnaire (Adult Edition) (EPQA), Emotional Stability Self-Test Scale and University Personality Inventory (UPI) to analyse the relationship between the traits, emotional stability and mental health of students in vocational and technical colleges of art.
    Results: For the EPQA personality traits, boys had lower extraversion and introversion scores than girls (47.71 ± 11.23 vs 49.06 ± 10.74,
    Conclusion: There is a close relationship between personality traits, emotional stability and mental health. Under the condition of epidemic prevention and control, strengthening the management of the self-emotional stability of students in vocational and technical colleges of art is helpful in improving students' mental health.
    Language English
    Publishing date 2023-07-26
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2495093-2
    ISSN 1179-1578
    ISSN 1179-1578
    DOI 10.2147/PRBM.S417243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Retraction Note: The green wave for climate: overcoming financial intermediation challenges in climate change mitigation through credit subsidies.

    Chen, Yan / Wang, Yan

    Environmental science and pollution research international

    2024  Volume 31, Issue 15, Page(s) 23287

    Language English
    Publishing date 2024-03-12
    Publishing country Germany
    Document type Retraction of Publication
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32883-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  4. Article ; Online: Generative AI in Medical Practice: In-Depth Exploration of Privacy and Security Challenges.

    Chen, Yan / Esmaeilzadeh, Pouyan

    Journal of medical Internet research

    2024  Volume 26, Page(s) e53008

    Abstract: As advances in artificial intelligence (AI) continue to transform and revolutionize the field of medicine, understanding the potential uses of generative AI in health care becomes increasingly important. Generative AI, including models such as generative ...

    Abstract As advances in artificial intelligence (AI) continue to transform and revolutionize the field of medicine, understanding the potential uses of generative AI in health care becomes increasingly important. Generative AI, including models such as generative adversarial networks and large language models, shows promise in transforming medical diagnostics, research, treatment planning, and patient care. However, these data-intensive systems pose new threats to protected health information. This Viewpoint paper aims to explore various categories of generative AI in health care, including medical diagnostics, drug discovery, virtual health assistants, medical research, and clinical decision support, while identifying security and privacy threats within each phase of the life cycle of such systems (ie, data collection, model development, and implementation phases). The objectives of this study were to analyze the current state of generative AI in health care, identify opportunities and privacy and security challenges posed by integrating these technologies into existing health care infrastructure, and propose strategies for mitigating security and privacy risks. This study highlights the importance of addressing the security and privacy threats associated with generative AI in health care to ensure the safe and effective use of these systems. The findings of this study can inform the development of future generative AI systems in health care and help health care organizations better understand the potential benefits and risks associated with these systems. By examining the use cases and benefits of generative AI across diverse domains within health care, this paper contributes to theoretical discussions surrounding AI ethics, security vulnerabilities, and data privacy regulations. In addition, this study provides practical insights for stakeholders looking to adopt generative AI solutions within their organizations.
    MeSH term(s) Humans ; Artificial Intelligence ; Privacy ; Biomedical Research ; Data Collection ; Language
    Language English
    Publishing date 2024-03-08
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/53008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Network Pharmacology Prediction and Molecular Docking-Based Strategy to Explore the Potential Mechanism of Gualou Xiebai Banxia Decoction against Myocardial Infarction.

    Wang, Wei-Lu / Chen, Yan

    Genes

    2024  Volume 15, Issue 4

    Abstract: The aim of this study was to investigate targets through which Gualou Xiebai Banxia decoction aids in treating myocardial infarction (MI) using network pharmacology in combination with molecular docking. The principal active ingredients of Gualou Xiebai ... ...

    Abstract The aim of this study was to investigate targets through which Gualou Xiebai Banxia decoction aids in treating myocardial infarction (MI) using network pharmacology in combination with molecular docking. The principal active ingredients of Gualou Xiebai Banxia decoction were identified from the TCMSP database using the criteria of drug-likeness ≥30% and oral bioavailability ≥0.18. Interactions and pathway enrichment were investigated using protein-protein interaction (PPI) networks and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, respectively. Active component structures were docked with those of potential protein targets using AutoDock molecular docking relative softwares. HIF1A was of particular interest as it was identified by the PPI network, GO and KEGG pathway enrichment analyses. In conclusion, the use of network pharmacology prediction and molecular docking assessments provides further information on the active components and mechanisms of action Gualou Xiebai Banxia decoction.
    MeSH term(s) Molecular Docking Simulation ; Myocardial Infarction/drug therapy ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Protein Interaction Maps/drug effects ; Network Pharmacology ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/chemistry
    Chemical Substances Drugs, Chinese Herbal ; Hypoxia-Inducible Factor 1, alpha Subunit
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes15040392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Progress in the Genetic Detection of Thalassemia Based on Third-Generation Gene Sequencing --Review].

    Chen, Yan-Jun / Xu, Zhi-Hong

    Zhongguo shi yan xue ye xue za zhi

    2024  Volume 32, Issue 2, Page(s) 634–638

    Abstract: Thalassemia is most widely distributed single gene autosome recessive genetic disease in the world, whose clinical manifestation was changed from asymptomatic anemia to severe anemia requiring continous blood transfusion to maintain life, thus resulting ... ...

    Abstract Thalassemia is most widely distributed single gene autosome recessive genetic disease in the world, whose clinical manifestation was changed from asymptomatic anemia to severe anemia requiring continous blood transfusion to maintain life, thus resulting in a serious economic burden to society and families. Therefore, it is necessary to carry out the corresponding prentatal screening and diagnosis. Most of the conventional detection methods can only detect the common thalassemia genotype, it can easy to cause misdiagnosis or missed diagnosis for those rate genetic variantions. The third-generation sequecing (TGS) has been applied to the detection of thalassemia genes, which is more accurate, reliable and superior to the converntional detection methods. This article reviews the latest research progress of the TGS technology in genetic testing of thalassemia.
    MeSH term(s) Humans ; Thalassemia/genetics ; Thalassemia/diagnosis ; Genetic Testing ; Genotype ; Sequence Analysis, DNA ; High-Throughput Nucleotide Sequencing ; Mutation
    Language Chinese
    Publishing date 2024-04-25
    Publishing country China
    Document type Journal Article ; Review ; English Abstract
    ZDB-ID 2404306-0
    ISSN 1009-2137
    ISSN 1009-2137
    DOI 10.19746/j.cnki.issn.1009-2137.2024.02.047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6603: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Book ; Online: Motion Structures

    You, Zhong / Chen, Yan

    Deployable Structural Assemblies of Mechanisms

    2012  

    Keywords Civil engineering, surveying & building ; Structural engineering ; angle ; assembly ; closure ; compact ; folding ; joint ; linkage ; mobile ; pivoting ; revolute
    Language 0|e
    Size 1 electronic resource (168 pages)
    Publisher Taylor and Francis
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021609283
    ISBN 9780429176463 ; 0429176465
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Article ; Online: Pre-Trained Joint Model for Intent Classification and Slot Filling with Semantic Feature Fusion.

    Chen, Yan / Luo, Zhenghang

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 5

    Abstract: The comprehension of spoken language is a crucial aspect of dialogue systems, encompassing two fundamental tasks: intent classification and slot filling. Currently, the joint modeling approach for these two tasks has emerged as the dominant method in ... ...

    Abstract The comprehension of spoken language is a crucial aspect of dialogue systems, encompassing two fundamental tasks: intent classification and slot filling. Currently, the joint modeling approach for these two tasks has emerged as the dominant method in spoken language understanding modeling. However, the existing joint models have limitations in terms of their relevancy and utilization of contextual semantic features between the multiple tasks. To address these limitations, a joint model based on BERT and semantic fusion (JMBSF) is proposed. The model employs pre-trained BERT to extract semantic features and utilizes semantic fusion to associate and integrate this information. The results of experiments on two benchmark datasets, ATIS and Snips, in spoken language comprehension demonstrate that the proposed JMBSF model attains 98.80% and 99.71% intent classification accuracy, 98.25% and 97.24% slot-filling F1-score, and 93.40% and 93.57% sentence accuracy, respectively. These results reveal a significant improvement compared to other joint models. Furthermore, comprehensive ablation studies affirm the effectiveness of each component in the design of JMBSF.
    MeSH term(s) Semantics ; Language ; Natural Language Processing ; Intention ; Acoustic Stimulation
    Language English
    Publishing date 2023-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23052848
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Radial Planes in Hip Magnetic Resonance Imaging: Techniques, Applications, and Perspectives.

    Chen, Yan-Li / Chen, Wei

    Journal of magnetic resonance imaging : JMRI

    2023  

    Abstract: The hip cartilage and labrum, as the main targets of femoroacetabular impingement, sports-related or traumatic damage, as well as congenital and developmental abnormalities, have attracted increasing attention with the development of magnetic resonance ... ...

    Abstract The hip cartilage and labrum, as the main targets of femoroacetabular impingement, sports-related or traumatic damage, as well as congenital and developmental abnormalities, have attracted increasing attention with the development of magnetic resonance imaging (MRI) and hip arthroscopy. MRI is a commonly used imaging modality to noninvasively visualize the hip cartilage and labral lesions. However, conventional orthogonal MRI planes encounter unique challenges given the ball-and-socket configuration of the hip joint, its anatomically abducted and anteverted orientation, and the thin, closely apposed cartilage enveloping the femoral head and acetabulum. Advancements in hip MRI's radial plane, which is acquired through the center of the hip joint, offer a solution. This technology provides true cross-sectional images of the cartilage and labrum perpendicular to the curvature of the joint, thereby mitigating the partial-volume-averaging effects. The integration of 3.0-Tesla high field strength and three-dimensional (3D) acquisition techniques further enhances the capabilities of the radial plane. This combination yields a high signal-to-noise ratio, high spatial resolution, high contrast between intraarticular structures, while minimizing partial-volume-averaging effects. Such improvements potentially facilitate the comprehensive detection of even minor chondral and labral lesions. The capability for multiplanar reconstruction from a single 3D volumetric acquisition further strengthens the usefulness of the radial plane by aiding in precise localization of hip cartilage and labral lesions, in line with hip arthroscopy findings. These advancements have the potential to standardize MRI evaluations and radiographic reporting systems for hip cartilage and labrum, offering precise guidance for hip arthroscopy. This article presents a comprehensive review of radial plane technology applied to the hip MRI, and discusses the morphological assessment and localization of hip cartilage and labral lesions utilizing this advanced imaging technique. EVIDENCE LEVEL: 5 TECHNICAL EFFICACY: Stage 2.
    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1146614-5
    ISSN 1522-2586 ; 1053-1807
    ISSN (online) 1522-2586
    ISSN 1053-1807
    DOI 10.1002/jmri.29029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3648: Show issues Location:
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  10. Article ; Online: LAMP5 may promote MM progression by activating p38.

    Chen, Yan / Ma, Tao

    Pathology oncology research : POR

    2023  Volume 29, Page(s) 1611083

    Abstract: Multiple myeloma (MM) is the second most common tumor of the hematologic system. MM remains incurable at this time. In this study, we used bioinformatics analysis to find key genes in the pathogenesis of MM. We first found that Lysosome associated ... ...

    Abstract Multiple myeloma (MM) is the second most common tumor of the hematologic system. MM remains incurable at this time. In this study, we used bioinformatics analysis to find key genes in the pathogenesis of MM. We first found that Lysosome associated membrane protein 5 (LAMP5) expression was sequentially increased in healthy donors (HD), monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM) and newly diagnosed MM (NDMM), relapsed MM (RMM). We collected bone marrow from patients with NDMM, HD and post-treatment MM (PTMM) and performed qPCR analysis of LAMP5, and found that the expression of LAMP5 is stronger in NDMM than in HD, and decreases after treatment. Western blotting assay also found more expression of LAMP5 in NDMM than in HD. Patients with high LAMP5 expression have a higher DS (Durie-Salmon) stage and worse prognosis. We next verified the expression of LAMP5 in four MM cell lines and silenced LAMP5 expression in RPMI-8226 and AMO-1, and explored the effects of LAMP5 silencing on MM cell apoptosis and cell cycle by flow cytometry and western blotting. Knockdown of LAMP5 promoted apoptosis in MM cells, but had no effect on the cell cycle. Mechanistically, LAMP5 may exert its pro-tumor effects in MM in part through activation of p38 protein. We screened LAMP5 for the first time as a key gene for MM progression and recurrence, and found that LAMP5 may exert its pro-tumor effects in MM through activation of p38 protein.
    MeSH term(s) Humans ; Multiple Myeloma/pathology ; Bone Marrow/metabolism ; Monoclonal Gammopathy of Undetermined Significance/diagnosis ; Monoclonal Gammopathy of Undetermined Significance/metabolism ; Monoclonal Gammopathy of Undetermined Significance/pathology ; Prognosis ; Disease Progression ; Lysosomal Membrane Proteins/genetics ; Lysosomal Membrane Proteins/metabolism
    Chemical Substances LAMP5 protein, human ; Lysosomal Membrane Proteins
    Language English
    Publishing date 2023-03-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1375979-6
    ISSN 1532-2807 ; 1219-4956
    ISSN (online) 1532-2807
    ISSN 1219-4956
    DOI 10.3389/pore.2023.1611083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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